当前位置： SCI文献检索 > JOURNAL OF HEPATOLOGY期刊下所有文献 > Chronic active hepatitis caused by benzarone.

Chronic active hepatitis caused by benzarone.

Abstract：

:We report a case of chronic active hepatitis caused by benzarone, a benzofuran derivative used in Europe for the treatment of peripheral venous disorders. Jaundice and serum alanine aminotransferase activity increased while drug administration was continued, but promptly decreased when it was eventually interrupted. Liver lesions were those of chronic active hepatitis. Anti-smooth muscle antibodies were present at a titer of 1:500 and disappeared 8 months after withdrawal of benzarone.

journal_name

J Hepatol

journal_title

Journal of hepatology

authors

Babany G,Larrey D,Pessayre D,Degott C,Rueff B,Benhamou JP

doi

10.1016/s0168-8278(87)80039-9

subject

Has Abstract

pub_date

1987-12-01 00:00:00

pages

332-5

issue

3

eissn

0168-8278

issn

1600-0641

pii

S0168-8278(87)80039-9

journal_volume

5

pub_type

杂志文章

相关文献

JOURNAL OF HEPATOLOGY文献大全
  • Prevalence of hepatocellular carcinoma in alpha-1-antitrypsin deficiency.

    abstract：:The aim of the present study was to determine the prevalence of hepatocellular carcinoma in adults with heterozygous alpha 1-antitrypsin deficiency and to assess the presence of possible co-risk factors for the development of hepatocellular carcinoma. Two hundred and forty patients with cirrhosis of different aetiolog...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/s0168-8278(05)80609-9

    authors： Propst T,Propst A,Dietze O,Judmaier G,Braunsteiner H,Vogel W

    更新日期：1994-12-01 00:00:00

  • Gα12 overexpression induced by miR-16 dysregulation contributes to liver fibrosis by promoting autophagy in hepatic stellate cells.

    abstract：BACKGROUND & AIMS:Hepatic stellate cells (HSCs) have a role in liver fibrosis. Guanine nucleotide-binding α-subunit 12 (Gα12) converges signals from G-protein-coupled receptors whose ligand levels are elevated in the environment during liver fibrosis; however, information is lacking on the effect of Gα12 on HSC trans-d...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2017.10.011

    authors： Kim KM,Han CY,Kim JY,Cho SS,Kim YS,Koo JH,Lee JM,Lim SC,Kang KW,Kim JS,Hwang SJ,Ki SH,Kim SG

    更新日期：2018-03-01 00:00:00

  • Non-invasive diagnosis of hepatocellular carcinoma ≤ 2 cm in cirrhosis. Diagnostic accuracy assessing fat, capsule and signal intensity at dynamic MRI.

    abstract：BACKGROUND & AIMS:To prospectively assess the diagnostic accuracy of the incorporation of additional magnetic resonance imaging (MRI) parameters in those based on contrast enhancement pattern for the diagnosis of solitary nodules between 5 and 20mm, detected during surveillance in patients with cirrhosis. METHODS:Betw...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2012.01.004

    authors： Rimola J,Forner A,Tremosini S,Reig M,Vilana R,Bianchi L,Rodríguez-Lope C,Solé M,Ayuso C,Bruix J

    更新日期：2012-06-01 00:00:00

  • Natural history of chronic hepatitis B in Euro-Mediterranean and African countries.

    abstract：:Data derived from population, case-control, and cohort studies conducted in several Euro-Mediterranean and African countries disclose impressive similarities in the age and modes of hepatitis B virus (HBV) transmission and in the prevalence, duration, and outcome of the four phases of the natural history of chronic in...

    journal_title：Journal of hepatology

    pub_type： 历史文章,杂志文章,评审

    doi：10.1016/j.jhep.2010.12.030

    authors： Hadziyannis SJ

    更新日期：2011-07-01 00:00:00

  • Liver stiffness accurately predicts portal hypertension related complications in patients with chronic liver disease: a prospective study.

