当前位置： SCI文献检索 > OPHTHALMOLOGY期刊下所有文献 > Prealbumin. A major constituent of vitreous amyloid.

Prealbumin. A major constituent of vitreous amyloid.

Abstract：

:Vitreous amyloid may be the presenting clinical manifestation of types 1 and 2 familial amyloidotic polyneuropathy or complicate the course of these syndromes. Recent studies have shown that the major subunit protein composing amyloid fibrils in these conditions is a variant or abnormal prealbumin molecule and that affected individuals have low levels of this protein in their blood. The authors studied material obtained at vitrectomy from two cases of vitreous amyloid. One of these was nonfamilial and the other familial. Two-dimensional gels of solubilized protein from pelleted and washed vitreous amyloid in both cases were found to consist of material with the molecular weight and isofocusing coordinates of prealbumin monomer. Reactivity of fibrils with a monospecific antiserum to prealbumin was confirmed by colloidal gold immunoelectron microscopy. Non-familial as well as familial vitreous amyloid may in fact be systemic forms of amyloidosis due to deposition of prealbumin which can be characterized by biochemical or immunohistologic studies of material obtained at vitrectomy.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Gorevic PD,Rodrigues MM,Spencer WH,Munoz PC,Allen AW Jr,Verne AZ

doi

10.1016/s0161-6420(87)33531-6

subject

Has Abstract

pub_date

1987-07-01 00:00:00

pages

792-8

issue

7

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(87)33531-6

journal_volume

94

pub_type

杂志文章

相关文献

OPHTHALMOLOGY文献大全
  • Interim FDA report on intraocular lenses.

    abstract：:Intraocular lenses have been regulated by the Food and Drug Administration since February 9, 1978. Data reported through August 9, 1979 reveal 177,503 lenses of four different classes have been implanted. The anterior chamber intraocular lens appears to have a higher incidence of certain postoperative complications co...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(80)35239-1

    authors： Worthen DM,Boucher JA,Buxton JN,Hayreh SS,Lowther G,Reinecke RD,Spencer WH,Talbott M,Weeks DF

    更新日期：1980-04-01 00:00:00

  • Phantom Eye Syndrome: Patient Experiences after Enucleation for Uveal Melanoma.

    abstract：PURPOSE:Patients undergoing enucleation for uveal melanoma need to be informed of the possibility of phantom eye syndrome (PES). The number with uveal melanoma in PES studies has been small. Aims were to: (1) determine the prevalence, symptoms, and characteristics of PES and to test associations of PES symptoms with so...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2015.04.005

    authors： Hope-Stone L,Brown SL,Heimann H,Damato B,Salmon P

    更新日期：2015-08-01 00:00:00

  • Lower eyelid recession combined with ptosis surgery in patients with poor ocular motility.

    abstract：BACKGROUND:The authors treated ten patients (13 eyelids) with visually significant blepharoptosis and compromised corneal protective mechanisms resulting from paresis of ocular motility and absent Bell phenomenon. METHODS:Traditional upper eyelid surgery consisting of frontalis suspension (6 eyelids) or levator aponeu...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(97)30356-x

    authors： Holck DE,Dutton JJ,DeBacker C

    更新日期：1997-01-01 00:00:00

  • Ophthalmic manifestations of Danon disease.

    abstract：PURPOSE:To describe the ophthalmic findings in patients with Danon disease, an X-linked condition causing cardiomyopathy in males and females. DESIGN:Retrospective case series. PARTICIPANTS:Patients with genetically proven Danon disease. METHODS:Retrospective chart review of complete eye examinations including elect...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2006.02.030

    authors： Prall FR,Drack A,Taylor M,Ku L,Olson JL,Gregory D,Mestroni L,Mandava N

    更新日期：2006-06-01 00:00:00

  • Comparison of the intraocular pressure-lowering effect of latanoprost and timolol in patients with chronic angle closure glaucoma: a preliminary study.

    abstract：OBJECTIVE:To compare the intraocular pressure (IOP)-reducing effect and side effects of 0.005% latanoprost once daily to 0.5% timolol twice daily in patients with primary chronic angle closure glaucoma (CACG). DESIGN:Randomized, double-masked two-center clinical trial. PARTICIPANTS:Thirty-two Asian patients with CACG...

    journal_title：Ophthalmology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/s0161-6420(00)00073-7

    authors： Aung T,Wong HT,Yip CC,Leong JY,Chan YH,Chew PT

    更新日期：2000-06-01 00:00:00

  • Isolated metastasis to optic nerve from medulloblastoma.

