Genetic and phenotypic heterogeneity in ovarian failure: overview of selected candidate genes.

abstract：:Nicotine has been found to improve memory performance in a variety of tests in rats, monkeys, and humans. Interactions of nicotinic systems with dopamine (DA) systems may be important for this effect. We conducted a series of studies of nicotinic agonist and antagonist interactions with DA systems using rats in a win-...

journal_title：Annals of the New York Academy of Sciences

authors： Levin ED,Rose JE

更新日期：1995-05-10 00:00:00

abstract：:Genome architecture is well diversified among eukaryotes in terms of size and content, with many being radically shaped by ancient and ongoing genome conflicts with transposable elements (e.g., the large transposon-rich genomes common among plants). In ciliates, a group of microbial eukaryotes with distinct somatic an...

journal_title：Annals of the New York Academy of Sciences

authors： Maurer-Alcalá XX,Nowacki M

更新日期：2019-07-01 00:00:00

abstract：:Though several studies show that genetic factors influence individual differences in musical engagement, aptitude, and achievement, no study to date has investigated whether specialization among musically active individuals in terms of choice of instrument and genre is heritable. Using a large twin cohort, we explored...

journal_title：Annals of the New York Academy of Sciences

authors： Mosing MA,Ullén F

更新日期：2018-05-09 00:00:00

abstract：:Endometriosis is a common gynecologic disorder that affects approximately 14% of all women and 30% to 50% of infertile women. Since the most common symptoms of endometriosis--progressive dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility--are also symptoms of multiple disorders, a diagnosis of endometrios...

journal_title：Annals of the New York Academy of Sciences

authors： Rice VM

更新日期：2002-03-01 00:00:00

abstract：:We studied 13 patients with unilateral peripheral vestibular lesions following removal of acoustic neurinomas. The time constant of the VOR after surgery was 6.4 +/- 2.6 seconds (normal is 18.5 +/- 7.7 seconds). The time constant of OKAN after surgery was 7.2 +/- 1.8 seconds (normal is 11.3 +/- 3.2 seconds). The mean ...

journal_title：Annals of the New York Academy of Sciences

authors： Hain TC,Zee DS

更新日期：1992-05-22 00:00:00

abstract：:The in vitro lethal activity of two Bacillus thuringiensis strains (IB-16 and IB-61) against Haemonchus contortus histotropic fourth stage larvae (L(4)) was evaluated. Each B. thuringiensis strain was used as soluble proteins at different concentrations. In addition, the in vitro lethal dose (LD(50)) of each strain wa...

journal_title：Annals of the New York Academy of Sciences

authors： Hernández Linares I,López Arellano ME,Mendoza de Gives P,Liébano Hernández E,de la Parra AB

更新日期：2008-12-01 00:00:00

abstract：:Marisa cornuarietis (Mollusc), Hyalella azteca (Crustacean), and Paracentrotus lividus (Echinoderm) demonstrated the ability to metabolize androgens through different pathways catalyzed by 5alpha-reductases (5alpha-R), hydroxysteroid dehydrogenases (HSD), hydroxylases, sulfotransferases (SULT), and fatty-acid acyl-CoA...

journal_title：Annals of the New York Academy of Sciences

authors： Janer G,Leblanc GA,Porte C

更新日期：2005-04-01 00:00:00

abstract：:Acylated aldose dialkyl dithioacetals with bromine undergo replacement of one alkylthio group by bromine. These unstable bromides react, as by fusion with 2,4-bis(trimethylsilyloxy)pyrimidine, to give acylated 1-(pyrimidin-1-yl) derivatives that upon saponification afford acyclic sugar nucleoside analogues, some as se...

journal_title：Annals of the New York Academy of Sciences

authors： Horton D,Baker DC,Kokrady SS

更新日期：1975-08-08 00:00:00

abstract：:We have described a family of adrenocortical tumor cell mutants (including clones OS3, Y6, and 10r9) that are resistant to ACTH because they fail to express the gene encoding the ACTH receptor (MC2R). The MC2R deficiency results from a mutation that impairs the activity of the nuclear receptor steroidogenic factor 1 (...

journal_title：Annals of the New York Academy of Sciences

authors： Schimmer BP,Cordova M,Tsao J,Frigeri C

更新日期：2003-06-01 00:00:00

abstract：:The concepts of the ventral striatopallidal system and extended amygdala have significantly improved our understanding of basal forebrain organization. As a result of these and other advances during the last twenty years, many of the most prominent basal forebrain structures, including the nucleus accumbens, olfactory...

