Effect of left ventricular contractile performance on passive left atrial filling--clinical study using radionuclide angiography.

Abstract:

:Many invasive and noninvasive methods have been used to study the cardiac atria; however, few allow quantitative measurement of atrial function. To determine the interaction between left ventricular (LV) contraction and left atrial (LA) filling, gated radionuclide angiography was conducted in 30 normal subjects (24 men and 6 women, mean age 58 +/- 10 years, range 26-68). LV and LA time-activity curves and their first-derivative curves were obtained simultaneously by using the method of Bough et al. The LV ejection fraction (64 +/- 18%) and LV peak ejection rate (LVPER; 3.42 +/- 0.27 EDV/s) were computed from these curves. As indices of LA filling, LA fractional emptying (38 +/- 12%) and LA peak filling rate (LAPFR; 2.86 +/- 0.17 LAVmax/s)--the latter being defined as the peak rate of LA filling during the LA filling phase--were also computed from these curves. In all subjects, the timing of the LVPER coincided with the occurrence of LAPFR, and there was a significant positive correlation between the LVPER and LAPFR (r = 0.81, p < 0.001), indicating that the LAPFR was strongly affected by the degree of LVPER. Thus, these results indicate that LV contractile performance plays an important role in determining LA passive filling during ventricular systole.

journal_name

Clin Cardiol

journal_title

Clinical cardiology

authors

Fujii K,Ozaki M,Yamagishi T,Ishine K,Furutani Y,Nagano H,Yamamoto K,Saiki A,Matsuzaki M

doi

10.1002/clc.4960170508

subject

Has Abstract

pub_date

1994-05-01 00:00:00

pages

258-62

issue

5

eissn

0160-9289

issn

1932-8737

journal_volume

17

pub_type

杂志文章
  • Percutaneous coronary interventions in nonagenarians: in-hospital mortality and outcome at one year follow-up.

    abstract:BACKGROUND:Limited information is available regarding outcome of very elderly patients referred for percutaneous coronary intervention (PCI). PURPOSE:This study aimed to assess acute and intermediate term clinical outcomes among nonagenarians. METHODS:The study included 32 consecutive nonagenarian patients undergoing...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20596

    authors: Parikh R,Chennareddy S,Debari V,Hamdan A,Konlian D,Shamoon F,Bikkina M

    更新日期:2009-12-01 00:00:00

  • Hyponatremia in acute decompensated heart failure: mechanisms, prognosis, and treatment options.

    abstract::Hyponatremia is common and is increasingly recognized as an independent prognostic marker that adversely affects morbidity and mortality in various disease states, including heart failure. In acute decompensated heart failure (ADHF), the degree of hyponatremia often parallels the severity of cardiac dysfunction and is...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.20822

    authors: Jao GT,Chiong JR

    更新日期:2010-11-01 00:00:00

  • Assessment of Respiratory Distress by the Roth Score.

    abstract:INTRODUCTION:Health care demand is increasing due to greater longevity of patients with chronic comorbidities. This increasing demand is occurring in a setting of resource scarcity. To address these changes, high-value care initiatives, such as telemedicine, are valuable resource-preservation strategies. This study int...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22586

    authors: Chorin E,Padegimas A,Havakuk O,Birati EY,Shacham Y,Milman A,Topaz G,Flint N,Keren G,Rogowski O

    更新日期:2016-11-01 00:00:00

  • Cardiac troponin I predicts clinical outcome of patients with cancer at emergency department.

    abstract:BACKGROUND:The prognostic ability of cardiac troponin I (TnI) has been demonstrated in general populations and among cardiovascular disease patients, but it has not been evaluated in cancer patients. HYPOTHESIS:This study assumes to have the prognostic ability of cardiac troponin in cancer patients visiting the emerge...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.23486

    authors: Park SH,Kim T,Cha WC,Yoon H,Hwang SY,Shin TG,Sim MS,Jo I,Lee SH,Park HD,Choi JH

    更新日期:2020-12-01 00:00:00

  • Study of lipoprotein(a) and its impact on atherosclerotic cardiovascular disease: Design and rationale of the Mass General Brigham Lp(a) Registry.

    abstract::Lipoprotein(a) [Lp(a)] is independently associated with atherosclerotic cardiovascular disease and calcific aortic valve stenosis. Elevated Lp(a) affects approximately one in five individuals and meaningfully contributes to the residual cardiovascular risk in individuals with otherwise well-controlled risk factors. Wi...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.23456

    authors: Berman AN,Biery DW,Ginder C,Hulme OL,Marcusa D,Leiva O,Wu WY,Singh A,Divakaran S,Hainer J,Turchin A,Januzzi JL,Natarajan P,Cannon CP,Di Carli MF,Bhatt DL,Blankstein R

