Quantitative determination of aortic regurgitant volumes in dogs by ultrafast computed tomography.

abstract：:Coronary arteriography was performed before and after the intracoronary injection of nitroglycerin to determine the presence or absence of spasm in patients within the first 12 hours of acute myocardial infarction. Coronary arterial spasm was demonstrated in six of fifteen (40%) acute myocardial infarctions associated...

journal_title：Circulation

authors： Oliva PB,Breckinridge JC

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Chronic orthostatic intolerance (COI) is a debilitating autonomic condition in young adults. Its neurohumoral and hemodynamic profiles suggest possible alterations of postural sympathetic function and of baroreflex control of heart rate (HR). METHODS AND RESULTS:In 16 COI patients and 16 healthy volunteers,...

journal_title：Circulation

authors： Furlan R,Jacob G,Snell M,Robertson D,Porta A,Harris P,Mosqueda-Garcia R

更新日期：1998-11-17 00:00:00

abstract：:To determine the effect of calcium-channel blockers on beta-adrenergic receptors, we studied the interactions of verapamil, diltiazem, and nifedipine with both human lymphocyte beta 2-adrenergic receptors and rat myocardial beta 1-adrenergic receptors by means of radioligand binding assays. We also determined the func...

journal_title：Circulation

authors： Feldman RD,Park GD,Lai CY

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Several echocardiographic dyssynchrony indexes have been proposed to identify responders to cardiac resynchronization therapy using tissue velocity and strain. The present study aimed to compare tissue velocity-derived and strain-derived dyssynchrony indexes in patients with or without systolic dysfunction a...

journal_title：Circulation

authors： Miyazaki C,Powell BD,Bruce CJ,Espinosa RE,Redfield MM,Miller FA,Hayes DL,Cha YM,Oh JK

更新日期：2008-05-20 00:00:00

abstract：BACKGROUND:Ibutilide is an action potential-prolonging antiarrhythmic currently in clinical trials. The drug shares structural similarities with E-4031 and dofetilide, specific blockers of the rapidly activating delayed rectifier K+ current (IKr). However, previous in vitro studies in guinea pig myocytes have indicated...

journal_title：Circulation

authors： Yang T,Snyders DJ,Roden DM

更新日期：1995-03-15 00:00:00

abstract：:We examined the cardiopulmonary effects of maximum bicycle ergometer exercise in seven patients with implanted Intermedics Nova MR pacemakers for three types of pacing in a randomized sequence: VVI or AAI at 70 beats/min (SSI 70), rate-adaptive temperature-controlled pacing with the implanted Nova MR, and rate-adaptiv...

journal_title：Circulation

authors： Alt E,Völker R,Högl B,MacCarter D

更新日期：1988-11-01 00:00:00

abstract：:A new technology, leadless pacemaker therapy, was recently introduced clinically to address lead- and pocket-related complications in conventional transvenous pacemaker therapy. These leadless devices are self-contained right ventricular single-chamber pacemakers implanted by using a femoral percutaneous approach. In ...

journal_title：Circulation

authors： Tjong FV,Reddy VY

更新日期：2017-04-11 00:00:00

abstract：:Deranged magnesium concentrations in serum and cardiovascular structures have been implicated in the pathophysiology of hypertension, ischemic heart disease, arrhythmias, and sudden death. This study was conducted to determine the status and interrelation of serum and tissue concentrations of magnesium in patients wit...

journal_title：Circulation

authors： Ralston MA,Murnane MR,Kelley RE,Altschuld RA,Unverferth DV,Leier CV

更新日期：1989-09-01 00:00:00

abstract：:In patients with atrioventricular (A-V) nodal re-entrant paroxysmal supraventricular tachycardia (PSVT), atrial extrastimulus technique frequently reveals discontinuous A1-A2, H1-H2 curves suggestive of dual A-V nodal pathways. To further test the hypothesis that these curves in fact reflect dual A-V nodal pathways, a...

journal_title：Circulation

authors： Wu D,Denes P,Wyndham C,Amat-y-Leon F,Dhingra RC,Rosen KM

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:Subclinical inflammation is associated with an increased risk of heart failure and with adverse prognosis in patients with established heart failure. Yet, treatments specifically directed at reducing inflammation in patients with heart failure have not yet shown improved clinical outcomes. We tested the hypo...

journal_title：Circulation

authors： Everett BM,Cornel JH,Lainscak M,Anker SD,Abbate A,Thuren T,Libby P,Glynn RJ,Ridker PM

更新日期：2019-03-05 00:00:00

abstract：BACKGROUND:Early stages of coronary atherosclerosis are characterized by a mainly functional impairment of coronary vasodilator capacity under the impact of such risk factors as hypercholesterolemia. The goal of this study was to determine whether 6-month cholesterol-lowering therapy improves coronary flow reserve in p...

