Carbon black nanoparticles promote the maturation and function of mouse bone marrow-derived dendritic cells.


:Particulate matter including carbon black (CB) nanoparticles can enhance antigen-related inflammation and immunoglobulin production in vivo. Dendritic cells (DC) as antigen-presenting cells (APC) are the most capable inducers of immune responses. The present study was designed to determine whether CB nanoparticles affect the maturation/activation and function of DC in vitro. DC were differentiated from bone marrow (BM) cells of BALB/c mice by culture with granulocyte macrophage colony stimulating factor (GM-CSF). At day 8 of culture, BM-derived DC (BMDC) were exposed to CB nanoparticles with a diameter of 14nm or 56nm for 24h. The expression of major histocompatibility complex (MHC) class II, DEC205, CD80, and CD86 (maturation/activation markers of BMDC) was measured by flow cytometry. BMDC function was evaluated by an allogeneic mixed lymphocyte reaction (MLR) assay. CB nanoparticles significantly increased the expression of DEC205 and CD86 in BMDC and tended to increase MHC class II and CD80 expression; however, a size-dependent effect was not observed. On the other hand, BMDC-mediated MLR was significantly enhanced by the CB nanoparticles and the enhancement was greater by 14nm CB nanoparticles than by 56nm CB nanoparticles. Taken together, CB nanoparticles can promote the maturation/activation and function of BMDC, which could be related to their effects on allergic diseases and/or responses. In addition, BMDC-mediated MLR might be useful assay for in vitro screening for adjuvant activity of environmental toxicants.






Koike E,Takano H,Inoue K,Yanagisawa R,Kobayashi T




Has Abstract


2008-09-01 00:00:00














  • Natural levels and photo-production rates of hydrogen peroxide (H2O2) in Andean Patagonian aquatic systems: Influence of the dissolved organic matter pool.

    abstract::In aquatic environments the reactive oxygen species hydrogen peroxide (H2O2) is produced through photochemical reactions involving chromophoric dissolved organic matter (CDOM). Andean Patagonian freshwaters experience challenging underwater UV levels, which promote high levels of photochemical weathering. In this inve...


    pub_type: 杂志文章


    authors: García PE,Queimaliños C,Diéguez MC

    更新日期:2019-02-01 00:00:00

  • Induced alkoxyresorufin-O-dealkylases in tilapias (Oreochromis niloticus) from Guandu river, Rio de Janeiro, Brazil.

    abstract::The activity of fish monooxygenases has been extensively used as a monitoring tool to detect contamination of water bodies by cytochrome P450-inducing agents. In this study we evaluated the activities of ethoxy- (EROD), methoxy- (MROD) and pentoxy- (PROD) resorufin-O-dealkylases in the liver of Nile tilapias (Oreochro...


    pub_type: 杂志文章


    authors: Parente TE,De-Oliveira AC,Silva IB,Araujo FG,Paumgartten FJ

    更新日期:2004-03-01 00:00:00

  • Management strategies for trace organic chemicals in water - A review of international approaches.

    abstract::To ensure an appropriate management of potential health risks and uncertainties from the release of trace organic chemicals (TOrCs) into the aqueous environment, many countries have evaluated and implemented strategies to manage TOrCs. The aim of this study was to evaluate existing management strategies for TOrCs in d...


    pub_type: 杂志文章,评审


    authors: Bieber S,Snyder SA,Dagnino S,Rauch-Williams T,Drewes JE

    更新日期:2018-03-01 00:00:00

  • Influence of humic acids on fungal laccase-initiated 17α-ethynylestradiol oligomerization: Transformation kinetics and products distribution.

    abstract::Fungal laccase has aroused great concern in rapidly removing estrogens because of its ability to accelerate humification and oligomerization. Here, the effect of two humic acids (HAs) on the reaction kinetics and products distribution of 17α-ethynylestradiol (EE2) in laccase-initiated humification and coupling was sys...


