The effect of isoflurane on cerebrospinal fluid pressure in patients undergoing neurosurgery.

Abstract:

:Ten patients with intracerebral tumours (TC) and 13 patients with subarachnoid haemorrhage (SAH) from a ruptured cerebral arterial aneurysm were studied before intracranial surgery, and during a 3-h postoperative period. Cerebrospinal fluid pressure (CSFP) determined by an intraventricular (TC group) or intraspinal (SAH group) catheter, and mean arterial blood pressure (MABP) were recorded under neurolept anaesthesia (control) followed by isoflurane inhalation. These two measurements were performed during normocapnia. A third measurement was made during hypocapnia, with unchanged isoflurane concentration. After the experimental period, isoflurane remained the main anaesthetic agent throughout the surgical procedure. After recovery from anaesthesia, the patients were monitored with CSFP and blood pressure during the first postoperative hours, and the quality of breathing was assessed by hourly blood-gas analyses. The results show that isoflurane causes a 10-14% reduction of MABP with no further changes during hyperventilation. Mean CSFP increased 27% in the TC group, and 12% in the SAH group after isoflurane induction and decreased from these levels by 29% during hyperventilation in both groups. Consequently, the impact on cerebral perfusion pressure (CPP) by isoflurane was a 19% and 21% mean decrease in the TC and SAH group, respectively. Controlled hyperventilation reduced this effect by partially restoring control CPP values, with 8% and 14% increase, respectively. In the postoperative follow-up, all patients had normal breathing and blood pressure with low values of CSFP. It is concluded that isoflurane can be used in intracranial surgery with adequate safety if combined with controlled hyperventilation.

authors

Gordon E,Lagerkranser M,Rudehill A,von Holst H

doi

10.1111/j.1399-6576.1988.tb02696.x

subject

Has Abstract

pub_date

1988-02-01 00:00:00

pages

108-12

issue

2

eissn

0001-5172

issn

1399-6576

journal_volume

32

pub_type

杂志文章
  • Effects of intrathecal bupivacaine in conjunction with hypothermia on neuronal protection against transient spinal cord ischemia in rats.

    abstract:BACKGROUND:Excitotoxic neuronal injury from ischemia may be reduced by local anesthetics. We investigated the neuroprotective effects of intrathecally administered bupivacaine and hypothermia in a rat model of transient spinal cord ischemia. METHODS:PE-10 intrathecal catheter-implanted male Sprague-Dawley rats were ra...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.2006.01163.x

    authors: Lee JR,Han SM,Leem JG,Hwang SJ

    更新日期:2007-01-01 00:00:00

  • Propofol 2 mg/kg is superior to propofol 1 mg/kg for tracheal intubation in children during sevoflurane induction.

    abstract:BACKGROUND:Propofol has been used to facilitate tracheal intubation within a short time of sevoflurane induction without a muscle relaxant in children. We compared as the primary outcome the incidence of excellent intubating conditions after 8% sevoflurane and propofol 1 or 2 mg/kg. METHODS:One hundred and four patien...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.2011.02423.x

    authors: Siddik-Sayyid SM,Taha SK,Aouad MT,Abdallah FW,Al Alami AA,Kanazi GE

    更新日期:2011-05-01 00:00:00

  • Heat and moisture exchangers and the body temperature: a peroperative study.

    abstract::The importance of conditioning the inhaled gas for maintaining the body temperature during artificial respiration was investigated. The mean body temperature (MBT) was deduced from readings from five measuring sites, four of which were situated at the skin and the fifth in the rectum. Temperature recordings were made ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1990.tb03141.x

    authors: Eckerbom B,Lindholm CE

    更新日期:1990-10-01 00:00:00

  • Parenteral nutrition in preterm neonates with and without carnitine supplementation.

    abstract::The effects of carnitine supplementation on fat and glucose metabolism and carnitine balance were studied in 12 preterm neonates receiving full or partial parenteral nutrition (PN) for 5 to 21 days. The gestational age ranged from 27 to 32 weeks and the birth weight from 790 to 2090 g. The neonates were assigned at ra...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1990.tb03132.x

    authors: Larsson LE,Olegård R,Ljung BM,Niklasson A,Rubensson A,Cederblad G

    更新日期:1990-08-01 00:00:00

  • Aminotransferases after experimental pneumoperitoneum in dogs.

    abstract:BACKGROUND:Laparoscopic surgery has rapidly become a popular and widely used technique. Elevated intra abdominal pressure due to gas insufflation for laparoscopic surgery may result in a number of local and systemic effects on the organism. The effects of pneumoperitoneum on the cardiovascular and respiratory system ar...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.0001-5172.2004.00431.x

    authors: Nesek-Adam V,Rasic Z,Kos J,Vnuk D

    更新日期:2004-08-01 00:00:00

  • The efficacy of intrathecal injection of sufentanil using a microspinal catheter for labor analgesia.