journal_title：Annals of the New York Academy of Sciences

authors： de Olmos JS,Heimer L

更新日期：1999-06-29 00:00:00

abstract：:Three distinct pathological conditions, related to different means by which dense intralabyrinthine particles interfere with the function of a semicircular canal and cause nystagmus and vertigo, are amenable to treatment with repositioning maneuvers. Known as benign paroxysmal positional vertigo and variants, these co...

journal_title：Annals of the New York Academy of Sciences

authors： Epley JM

更新日期：2001-10-01 00:00:00

abstract：:This paper explores aspects of the role that laboratory instruments have played in establishing psychology as a science. Comparisons of earlier instruments with their more modern counterparts indicate that many problems and methods still of interest today were explored in the laboratories of psychology's pioneers. Suc...

journal_title：Annals of the New York Academy of Sciences

authors： Caudle FM

更新日期：1983-01-01 00:00:00

abstract：:This literature review of contemporary mentoring delineates mentoring definitions and anchors these with explanatory discourse. Select empirical studies spanning 1983-2019 were analyzed, with a focus on education across grade levels. Alternative mentoring issues, types, and applications, also located, are integral to ...

journal_title：Annals of the New York Academy of Sciences

authors： Mullen CA,Klimaitis CC

更新日期：2021-01-01 00:00:00

abstract：:Morphogenesis in the animal kingdom is closely coupled with the intracellular synthesis and the extracellular deposition of collagen. These morphogenetically important events involve multiple steps which begin in compartments inside the cell and continue in compartments outside the cell. The movement of matrix compone...

journal_title：Annals of the New York Academy of Sciences

authors： Birk DE,Trelstad RL

更新日期：1985-01-01 00:00:00

abstract：:The article summarizes reports on the concurrence of Klinefelter's syndrome (KS) with inflammatory rheumatic diseases, rheumatoid arthritis (RA), juvenile idiopathic arthritis, psoriatic arthritis, polymyositis/dermatomyositis, systemic lupus erythematosus, systemic sclerosis, mixed connective tissue disease, the anti...

journal_title：Annals of the New York Academy of Sciences

authors： Rovenský J,Imrich R,Lazúrová I,Payer J

更新日期：2010-04-01 00:00:00

abstract：:A trial was carried out in alpacas (Lama pacos) and llamas (Lama glama) to determine the economic benefits of controlling both external and internal parasites by the use of ivermectin ("Ivomec," Merck Sharp & Dohme). After four months the treated male alpacas gained on average 3.1 kg more than the untreated males, and...

journal_title：Annals of the New York Academy of Sciences

authors： Windsor RS,Windsor RH,Teran M

更新日期：1992-06-16 00:00:00

abstract：:Recent in vivo studies suggest a role for relaxin-3 in feeding and stress. To further elucidate the function of relaxin-3 in the central nervous system, we have employed a complementary approach, based on RNA interference, to modulate relaxin-3 expression. We have designed, constructed, and characterized three microRN...

journal_title：Annals of the New York Academy of Sciences

authors： Callander GE,Thomas WG,Bathgate RA

更新日期：2009-04-01 00:00:00

abstract：:The adult respiratory distress syndrome (ARDS) is not confined only to late shock states but is a typical finding in intoxications with such oxidizing agents as O3, NO2, chlorate, or paraquat. Under experimental conditions, alpha-tocopherol in a high enteric dosage (2 x 50 mg/kg) was able to prevent alterations of pul...

journal_title：Annals of the New York Academy of Sciences

authors： Wolf HR,Seeger HW

更新日期：1982-01-01 00:00:00

abstract：:The disturbances in the balance of pro- and antifibrinolytic activity, as observed in AAA and obesity, respectively, have considerable potential for influencing both intra- and extravascular fibrinolytic events and may be causally related to the development of vascular disease. For example, the wall of the aortic athe...

journal_title：Annals of the New York Academy of Sciences

authors： Samad F,Schneiderman J,Loskutoff D

更新日期：1997-04-15 00:00:00

abstract：:This article reviews some of the early work that has been performed to investigate the potential roles of circulating nucleic acids as prediction markers in acute illness and injury. Circulating DNA and RNA concentrations are elevated early in patients with trauma, stroke and ACS, and are generally highest in patients...

