Micronutrient status and human immunodeficiency virus (HIV) infection.

Abstract:

:This study surveyed serum concentrations of vitamins, electrolytes, and trace elements in subjects seropositive for HIV-1 by ELISA and confirmatory Western blot. Thirty subjects (26 males, 4 females) were recruited at a hospital clinic. Seventeen were classified as having mild or severe ARC (AIDS-related complex), 7 had AIDS, and 6 were asymptomatic. Eight had experienced weight loss of 10 pounds or more in the past 6 months. Most (93%) were anergic to skin test antigens. Percentages of subjects with below normal plasma concentrations include: zinc-30%, calcium-27%, magnesium-30%, carotenes-31%, total choline-50%, and ascorbate-27%. Eighty-seven percent of the subjects had at least one abnormally low value. Percentages with above normal values include: folate-37% and carnitine-37%. Some subjects with above normal values for plasma vitamins reported self-supplementation, usually with large doses. The results suggest that one or more abnormally low concentrations of the plasma micronutrients studied here are likely to be present in the majority of HIV seropositive patients.

journal_name

Ann N Y Acad Sci

authors

Bogden JD,Baker H,Frank O,Perez G,Kemp F,Bruening K,Louria D

doi

10.1111/j.1749-6632.1990.tb00146.x

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

189-95

eissn

0077-8923

issn

1749-6632

journal_volume

587

pub_type

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