Abstract:
:Auscultation was compared to two-dimensional echocardiography (2D echo) and Doppler ultrasonography in 140 consecutive patients referred for evaluation for suspected mitral valve prolapse (MVP) to asses the precision of the two diagnostic methods. Ninety patients (64%) had midsystolic clicks, of which 42 (47%) had MVP by echocardiography; 6 patients (4%) had MVP by 2D echo but no click on examination. In 15 (17%) of the 90 patients, a click was heard only in the standing or squatting positions and 2D echo did not detect prolapse in the supine position in 10 (67%) of the 15. With auscultation as the reference standard for MVP, 2D echo has a sensitivity of 47% and a specificity of 89%. Of the 140 patients, 51 (36%) had systolic murmurs; Doppler detected mitral and/or tricuspid regurgitation in 26 (50%). In 23 (16%) patients, there was Doppler evidence of mitral or tricuspid regurgitation even though systolic murmurs were not heard. Auscultation shows a 53% sensitivity and 73% specificity for systolic murmurs, using Doppler ultrasonography as the reference standard. Of 48 patients with MVP by 2D echo, 15 (13%) had associated mitral regurgitation by Doppler. The results indicate that 2D echo and Doppler ultrasonography should be interpreted in concert with auscultation for the diagnosis of mitral valve prolapse and for therapeutic decision making.
journal_name
Clin Cardioljournal_title
Clinical cardiologyauthors
Barron JT,Manrose DL,Liebson PRdoi
10.1002/clc.4960110608subject
Has Abstractpub_date
1988-06-01 00:00:00pages
401-6issue
6eissn
0160-9289issn
1932-8737journal_volume
11pub_type
杂志文章abstract::The designation of atherosclerosis as a chronic inflammatory process represents an exciting and logical paradigm shift for cardiologists. Monocyte chemoattractant protein-1 (MCP-1) plays an important role in the recruitment and activation of monocytes and thus in the development of atherosclerosis. Enhanced MCP-1 expr...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960250403
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:The objective of this study was to estimate the prevalence of prehypertension and hypertension in the rural adults of Liaoning province of China. METHODS:The study was conducted in 2004-2006, using a multistage cluster sampling method to select a representative sample. A total of 45925 adults, 35 years or o...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20073
更新日期:2007-04-01 00:00:00
abstract::Many invasive and noninvasive methods have been used to study the cardiac atria; however, few allow quantitative measurement of atrial function. To determine the interaction between left ventricular (LV) contraction and left atrial (LA) filling, gated radionuclide angiography was conducted in 30 normal subjects (24 me...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960170508
更新日期:1994-05-01 00:00:00
abstract::Hypertrophic cardiomyopathy predisposes patients to atrial fibrillation and the development of systemic embolization. We describe a rare case of bilateral renal artery thrombosis which presented as acute renal failure requiring dialysis. The patient was successfully treated with a selective, continuous infusion of uro...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960171114
更新日期:1994-11-01 00:00:00
abstract::Two cases with acute myocardial infarction are presented. Both had thrombotic occlusion of the infarct-related artery. Following successful thrombolysis with streptokinase, coronary angiography was normal. These cases prove that "myocardial infarction with normal coronaries" can be associated with coronary thrombosis ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960061107
更新日期:1983-11-01 00:00:00
abstract::The aim of this study was to assess whether drinking social amounts of alcohol impairs myocardial contractility in normal humans. To that end, 17 healthy volunteers performed isometric handgrip exercise before and 60 minutes after an intake of 1 g/kg body weight of ethanol within 60 minutes. Left ventricular M-mode ec...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960060302
更新日期:1983-03-01 00:00:00
abstract::This report describes a patient who developed acute severe exacerbation of mild rheumatic mitral regurgitation caused by ischemia in the territory of a small, non-dominant circumflex coronary artery without myocardial infarction. ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960151215
更新日期:1992-12-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to examine the influence of atrial fibrillation (AF) on the immediate and long-term outcome of patients undergoing balloon mitral valvotomy (BMV). HYPOTHESIS:Patients with atrial fibrillation fair poorly after balloon mitral valvotomy. METHODS:There were a total of 818 consecu...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22068