    更新日期:2020-11-01 00:00:00

  • Influence of angiotensin-converting enzyme gene polymorphism on development of athlete's heart.

    abstract:BACKGROUND AND HYPOTHESIS:Genetic influence on development of athlete's heart is uncertain. This study investigated whether angiotensin-converting enzyme (ACE) gene polymorphism influenced development of athlete's heart. METHODS:Forty-three participants in a 100-km ultramarathon were classified on the basis of ACE gen...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960230814

    authors: Nagashima J,Musha H,Takada H,Awaya T,Oba H,Mori N,Ohmiya K,Nobuoka S,Murayama M

    更新日期:2000-08-01 00:00:00

  • Influence of risk factors on long-term survival following acute myocardial infarction: a follow-up study in central Japan.

    abstract::The long-term survival rate following acute myocardial infarction (AMI) was studied in 358 patients in central Japan who were monitored for 8 to 20 years after discharge from hospital for AMI. Fifteen-year cardiac survival rates were 65% in males and 72% in females. In both sexes, the survival rate decreased with incr...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960120905

    authors: Enomoto N,Yamauchi K,Hayashi H,Saito H,Hamajima N,Sasaki R,Sotobata I,Tanimura H

    更新日期:1989-09-01 00:00:00

  • Prolonged low-dose thrombolytic therapy: a novel adjunctive strategy in the management of an infected right atrial thrombus.

    abstract::An 81-year-old man presented with a large, infected right atrial thrombus that was refractory to anticoagulants and several courses of antibiotics. The risk of surgical removal of the thrombus, which was associated with a pacemaker electrode, was considered prohibitive. The patient was treated for 7 days with low-dose...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4950250709

    authors: Chuang S,Mehta RH,Fay WP

    更新日期:2002-07-01 00:00:00

  • Practical algorithms for pharmacologic management of the post myocardial infarction patient.

    abstract::The pharmacologic management of the patient post myocardial infarction (MI) aims to achieve several goals. Chief among these is to prevent subsequent events, which include death, reinfarction, and rehospitalization. Secondary goals include preventing arrhythmias, minimizing left ventricular (LV) remodeling, and preven...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.4960281306

    authors: Reiffel JA,American Heart Association.,American College of Cardiology.

    更新日期:2005-11-01 00:00:00

  • The potential association between common comorbidities and severity and mortality of coronavirus disease 2019: A pooled analysis.

    abstract:BACKGROUD:The association between underlying comorbidities and cardiac injury and the prognosis in coronavirus disease 2019 (COVID-19) patients was assessed in this study. HYPOTHESIS:The underlying comorbidities and cardiac injury may be associated with the prognosis in COVID-19 patients. METHODS:A systematic search ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.23465

    authors: Luo L,Fu M,Li Y,Hu S,Luo J,Chen Z,Yu J,Li W,Dong R,Yang Y,Tu L,Xu X

    更新日期:2020-12-01 00:00:00

  • Cutting balloon angioplasty and stent implantation for aorto-ostial lesions: clinical outcome and 1-year follow-up.

    abstract:BACKGROUND:Percutaneous interventions for aorto-ostial narrowing of native coronary arteries are challenging because of early elastic recoil after the procedure and the high restenosis rate. Cutting balloon angioplasty may reduce this complication. HYPOTHESIS:The purpose of the study was to evaluate the clinical outco...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20351

    authors: Nassar H,Gotsman I,Gerganski P,Moseri M,Lotan C,Gotsman M

    更新日期:2009-04-01 00:00:00

  • Combined use of warfarin and oral P2Y12 inhibitors in patients with atrial fibrillation and acute coronary syndrome.

    abstract:BACKGROUND:Although atrial fibrillation (AF) occurs frequently in patients hospitalized with acute coronary syndrome (ACS), strategies for prevention of thromboembolic complications are poorly characterized. HYPOTHESIS:We sought to examine exposure to warfarin and P2Y12 inhibitors and clinical outcomes among patients ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22231

    authors: Jones WS,Mi X,Patel MR,Mills R,Hernandez AF,Curtis LH

    更新日期:2014-03-01 00:00:00

  • Platelet reactivity in response to loading dose of atorvastatin or rosuvastatin in patients with stable coronary disease before percutaneous coronary intervention: The STATIPLAT randomized study.

    abstract:BACKGROUND:The acute effects of statin loading dose (LD) on platelet reactivity in patients with chronic stable angina (CSA) are not completely clear. HYPOTHESIS:We hypothesized that LDs of atorvastatin and rosuvastatin have different pharmacodynamic acute effects on platelet aggregability in CSA patients with baselin...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/clc.22709

    authors: Godino C,Pavon AG,Mangieri A,Salerno A,Cera M,Monello A,Chieffo A,Magni V,Cappelletti A,Margonato A,Colombo A

    更新日期:2017-08-01 00:00:00

  • Endovascular stents: preliminary clinical results and future developments.