journal_title：Circulation

authors： Baller D,Notohamiprodjo G,Gleichmann U,Holzinger J,Weise R,Lehmann J

更新日期：1999-06-08 00:00:00

abstract：:The reduced responsiveness of the renin-angiotensin system to hemodynamic changes in patients with congestive heart failure (CHF) could be due to a defect of the juxtaglomerular apparatus. To test this hypothesis, the responses to viprostol, an analog of prostaglandin E2 (PGE2) that is known to stimulate both the macu...

journal_title：Circulation

authors： Olivari MT,Levine TB,Cohn JN

更新日期：1986-12-01 00:00:00

abstract：BACKGROUND:Observational studies have shown better survival in patients undergoing coronary artery bypass grafting (CABG) with 2 arterial grafts compared with 1. However, whether a third arterial graft is associated with incremental benefit remains uncertain. We sought to analyze the outcomes of 3 versus 2 arterial gra...

journal_title：Circulation

authors： Rocha RV,Tam DY,Karkhanis R,Nedadur R,Fang J,Tu JV,Gaudino M,Royse A,Fremes SE

更新日期：2018-11-06 00:00:00

abstract：BACKGROUND:Therapy with racemic compounds produces effects that can be attributed to both (S)- and (R)-enantiomers. Here we have tested the hypothesis that an enantiomer-enantiomer interaction would modulate the effects of treatment with a racemate, the antiarrhythmic propafenone. Previous studies have shown that while...

journal_title：Circulation

authors： Kroemer HK,Fromm MF,Bühl K,Terefe H,Blaschke G,Eichelbaum M

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Patients with chronic granulomatous disease (CGD) experience immunodeficiency because of defects in the phagocyte NADPH oxidase and the concomitant reduction in reactive oxygen intermediates. This may result in a reduction in atherosclerotic injury. METHODS AND RESULTS:We prospectively assessed the prevalen...

journal_title：Circulation

authors： Sibley CT,Estwick T,Zavodni A,Huang CY,Kwan AC,Soule BP,Long Priel DA,Remaley AT,Rudman Spergel AK,Turkbey EB,Kuhns DB,Holland SM,Malech HL,Zarember KA,Bluemke DA,Gallin JI

更新日期：2014-12-02 00:00:00

abstract：:We made continuous electrocardiographic recordings on magnetic tape during 15 episodes of ischemia in five patients with variant angina to determine the characteristics of the QRS changes. Orthogonal leads were used and the electrocardiograms were analyzed visually and by digital computer. Changes were quantified by s...

journal_title：Circulation

authors： Barnhill JE,Wikswo JP Jr,Dawson AK,Gundersen S,Robertson RM,Robertson D,Virmani R,Smith RF

更新日期：1985-05-01 00:00:00

abstract：:Patients with congestive heart failure have a high incidence of sudden cardiac death that is attributed to ventricular arrhythmias. The mortality rate in a group of patients with class III and IV heart failure is about 40% per year, and half of the deaths are sudden. Half of the patients with New York Heart Associatio...

journal_title：Circulation

authors： Bigger JT Jr

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Growth factors such as platelet-derived growth factor (PDGF) have been postulated to be important mediators of neointimal formation in balloon-injured artery. Binding of growth factors to their receptors activates intrinsic receptor tyrosine kinase, resulting in tyrosine phosphorylation of receptors themselv...

journal_title：Circulation

authors： Abe J,Deguchi J,Matsumoto T,Takuwa N,Noda M,Ohno M,Makuuchi M,Kurokawa K,Takuwa Y

更新日期：1997-09-16 00:00:00

abstract：BACKGROUND:Although the American Heart Association/American College of Sports Medicine's Preparticipation Questionnaire (AAPQ) is a recommended preexercise cardiovascular screening tool, it has never been systematically evaluated. The purpose of this research is to provide preliminary evidence of its effectiveness amon...

journal_title：Circulation

authors： Whitfield GP,Pettee Gabriel KK,Rahbar MH,Kohl HW 3rd

更新日期：2014-03-11 00:00:00

abstract：BACKGROUND:The safety and effectiveness of the MitraClip device (Abbott Vascular, Menlo Park, CA) is being evaluated in the Endovascular Valve Edge-to-Edge Repair Study (EVEREST) clinical studies. The healing response after device implantation has not previously been characterized in humans. METHODS AND RESULTS:A tota...

journal_title：Circulation

authors： Ladich E,Michaels MB,Jones RM,McDermott E,Coleman L,Komtebedde J,Glower D,Argenziano M,Feldman T,Nakano M,Virmani R,Endovascular Valve Edge-to-Edge Repair Study (EVEREST) Investigators.

