Abstract：
BACKGROUND AND PURPOSE:The aim of this study was to assess cognitive impairment in patients with relapsing-remitting multiple sclerosis (RR-MS) and to evaluate the correlation of cognitive impairment with physical disability and MRI lesion volume. MATERIAL AND METHODS:Sixty patients with RR-MS and 50 healthy controls were assessed using neuropsychological tests. All the patients were subjected to MRI examination using PD/T2 and T1 sequences, and clinical evaluation with the EDSS scale was applied. RESULTS:Selective cognitive impairment was found in 40% of the RR-MS group, and broad, overall cognitive dysfunction was found in 15% of patients. A correlation was found between neurological signs and memory deficits and psychomotor speed. The mean total lesion volume (TLV) was significantly higher in patients with selective and overall cognitive impairment than in those without (8060 vs. 3183 mm3, p=0.001; 7234 vs. 3138 mm3, p=0.004, respectively). There was no difference in TLV between RR-MS patients with selective or overall cognitive impairment (8060 vs. 7234 mm3, p=0.134). Moderate correlations were found between nonverbal memory, verbal fluency and abstract reasoning tests and TLV. CONCLUSIONS:Cognitive impairment is present in more than 50% of patients with RR-MS, and they are mainly selective deficits. The correlation between physical disability and cognitive impairment was not significant, except for memory deficits and psychomotor speed. There is a correlation between TLV and presence of cognitive impairment, but no correlation between TLV and pattern of cognitive impairment.
journal_name
Neurol Neurochir Poljournal_title
Neurologia i neurochirurgia polskaauthors
Karlińska I,Siger M,Lewańska M,Selmaj Ksubject
Has Abstractpub_date
2008-09-01 00:00:00pages
416-23issue
5eissn
0028-3843issn
1897-4260pii
11363journal_volume
42pub_type
杂志文章abstract：:Marchiafava-Bignami disease (MBD) is a rare fatal neurological disorder characterized by demyelination, primary degeneration, and necrosis of the corpus callosum. Although MBD is mostly associated with chronic alcohol consumption and malnutrition, it has been reported in non-alcoholic patients. Serotonin syndrome is a...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2017.10.011
更新日期：2018-03-01 00:00:00
abstract：:Visual evoked potentials in response to checkerboard reversal pattern were evaluated in 160 patients: 24 with isolated retrobulbar optic neuritis, 100 with unquestionable and probable multiple sclerosis, 36 with paraparesis or with disseminated changes of unestablished aetiology (degenerative or inflammatory) and in 8...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1987-11-01 00:00:00
abstract：:Vertebral haemangioma is a slowly growing benign tumour arising from blood vessels. Haemangioma of the vertebrae is usually asymptomatic. Neurological symptoms occur when haemangioma causes compression of nerve roots or spinal cord. In this paper a case of a 59 year-old woman with, vertebral body L2 haemangioma is rep...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1999-03-01 00:00:00
abstract：:The acute phase of spinal cord injury includes primary and secondary pathological patterns. Primary patterns include the effects of contusion, laceration, stretch of neural tissue and direct vascular trauma. These changes are irreversible. Secondary patterns include posttraumatic ischemic changes, loss of energy metab...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND AND PURPOSE:The aim of this study was to perform a validation analysis of the Polish adaptation of the Multiple Sclerosis International Quality of Life Questionnaire, MusiQoL. MATERIAL AND METHODS:Validation analysis included the translation of the original English version into Polish according to translati...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/s0028-3843(14)60076-1
更新日期：2011-05-01 00:00:00
abstract：:The Publisher regrets that this article is an accidental duplication of an article that has already been published, 10.1016/j.pjnns.2018.02.008. The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/articl...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2018.04.004
更新日期：2018-05-17 00:00:00
abstract：BACKGROUND:Compared with surgical resection, endoscopic transsphenoidal surgery (TSS) for cholesterol granuloma (CG) in the petrous apex (PA) is associated with local recurrence due to obstruction of the drainage route. We present a detailed procedure of an endoscopic TSS using pedicle vascularized nasoseptal flap (PVN...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2016.08.006