    pub_type: 杂志文章


    authors: Sun K,Chen H,Zhang Q,Li S,Liu Q,Si Y

    更新日期:2020-11-01 00:00:00

  • Magnetic Fe3O4-N-doped carbon sphere composite for tetracycline degradation by enhancing catalytic activity for peroxymonosulfate: A dominant non-radical mechanism.

    abstract::The design of sustainable, effective and recyclable hybrid catalysts for advanced oxidation processes is highly significant for remediation of the water environment. In this study, we synthesized magnetic Fe3O4-N-doped carbon sphere composite catalysts (Fe3O4-NCS-x) for efficient removal of tetracycline by activating ...


    pub_type: 杂志文章


    authors: Yang H,Zhou J,Yang E,Li H,Wu S,Yang W,Wang H

    更新日期:2021-01-01 00:00:00

  • Elimination kinetics and toxicity of 2,3,7,8-tetrachlorothianthren, a thio analogue of 2,3,7,8-TCDD.

    abstract::In comparison to the polychlorinated dibenzo-p-dioxins (PCDD) informations on their thio analogues the polychlorinated thianthrens (PCTA) are very limited. In this study we investigated the kinetics and toxicity of 2,3,7,8-tetrachlorothianthren (TCTA), the analogue of the most toxic PCDD congener 2,3,7,8-tetrachlorodi...


    pub_type: 杂志文章


    authors: Weber R,Hagenmaier H,Schrenk D

    更新日期:1998-05-01 00:00:00

  • Enhanced removal of Cr(VI) via in-situ synergistic reduction and fixation by polypyrrole/sugarcane bagasse composites.

    abstract::Reduction and recycling of Cr(VI) can offer environmental governance and sustainable development. Polypyrrole/sugarcane bagasse composites (PPy/SCB) for efficient adsorption and reduction of Cr(VI) in wastewater were prepared by in-situ polymerization. The effects of the initial pH, Cr concentration, adsorbent dosage,...


    pub_type: 杂志文章


    authors: Chen Z,Pan K

    更新日期:2021-01-11 00:00:00

  • Effect of ultrasonication and Fenton oxidation on biodegradation of bis(2-ethylhexyl) phthalate (DEHP) in wastewater sludge.

    abstract::The presence of bis(2-ethylhexyl) phthalate (DEHP) and its metabolites, i.e. 2-ethylhexanol, 2-ethylhexanal, and 2-ethylhexanoic acid in wastewater sludge (WWS) were investigated during aerobic digestion and Bacillus thuringiensis (Bt)-based fermentation of WWS. Ultrasonication and Fenton oxidation pre-treatment was a...


    pub_type: 杂志文章


    authors: Pham TT,Tyagi RD,Brar SK,Surampalli RY

    更新日期:2011-02-01 00:00:00

  • Detection of Dechlorane Plus and brominated flame retardants in marketed fish in Japan.

    abstract::Fish samples purchased from Japanese markets were analyzed for Dechlorane Plus (DP)(syn-, anti-), polybrominated diphenyl ether (PBDE), and hexabromocyclododecane (HBCD)(α, γ). Twenty fish were analyzed using gas chromatography-mass spectrometry for DP and PBDE, and using liquid chromatography-tandem mass spectrometry...


    pub_type: 杂志文章


    authors: Kakimoto K,Nagayoshi H,Yoshida J,Akutsu K,Konishi Y,Toriba A,Hayakawa K

    更新日期:2012-10-01 00:00:00

  • Evaluation of bacterial biodegradation and accumulation of phenanthrene in the presence of humic acid.

    abstract::This study evaluated the effect of humic acid (HA) on physicochemical properties of bacterial surfaces and on mass transfer of polycyclic aromatic hydrocarbons (PAHs) from aqueous phase into intracellular bacteria. Due to this process' potential for bacterial degradation, using Sphingobium sp. PHE3, degradation of phe...