更新日期:2012-12-01 00:00:00
abstract::Transient left ventricular (LV) apical ballooning and normal epicardial coronary arteries are the hallmarks of Takotsubo cardiomyopathy. The syndrome is often triggered by emotional or physiologic stress, and its pathogenesis is poorly understood. Current proposals focus on elevated cathecolamines in association with ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20065
更新日期:2007-07-01 00:00:00
abstract::To assess the immediate and long-term effects of exercise on factors regulating blood flow, we measured plasma viscosity (eta p) and plasma renin activity (PRA) in 17 trained runners and 16 sedentary healthy subjects before and 10 min after graded treadmill exercise. Resting eta p was lower in runners primarily becaus...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960040405
更新日期:1981-07-01 00:00:00
abstract::Signal-averaged electrocardiograms were obtained in 53 consecutive patients with a first acute myocardial infarction (AMI) who survived the first 10 days of hospitalization. The recording was performed twice, at Day 1 and at Day 10 of hospitalization, in patients without bundle-branch block and who did not receive ant...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960131005
更新日期:1990-10-01 00:00:00
abstract::This report describes the development of a quality assurance-oriented integrated software system designed for an anesthesiology-based intraoperative transesophageal echocardiography service. Entry data include patient and operation demographics, two-dimensional echocardiographic, saline-contrast, and color flow/pulsed...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960161012
更新日期:1993-10-01 00:00:00
abstract:BACKGROUND:The global T-inversion (GTI) electrocardiogram (ECG) is strikingly abnormal with major QTc prolongation, but with a surprisingly good prognosis by Kaplan-Meier curve. This contrasts with most significant QTc prolongations. HYPOTHESIS:This study was undertaken to ascertain QT interval dispersion (QTd) in glo...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960221012
更新日期:1999-10-01 00:00:00
abstract::The effect of intravenous bepridil, a new calcium antagonist with class I and III properties, was tested in 21 patients with sustained ventricular tachyarrhythmias refractory to a mean of five antiarrhythmic agents as assessed by programmed right ventricular stimulation. At control electrophysiologic study without ant...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960131209
更新日期:1990-12-01 00:00:00
abstract::The hemodynamic and myocardial energetic changes due to pulsus alternans were investigated by left and right heart catheterization and by oxygen consumption measurements in three patients with dilative cardiomyopathy. In all three patients, pulsus alternans developed after intravenous administration of the phosphodies...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960100506
更新日期:1987-05-01 00:00:00
abstract:BACKGROUND:Recently, several treadmill scores have been proposed as means for improving the diagnostic accuracy of the exercise treadmill test (ETT). Questions remain regarding the diagnostic accuracy of treadmill scores when applied to a different patient population than that from which they were derived; furthermore,...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960250307
更新日期:2002-03-01 00:00:00
abstract:BACKGROUND:Therapeutic hypothermia improves survival for selected patients who remain comatose after cardiac arrest. Hypothermia triggers changes in electrocardiographic (ECG) parameters; however, the association of these changes to in-hospital mortality remains unclear. HYPOTHESIS:QT interval changes induced by thera...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22224
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:It is known that exercise-induced ST-segment elevation in lead V1 (V1-E) detects left anterior descending (LAD) stenosis. It was also postulated that ST elevation in aVR and simultaneous ST depression in V5 (aVR-E + V5-D) is a marker of ischemia due to significant stenosis of the LAD in patients with single-...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960260506
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:The electrocardiogram (ECG) is valuable for the identification of prior myocardial infarction (MI) in individuals participating in epidemiologic studies or undergoing screening examinations. Although the Minnesota Code, a set of criteria for the interpretation of ECGs in such situations, is commonly used to ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960270212