更新日期：2016-01-01 00:00:00
abstract：:The authors analysed 95 SEEG records in epileptics with prevalent temporal-lobe changes comparing the bioelectric activity of the brain recorded simultaneously in the amygdala, hippocampus, temporal cortex and cranial surface during these investigations and relating them to EEG records obtained before the operation. I...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1979-05-01 00:00:00
abstract：BACKGROUND AND PURPOSE:The aim of this retrospective study was to assess the effectiveness of aneurysm clipping by computed tomography angiography (CTA) in a long-term follow-up. MATERIAL AND METHODS:The CTA examination was performed in 119 patients who had 143 aneurysms clipped. The examinations were performed 3 to 1...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.5114/ninp.2012.31549
更新日期：2013-01-01 00:00:00
abstract：:Deep brain stimulation (DBS) of the ventral intermediate thalamic nucleus (Vim) has been recently introduced by Benabid and his colleagues as a new surgical procedure in the treatment of tremor-dominant Parkinson's disease (PD). The advantage of DBS Vim over lesioning (thalamotomy) is its reversibility and adjustabili...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
abstract：:Acute aortic dissection is a rare, life-threatening condition requiring early recognition and proper treatment. Although chest pain remains the most frequent initial symptom, clinical manifestation of aortic dissection varies. Rarely aortic dissection starts with neurological symptoms such as ischemic stroke, which is...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2015.04.009
更新日期：2015-01-01 00:00:00
abstract：INTRODUCTION:We sought to evaluate quality of life patients with myasthenic crisis before and after therapeutic plasma exchange. MATERIALS AND METHODS:In our study we conducted an assessment of the quality of life with the use of the questionnaire SF-36, when executed eleven therapeutic plasma exchange. The assessment...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2016.07.005
更新日期：2016-01-01 00:00:00
abstract：:In 62 women the course of epilepsy was analysed at the age of puberty from 11 to 15 years of life. In 19 cases the course of the disease remained unchanged at that time, in 20 cases the seizures disappeared or became less frequent, in 20 cases the frequency of seizures increased, other types of seizures developed, or ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1975-09-01 00:00:00
abstract：UNLABELLED:The aim of the study was to characterize vascular stroma in glioblastoma (GB), to analyze its immunomorphological features, and to seek a relationship between patients' age and characteristics of the tumor microcirculation. Subjects in the study were 38 patients with GB, divided into two groups according to ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:The authors describe a case of spinal intracanal cysticercosis. The cysts were situated intradurally, provoking radicular symptoms: pain, paresis. CT investigations showed herniation of discs L4/L5 and L5/S1 interpreted as the cause of the mentioned symptoms. Surgical treatment included discectomy L4/L5 and L5/S1. Rec...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2000-07-01 00:00:00
abstract：:The majority of reports indicate that blood platelet membrane fluidity is increased in Alzheimer's disease (AD) patients. The increased membrane fluidity implies that platelet membrane receptors are less exposed to the external environment. To verify this hypothesis we tried to estimate platelet membrane fluidity at i...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1999-11-01 00:00:00
abstract：:Multiple sclerosis (MS) should be differentiated with diseases causing disseminated lesions of central nervous system or imitating clinical course of MS. Clinical course and results of laboratory investigations also immunological tests should be taken into account in differential diagnosis of MS. We present four patie...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:We present a rare case of bilateral crocodile tears syndrome (CTS) in the course of Melkersson-Rosenthal syndrome. Melkersson-Rosenthal syndrome is characterised by a triad of recurrent orofacial swelling, relapsing facial paralysis, and fissured tongue. The classic triad is infrequent and oligosymptomatic variants ar...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2006-09-01 00:00:00
