Regulatory function of normal monocytes in the in vitro immunoglobulin production.

Abstract:

:Induction of the immunoglobulin production by pokeweed mitogen (PWM) and S. aureus. Cowan I has been evaluated in cultures of human peripheral blood mononuclear cells gradually depleted of adherent cells. Partial depletion cells (monitoglobulins while almost complete depletion caused decreased production. These results suggest that an optimal balance of monocytes to lymphocytes is essential in the triggering of immunoglobulin production by human mononuclear cells (MNC) in vitro and that normal monocytes, when in excess, suppress in vitro differentiation of B lymphocytes into immunoglobulin secreting cells.

authors

Pryjma J,Miklaszewska J

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

331-6

issue

3

eissn

0004-069X

issn

1661-4917

journal_volume

29

pub_type

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