    pub_type: 杂志文章


    authors: Xie Y,Gu Z,Herath HMSK,Gu M,He C,Wang F,Jiang X,Zhang J,Zhang Y

    更新日期:2017-10-01 00:00:00

  • Diethyl phthalate in compost: ecotoxicological effects and response of the microbial community.

    abstract::There is a great need to understand the environmental impacts of organic pollutants on soil health. Phthalates are widely used in consumables and can be found extensively. We studied the toxicity of diethyl phthalate (DEP), spiked in a compost plant growth substrate, by means of the acute toxicity Flash test and on th...


    pub_type: 杂志文章


    authors: Kapanen A,Stephen JR,Brüggemann J,Kiviranta A,White DC,Itävaara M

    更新日期:2007-05-01 00:00:00

  • A fence that eats the weed: Alginate lyase immobilization on ultrafiltration membrane for fouling mitigation and flux recovery.

    abstract::Polysaccharide fouling poses a significant challenge in the widespread application of membrane filtration for water purification. In order to mitigate the problem, a polysaccharide-degrading enzyme alginate lyase (Alg L; EC was successfully immobilized on cellulose acetate ultrafiltration membrane using a dea...


    pub_type: 杂志文章


    authors: Meshram P,Dave R,Joshi H,Dharani G,Kirubagaran R,Venugopalan VP

    更新日期:2016-12-01 00:00:00

  • Physical-chemical interactions between pharmaceuticals and biochar in synthetic and real urine.

    abstract::This research advances the knowledge of the pharmaceutical removal interactions by biochar in synthetic and real urine through the use of reference adsorbents and adsorbate probes. Earlier work has combined biochar and urine for pharmaceutical removal, however, the interactions that influence adsorption are unknown. I...


    pub_type: 杂志文章


    authors: Solanki A,Boyer TH

    更新日期:2019-03-01 00:00:00

  • Biodegradation capability of Absidia fusca Linnemann towards environmental pollutants.

    abstract::The purpose of this work was to study the bioremediation capability of Absidia fusca Linnemann (Zygomycete) towards different classes of xenobiotics (lignin-derived compounds, chloroaromatic compounds, polycyclic aromatic hydrocarbons) the presence of which in contaminated soils, water and sediments poses a significan...


    pub_type: 杂志文章


    authors: Guiraud P,Villemain D,Kadri M,Bordjiba O,Steiman R

    更新日期:2003-07-01 00:00:00

  • Bioconcentration and metabolism of ketoconazole and effects on multi-biomarkers in crucian carp (Carassius auratus).

    abstract::The tissue distribution, bioconcentration, metabolism and biological effects of the antifungal medication ketoconazole were investigated in fish, crucian carp (Carassius auratus) were exposed to a series of nominal concentrations (0.2, 2 and 20 μg/L) for 14 days. The ultra-high performance liquid chromatography tandem...


    pub_type: 杂志文章


    authors: Liu J,Lu G,Yang H,Yan Z,Wang Y,Wang P

    更新日期:2016-05-01 00:00:00

  • Comparison of the removal efficiency of endocrine disrupting compounds in pilot scale sewage treatment processes.

    abstract::The removal efficiency of endocrine disrupting compounds from effluents using pilot scale sewage treatment processes, including various treatment technologies, such as membrane bioreactors (MBR), nanofiltration (NF) and reverse osmosis (RO) for the purpose of water reuse, were estimated and compared. The calculated es...


    pub_type: 杂志文章


    authors: Lee J,Lee BC,Ra JS,Cho J,Kim IS,Chang NI,Kim HK,Kim SD

    更新日期:2008-04-01 00:00:00

  • Oryzias sinensis, a new model organism in the application of eco-toxicity and water quality criteria (WQC).

