Abstract:
OBJECTIVES:To evaluate the longitudinal changes of chest CT findings in patients with chronic hypersensitivity pneumonitis (HP) and identify risk factors for fibrotic progression and acute exacerbation (AE). METHODS:This retrospective study included patients with chronic HP with follow-up CT. Baseline and serial follow-up CT were evaluated semi-quantitatively. Fibrosis score was defined as the sum of the area with reticulation and honeycombing. The modified CT pattern of Fleischner Society idiopathic pulmonary fibrosis diagnostic guidelines was evaluated. Cox proportional hazards regression was performed to determine significant variables associated with fibrotic progression and AEs. RESULTS:Of 91 patients, mean age was 59.1 years and 61.5% were women. The median follow-up period was 4.9 years. Seventy-nine patients (86.8%) showed fibrotic progression with persistent areas of mosaic attenuation, finally replaced by fibrosis, and 20 (22.0%) developed AE. Baseline fibrosis score and CT pattern of usual interstitial pneumonia (UIP)/probable UIP were independent risk factors for predicting fibrotic progression (hazard ratio [HR] = 1.05, 95% confidence interval [CI] = 1.02-1.09, p < 0.001, for fibrosis score; HR = 2.50, CI = 1.50-4.16, p < 0.001, for CT pattern) and AEs (HR = 1.07, CI = 1.01-1.13, p = 0.019, for fibrosis score; HR = 5.47, CI = 1.23-24.45, p = 0.026, for CT pattern) after adjusting clinical covariables. CONCLUSION:Fibrotic progression and AE were identified in 86.8% and 22.0% of patients with chronic HP. Fibrosis score and CT pattern of UIP/probable UIP on baseline chest CT may predict fibrotic progression and AE. KEY POINTS:• Most patients (87%) showed fibrotic progression on long-term follow-up with persistent areas of mosaic attenuation that were finally replaced by fibrosis at a later stage. • One-fifth of patients (22%) experienced acute exacerbation associated with worse prognosis. • Fibrosis score (sum of reticulation and honeycombing) and CT pattern of UIP/probable UIP on baseline CT were independent predictors for predicting fibrotic progression and acute exacerbation.
journal_name
Eur Radioljournal_title
European radiologyauthors
Choe J,Chae EJ,Kim YJ,Do KH,Song JS,Song JWdoi
10.1007/s00330-020-07469-2subject
Has Abstractpub_date
2020-11-25 00:00:00eissn
0938-7994issn
1432-1084pii
10.1007/s00330-020-07469-2pub_type
杂志文章abstract:OBJECTIVES:To predict the primary neuroendocrine tumour of the gastrointestinal tract site based on observed metastatic sites. METHODS:We studied data from the radiology database of a single, large cancer centre on 250 patients with pathologically confirmed neuroendocrine tumours. Primary tumour sites and the location...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2615-y
更新日期:2013-02-01 00:00:00
abstract::To investigate the influence of age, sex and spinal level on perfusion parameters of normal lumbar bone marrow with dynamic contrast-enhanced MRI (DCE MRI). Sixty-seven subjects referred for evaluation of low back pain or sciatica underwent DCE MRI of the lumbar spine. After subtraction of dynamic images, a region of ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-0943-8
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abstract::The goal of this study was to analyze the diagnostic value of three-dimensional time-of-flight magnetic resonance angiography (3D TOF MRA), performed on a 0.5-T system in the detection of neurovascular compression in patients with trigeminal neuralgia (TN). One hundred seventy-two TN patients were examined using plain...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000596
更新日期:2001-01-01 00:00:00
abstract::This pictorial review illustrates the anatomical features of normal intra-articular components of the hip and their common disorders on MR arthrography. On T1-weighted MR arthrograms, the normal contrast-filled joint cavity shows a homogeneous high signal intensity. Normal acetabular labrum appears as a well-delineate...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300050009
更新日期:2000-01-01 00:00:00
abstract::To evaluate the efficiency of laser thermocoagulation under computed tomography (CT) guidance in the treatment of osteoid osteoma within a strictly pediatric group. Twenty-five patients aged 4 to 17 years were treated under CT by laser thermocoagulation. The nidus measured on average 10.1 mm. Pain relief was the main ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-1173-9
更新日期:2009-03-01 00:00:00
abstract::Ovarian cancer is the most lethal among the gynecologic malignancies with approximately 70% of patients presenting with advanced tumor stage. The prognosis of patients with ovarian cancer is directly related to the tumor stage and residual tumor burden after cytoreductive surgery. Exploratory laparotomy has been the c...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-007-0736-5
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVES:To determine whether there is a difference in frequency and clinical relevance of incidental findings detected by total-body computed tomography scanning (TBCT) compared to those by the standard work-up (STWU) with selective computed tomography (CT) scanning. METHODS:Trauma patients from five trauma centres...