    abstract::Intrathecal sufentanil can provide labor analgesia. We investigated the efficacy of multiple injections and the maternal and neonatal effects of intrathecal sufentanil during labor. Seventeen healthy women in active labor received multiple injections of intrathecal sufentanil of 5 micrograms each through microspinal c...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1996.tb04421.x

    authors: Abboud TK,Zhu J,Sharp R,LaGrange C,Rosa C,Kassells B

    更新日期:1996-02-01 00:00:00

  • Risk factors of acute kidney injury in children after cardiac surgery.

    abstract:BACKGROUND:The objective of this retrospective study was to determine the risk factors for acute kidney injury (AKI), including albumin, in children who underwent cardiac surgery. In addition, we evaluated the association between preoperative serum albumin level and postoperative AKI in these patients. METHODS:This re...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aas.13210

    authors: Lee JH,Jung JY,Park SW,Song IK,Kim EH,Kim HS,Kim JT

    更新日期:2018-11-01 00:00:00

  • Slow rewarming improves jugular venous oxygen saturation during rewarming.

    abstract:BACKGROUND:There have been many studies regarding the etiology of postoperative cognitive dysfunction after coronary artery bypass graft (CABG) surgery. Although its etiology remains unresolved, one possible factor related to postoperative cognitive dysfunction is a reduced internal jugular venous oxygen hemoglobin sat...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1399-6576.2003.00063.x

    authors: Kawahara F,Kadoi Y,Saito S,Goto F,Fujita N

    更新日期:2003-04-01 00:00:00

  • Atelectasis and pulmonary shunting during induction of general anaesthesia--can they be avoided?

    abstract:BACKGROUND:Gas exchange is regularly impaired during general anaesthesia with mechanical ventilation. A major cause of this disorder appears to be atelectasis and consequently pulmonary shunt. After re-expansion, atelectasis reappears very slowly if 30% oxygen in nitrogen is used, but much faster if 100% oxygen is used...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1996.tb04483.x

    authors: Rothen HU,Sporre B,Engberg G,Wegenius G,Reber A,Hedenstierna G

    更新日期:1996-05-01 00:00:00

  • Intravenous diadenosine tetraphosphate in dogs. Cardiovascular effects and influence on blood gases.

    abstract::Diadenosine tetraphosphate (AP4A) has a considerable vasodilating effect. Its dose was adjusted to decrease mean arterial pressure (MAP) by 20%, 40%, 50%, 60%, and 80% of the pretreatment value, and the effects on hemodynamics and gas exchange were evaluated. AP4A produced a dose-dependent decrease in MAP within the r...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1994.tb03890.x

    authors: Kikuta Y,Sekine A,Tezuka S,Okada K,Yamaura T,Nakajima H

    更新日期:1994-04-01 00:00:00

  • Age-related effects in the EEG during propofol anaesthesia.

    abstract:BACKGROUND:Age-related differences in the spectral composition of the EEG in induction and emergence times, and in drug consumption during propofol anaesthesia were investigated. METHODS:The EEGs of 60 female patients between 22 and 85 years of age were monitored continuously during standardized induction of anaesthes...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1111/j.1399-6576.2004.00258.x

    authors: Schultz A,Grouven U,Zander I,Beger FA,Siedenberg M,Schultz B

    更新日期:2004-01-01 00:00:00

  • Effects of olprinone, a new phosphodiesterase inhibitor, on gastric intramucosal acidosis and systemic inflammatory responses following hypothermic cardiopulmonary bypass.

    abstract:BACKGROUND:Phosphodiesterase (PDE) III inhibitors have both an inotropic and a peripheral vasodilatory effect, and also inhibit the activation of macrophages. Thus a newly developed PDE III inhibitor, olprinone, could modify gastric intramucosal pH (pHi), systemic oxygen consumption, and systemic inflammatory responses...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1399-6576.2001.045004427.x

    authors: Yamaura K,Akiyoshi K,Irita K,Taniyama T,Takahashi S

    更新日期:2001-04-01 00:00:00

  • Anaesthetic practice and postoperative pulmonary complications.

    abstract::The aim of this study was to identify risk factors associated with postoperative pulmonary complications. The influence of the anaesthetic technique was evaluated (i.e. general contra regional anaesthesia and long contra intermediately acting muscle relaxants (pancuronium and atracurium)) taking into account the patie...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1992.tb03570.x

    authors: Pedersen T,Viby-Mogensen J,Ringsted C

    更新日期:1992-11-01 00:00:00

  • Anesthetic effect of epidural anesthesia with cephalad or caudad catheterization for ankle surgery or hemorrhoidectomy.

