Analyses of circRNA and mRNA profiles in the submandibular gland in hypertension.

abstract：:Fluorescence in situ hybridization was used to establish the order of, and to estimate genomic distances among, members of the carcinoembryonic antigen (CEA) and pregnancy-specific glycoprotein (PSG) subgroups on chromosome 19. Fluorescence in situ hybridization to metaphase chromosomes localized the PSG subgroup telo...

journal_title：Genomics

authors： Brandriff BF,Gordon LA,Tynan KT,Olsen AS,Mohrenweiser HW,Fertitta A,Carrano AV,Trask BJ

更新日期：1992-04-01 00:00:00

abstract：:Palmitoyl-protein thioesterase (PPT) is a small glycoprotein that removes palmitate groups from cysteine residues in lipid-modified proteins. We recently reported mutations in PPT in patients with infantile neuronal ceroid lipofuscinosis (INCL), a severe neurodegenerative disorder (J. Vesa et al., 1995, Nature 376: 58...

journal_title：Genomics

authors： Schriner JE,Yi W,Hofmann SL

更新日期：1996-06-15 00:00:00

abstract：:The murine arylsulfatase A (ARSA) gene and cDNA have been cloned and sequenced. The gene is 3.8 kb long and contains eight exons. All intron/exon splice junctions conform to the GT/AG consensus sequence. The genomic structure is similar to that of the human gene. One major RNA species of 3.2 kb is transcribed. This RN...

journal_title：Genomics

authors： Kreysing J,Polten A,Hess B,von Figura K,Menz K,Steiner F,Gieselmann V

更新日期：1994-01-15 00:00:00

abstract：:The human HYAL2 gene encodes a lysosomal hyaluronidase that is related to the testicular PH-20 hyaluronidase. Regions conserved in these proteins have been used to design PCR primers suitable for the isolation of a fragment of the murine Hyal2 gene. This fragment was used to isolate the Hyal2 cDNA from a cDNA library....

journal_title：Genomics

authors： Strobl B,Wechselberger C,Beier DR,Lepperdinger G

更新日期：1998-10-15 00:00:00

abstract：:Here, we report the genomic features and the bioremediation potential of Halomonas desertis G11, a new halophilic species which uses crude oil as a carbon and energy source and displays intrinsic resistance to salt stress conditions (optimum growth at 10% NaCl). G11 genome (3.96 Mb) had a mean GC content of 57.82%, 36...

journal_title：Genomics

authors： Neifar M,Chouchane H,Najjari A,El Hidri D,Mahjoubi M,Ghedira K,Naili F,Soufi L,Raddadi N,Sghaier H,Ouzari HI,Masmoudi AS,Cherif A

更新日期：2019-12-01 00:00:00

abstract：:The human IGH constant region spans 350 kb and includes nine genes and two pseudogenes. All of the constant region gene cluster has been cloned except for sequences between the IGHD and IGHG3 genes, between the IGHA1 and IGHG2 genes, and the 3' region downstream of the IGHA2 gene. The regions 3' of the IGHA genes, whi...

journal_title：Genomics

authors： Kang HK,Cox DW

更新日期：1996-07-01 00:00:00

abstract：:A genetic linkage study of the RFLPs identified by nine DNA probes localized to the pericentromeric region and long arm of chromosome 17 has been undertaken in 16 families with von Recklinghausen neurofibromatosis (NF1). Close linkage has been shown with the markers CRI-L946 (D17S36), CRI-L581 (D17S37), p17H8 (D17Z1),...

journal_title：Genomics

authors： Upadhyaya M,Sarfarazi M,Huson SM,Stephens K,Broadhead W,Harper PS

更新日期：1987-12-01 00:00:00

abstract：:Sulfonation is an important pathway in the biotransformation of many drugs, xenobiotics, neurotransmitters, and steroid hormones. The thermostable (TS) form of phenol sulfotransferase (PST) preferentially catalyzes the sulfonation of "simple" planar phenols, and levels of activity of TS PST in human tissues are contro...

journal_title：Genomics

authors： Her C,Raftogianis R,Weinshilboum RM

更新日期：1996-05-01 00:00:00

abstract：:The gene encoding the human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R1) was mapped to chromosome 7 by PCR analysis of genomic DNA from a human/rodent somatic cell hybrid mapping panel. This assignment was confirmed and the gene localized to chromosome band 7p14 by fluorescence in sit...

journal_title：Genomics

authors： Stoffel M,Espinosa R 3rd,Trabb JB,Le Beau MM,Bell GI

更新日期：1994-10-01 00:00:00

abstract：:Glutaredoxin is a small protein (12 kDa) catalyzing glutathione-dependent disulfide oxidoreduction reactions in a coupled system with NADPH, GSH, and glutathione reductase. A cDNA encoding the human glutaredoxin gene (HGMW-approved symbol GLRX) has recently been isolated and cloned from a human fetal spleen cDNA libra...

