The relationship of blood lead to blood pressure in a longitudinal study of working men.

Abstract:

:The relationship of lead exposure to blood pressure has been examined in a longitudinal study of a cohort of 89 Boston, Massachusetts, policemen. At the baseline examination, subjects had a blood lead determination and three consecutive blood pressure measurements. Triplicate blood pressure measurements were also taken at years 3, 4, and 5. Multivariate analysis revealed that, after correction for previous systolic blood pressure, body mass index, age, and smoking, a high level of blood lead was a significant predictor of subsequent elevation of systolic pressure. Bootstrap simulations of these models provided supporting evidence for the observed associations. These data suggest that lead exposure can significantly affect systolic pressure.

journal_name

Am J Epidemiol

authors

Weiss ST,Muñoz A,Stein A,Sparrow D,Speizer FE

doi

10.1093/oxfordjournals.aje.a114309

subject

Has Abstract

pub_date

1986-05-01 00:00:00

pages

800-8

issue

5

eissn

0002-9262

issn

1476-6256

journal_volume

123

pub_type

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