Antimicrobial susceptibility of Streptococcus pyogenes in Central, Eastern, and Baltic European Countries, 2005 to 2006: the cefditoren surveillance program.

Abstract:

:The in vitro activity of penicillin, ampicillin, cefditoren, cefotaxime, erythromycin, clarithromycin, and levofloxacin against 763 clinical isolates of Streptococcus pyogenes was determined. Clinically significant isolates collected from November 2005 to December 2006 in the Czech Republic, Slovakia, Hungary, Poland, Romania, Estonia, Latvia, and Lithuania (the latter 3 analyzed as Baltic countries) were studied. No resistance to beta-lactams and levofloxacin was found. The rate of erythromycin resistance in S. pyogenes varied among countries, being low (<10%) in Romania and Baltic countries, intermediate (10-20%) in Poland and Czech Republic, and high (>25%) in Hungary and Slovakia. The predominant (75.0%) erythromycin-resistant phenotype among S. pyogenes isolates was MLS(B). The identification of the prevalence of erythromycin resistance mechanism could have impact on the choice of empiric antibiotic therapy for the clinicians in such countries.

authors

Gracia M,Díaz C,Coronel P,Gimeno M,García-Rodas R,Rodríguez-Cerrato V,del Prado G,Huelves L,Ruiz V,Naves PF,Ponte MC,Granizo JJ,Soriano F

doi

10.1016/j.diagmicrobio.2008.12.018

subject

Has Abstract

pub_date

2009-05-01 00:00:00

pages

52-6

issue

1

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(09)00004-2

journal_volume

64

pub_type

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