    abstract：BACKGROUND & AIMS:The prognosis of patients with chronic liver disease is to a great extent determined by the presence and degree of portal hypertension (PHT). Hepatic venous pressure gradient (HVPG) has been shown to be an accurate prognostic index in patients with cirrhosis. Transient elastography is a non-invasive p...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2011.01.051

    authors： Robic MA,Procopet B,Métivier S,Péron JM,Selves J,Vinel JP,Bureau C

    更新日期：2011-11-01 00:00:00

  • Pattern of HCV antibodies with special reference to NS5A reactivity in HCV-infected patients: relation to viral genotype, cryoglobulinemia and response to interferon.

    abstract：BACKGROUND/AIMS:We aimed to compare the anti-hepatitis C virus reactivity in confirmatory assays (RIBA 3.0 Ortho Diagnostic and INNO-LIA HCV Ab III Innogenetics) among patients infected with different hepatitis C virus genotypes, with or without cryoglobulinemia, and in patients treated with interferon. METHODS:One hu...

    journal_title：Journal of hepatology

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0168-8278(98)80275-4

    authors： Frangeul L,Cresta P,Perrin M,Duverlie G,Khorsi H,Musset L,Opolon P,Huraux JM,Lunel F

    更新日期：1998-04-01 00:00:00

  • Role of aquaporin-4 in the development of brain oedema in liver failure.

    abstract：BACKGROUND & AIMS:Liver failure is associated with progressive cytotoxic brain oedema (astrocyte swelling), which underlies hepatic encephalopathy (HE). Ammonia and superimposed inflammation are key synergistic factors in HE, but the mechanism(s) involved remain unknown. We aimed to determine whether aquaporin-4 (AQP4)...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2010.02.020

    authors： Wright G,Soper R,Brooks HF,Stadlbauer V,Vairappan B,Davies NA,Andreola F,Hodges S,Moss RF,Davies DC,Jalan R

    更新日期：2010-07-01 00:00:00

  • Safety and efficacy of in vitro fertilisation in patients with chronic liver disease and liver transplantation recipients.

    abstract：BACKGROUND:Chronic liver disease and liver transplantation (LT) can delay both timing and ability of women to conceive. With increased awareness and availability of in vitro fertilisation (IVF), the need for accurate counselling is paramount. To date, minimal data exists to inform outcomes of IVF in patients with chron...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2020.12.022

    authors： Rahim MN,Theocharidou E,Yen Lau KG,Ahmed R,Marattukalam F,Long L,Cannon MD,Heneghan MA

    更新日期：2021-01-15 00:00:00

  • Regulation of organic anion transporters in a new rat model of acute and chronic cholangitis resembling human primary sclerosing cholangitis.

    abstract：BACKGROUND/AIMS:Primary sclerosing cholangitis (PSC) is a cholestatic liver disease of unknown etiology. Although the primary defect affects cholangiocytes, cholestatic injury of hepatocytes may promote further liver damage. Since down-regulation of hepatocellular organic anion transporters is implicated in the molecul...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/s0168-8278(02)00052-1

    authors： Geier A,Dietrich CG,Lammert F,Orth T,Mayet WJ,Matern S,Gartung C

    更新日期：2002-06-01 00:00:00

  • Hepatic endothelial dysfunction and abnormal angiogenesis: new targets in the treatment of portal hypertension.

    abstract：:Portal hypertension is the main cause of complications in patients with chronic liver disease. Over the past 25 years, progress in the understanding of the pathophysiology of portal hypertension was followed by the introduction of an effective pharmacological therapy, consisting mainly of treatments aimed at correctin...

    journal_title：Journal of hepatology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jhep.2010.03.021

    authors： Bosch J,Abraldes JG,Fernández M,García-Pagán JC

    更新日期：2010-09-01 00:00:00

  • Menopausal age and sex hormones in postmenopausal women with alcoholic and non-alcoholic liver disease.

    abstract：:In order to evaluate age at menopause and serum sex hormone profiles in postmenopausal women with stable chronic liver disease, six non-cirrhotic alcoholics, 13 with alcoholic cirrhosis, eight with non-alcoholic cirrhosis, and 46 healthy controls were studied. In all three groups, patients were significantly (p less t...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/0168-8278(91)90859-a

    authors： Becker U,Gluud C,Farholt S,Bennett P,Micic S,Svenstrup B,Hardt F

    更新日期：1991-07-01 00:00:00

  • Pathogenesis of lipid metabolism disorder in hepatitis C: polyunsaturated fatty acids counteract lipid alterations induced by the core protein.