    abstract：:Isolated involvement of the optic nerve with metastatic tumor is uncommon. A 19-year-old man had a midline cerebellar medulloblastoma; a gross total removal was performed. He received postoperative radiation therapy to the whole brain, posterior fossa, and craniospinal axis. A progressive optic neuropathy developed 28...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(89)32912-5

    authors： Garrity JA,Herman DC,Dinapoli RP,Waller RR,Campbell RJ

    更新日期：1989-02-01 00:00:00

  • Risk of Systemic Adverse Events after Intravitreal Bevacizumab, Ranibizumab, and Aflibercept in Routine Clinical Practice.

    abstract：PURPOSE:Intravitreal anti-vascular endothelial growth factor (VEGF) pharmacotherapy plays a central role in the management of neovascular age-related macular degeneration (nAMD), diabetic retinal disease (DRD), and retinal venous occlusive disease (RVO). Within clinical trials, rates of systemic serious adverse events ...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2020.07.062

    authors： Maloney MH,Payne SR,Herrin J,Sangaralingham LR,Shah ND,Barkmeier AJ

    更新日期：2020-08-08 00:00:00

  • Bilateral orbital involvement in fatal giant cell polymyositis.

    abstract：:The case of a young woman with giant cell polymyositis is described. She had bilateral, severe, midly painful proptosis and ophthalmoplegia. Extensive pharyngeal, laryngeal, and cardiac muscle involvement occurred 18 months later coincident with fatal cardiac arrhythmia. At autopsy, extensive muscle necrosis and giant...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(90)32554-x

    authors： Kattah JC,Zimmerman LE,Kolsky MP,Chrousos G,Chavis R,Jaffe G,Manz HJ

    更新日期：1990-04-01 00:00:00

  • Cilioretinal artery occlusion in young adults with central retinal vein occlusion.

    abstract：:Ten patients, all younger than 50 years of age, had a temporal cilioretinal artery occlusion associated with a nonischemic central retinal vein occlusion. On fluorescein angiography, the cilioretinal artery eventually filled in all but one eye. The cilioretinal artery showed pulsations on fluorescein angiography in fi...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(91)32245-0

    authors： Schatz H,Fong AC,McDonald HR,Johnson RN,Joffe L,Wilkinson CP,de Laey JJ,Yannuzzi LA,Wendel RT,Joondeph BC

    更新日期：1991-05-01 00:00:00

  • Evaluation of the lacrimal drainage system.

    abstract：:Methods of testing for lacrimal drainage insufficiency and a modification of the Jones fluorescein dye tests are presented. Despite their excellence, Jones tests have never been widely employed because of difficulty in dye retrieval. The modification consists of instilling one drop of the dye three times at 15 second ...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(78)35559-7

    authors： Hecht SD

    更新日期：1978-12-01 00:00:00

  • Optic neuropathy after vitrectomy for retinal detachment: clinical features and analysis of risk factors.

    abstract：PURPOSE:To describe the clinical characteristics of and risk factors for the development of optic neuropathy after pars plana vitrectomy (PPV) for macula-sparing primary rhegmatogenous retinal detachment (RRD) repair. DESIGN:Retrospective case-control study. PARTICIPANTS:Seven patients who underwent PPV for macula-sp...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2012.06.002

    authors： Bansal AS,Hsu J,Garg SJ,Sivalingam A,Vander JF,Moster M,Maguire JI,Regillo CD

    更新日期：2012-11-01 00:00:00

  • Fellow eye findings of highly myopic subjects operated for retinal detachment associated with a macular hole.

    abstract：PURPOSE:To identity anatomic risk factors involved in the onset of retinal complications causing decrease of visual acuity (VA) in the fellow eyes of highly myopic patients operated for retinal detachment with macular hole (RDMH). DESIGN:Cohort study. PARTICIPANTS:Ninety-eight patients (mean age, 51.5+/-8.0 years) wi...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2008.02.016

    authors： Ripandelli G,Coppé AM,Parisi V,Stirpe M

    更新日期：2008-09-01 00:00:00

  • Mutations in MFSD8, encoding a lysosomal membrane protein, are associated with nonsyndromic autosomal recessive macular dystrophy.

    abstract：PURPOSE:This study aimed to identify the genetic defects in 2 families with autosomal recessive macular dystrophy with central cone involvement. DESIGN:Case series. PARTICIPANTS:Two families and a cohort of 244 individuals with various inherited maculopathies and cone disorders. METHODS:Genome-wide linkage analysis ...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2014.07.040

    authors： Roosing S,van den Born LI,Sangermano R,Banfi S,Koenekoop RK,Zonneveld-Vrieling MN,Klaver CC,van Lith-Verhoeven JJ,Cremers FP,den Hollander AI,Hoyng CB