更新日期：2011-04-05 00:00:00

abstract：BACKGROUND:Hypertrophic cardiomyopathy patients exhibit myocardial energetic impairment, but a causative role for this energy deficiency in the pathophysiology of hypertrophic cardiomyopathy remains unproven. We hypothesized that the metabolic modulator perhexiline would ameliorate myocardial energy deficiency and ther...

journal_title：Circulation

authors： Abozguia K,Elliott P,McKenna W,Phan TT,Nallur-Shivu G,Ahmed I,Maher AR,Kaur K,Taylor J,Henning A,Ashrafian H,Watkins H,Frenneaux M

更新日期：2010-10-19 00:00:00

abstract：BACKGROUND:gp130, a signal transducer of the IL-6-related cytokines, is expressed ubiquitously, including in the heart. The activation of gp130 in cardiac myocytes was reported to induce myocardial hypertrophy. The downstream side of gp130 consists of two distinct pathways in cardiac myocytes, one a Janus kinase/signal...

journal_title：Circulation

authors： Kunisada K,Tone E,Fujio Y,Matsui H,Yamauchi-Takihara K,Kishimoto T

更新日期：1998-07-28 00:00:00

abstract：:We tested the hypothesis that different subsets of ischemia-induced wall motion disorders are characterized by specific patterns of abnormal regional left ventricular systolic function. Regional contraction was quantitatively assessed from two-dimensional echocardiograms by an automated integrative analysis considerin...

journal_title：Circulation

authors： Zeiher AM,Wollschlaeger H,Bonzel T,Kasper W,Just H

更新日期：1987-10-01 00:00:00

abstract：:We assessed factors during an initial episode of ventricular fibrillation that may be predictive of recurrence. Of 141 consecutive patients with acute ischemic heart disease who survived an initial episode of ventricular fibrillation, 41 (29%) had recurrent ventricular fibrillation during hospitalization. The incidenc...

journal_title：Circulation

authors： Logan KR,McIlwaine WJ,Adgey AA,Pantridge JF

更新日期：1981-12-01 00:00:00

abstract：:Malperfusion of the thoracoabdominal aorta or its branches is a common complication of aortic dissection, often with a fatal outcome. Since 1985 we saw thoracoabdominal malperfusion in 13 patients with aortic dissection. During repair of an acute type A aortic dissection, the intimal flap was fenestrated in three case...

journal_title：Circulation

authors： Laas J,Heinemann M,Schaefers HJ,Daniel W,Borst HG

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:The FRANCE-2 registry (French Aortic National Corevalve and Edwards) previously reported good early- and medium-term clinical and echocardiographic efficacy for transcatheter aortic valve replacement. We here report 5-year follow-up results from the registry. METHODS:The registry includes all consecutive pa...

journal_title：Circulation

authors： Didier R,Eltchaninoff H,Donzeau-Gouge P,Chevreul K,Fajadet J,Leprince P,Leguerrier A,Lièvre M,Prat A,Teiger E,Lefevre T,Tchetché D,Carrié D,Himbert D,Albat B,Cribier A,Sudre A,Blanchard D,Rioufol G,Collet F,Houel

更新日期：2018-12-04 00:00:00

abstract：BACKGROUND:The purpose of this study was to assess the long-term value of dobutamine-atropine stress echocardiography (DSE) for prediction of late cardiac events in patients with proven or suspected coronary artery disease. METHODS AND RESULTS:Clinical data and DSE results were analyzed in 1734 consecutive patients un...

journal_title：Circulation

authors： Poldermans D,Fioretti PM,Boersma E,Bax JJ,Thomson IR,Roelandt JR,Simoons ML

更新日期：1999-02-16 00:00:00

abstract：BACKGROUND:Circumferential pulmonary vein ablation (CPVA) is effective in curing atrial fibrillation (AF), but new-onset left atrial tachycardia (AT) is a potential complication. We evaluated whether a modified CPVA approach including additional ablation lines on posterior wall and the mitral isthmus would reduce the i...

journal_title：Circulation

authors： Pappone C,Manguso F,Vicedomini G,Gugliotta F,Santinelli O,Ferro A,Gulletta S,Sala S,Sora N,Paglino G,Augello G,Agricola E,Zangrillo A,Alfieri O,Santinelli V

更新日期：2004-11-09 00:00:00

abstract：BACKGROUND:Vasoactive drugs could alter the fluid restitution from the tissue and redistribute blood volume between the macrocirculation and microcirculation. METHODS AND RESULTS:With bolus injections of vasoactive drugs in anesthetized rabbits, we measured the changes in blood and plasma density for the determination...

journal_title：Circulation

authors： Anderson SM,Rich GF,Roos C,Lee LP,Lee JS

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:We developed a computer model to predict lysis rates of thrombi for intravenous thrombolytic regimens based on the convective/diffusive penetration of reacting and adsorbing fibrinolytic species from the circulation into the proximal face of a dissolving clot. METHODS AND RESULTS:Solution of a one-compartme...

journal_title：Circulation

authors： Anand S,Diamond SL

更新日期：1996-08-15 00:00:00