journal_title：Genomics

authors： Padilla CA,Bajalica S,Lagercrantz J,Holmgren A

更新日期：1996-03-15 00:00:00

abstract：:The closely linked proline-rich protein (Prp) genes, coding for abundant salivary proteins, are located on distal mouse chromosome 6. They are part of a conserved linkage group that is represented on human chromosome 12p. Two other markers, Ea-10 and Es-12, that were previously unassigned to a chromosome are closely l...

journal_title：Genomics

authors： Azen EA,Davisson MT,Cherry M,Taylor BA

更新日期：1989-10-01 00:00:00

abstract：:A cDNA encoding the human GABAA receptor beta 3 subunit has been isolated from a brain cDNA library and its nucleotide sequence has been determined. This gene, GABRB3, has recently been mapped to human chromosome 15q11q13, the region deleted in Angelman and Prader-Willi syndromes. The association of distinct phenotype...

journal_title：Genomics

authors： Wagstaff J,Chaillet JR,Lalande M

更新日期：1991-12-01 00:00:00

abstract：:We report a comparative map of canine chromosome 1 (CFA1) incorporating single nucleotide polymorphisms (SNPs) and insertion/deletion (indel) polymorphisms, developed by using cross-species primers, radiation hybrid analysis, and pool-and-sequence identification of genetic variations. Fifty-five genes were chosen with...

journal_title：Genomics

authors： Housley DJ,Ritzert E,Venta PJ

更新日期：2004-08-01 00:00:00

abstract：:Changing bovine milk fatty acid (FA) composition through selection can decrease saturated FA (SFA) consumption, improve human health and provide a means for manipulating processing properties of milk. Our study determined associations between milk FA composition and genes from triacylglycerol (TAG) biosynthesis pathwa...

journal_title：Genomics

authors： Nafikov RA,Schoonmaker JP,Korn KT,Noack K,Garrick DJ,Koehler KJ,Minick-Bormann J,Reecy JM,Spurlock DE,Beitz DC

更新日期：2014-12-01 00:00:00

abstract：:By optimizing the primer-annealing temperature in a rapid air cycling procedure, two human DNA sequences encoding centromere proteins B and C (CENP-B and CENP-C) were specifically amplified without any detectable amplification of highly homologous rodent DNA sequences. Using a panel of rodent/human hybrid DNA, the gen...

journal_title：Genomics

authors： Sugimoto K,Yata H,Himeno M

更新日期：1993-07-01 00:00:00

abstract：:Laboratory mouse strains are known to have emerged from recent interbreeding between individuals of Mus musculus isolated populations. As a result of this breeding history, the collection of polymorphisms observed between laboratory mouse strains is likely to harbor the effects of natural selection between reproductiv...

journal_title：Genomics

authors： Reuveni E,Birney E,Gross CT

更新日期：2010-04-01 00:00:00

abstract：:Given the vast amount of genomic data, alignment-free sequence comparison methods are required due to their low computational complexity. k-mer based methods can improve comparison accuracy by extracting an effective feature of the genome sequences. The aim of this paper is to extract k-mer intervals of a sequence as ...

journal_title：Genomics

authors： Han GB,Cho DH

更新日期：2019-12-01 00:00:00

abstract：:Syndactyly in Holstein cattle is an autosomal recessive abnormality characterized by the fusion of the functional digits. This disorder has been previously mapped to the telomeric part of bovine chromosome 15. Here, we describe the fine-mapping of syndactyly in Holstein cattle to a 3.5-Mb critical interval using a com...

journal_title：Genomics

authors： Duchesne A,Gautier M,Chadi S,Grohs C,Floriot S,Gallard Y,Caste G,Ducos A,Eggen A

更新日期：2006-11-01 00:00:00

abstract：:Small-scale changes in gene order and orientation are common in plant genomes, even across relatively short evolutionary distances. We investigated the association of retrotransposons in and near rice gene pairs with gene pair conservation, inversion, rearrangement, and deletion in sorghum, maize, and Brachypodium. Co...

journal_title：Genomics

authors： Krom N,Ramakrishna W

更新日期：2012-05-01 00:00:00

abstract：:Cardiac hypertrophy is an important risk factor for cardiac morbidity and mortality. To unravel the underlying pathogenic genetic pathways, we hybridized left ventricular RNA from Transverse Aortic Constriction mice at 48 h, 1 week, and 2, 3, and 8 weeks after surgery to microarrays containing a 15K fetal cDNA collect...

journal_title：Genomics

authors： van den Bosch BJ,Lindsey PJ,van den Burg CM,van der Vlies SA,Lips DJ,van der Vusse GJ,Ayoubi TA,Doevendans PA,Smeets HJ