    abstract:BACKGROUND:The larger size of the first sacral nerve root has been reported to be an unfavorable factor leading to sacral sparing in epidural anesthesia. Previous studies have shown that an adequate analgesic effect of the epidural block was achieved with the catheter placement in the caudal direction. In this study, t...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.2005.00620.x

    authors: Chou WY,Hsu CJ,Cheng JT,Yang LC,Lin CR,Chia YY,Yu SW,Tan PH

    更新日期:2005-03-01 00:00:00

  • Direct myocardial depressant effect of naloxone: mechanical and electrophysiological actions in vitro.

    abstract:BACKGROUND:Naloxone, an opioid antagonist, has a cardiovascular pressor effect and has been used in various types of shock states. The aim was to determine the non-opioid effect on direct cardiac muscle contractility and explore the mechanism using guinea pig right ventricular papillary muscles. METHODS:With instituti...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.2004.00267.x

    authors: Kim KJ,Chung NS,Park WK

    更新日期:2004-01-01 00:00:00

  • Propofol and isoflurane induced EEG burst suppression patterns in rabbits.

    abstract::The aim of this study was to compare propofol produced EEG burst suppression with isoflurane produced burst suppression in rabbits and to see whether rabbits can serve as models in studying the effects of different anaesthetics on human EEG. We recorded EEG of eight rabbits anaesthetised with isoflurane and propofol. ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1995.tb04176.x

    authors: Hartikainen K,Rorarius M,Mäkelä K,Yli-Hankala A,Jäntti V

    更新日期:1995-08-01 00:00:00

  • Central cholinergic action produces antagonism to ketamine anesthesia.

    abstract::Ketamine sometimes produces posthypnotic emergency reactions, such as prolonged hallucination or delirium. In a previous paper, we showed that physostigmine, an anticholinesterase agent, counteracts the manifestation of effects of ketamine at some doses. In the present study, we investigated the mechanism of the antag...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1992.tb03497.x

    authors: Mimura M,Namiki A,Kishi R,Ikeda T,Miyake H,Iwasaki H

    更新日期:1992-07-01 00:00:00

  • Bilateral continuous paravertebral catheters for reduction mammoplasty.

    abstract::Surgical procedures of the breast can result in significant postoperative pain. Paravertebral nerve blocks have been used successfully in the management of analgesia after breast surgery but are limited by a single injection. This report describes the use of bilateral paravertebral catheters to provide extended analge...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1399-6576.2002.460820.x

    authors: Buckenmaier CC 3rd,Steele SM,Nielsen KC,Martin AH,Klein SM

    更新日期:2002-09-01 00:00:00

  • Dexamethasone for pain after outpatient shoulder surgery: a randomised, double-blind, placebo-controlled trial.

    abstract:BACKGROUND:Dexamethasone has analgesic properties when given intravenously before surgery, but the optimal dose has not been determined. We hypothesised that a dose of 40 mg dexamethasone would improve analgesia after outpatient shoulder surgery compared with 8 mg. METHODS:A randomised, double-blind, placebo-controlle...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/aas.12333

    authors: Bjørnholdt KT,Mønsted PN,Søballe K,Nikolajsen L

    更新日期:2014-07-01 00:00:00

  • Sublingual premedication with brotizolam.

    abstract::This randomized, double-blind and double-dummy study was carried out in order to compare the perioperative sedation after premedication with either brotizolam 0.25-0.50 mg sublingually or diazepam 5-10 mg orally. Sixty-two patients aged 18-60 years scheduled for minor gynaecological surgery in general anaesthesia were...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1992.tb03560.x

    authors: Laub M,Espersen K,Ejlersen E,Krintel JJ

    更新日期:1992-11-01 00:00:00

  • Pharmacokinetics of 0.2% ropivacaine and 0.2% bupivacaine following caudal blocks in children.

    abstract:BACKGROUND:Ropivacaine is the first S-enantiomer aminoamide local anaesthetic in clinical use, and has been found to be less toxic than bupivacaine. Caudal ropivacine has been shown to cause less motor blockade and longer duration of analgesia in the postoperative period than bupivacaine in children. Plasma levels of r...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1399-6576.2000.440911.x

    authors: Ala-Kokko TI,Partanen A,Karinen J,Kiviluoma K,Alahuhta S

    更新日期:2000-10-01 00:00:00

  • Hypertonic-hyperoncotic solution increases canine lymph flows.

    abstract:BACKGROUND:Hypertonic-hyperoncotic solutions (HHS) have attracted a lot of interest in the treatment of various forms of hypovolaemic conditions during the last decade. It has been speculated that HHS might even be of therapeutic value in normo- and hypervolaemic conditions by mobilising extravascular fluid. METHODS:W...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1996.tb04398.x

    authors: Wickerts CJ,Berg B,Blomqvist H

    更新日期:1996-01-01 00:00:00

  • Chloroprocaine 40 mg produces shorter spinal block than articaine 40 mg in day-case knee arthroscopy patients.

