Communication between microorganisms as a basis for production of virulence factors.

Abstract:

:Quorum sensing (QS), or cell-to-cell communication in bacteria, is achieved through the production and subsequent response to the accumulation of extracellular signal molecules called autoinductors. The main role of QS is regulation of production of virulence factors in bacteria. Bacterial pathogenicity is often manifested by the expression of various cell-associated and secreted virulence factors, such as exoenzymes, toxins and biofilm. In bacteria, the expression of virulence factors is controlled coordinately by the global regulatory QS systems, which includes the AI-1/LuxIR-, AI-2/LuxS-, AI-3/QsC-, AIP/Agr-based systems. The regulation of production of virulence factors is extremely complex and many components influence it.

journal_name

Pol J Microbiol

authors

Gospodarek E,Bogiel T,Zalas-Wiecek P

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

191-8

issue

3

eissn

1733-1331

issn

2544-4646

journal_volume

58

pub_type

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