    更新日期：2015-01-01 00:00:00

  • Descemet's stripping automated endothelial keratoplasty outcomes compared with penetrating keratoplasty from the Cornea Donor Study.

    abstract：PURPOSE:To assess outcomes 1 year after Descemet's stripping automated endothelial keratoplasty (DSAEK) in comparison with penetrating keratoplasty (PKP) from the Specular Microscopy Ancillary Study (SMAS) of the Cornea Donor Study. DESIGN:Multicenter, prospective, nonrandomized clinical trial. PARTICIPANTS:A total o...

    journal_title：Ophthalmology

    pub_type： 临床试验,杂志文章,多中心研究

    doi：10.1016/j.ophtha.2009.07.036

    authors： Price MO,Gorovoy M,Benetz BA,Price FW Jr,Menegay HJ,Debanne SM,Lass JH

    更新日期：2010-03-01 00:00:00

  • Ocular presentation of polyarteritis nodosa. Clinical course and management with steroid and cytotoxic therapy.

    abstract：BACKGROUND:Polyarteritis nodosa is a necrotizing vasculitis affecting medium and small-sized arteries throughout the body, including ocular tissues. Untreated polyarteritis nodosa carries a very poor prognosis. Treatment with steroids increases the 5-year survival to 48%, whereas addition of cytotoxic immunosuppressive...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(93)31405-3

    authors： Akova YA,Jabbur NS,Foster CS

    更新日期：1993-12-01 00:00:00

  • Ocular causes of abnormal head postures.

    abstract：:A prospective study was undertaken to analyze the different causes of abnormal head postures on ocular bases. Eight basic mechanisms were found in a series of 188 patients. Incomitance accounted for 62.7% of the head postures and nystagmus for 20.2%. Important diagnostic criteria for evaluating patients with head post...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(79)35301-5

    authors： Kushner BJ

    更新日期：1979-12-01 00:00:00

  • Ocular toxocariasis presenting as leukocoria in a patient with low ELISA titer to Toxocara canis.

    abstract：:A 4-year-old white female presented with leukocoria of the right eye. White punctate lesions were observed posterior to the retrolental membrane, which suggested retinoblastoma of some examiners. A full history, physical examination, ultrasonography, and CT scan failed to rule the diagnosis of retinoblastoma in or out...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(81)34860-x

    authors： Searl SS,Moazed K,Albert DM,Marcus LC

    更新日期：1981-12-01 00:00:00

  • Mechanisms of maculopathy.

    abstract：:This article will review the cellular constituents of the macula and speculate on their contribution to the pathogenesis of macular disease. The retinal pigment epithelium (RPE) has been implicated in senile macular degeneration (SMD). Over time, RPE dysfunction and death may result from the cumulative effect of light...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(84)34259-2

    authors： Eagle RC Jr

    更新日期：1984-06-01 00:00:00

  • Ocular abnormalities in abetalipoproteinemia. A clinicopathologic correlation.

    abstract：:The present paper documents the clinical characteristics and ocular pathology in a patient with abetalipoproteinemia. Noteworthy were: the predominant involvement of the posterior fundus characterized by a loss of photoreceptors; loss or attenuation of the pigment epithelium (producing a sharply demarcated white appea...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(84)34203-8

    authors： Cogan DG,Rodrigues M,Chu FC,Schaefer EJ

    更新日期：1984-08-01 00:00:00

  • Results of bilateral cataract extraction with posterior chamber intraocular lens implantation in children.

    abstract：OBJECTIVE:A retrospective study was undertaken to evaluate long-term anatomic and visual outcomes in eyes of children who underwent bilateral intraocular lens implantation. DESIGN:The study design was a review of medical records of 24 children operated on for bilateral cataracts and posterior chamber-intraocular lense...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(97)30033-5

    authors： Gimbel HV,Basti S,Ferensowicz M,DeBroff BM

    更新日期：1997-11-01 00:00:00

  • Soft lens design in aphakia.

    abstract：:Because of their size and mass, weight is a major concern in the fitting of soft gel lenses. Lenticular design is necessary, and there are essentially two lens designs for aphakia: the spin-cast lens of Bausch & Lomb and the lathe-cut lenses of the other manufacturers. A solution to the problem of weight in a single c...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(79)35500-2

    authors： Baldone JA

    更新日期：1979-03-01 00:00:00

  • Evaluation of Orbscan II corneal topography in individuals with myopia.

    abstract：PURPOSE:To evaluate Orbscan II (Bausch & Lomb, Orbtek Inc., Salt Lake City, UT) corneal topography in individuals with myopia. DESIGN:Retrospective, observational, consecutive, clinical case series. PARTICIPANTS:One hundred forty eyes of 70 persons with myopia. METHODS:Manifest refraction results and the Orbscan II ...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2005.11.004

    authors： Wei RH,Lim L,Chan WK,Tan DT

    更新日期：2006-02-01 00:00:00

  • Corneal hypesthesia and retinopathy in diabetes mellitus.