journal_title：Annals of the New York Academy of Sciences

authors： Rainer TH,Lam NY

更新日期：2006-09-01 00:00:00

abstract：:Older age is associated with functional declines throughout the body, including some aspects of cognitive performance. While dementia develops in only some elderly individuals, declines in cognitive functioning have an impact on daily living for many others. There are individual differences in age-related cognitive ch...

journal_title：Annals of the New York Academy of Sciences

authors： Moffat SD

更新日期：2005-12-01 00:00:00

abstract：:Reproduction usually is characterized by a mean-population fecundity pattern. Such a pattern has a maximum at earlier ages and a subsequent gradual decline in egg production. It is shown that individual fecundity trajectories do not follow such a pattern. In particular, the regular individual fecundity pattern has no ...

journal_title：Annals of the New York Academy of Sciences

authors： Novoseltsev VN,Arking R,Carey JR,Novoseltseva JA,Yashin AI

更新日期：2004-06-01 00:00:00

abstract：:We have developed an assay to detect mucosally delivered antibody to Cryptosporidium parvum sporozoite antigens. We absorbed a recombinant 23-kD sporozoite protein to polystyrene microspheres, and used flow cytometry to detect, titer, and determine the isotype of antibody to p23 that was shed in the feces of experimen...

journal_title：Annals of the New York Academy of Sciences

authors： Wyatt CR,Perryman LE

更新日期：2000-01-01 00:00:00

abstract：:Controls and calibrators in autoimmune assays are typically developed from patient sera. However, the use of sera is accompanied by a number of disadvantages, such as lack of monospecificity, lack of assay comparability, and supply limitations. Ideally, the control reagent would be an antigen-specific human monoclonal...

journal_title：Annals of the New York Academy of Sciences

authors： Knappik A,Capuano F,Frisch C,Ylera F,Bonelli F

更新日期：2009-09-01 00:00:00

abstract：:Pituitary adenylate cyclase-activating polypeptide (PACAP) is a structurally highly conserved neuropeptide and displays pleiotropic activity, including functioning as a neurotransmitter, neuromodulator, and neurotrophic factor. A series of recent experiments, including genetic manipulation of PACAP and its receptors, ...

journal_title：Annals of the New York Academy of Sciences

authors： Hashimoto H,Shintani N,Baba A

更新日期：2006-07-01 00:00:00

abstract：:The search for molecules on the surface of mammalian sperm that are responsible for the binding of sperm to the zona pellucida has led to the identification of a number of different surface proteins. Different experimental approaches have been used to identify these proteins and the strength of the evidence for their ...

journal_title：Annals of the New York Academy of Sciences

authors： Myles DG,Primakoff P

更新日期：1991-01-01 00:00:00

abstract：:Fungal pathogens are a growing threat to public health. As human immunodeficiency becomes increasingly common, fungal infections are becoming more prevalent. The use of antifungal agents for prophylaxis and treatment of fungal infections has favored the emergence of previously rare or unidentified species of drug-resi...

journal_title：Annals of the New York Academy of Sciences

authors： Geddes-McAlister J,Shapiro RS

更新日期：2019-01-01 00:00:00

abstract：:In rats, arginine vasopressin augments bradycardia associated with baroreflex activation. We investigated whether modulation of peripheral cardiac parasympathetic nerve function by AVP may play a role in this effect. To accomplish this we utilized an in vivo model with which we previously demonstrated both adrenergic ...

journal_title：Annals of the New York Academy of Sciences

authors： Pardini BJ,Lund DD,Schmid PG

更新日期：1993-07-22 00:00:00

abstract：:This study surveyed serum concentrations of vitamins, electrolytes, and trace elements in subjects seropositive for HIV-1 by ELISA and confirmatory Western blot. Thirty subjects (26 males, 4 females) were recruited at a hospital clinic. Seventeen were classified as having mild or severe ARC (AIDS-related complex), 7 h...

journal_title：Annals of the New York Academy of Sciences

authors： Bogden JD,Baker H,Frank O,Perez G,Kemp F,Bruening K,Louria D

更新日期：1990-01-01 00:00:00

abstract：:Results of therapeutic trials of transfer factor in a number of laboratories suggest clinical benefit and enhancement of immunological reactivity in patients with primary or secondary immunodeficiency diseases. Long term follow-up of 32 patients with the Wiskott-Aldrich syndrome suggested that transfer factor caused c...

journal_title：Annals of the New York Academy of Sciences

authors： Spitler LE

更新日期：1979-01-01 00:00:00