    abstract:BACKGROUND:Articaine and chloroprocaine have recently gained interest as short-acting spinal anaesthetics. Based on previous work comparing articaine 60 mg with chloroprocaine 40 mg, we hypothesised that articaine 40 mg and chloroprocaine 40 mg would produce similar spinal anaesthesa regarding block onset, maximal spre...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/aas.12107

    authors: Förster JG,Rosenberg PH,Harilainen A,Sandelin J,Pitkänen MT

    更新日期:2013-08-01 00:00:00

  • Effects of a leucocyte depleting arterial line filter on perioperative proteolytic enzyme and oxygen free radical release in patients undergoing aortocoronary bypass surgery.

    abstract:BACKGROUND:Proteolytic enzymes and oxygen free radicals released from activated leucocytes contribute significantly to the organ dysfunction associated with cardiopulmonary bypass. Leucocyte depletion during extracorporeal circulation should reduce the release of these toxic compounds and thereby improve postbypass myo...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1399-6576.1999.430414.x

    authors: Mair P,Hoermann C,Mair J,Margreiter J,Puschendorf B,Balogh D

    更新日期:1999-04-01 00:00:00

  • Hemodynamic and catecholamine response to isoflurane versus droperidol in complement to fentanyl anaesthesia.

    abstract::Droperidol (0.03 mg.kg-1 to 0.25 mg.kg-1) with fentanyl has been reported to be less efficient than volatile agents in the prevention of haemodynamic responses to surgery. The aim of this study was to investigate the use of high-dose droperidol in complement to fentanyl in comparison with isoflurane and fentanyl anaes...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1991.tb03259.x

    authors: Tandonnet F,Bourgain JL,McGee K,Comoy E,Truffa-Bachi J

    更新日期:1991-02-01 00:00:00

  • Propofol sedation and gastric emptying in volunteers.

    abstract:BACKGROUND:The purpose of this study was to evaluate the effects of light propofol sedation on gastric emptying and orocecal transit time (OCT). METHODS:Ten healthy male volunteers were studied on 2 occasions separated by at least 1 week and were randomly allocated to receive either propofol sedation or i.v. saline as...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1998.tb05088.x

    authors: Hammas B,Hvarfner A,Thörn SE,Wattwil M

    更新日期:1998-01-01 00:00:00

  • Pneumoperitoneum--a rare complication of cardiopulmonary resuscitation.

    abstract::Pneumoperitoneum following cardiopulmonary resuscitation (CPR) results from a thoracic air leak (pneumothorax, pneumomediastinum) with escape of the air through diaphragmatic apertures (mostly foramen of Winslow) or primary perforation of the gastrointestinal tract (stomach or esophagus). We report three cases of pneu...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1991.tb03279.x

    authors: Hartoko TJ,Demey HE,Rogiers PE,Decoster HL,Nagler JM,Bossaert LL

    更新日期:1991-04-01 00:00:00

  • Pre-operative transthoracic echocardiography in ambulatory surgery-A cross-sectional study.

    abstract:BACKGROUND:Cardiac disease and aberrations in central volume status are risk factors for perioperative complications, and should be identified prior to surgery. This study investigated the benefit of transthoracic echocardiography (TTE) for pre-operative identification of cardiac disease and hypovolemia in ambulatory s...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aas.13620

    authors: Stenberg Y,Lindelöf L,Hultin M,Myrberg T

    更新日期:2020-09-01 00:00:00

  • Shock index as a predictor for short term mortality in helicopter emergency medical services: a registry study.

    abstract:BACKGROUND:The value of shock-index has been demonstrated in hospital triage, but few studies have evaluated its prehospital use. The aim of our study was to evaluate the association between shock-index in prehospital critical care and short-term mortality. METHODS:We analyzed data from the national helicopter emergen...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aas.13765

    authors: Björkman J,Raatiniemi L,Setälä P,Nurmi J

    更新日期:2020-12-19 00:00:00

  • Maternal and foetal effects of remifentanil for general anaesthesia in parturients undergoing caesarean section: a systematic review and meta-analysis.

    abstract:BACKGROUND:Remifentanil has been suggested for the induction of general anaesthesia for caesarean section. We aimed to define remifentanil effects on maternal stress response as well as neonatal effects. METHODS:Relevant articles were retrieved by a systematic literature search. Randomized, controlled trials comparing...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/j.1399-6576.2012.02723.x

    authors: Heesen M,Klöhr S,Hofmann T,Rossaint R,Devroe S,Straube S,Van de Velde M

    更新日期:2013-01-01 00:00:00