journal_title:European radiology
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2017-06-01 00:00:00
abstract::Typical MRI findings for gastro-intestinal stromal tumours (GIST) under treatment with imatinib were evaluated. MRI was performed in 45 patients (25 responders, 20 non-responders) with metastatic or locally advanced, unresectable GIST. Target lesions were selected and re-evaluated after 2, 4, and 6 months of therapy w...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-005-2867-x
更新日期:2005-12-01 00:00:00
abstract::The aim of this study was to evaluate the value of automatic bolus tracking for monophasic spiral CT of the liver and to assess the liver-to-lesion conspicuity in comparison with time-delay examinations. In 40 patients scheduled for therapy control of known hypovascular hepatic metastases a monophasic spiral CT was co...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000637
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the risk factors affecting early diffuse recurrence within 1 year of percutaneous ultrasound-guided radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC). METHODS:Out of 146 patients who received transcatheter arterial chemoembolisation (TACE) for treatment of recurrent HCC after percu...
journal_title:European radiology
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更新日期:2013-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
abstract::The aim of this study was to determine apparent diffusion coefficients (ADCs) of focal liver lesions on the basis of a respiratory triggered diffusion-weighted single-shot echo-planar MR imaging sequence (DW-SS-EPI) and to evaluate whether ADC measurements can be used to characterize lesions. One hundred and two patie...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-007-0785-9
更新日期:2008-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2005-06-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5616-7
更新日期:2019-02-01 00:00:00
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doi:10.1007/s00330-014-3271-1
更新日期:2014-10-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-3595-5
更新日期:2015-07-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300000543
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:This study aimed to evaluate automated breast ultrasound (ABUS) compared to hand-held traditional ultrasound (HHUS) in the visualisation and BIRADS characterisation of breast lesions. MATERIALS AND METHODS:From January 2016 to January 2017, 1,886 women with breast density category C or D (aged 48.6±10.8 yea...
journal_title:European radiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00330-017-5011-9
更新日期:2018-02-01 00:00:00
abstract::Vertebral fractures are the hallmark of osteoporosis and are associated with increased morbility and mortality. Because a majority of vertebral fractures often occur in absence of specific trauma and are asymptomatic, their identification is radiographic. The two most widely used methods to determine the severity of v...
journal_title:European radiology
pub_type: 杂志文章,评审
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更新日期:2008-07-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1566-0
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:To evaluate magnetic resonance imaging (MRI) for diaphragmatic endometriosis diagnosis. MATERIALS AND METHODS:Over a 2-year period, all diaphragmatic MRI performed in the context of diaphragmatic endometriosis were reviewed. Axial and coronal fat-suppressed T1- and T2-weighted sequences were analyzed by two in...
journal_title:European radiology
pub_type: 杂志文章
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更新日期:2016-11-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2452-8
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVES:To evaluate the changes in mammographic density after tamoxifen discontinuation in premenopausal women with oestrogen receptor-positive breast cancers and the underlying factors METHODS: A total of 213 consecutive premenopausal women with breast cancer who received tamoxifen treatment after curative surgery ...
journal_title:European radiology
pub_type: 杂志文章
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更新日期:2018-08-01 00:00:00
abstract::Carcinoid heart disease is a frequent complication of the carcinoid syndrome, usually presenting as right-sided valvular heart disease. Although the diagnosis is most often made with cardiac ultrasound, MRI and CT are valuable techniques for diagnosing carcinoid heart disease. ...
journal_title:European radiology
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract:OBJECTIVES:Radiomic involves testing the associations of a large number of quantitative imaging features with clinical characteristics. Our aim was to extract a radiomic signature from axial T2-weighted (T2-W) magnetic resonance imaging (MRI) of the whole prostate able to predict oncological and radiological scores in ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07105-z
更新日期:2021-02-01 00:00:00
abstract::At present, medical applications applying World Wide Web (WWW) technology are mainly used to view static images and to retrieve some information. The Java platform is a relative new way of computing, especially designed for network computing and distributed applications which enables interactive connection between use...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000432
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:The complexity of anatomical structure within the breast represents the ultimate limit to signal detection on a mammogram. To increase lesion conspicuity Digital Breast Tomosynthesis (DBT) has been recently proposed and several manufacturers are currently performing clinical trials. In this study we investiga...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-2041-y
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:To evaluate a pumping emulsification device that can improve the physiochemical properties and stability of lipiodol emulsion for conventional transarterial chemoembolization. MATERIALS AND METHODS:A pumping emulsification device constructed of a glass membrane with a hydrophobic surface with pore size of 50 μ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-5197-x
更新日期:2018-05-01 00:00:00
abstract::Magnetic resonance (MR) arthrography has gained increasing popularity as a diagnostic tool in the assessment of intra-articular derangements. Its role has been studied extensively in the shoulder, but it also has been explored in the hip, elbow, knee, wrist and ankle. This article reviews the current role of direct MR...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-004-2449-3
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVES:To investigate the feasibility of a newly developed noise reduction technique at coronary CT angiography (CTA) that uses multi-phase data-averaging and non-rigid image registration. METHODS:Sixty-five patients underwent coronary CTA with prospective ECG-triggering. The range of the phase window was set at 7...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3381-9
更新日期:2015-01-01 00:00:00