Cardiovascular reactivity to psychological stress and carotid intima-media thickness in children.

Abstract:

:The relationship between cardiovascular stress reactivity and carotid artery intima-media thickness (IMT) has been established in adults, but not yet studied in children. Cardiovascular reactivity to an ad lib speech was measured in 20 boys and 20 girls age 11.0 +/- 1.4 years. Measures included heart rate (HR), systolic (SBP) and diastolic (DBP) blood pressure reactivity, and mean common carotid artery IMT. Sequential regression analyses were used to establish the incremental increase in R(2) for the prediction of IMT due to cardiovascular reactivity independent of age, socioeconomic status, race, percentage body fat, and baseline BP or HR. SBP reactivity (beta=0.002, , p<.05), but not DBP reactivity (p=.12) or HR reactivity (p=.82), independently predicted carotid artery IMT. This study provides initial evidence that SBP reactivity is associated with IMT and perhaps the early pathogenesis of cardiovascular disease in childhood.

journal_name

Psychophysiology

journal_title

Psychophysiology

authors

Roemmich JN,Lobarinas CL,Joseph PN,Lambiase MJ,Archer Iii FD,Dorn J

doi

10.1111/j.1469-8986.2008.00776.x

subject

Has Abstract

pub_date

2009-03-01 00:00:00

pages

293-9

issue

2

eissn

0048-5772

issn

1540-5958

pii

PSYP776

journal_volume

46

pub_type

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