    abstract：BACKGROUND & AIMS:Disturbance in lipid metabolism is one of the features of chronic hepatitis C, being a crucial determinant of the progression of liver fibrosis. Experimental studies have revealed that the core protein of hepatitis C virus (HCV) induces steatosis. METHODS:The activities of fatty acid metabolizing enz...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2010.07.039

    authors： Miyoshi H,Moriya K,Tsutsumi T,Shinzawa S,Fujie H,Shintani Y,Fujinaga H,Goto K,Todoroki T,Suzuki T,Miyamura T,Matsuura Y,Yotsuyanagi H,Koike K

    更新日期：2011-03-01 00:00:00

  • Stress management: How the unfolded protein response impacts fatty liver disease.

    abstract：:Induction of the unfolded protein response (UPR) is recognized as central to fatty liver disease (FLD) pathophysiology. This pathway may be a potential therapeutic target for FLD, as well as other diseases. However, fundamental questions as to how UPR contributes to FLD remain unanswered. Conflicting data suggest that...

    journal_title：Journal of hepatology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jhep.2012.06.018

    authors： Imrie D,Sadler KC

    更新日期：2012-11-01 00:00:00

  • Effect of androgens and their manipulation on cell growth and androgen receptor (AR) levels in AR-positive and -negative human hepatocellular carcinomas.

    abstract：BACKGROUND/AIMS:Little is known about genuine roles of androgens and their receptor in hepatocellular carcinoma. METHODS:In the present study, two sublines derived from a human hepatocellular carcinoma cell line KYN-1 were used: KYN-1/SM10 with androgen receptor and KYN-1/SM2 without androgen receptor. RESULTS:The bi...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/0168-8278(95)80282-7

    authors： Yu L,Nagasue N,Makino Y,Nakamura T

    更新日期：1995-03-01 00:00:00

  • Safety of the 2D/3D direct-acting antiviral regimen in HCV-induced Child-Pugh A cirrhosis - A pooled analysis.

    abstract：BACKGROUND & AIMS:Chronic hepatitis C virus (HCV)-infected patients with cirrhosis are a high-priority population for treatment. To help inform the benefit-risk profile of the all-oral direct-acting antiviral (DAA) combination regimen of ombitasvir, paritaprevir, and ritonavir, with or without dasabuvir (OBV/PTV/r±DSV)...

    journal_title：Journal of hepatology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jhep.2017.06.011

    authors： Poordad F,Nelson DR,Feld JJ,Fried MW,Wedemeyer H,Larsen L,Cohen DE,Cohen E,Mobashery N,Tatsch F,Foster GR

    更新日期：2017-10-01 00:00:00

  • A controlled trial of prednisolone treatment in primary biliary cirrhosis. Three-year results.

    abstract：:The results of a 3-year, placebo-controlled trial of prednisolone treatment in primary biliary cirrhosis (PBC) are presented. The active (n = 19) and placebo (n = 17) arms were initially well matched for age, menopausal status and disease severity. At 3 years hepatic symptoms were relatively improved in the prednisolo...

    journal_title：Journal of hepatology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0168-8278(92)90065-w

    authors： Mitchison HC,Palmer JM,Bassendine MF,Watson AJ,Record CO,James OF

    更新日期：1992-07-01 00:00:00

  • The bidirectional impacts of alcohol consumption and the metabolic syndrome: Cofactors for progressive fatty liver disease.

    abstract：:Current medical practice artificially dichotomises a diagnosis of fatty liver disease into one of two common forms: alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD). Together, these account for the majority of chronic liver diseases worldwide. In recent years, there has been a dramatic incre...

    journal_title：Journal of hepatology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jhep.2017.11.006

    authors： Boyle M,Masson S,Anstee QM

    更新日期：2018-02-01 00:00:00

  • Modulation of fibronectin gene expression in inflammatory mononuclear phagocytes of rat liver after acute liver injury.