    abstract::At present, there is an exponential use of new interventional techniques whose proper role and value have not yet been defined. The intracoronary stent is just one example. There is no doubt that stents can be implanted with a high technical success rate associated with highly predictable immediate angiographic result...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.4960160503

    authors: de Jaegere PP,de Feyter PJ,van der Giessen WJ,Serruys PW

    更新日期:1993-05-01 00:00:00

  • Immediate and long-term results following balloon mitral valvotomy in patients with atrial fibrillation.

    abstract:BACKGROUND:The purpose of this study was to examine the influence of atrial fibrillation (AF) on the immediate and long-term outcome of patients undergoing balloon mitral valvotomy (BMV). HYPOTHESIS:Patients with atrial fibrillation fair poorly after balloon mitral valvotomy. METHODS:There were a total of 818 consecu...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22068

    authors: Nair KK,Pillai HS,Thajudeen A,Krishnamoorthy KM,Sivasubramonian S,Namboodiri N,Sasidharan B,Ganapathy S,Varaparambil A,Titus T,Tharakan J

    更新日期:2012-12-01 00:00:00

  • Atrial fibrillation: is there a role for low-molecular-weight heparin?

    abstract::Atrial fibrillation (AF) is the most common form of tachyarrhythmia and carries a significant risk of serious thromboembolic complications. Anticoagulation is used for long-term thromboprophylaxis and for short-term management in a number of clinical situations, among which is the medical or electrical cardioversion o...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960241306

    authors: Camm AJ

    更新日期:2001-03-01 00:00:00

  • Effect of cibenzoline on regional left ventricular function in hypertrophic obstructive cardiomyopathy.

    abstract:BACKGROUND:Cibenzoline, a class Ia antiarrhythmic drug, can be used to relieve left ventricular (LV) outflow obstruction in hypertrophic obstructive cardiomyopathy (HOCM). However, the mechanism of this agent in HOCM has been controversial. HYPOTHESIS:This study was designed to investigate the effect of cibenzoline on...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960230911

    authors: Kondo I,Mizushige K,Nozaki S,Hirao K,Iwado Y,Ohmori K,Matsuo H

    更新日期:2000-09-01 00:00:00

  • Acute coronary syndromes: selective vs early invasive strategies.

    abstract::Recommendations in the 2007 update of the American College of Cardiology/American Heart Association guidelines for patients with non-ST-elevation myocardial infarction (NSTEMI) provide considerable latitude regarding treatment choices and care pathways. Nevertheless, as accumulating evidence leads to increased recomme...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.20671

    authors: Boden WE,Gupta V

    更新日期:2009-11-01 00:00:00

  • Gait speed and dependence in activities of daily living in older adults with severe aortic stenosis.

    abstract:BACKGROUND:In the transcatheter aortic valve replacement era, characterization of functional status in older adults with aortic stenosis (AS) is essential. Gait speed (GS) is emerging as a marker of frailty and predictor of outcomes in older adults undergoing cardiovascular intervention. The objective of this study was...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.21974

    authors: Green P,Woglom AE,Genereux P,Maurer MS,Kirtane AJ,Hawkey M,Schnell S,Sohn J,Moses JW,Leon MB,Smith CR,Williams M,Kodali S

    更新日期:2012-05-01 00:00:00

  • Influence of exercise training soon after myocardial infarction on regional myocardial perfusion and resting left ventricular function.

    abstract::There is scant information regarding the effect of exercise training begun soon after hospital discharge for myocardial infarction (MI) with respect to subsequent improvement in exercise tolerance, enhancement of regional myocardial perfusion, or left ventricular function. Accordingly, 19 post-MI patients (mean age 53...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960150105

    authors: Beller GA,Murray GC,ErkenBrack SK

    更新日期:1992-01-01 00:00:00

  • Eicosapentaenoic acid therapy is associated with decreased coronary plaque instability assessed using optical frequency domain imaging.

    abstract:BACKGROUND:The relationship between eicosapentaenoic acid (EPA) therapy and coronary plaque stability assessed by optical frequency domain imaging (OFDI) has not been thoroughly described. HYPOTHESIS:EPA therapy is associated with decreased plaque instability in patients undergoing percutaneous coronary intervention (...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.23185

    authors: Konishi T,Sunaga D,Funayama N,Yamamoto T,Murakami H,Hotta D,Nojima M,Tanaka S

    更新日期:2019-06-01 00:00:00

  • Statin therapy in the reduction of cardiovascular events in patients undergoing intermediate-risk noncardiac, nonvascular surgery.