abstract：:Investigations were performed on 13 cats with epileptogenic focus developed after sectioning the optic chiasm and corpus callosum. Learning was begun 3 months after producing the epileptogenic focus by the aluminium method when it was bioelectrically active. Additionally in 6 cats DPH in daily doses of 10--15 mg/kg wa...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1976-03-01 00:00:00
abstract：:Complications of transpedicular stabilizations of thoraco-lumbar burst fractures are presented on the basis of literature review and own experiences. Unstable thoraco-lumbar burst fractures create the most difficult biomechanical conditions for a stabilizer. A literature review was done to estimate the effectiveness o...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2006-03-01 00:00:00
abstract：:Multiple spatio dipole structure of brain cortex has been developed to transform the traditional scalp EEG into an image of source activities. Computer use of complex calculation algorythms identify those brain regions which are active and contribute to the epileptiform discharges. The Chair and Department of Developm...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:The paper contains a clinical analysis of 23 cases of dorsomedial intervertebral disc prolapse in the lumbar spine treated surgically with stress laid on late results, which were evaluated in follow up. The results were compared with the rate of increase of clinical manifestations, clinical conditions of the patients,...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1981-05-01 00:00:00
abstract：BACKGROUND AND AIM:General anesthesia (GA) is the most commonly used anesthetic technique for spinal surgery. This study aimed to compare spinal anesthesia (SA) and GA in patients undergoing spinal surgery, in terms of perioperative outcome and cost effectiveness. MATERIALS AND METHODS:The study included 80 patients w...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.pjnns.2014.05.005
更新日期：2014-01-01 00:00:00
abstract：:Massive hematoma of the corpus callosum caused by blunt head trauma is an extremely rare lesion. Most frequent traumatic lesions involve the corpus callosum are diffuse axonal injuries. They might be associated with small hemorrhagic foci in the hemispheric and brain stem white matter, intraventricular hemorrhages, su...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2016.04.005
更新日期：2016-07-01 00:00:00
abstract：:For assessment of the effect of trihexiphenidil on the excitability state of the alpha-motoneurons of the plantar flexor of the foot in patients with drug-induced parkinsonian rigidity curves of the excitability of motoneurons of the soleus muscle were plotted in two variants of experiments: I. with afferent stimulati...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：:Determinations of AMP-aminohydrolase activity were done in muscles in 34 cases of different neuromuscular diseases, and 30 subjects without skeletal muscle changes. In the group of patients Duchenne's progressive dystrophy accounted for 10 cases, the remaining patients had limb-girdle dystrophy, polymyositis, myotonia...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1979-07-01 00:00:00
abstract：:Most recent studies on transcranial Doppler (TCD) in the acute phase of ischemic stroke are reviewed in this paper. TCD is a highly sensitive and specific method of quick, bedside assessment of cerebrovascular circulation hemodynamics in the acute phase of ischemic stroke. The following issues are discussed in the pap...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:14 patients with Tick-borne Encephalitis (TBE) aged 21-64 (mean = 42.3) were analysed. The activity of superoxide dismutase (SOD), glutathione reductase (GSSG-R), glutathione peroxidase (GSH-Px), concentrations of malondialdehyde (MDA) and total sulphydryl groups (-SH) were measured in cerebrospinal fluid (CSF). Contr...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2002-07-01 00:00:00
abstract：:Forty-five cases of pituitary adenomas with clinical characteristics of acromegaly treated surgically from an approach through the nose and sphenoid sinus are presented. After the operation the somatic features of acromegaly decreased in 66% of cases, headaches regressed in 88%, visual field defects disappeared in 20%...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1982-07-01 00:00:00
abstract：:The authors report the results of investigations of 33 healthy subjects and 33 patients with manifestations of intracranial circulatory disturbances in the vascularization area of the vertebrobasilar system. Type II rheography was used. All curves from the vertebral, vertebromastoid and frontomastoid leads were averag...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1982-07-01 00:00:00