    abstract：BACKGROUND/AIMS:In acute liver injury, fibronectin (FN) is deposited at the site of hepatocellular necrosis. We have previously shown that liver inflammatory mononuclear phagocytes (MNP), in contrast to quiescent hepatic macrophages, synthesize abundant amounts of FN. We now analyzed effects of agents known to influenc...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2003.12.013

    authors： Armbrust T,Kreissig M,Tron K,Ramadori G

    更新日期：2004-04-01 00:00:00

  • Cost-effectiveness of semi-annual surveillance for hepatocellular carcinoma in cirrhotic patients of the Italian Liver Cancer population.

    abstract：BACKGROUND & AIMS:It was recently shown that semi-annual surveillance for hepatocellular carcinoma (HCC) in cirrhotic patients provides a prognostic advantage over the annual program; however, its cost-effectiveness (CE) in the general cirrhotic population still needs to be defined. METHODS:A Markov model was built to...

    journal_title：Journal of hepatology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jhep.2011.11.022

    authors： Cucchetti A,Trevisani F,Cescon M,Ercolani G,Farinati F,Poggio PD,Rapaccini G,Nolfo MAD,Benvegnù L,Zoli M,Borzio F,Giannini EG,Caturelli E,Chiaramonte M,Pinna AD,Italian Liver Cancer (ITA.LI.CA) Group.

    更新日期：2012-05-01 00:00:00

  • Production of abnormal prothrombin (des-gamma-carboxy prothrombin) by hepatocellular carcinoma. A clinical and experimental study.

    abstract：:We measured plasma abnormal prothrombin (des-gamma-carboxy prothrombin; DCP) levels in normal subjects and in patients with hepatocellular carcinoma and other various diseases using the enzyme-linked immunosorbent assay developed by Motohara et al. (Pediatr Res 1985; 19: 354-357). Fifty-eight percent of 52 patients wi...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/s0168-8278(87)80546-9

    authors： Okuda H,Obata H,Nakanishi T,Furukawa R,Hashimoto E

    更新日期：1987-06-01 00:00:00

  • Effect of vascular endothelial growth factor on hepatic regenerative activity following partial hepatectomy in rats.

    abstract：BACKGROUND/AIMS:Vascular endothelial growth factor (VEGF) is an angiogenic factor with a growth-promoting effect that is thought to be restricted to vascular endothelial cells. Its essential role during liver regeneration has yet to be determined. The aim of this study was to document the effect of exogenous VEGF admin...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/s0168-8278(99)80147-0

    authors： Assy N,Spira G,Paizi M,Shenkar L,Kraizer Y,Cohen T,Neufeld G,Dabbah B,Enat R,Baruch Y

    更新日期：1999-05-01 00:00:00

  • The hepatitis B virus and the host response.

    abstract：:The clearance of hepatitis B virus infected cells from the liver is probably dependent on an interplay between the interferon system and the cellular limb of the host immune response. Although the importance of the nucleocapsid proteins as targets for sensitized cytotoxic T cells is established in chronic hepatitis B ...

    journal_title：Journal of hepatology

    pub_type： 杂志文章,评审

    doi：10.1016/0168-8278(90)90170-v

    authors： Thomas HC

    更新日期：1990-01-01 00:00:00

  • Time profile of the haemodynamic effects of terlipressin in portal hypertension.

    abstract：BACKGROUND/AIMS:Terlipressin is a long-acting vasopressin analogue that has been proved useful in the treatment of variceal haemorrhage. This study investigates the time profile of the haemodynamic effects of terlipressin on portal hypertension as well as the efficacy in decreasing portal-pressure and collateral blood ...

    journal_title：Journal of hepatology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0168-8278(97)80428-x

    authors： Escorsell A,Bandi JC,Moitinho E,Feu F,García-Pagan JC,Bosch J,Rodés J

    更新日期：1997-03-01 00:00:00

  • Human leukocyte antigen-G (HLA-G) expression in biliary epithelial cells is associated with allograft acceptance in liver-kidney transplantation.

    abstract：BACKGROUND/AIMS:Liver allograft is known to protect simultaneously transplanted organs from acute rejection. We have reported that only 6% of combined liver-kidney recipients, versus 32.5% of kidney recipients, develop kidney graft acute rejection. Release of soluble human leukocyte antigen (HLA) molecules by the liver...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/s0168-8278(03)00354-4

    authors： Créput C,Durrbach A,Menier C,Guettier C,Samuel D,Dausset J,Charpentier B,Carosella ED,Rouas-Freiss N