    abstract:BACKGROUND:Hydroxymethylglutaryl-coenzyme A reductase inhibitors (statins) reduce perioperative cardiac events in high-risk patients undergoing cardiovascular surgery. However, there is paucity of data on the role of statins in patients undergoing intermediate-risk noncardiac, nonvascular surgery (NCNVS). HYPOTHESIS:S...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22135

    authors: Raju MG,Pachika A,Punnam SR,Gardiner JC,Shishehbor MH,Kapadia SR,Abela GS

    更新日期:2013-08-01 00:00:00

  • Predictors of very late recurrence of atrial fibrillation after circumferential pulmonary vein ablation.

    abstract:BACKGROUND:Early recurrence of atrial fibrillation (ERAF) after catheter ablation is common and has been thoroughly studied. However, very late recurrence of atrial fibrillation (VLRAF) is rarely researched, and its characteristics have not been determined. HYPOTHESIS:The aim of this study was to investigate the clini...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20340

    authors: Tao H,Liu X,Dong J,Long D,Tang R,Zheng B,Kang J,Yu R,Tian Y,Ma C

    更新日期:2008-10-01 00:00:00

  • Torsade de pointes complicating drug treatment of low-malignant forms of arrhythmia: four cases reports.

    abstract::In patients with malignant ventricular arrhythmias, antiarrhythmic therapy is known to carry a substantial risk of proarrhythmia. This risk is usually considered to be low when supraventricular arrhythmias or benign ventricular arrhythmias are considered. We were able to collect data on four patients without a history...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960170410

    authors: Faber TS,Zehender M,Van de Loo A,Hohnloser S,Just H

    更新日期:1994-04-01 00:00:00

  • Coronary hemodynamic effects of systemic thrombolysis in patients with unstable angina.

    abstract::Intracoronary (i.c.) thrombus is a frequent finding in patients with unstable angina (UA). Accordingly, thrombolytic treatment could be beneficial, as resolution of thrombus might result in increased delivery of blood flow to the ischemic regions. To test this hypothesis, we studied 13 patients with active UA and ST-s...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960150206

    authors: Pozzati A,Bugiardini R,Ottani F,Morgagni GL,Puddu P

    更新日期:1992-02-01 00:00:00

  • Clinical characteristics and outcomes of hypertrophic cardiomyopathy in Taiwan--a tertiary center experience.

    abstract:BACKGROUND:Most information concerning hypertrophic cardiomyopathy has been derived from western countries and Japan. HYPOTHESIS:Patients with hypertrophic cardiomyopathy in Taiwan may have a distinct morphology and clinical picture. METHODS:Information from 163 consecutive patients with hypertrophic cardiomyopathy a...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20057

    authors: Lee CH,Liu PY,Lin LJ,Chen JH,Tsai LM

    更新日期:2007-04-01 00:00:00

  • Culprit plaque characteristics in women vs men with a first ST-segment elevation myocardial infarction: In vivo optical coherence tomography insights.

    abstract:BACKGROUND:It is unclear whether more severe coronary atherosclerosis is a prerequisite to an initial acute coronary event in women vs men. HYPOTHESIS:Women may have more severe coronary atherosclerosis than men in patients with acute coronary event. METHODS:We used intravascular optical coherence tomography (OCT) to...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22825

    authors: Sun R,Sun L,Fu Y,Liu H,Xu M,Ren X,Yu H,Dong H,Liu Y,Zhu Y,Tian J,Yu B

    更新日期:2017-12-01 00:00:00

  • Lifestyle change and high-density lipoprotein change: the US Department of Veterans Affairs Normative Aging Study.

    abstract:BACKGROUND:We sought to determine whether lifestyle modifications are associated with high-density lipoprotein cholesterol (HDL-C) change in a cohort with long-term follow-up. HYPOTHESIS:Changes in alcohol consumption, smoking, or body mass index (BMI) are associated with within-individual changes in HDL-C. METHODS:W...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.21978

    authors: Rahilly-Tierney C,Vokonas P,Gaziano JM,Spiro A 3rd

    更新日期:2012-01-01 00:00:00

  • Acute changes in left ventricular diastolic function: cigarette smoking versus nicotine gum.

    abstract:BACKGROUND:Echocardiographic evidence of diastolic dysfunction has been demonstrated during acute cigarette smoking in patients with coronary artery disease. Similar studies in healthy patients have shown conflicting results. Furthermore, it is unclear whether nicotine or some other cigarette-related substance is respo...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960290205

    authors: Gembala MI,Ghanem F,Mann CA,Sorrell VL

    更新日期:2006-02-01 00:00:00

  • Stress damage to nonischemic divisions of the heart in experimental infarction and its prevention.

    abstract::Recently, it has been shown that nonischemic parts of the heart in myocardial infarction were separated from ischemic damaged ones by a sharp border zone. In this connection, the disturbance of contractile function of the myocardium of nonischemic parts is suggested to result from the infarction-concomitant emotional-...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960060403

    authors: Meerson FZ

    更新日期:1983-04-01 00:00:00