更新日期:2004-02-01 00:00:00
abstract::In order to assess the diagnostic value of dipyridamole (D) testing, we studied the responses of 34 patients with chest pain and 10 normal subjects. Blood pressure and 12-lead ECG were recorded during and after intravenous infusion of 0.6 mg/kg dipyridamole for 10 minutes. Coronary arteriography and maximal or symptom...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960050402
更新日期:1982-04-01 00:00:00
abstract::Cardiovascular risk factors are known to be associated with the presence of erectile dysfunction (ED), and ED is more common in men with cardiovascular disease (CVD). The Princeton Guidelines provide a strategy for assessing cardiac risk and planning a safe return to sexual activity. Men at low risk, who have fewer th...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960271304
更新日期:2004-04-01 00:00:00
abstract::Angioplasty in patients with unstable coronary artery disease is associated with higher complication rates compared with patients with stable disease. In this report we describe our results from a group of patients with unstable disease (unstable angina pectoris and postmyocardial infarction) where a strategy of delay...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960190208
更新日期:1996-02-01 00:00:00
abstract:BACKGROUND:While depressed left ventricular ejection fraction is clearly associated with poor long-term outcome in heart failure (HF), the effect of ejection fraction on short-term outcomes and resource utilization following hospitalization for HF remains unclear. HYPOTHESIS:We evaluated the independent effect of depr...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960220306
更新日期:1999-03-01 00:00:00
abstract::The pseudoaneurysm is a rare cardiac pathology, in which the left ventricular free wall ruptures and the pericardium surrounds the rupture in combination with thrombus and inflammation and thus prevents the development of a hemopericardium. Left ventricular pseudoaneurysm may remain silent unless it gives rise to card...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20311
更新日期:2009-06-01 00:00:00
abstract::Arrhythmogenic right ventricular dysplasia (ARVD) is a rare cardiomyopathy characterized by the progressive replacement of cardiomyocytes by fatty and fibrous tissue in the right ventricle (RV). These infiltrations lead to cardiac electrical instability and ventricular arrhythmia. Current treatment for ARVD is empiric...
journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/clc.22884
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Current National Cholesterol Education Program (NCEP) guidelines recognize low-density lipoprotein cholesterol (LDL-C) below 100 mg/dl as an optimal level. Evidence supporting this is scant. Both LDL-C and C reactive protein (CRP) are known correlates of atherosclerosis progression. HYPOTHESIS:We examined t...
journal_title:Clinical cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/clc.4960270105
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Hypercholesterolemia is a risk factor for coronary artery disease, yet is associated with lower risk of adverse outcomes in patients with acute coronary syndromes (ACS). HYPOTHESIS:We explored this paradox in 84,429 patients with non-ST-segment elevation ACS in the Can Rapid Risk Stratification of Unstable ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20518
更新日期:2009-09-01 00:00:00
abstract::It has been debated whether dilated cardiomyopathy seen in patients with acquired immune deficiency syndrome is caused by the virus itself or by the combination of other factors such as presence of opportunistic pathogens and/or severe immunosuppression. This paper describes the first reported case of a patient with h...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960200815
更新日期:1997-08-01 00:00:00
abstract:BACKGROUND:Epicardial placement of the left ventricular (LV) lead via a video-assisted thoracoscopic (VAT) approach is an alternative to the standard transvenous technique. HYPOTHESIS:Long-term safety and efficacy of VAT and transvenous LV lead implantation are comparable. To test it, we reviewed our experience and we...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.23300
更新日期:2020-03-01 00:00:00
abstract::High dose-dobutamine (DOB) has been previously used as a pharmacological stress test to evaluate wall motion abnormalities. As a result, recent stress echocardiography with low-dose DOB has been reported to be valuable for investigating stunned myocardium after thrombolysis. However, echocardiography requires an opera...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960160604
更新日期:1993-06-01 00:00:00