TG and TnonG lymphocyte involvement in the proliferative response to PHA. I. Reactivity and regulatory functions of TG and TnonG subsets in the proliferative response of T lymphocytes.

Abstract:

:Both TG and TnonG subpopulations from human peripheral blood were found to secrete helper and suppressor factors for the PHA-induced T cell proliferative response. The TnonG subpopulation contained cells which were both able to secrete helper factor and to respond by proliferation, whereas in the TG subpopulation cells with a proliferative potential could not be conclusively demonstrated. Suppressor and helper activities in TG and TnonG culture supernatants displayed a different time kinetics and were influenced by the dose of mitogen in test cultures.

authors

Markowicz S,Siwicki JK,Steffen JA

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

11-21

issue

1

eissn

0004-069X

issn

1661-4917

journal_volume

35

pub_type

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