更新日期：2006-10-01 00:00:00

abstract：:The chromosomal localization of the human Mu class glutathione S-transferase (GST) genes has been complicated by two factors; the total number of genes is unknown and there is a polymorphism that results from the presence or absence of the GSTM1 gene. Three human Mu class glutathione S-transferase isoenzymes, GSTM1, G...

journal_title：Genomics

authors： Ross VL,Board PG,Webb GC

更新日期：1993-10-01 00:00:00

abstract：:High liver iron content is a risk factor for developing hepatocellular carcinoma (HCC). However, HCC cells are always iron-poor. Therefore, an association between hepatocyte iron storage capacity and differentiation is suggested. To characterize biological processes involved in iron loading capacity, we used a cDNA mi...

journal_title：Genomics

authors： Troadec MB,Glaise D,Lamirault G,Le Cunff M,Guérin E,Le Meur N,Détivaud L,Zindy P,Leroyer P,Guisle I,Duval H,Gripon P,Théret N,Boudjema K,Guguen-Guillouzo C,Brissot P,Léger JJ,Loréal O

更新日期：2006-01-01 00:00:00

abstract：:WRKY proteins constitute a large family of transcription factors. In this study, we identified 81 WRKY genes (named HbWRKY1 to HbWRKY81) in the latest rubber tree genome. Tissue-specific expression profiles showed that 74 HbWRKYs were expressed in at least one of the tissues and the other 7 genes showed very low expre...

journal_title：Genomics

authors： Li HL,Guo D,Yang ZP,Tang X,Peng SQ

更新日期：2014-07-01 00:00:00

abstract：:Four highly conserved members of the skeletal protein 4.1 gene family encode a diverse array of protein isoforms via tissue-specific transcription and developmentally regulated alternative pre-mRNA splicing. In addition to the prototypical red blood cell 4.1R (human gene symbol EPB41,) these include two homologues tha...

journal_title：Genomics

authors： Peters LL,Weier HU,Walensky LD,Snyder SH,Parra M,Mohandas N,Conboy JG

更新日期：1998-12-01 00:00:00

abstract：:Several neuropsychiatric disorders map to human 15q13-q14, which contains a strong candidate in the alpha7-nicotinic acetylcholine receptor subunit gene (CHRNA7) and is partly duplicated, complicating further genetic analysis. We have shown that the partial duplication is in a hybrid (CHRFAM7A)between CHRNA7 and one o...

journal_title：Genomics

authors： Riley B,Williamson M,Collier D,Wilkie H,Makoff A

更新日期：2002-02-01 00:00:00

abstract：:We have isolated and sequenced part of a new gene of the tyrosine kinase family. This gene, called FLT3, has strong sequence similarities with members of a group of genes encoding growth factor receptors: FMS, KIT, and PDGFR. We have localized the human FLT3 gene to chromosome 13, band q12, and its mouse homolog to ch...

journal_title：Genomics

authors： Rosnet O,Matteï MG,Marchetto S,Birnbaum D

更新日期：1991-02-01 00:00:00

abstract：:Several studies have reported significant linkage for schizophrenia on 6p23, with a maximum lod score between D6S274 and D6S285. In this paper, we present a new human kinesin gene localized in this 2-cM interval. This gene, termed KIF13A, belongs to the unc-104/KIF1A kinesin subfamily and represents the orthologue of ...

journal_title：Genomics

authors： Jamain S,Quach H,Fellous M,Bourgeron T

更新日期：2001-05-15 00:00:00

abstract：:We have reported that a novel c-Myc binding protein, AMY-1, stimulated the transcription activity of c-Myc and was translocated from the cytoplasm to the nucleus in a c-Myc-dependent manner. AMY-1 works as an inducer of human K562 cell differentiation upon induction of AraC. To characterize the expression or functiona...

journal_title：Genomics

authors： Furusawa M,Taira T,Iguchi-Ariga SM,Ariga H

更新日期：2003-02-01 00:00:00

abstract：:The alpha 1 subunit genes encoding voltage-dependent Ca2+ channels are members of a gene family. We have used human brain cDNA probes to localize the neuronal isoform genes CACNL1A4 (alpha 1A), CACNL1A5 (alpha 1B), and CACNL1A6 (alpha 1E) to 19p13, 9q34, and 1q25-q31, respectively, using fluorescence in situ hybridiza...

journal_title：Genomics

authors： Diriong S,Lory P,Williams ME,Ellis SB,Harpold MM,Taviaux S

更新日期：1995-12-10 00:00:00

abstract：:The secretome refers to all the Excreted/Secreted (ES) proteins of a cell, and these are involved in critical biological processes, such as cell-cell communication, and host immune responses. Recently, we introduced the Abundance of Antigenic Aegions (AAR) value to assess the protein antigenic density and to evaluate ...

journal_title：Genomics

authors： Cornejo-Granados F,Hurtado-Ramírez JM,Hernández-Pando R,Ochoa-Leyva A

更新日期：2019-12-01 00:00:00