    abstract::Fish play an important role as a primary eco-toxicity test organism in environmental hazard assessment. Toxicity data of native species are often sought for use in the derivation of water quality criteria (WQC). The Chinese medaka, Oryzias sinensis, is an endemic species of China. The acute toxicity of 6 chemicals on ...


    pub_type: 杂志文章


    authors: Cui L,Fan M,Belanger S,Li J,Wang X,Fan B,Li W,Gao X,Chen J,Liu Z

    更新日期:2020-12-01 00:00:00

  • Sorption of naphthalene and 1-naphthol by biochars of orange peels with different pyrolytic temperatures.

    abstract::Biochars, derived from biomass, are increasingly recognized as an environmental-friendly sorbent to abate organic pollutants. Sorption variations of biochars with their pyrolytic temperatures are evaluated. Nine biochars of orange peels with different pyrolytic temperatures (150-700 degrees C, referred as OP150-OP700)...


    pub_type: 杂志文章


    authors: Chen B,Chen Z

    更新日期:2009-06-01 00:00:00

  • Soil-mediated prion transmission: is local soil-type a key determinant of prion disease incidence?

    abstract::Prion diseases, including chronic wasting disease (CWD) and scrapie, can be transmitted via indirect environmental routes. Animals habitually ingest soil, and results from laboratory experiments demonstrate prions can bind to a wide range of soils and soil minerals, retain the ability to replicate, and remain infectio...


    pub_type: 杂志文章,评审


    authors: Saunders SE,Bartz JC,Bartelt-Hunt SL

    更新日期:2012-05-01 00:00:00

  • On-filter degradation of particle-bound benzo[a]pyrene by ozone during air sampling: a review of the experimental evidence of an artefact.

    abstract::On-filter loss of benzo[a]pyrene (BaP) during air sampling due to reaction with ozone was observed in several experimental studies. It was also of concern in the recent CEN method for BaP measurement in ambient air: a denuder-based sampling system minimising this loss is described in the method but, due to the scarcit...


    pub_type: 杂志文章,评审


    authors: Menichini E

    更新日期:2009-11-01 00:00:00

  • Effect of halide ions on the photodegradation of ibuprofen in aqueous environments.

    abstract::Typically contained within ambient surface waters and certain industrial wastewaters, are plentiful halide ions, which possess varying degrees of photosensitivity. The effects of halide ions on the photodegradation of ibuprofen (IBP) were investigated under UV irradiation using a 500 W mercury lamp as a light source. ...


    pub_type: 杂志文章


    authors: Li F,Kong Q,Chen P,Chen M,Liu G,Lv W,Yao K

    更新日期:2017-01-01 00:00:00

  • Bioaccumulation and biomagnification of persistent organic pollutants in Indo-Pacific humpback dolphins (Sousa chinensis) from the Pearl River Estuary, China.

    abstract::Indo-Pacific humpback dolphins (Sousa chinensis) are apex predators in the Pearl River Estuary waters (PRE) of China. PCBs, DDTs and other organochlorine pesticides (OCPs) (e.g., HCHs, HCB, mirex and dieldrin) were analysed in blubber samples of 45 dolphins and 10 prey fishes of S. chinensis collected from 2004 to 201...


    pub_type: 杂志文章


    authors: Gui D,Yu R,He X,Tu Q,Chen L,Wu Y

    更新日期:2014-11-01 00:00:00

  • Heavy metal toxicity to Lemna minor: studies on the time dependence of growth inhibition and the recovery after exposure.

    abstract::Environmental concentrations of toxic substances are not necessarily constant but fluctuate over time. Periods of intense exposure might be followed by episodes with a relatively low or no exposure, in principle allowing exposed organisms to recover from toxic injury. The growth reproduction assay with the limnic vasc...


    pub_type: 杂志文章


    authors: Drost W,Matzke M,Backhaus T

    更新日期:2007-02-01 00:00:00

  • Time-dependent hormetic effects of 1-alkyl-3-methylimidazolium bromide on Vibrio qinghaiensis sp.-Q67: luminescence, redox reactants and antioxidases.

