Abstract:
:The chiral squaramide catalysts (8-15) were synthesized, and their catalytic efficiency in the enantioselective conjugate addition of pyrazolones to nitroalkenes was described. This protocol provides excellent chemical yields (up to 93%) of chiral 5-methyl-4-(2-nitro-1-arylethyl)pyrazol-3-ol derivatives with high enantioselectivities (up to 97% ee).
journal_name
Chiralityjournal_title
Chiralityauthors
Aydin AE,Culha Sdoi
10.1002/chir.23295subject
Has Abstractpub_date
2021-01-11 00:00:00eissn
0899-0042issn
1520-636Xpub_type
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