    更新日期：2003-10-01 00:00:00

  • Acyclic retinoid induces partial differentiation, down-regulates telomerase reverse transcriptase mRNA expression and telomerase activity, and induces apoptosis in human hepatoma-derived cell lines.

    abstract：BACKGROUND/AIMS:Acyclic retinoid (AR; all trans-3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid) prevented hepatocarcinogenesis in animal models and in a randomized clinical trial by eradicating premalignant and latent malignant clones of transformed cells from the liver. We investigated the possible mechanis...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/s0168-8278(02)00044-2

    authors： Yasuda I,Shiratori Y,Adachi S,Obora A,Takemura M,Okuno M,Shidoji Y,Seishima M,Muto Y,Moriwaki H

    更新日期：2002-05-01 00:00:00

  • Hepatocellular ballooning in NASH.

    abstract：BACKGROUND & AIMS:Hepatocellular ballooning is a key finding in nonalcoholic steatohepatitis (NASH). It is conventionally defined by hemotoxylin and eosin (H&E) staining showing enlarged cells with rarefied cytoplasm and recently by changes in the cytoskeleton. Fat droplets are emerging as important organelles in cell ...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2010.04.031

    authors： Caldwell S,Ikura Y,Dias D,Isomoto K,Yabu A,Moskaluk C,Pramoonjago P,Simmons W,Scruggs H,Rosenbaum N,Wilkinson T,Toms P,Argo CK,Al-Osaimi AM,Redick JA

    更新日期：2010-10-01 00:00:00

  • Unsaturated fatty acids promote hepatoma proliferation and progression through downregulation of the tumor suppressor PTEN.

    abstract：BACKGROUND/AIMS:The impact of dietary fatty acids on the development of cancers is highly controversial. We recently demonstrated that unsaturated fatty acids trigger the downregulation of the tumor suppressor PTEN through an mTOR/NF-kappaB-dependent mechanism in hepatocytes. In this study, we investigated whether unsa...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2009.01.027

    authors： Vinciguerra M,Carrozzino F,Peyrou M,Carlone S,Montesano R,Benelli R,Foti M

    更新日期：2009-06-01 00:00:00

  • Controlled HIV viral replication, not liver disease severity associated with low bone mineral density in HIV/HCV co-infection.

    abstract：BACKGROUND & AIMS:To evaluate the prevalence and risk factors for low bone mineral density (BMD) in persons co-infected with HIV and Hepatitis C. METHODS:HIV/HCV co-infected study participants (n=179) were recruited into a prospective cohort and underwent dual-energy X-ray absorptiometry (DXA) within 1 year of a liver...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2011.01.035

    authors： El-Maouche D,Mehta SH,Sutcliffe C,Higgins Y,Torbenson MS,Moore RD,Thomas DL,Sulkowski MS,Brown TT

    更新日期：2011-10-01 00:00:00

  • Different turnover rate of hepatitis C virus clearance by different treatment regimen using interferon-beta.

    abstract：BACKGROUND/AIM:Since patients with high viral load and HCV subtype 1b are known to respond poorly to interferon (IFN) therapy, the viral dynamics of HCV RNA after initiation of interferon therapy were examined in the present study with respect to two different administration regimens, once vs. twice a day. METHODS:Twe...

    journal_title：Journal of hepatology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0168-8278(00)80373-6

    authors： Shiratori Y,Perelson AS,Weinberger L,Imazeki F,Yokosuka O,Nakata R,Ihori M,Hirota K,Ono N,Kuroda H,Motojima T,Nishigaki M,Omata M

    更新日期：2000-08-01 00:00:00

  • Hepatocellular proliferation in patients with chronic hepatitis C and persistently normal or abnormal aminotransferase levels.

    abstract：BACKGROUND/AIMS:Some patients chronically infected with the hepatitis C virus (HCV) have persistently normal alanine aminotransferase (ALT) levels while progressive liver damage is observed histologically. In the present study, we compared the rate of proliferation, apoptosis, and necrosis in liver biopsy specimens of ...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1034/j.1600-0641.2000.033004640.x

    authors： Kronenberger B,Rüster B,Lee JH,Sarrazin C,Roth WK,Herrmann G,Zeuzem S

    更新日期：2000-10-01 00:00:00