    abstract::The green credentials of ionic liquids (ILs) are being challenged due to the increasing evidence of their toxicity. The hormetic effects further raised their ecological concern. However, it remained poorly studied on the time-dependent changes of the hormetic effects and the mechanisms. In this study, we investigated ...


    pub_type: 杂志文章


    authors: Zhang J,Liu SS,Yu ZY,Zhang J

    更新日期:2013-04-01 00:00:00

  • Pyrite-assisted degradation of trichloroethene (TCE).

    abstract::Chemical kinetics of trichloroethene (TCE) degradation by pyrite was investigated at different experimental conditions. The TCE was transformed into C2H2, 1,1-dichloroethene (DCE) and C2H4 by a slow process (240 h required to convert TCE by 80%). Thereafter, the degradation rate showed a monotonous increase with the p...


    pub_type: 杂志文章


    authors: Weerasooriya R,Dharmasena B

    更新日期:2001-02-01 00:00:00

  • Investigation of acute toxicity of cadmium chloride (CdCl2 . H2O) metal salt and behavioral changes it causes on water frog (Rana ridibunda Pallas, 1771).

    abstract::The 96-h LC(50) value of cadmium chloride (CdCl(2).H(2)O), a metal salt widely used in industry, was determined in the water frog (Rana ridibunda Pallas, 1771). The experiments were conducted in two series and a total of 140 frogs were used to determine acute toxicity. In addition, behavioral changes in the water frog...


    pub_type: 杂志文章


    authors: Selvi M,Gül A,Yilmaz M

    更新日期:2003-07-01 00:00:00

  • Application of an in vivo swine model for the determination of arsenic bioavailability in contaminated vegetables.

    abstract::Considerable information is available in the literature regarding the uptake of arsenic (As) from contaminated soil and irrigation water by vegetables. However, few studies have investigated As speciation in these crops while a dearth of information is available on As bioavailability following their consumption. In th...


    pub_type: 杂志文章


    authors: Juhasz AL,Smith E,Weber J,Rees M,Rofe A,Kuchel T,Sansom L,Naidu R

    更新日期:2008-05-01 00:00:00

  • Speciation and leachability of copper in mine tailings from porphyry copper mining: influence of particle size.

    abstract::Mine tailing from the El Teniente-Codelco copper mine situated in VI Region of Chile was analysed in order to evaluate the mobility and speciation of copper in the solid material. Mine tailing was sampled after the rougher flotation circuits, and the copper content was measured to 1150 mg kg (-1) dry matter. This tail...


    pub_type: 杂志文章


    authors: Hansen HK,Yianatos JB,Ottosen LM

    更新日期:2005-09-01 00:00:00

  • Risk assessment and chemical fractionation of selected elements in surface sediments from Lake Qarun, Egypt using modified BCR technique.

    abstract::In this study, spatial distribution and chemical fractionation were conducted to appraise the overall classification of Al, B, Cd, Cr, and Pb as well as their ecological risks in Lake Qarun sediments. Also, the other chemical components (CaCO3, TOC, SO42-, SiO32-, PO43-, F, Ca, and Mg) that represented the chemical co...


    pub_type: 杂志文章


    authors: Soliman NF,El Zokm GM,Okbah MA

    更新日期:2018-01-01 00:00:00

  • Multivariate analysis of potential biomarkers of oxidative stress in Notopterus notopterus tissues from Mahanadi River as a function of concentration of heavy metals.

    abstract::In this study, investigation were done on the Mahanadi River water and health of dwelling Indian Knife fish Notopterus notopterus from three sites along the course of the river in an around Cuttack city (Odisha). Oxidative stress biomarker assays such as thiobarbituric acid reactive substances, protein carbonyls, prot...


    pub_type: 杂志文章


    authors: Mohanty D,Samanta L

    更新日期:2016-07-01 00:00:00