    abstract：:Testing with the Cochet-Bonnet esthesiometer revealed a strong correlation between corneal sensitivity and retinal status in a group of diabetic patients. Eyes with normal fundi had normal corneal sensitivity. Those with background retinopathy had somewhat poliferative retinopathyl showed a greater loss of sensitivity...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(80)35257-3

    authors： Rogell GD

    更新日期：1980-03-01 00:00:00

  • Subconjunctival hemorrhage and conjunctivochalasis.

    abstract：OBJECTIVE:Subconjunctival hemorrhage (SCH) is a relatively common disease, but there have been no reports concerning the relationship between SCH and conjunctivochalasis (CCh). We compared the grade of CCh between patients with SCH and control patients. DESIGN:Prospective, nonrandomized study. PARTICIPANTS:A total of...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2009.03.021

    authors： Mimura T,Usui T,Yamagami S,Funatsu H,Noma H,Honda N,Fukuoka S,Shirakawa R,Hotta H,Amano S

    更新日期：2009-10-01 00:00:00

  • Apocrine adenocarcinoma arising in Moll gland cystadenoma.

    abstract：CASE REPORT:An 85-year-old woman had a bluish tumor medially on the margin of the left upper eyelid. Malignant melanoma of the conjunctiva was presumed; the lesion was excised and submitted for routine histopathologic examination. There are no signs of recurrence or metastatic disease after follow-up for 1 year. METHO...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(93)31412-0

    authors： Seregard S

    更新日期：1993-11-01 00:00:00

  • A placebo-controlled 3-year study of a calcium blocker on visual field and ocular circulation in glaucoma with low-normal pressure.

    abstract：PURPOSE:To study the 3-year effect of oral nilvadipine, a calcium antagonist, on visual field performance and ocular circulation in open-angle glaucoma (OAG) with low-normal intraocular pressure (IOP). DESIGN:A randomized, placebo-controlled, double-masked, single-center trial. PARTICIPANTS:Patients with OAG who were...

    journal_title：Ophthalmology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ophtha.2008.05.015

    authors： Koseki N,Araie M,Tomidokoro A,Nagahara M,Hasegawa T,Tamaki Y,Yamamoto S

    更新日期：2008-11-01 00:00:00

  • Iontophoresis of fluorescein into the posterior segment of the rabbit eye.

    abstract：:Iontophoresis of appreciable quantities of fluorescein into the vitreous body of the rabbit results from the use of a high electrical current density over a limited area of the globe. This is achieved by passing current through the fluorescein when it is held against the region of the ora serrata in a tube less than 1...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(86)33781-3

    authors： Maurice DM

    更新日期：1986-01-01 00:00:00

  • Malignant nonteratoid medulloepithelioma of the ciliary body in an adult.

    abstract：BACKGROUND:The authors describe a 62-year-old man with a malignant nonteratoid malignant medulloepithelioma of the ciliary body with extension into the anterior choroid and posterior chamber. He developed gradual loss of vision in his right eye, and a clinical diagnosis of malignant melanoma of the ciliary body and cho...

    journal_title：Ophthalmology

    pub_type： 杂志文章,评审

    doi：10.1016/S0161-6420(98)94010-6

    authors： Husain SE,Husain N,Boniuk M,Font RL

    更新日期：1998-04-01 00:00:00

  • A Deep Learning Algorithm for Prediction of Age-Related Eye Disease Study Severity Scale for Age-Related Macular Degeneration from Color Fundus Photography.

    abstract：PURPOSE:Age-related macular degeneration (AMD) is a common threat to vision. While classification of disease stages is critical to understanding disease risk and progression, several systems based on color fundus photographs are known. Most of these require in-depth and time-consuming analysis of fundus images. Herein,...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2018.02.037

    authors： Grassmann F,Mengelkamp J,Brandl C,Harsch S,Zimmermann ME,Linkohr B,Peters A,Heid IM,Palm C,Weber BHF

    更新日期：2018-09-01 00:00:00

  • Management of dislocated lens fragments during phacoemulsification.

    abstract：BACKGROUND:Dislocation of nuclear lens fragments during phacoemulsification can lead to a high incidence of glaucoma, uveitis, and poor visual acuity. The correct approach to these patients is uncertain. The authors report on eight patients who underwent pars plana vitrectomy with removal of lens fragments. METHODS:Ch...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(92)31805-6

    authors： Lambrou FH Jr,Stewart MW

    更新日期：1992-08-01 00:00:00