Neonatal seizures: an update on mechanisms and management.

abstract：:Administrative data research on maternal racial disparities supports 2 broad clinical inferences. First, failure to rescue in terms of both death and severe maternal morbidity likely accounts for a significant proportion of maternal disparities. Second, risk for adverse outcomes by race is generally differential with ...

journal_title：Clinics in perinatology

authors： Friedman A

更新日期：2020-12-01 00:00:00

abstract：:Because of the high frequency, serious sequelae, and complex and costly management, neonatal jaundice is a good candidate for preventive treatment. In this respect the clinical problem of neonatal jaundice has many similarities with the problem of hemorrhagic disease of the newborn. Both conditions are transient pecul...

journal_title：Clinics in perinatology

authors： Valaes TN,Harvey-Wilkes K

更新日期：1990-06-01 00:00:00

abstract：:Although it has been customary to treat neonatal jaundice at lower serum bilirubin levels in low-birth weight infants than in term infants, the threshold bilirubin levels and long-term benefits for early treatment of preterm infants have not been validated. This article summarizes and evaluates existing evidence and s...

journal_title：Clinics in perinatology

authors： Cashore WJ

更新日期：2000-03-01 00:00:00

abstract：:The placenta not only "records" and reflects the intrauterine environment, it also provides valuable information on the cause and timing of many adverse events and conditions. The placenta may be useful in several ways. It may be the cause of injury due to an inherent abnormality, it may "malfunction" because of disea...

journal_title：Clinics in perinatology

authors： Baergen RN

更新日期：2007-09-01 00:00:00

abstract：:We have learned from prenatal diagnosis that there is a wide spectrum of clinical severity for fetuses that have a lung mass. Accurate prognostic information is necessary for providing appropriate management and parental counseling. If an associated life-threatening anomaly is present or if the mother is ill with the ...

journal_title：Clinics in perinatology

authors： Adzick NS

更新日期：2003-09-01 00:00:00

abstract：:Beta-sympathomimetic agents are used extensively in obstetrics to inhibit premature labor. Knowledge of the pharmacology, mode of action on smooth muscle, and cardiovascular and metabolic side effects of these agents is essential for the obstetrician and perinatologist. This review article draws extensively on recent ...

journal_title：Clinics in perinatology

authors： Nuwayhid B,Rajabi M

更新日期：1987-12-01 00:00:00

abstract：:The newborn infant's skin is not a complete barrier to the absorption of externally applied agents, particularly if it is damaged, diseased, or immature. Immaturity is the most important factor that determines percutaneous absorption. Very immature infants in the early neonatal period have a poorly developed epidermis...

journal_title：Clinics in perinatology

authors： Rutter N

更新日期：1987-12-01 00:00:00

abstract：:Complex biochemical consequences are the result of a series of secondary biochemical changes caused by oxygen depletion. Hypoxia in the fetus and neonate results in decreased GI blood flow, especially to the GI mucosa. Although severe O2 deprivation cannot be entirely compensated for, an increase in tissue O2 extracti...

journal_title：Clinics in perinatology

authors： Goplerud JM,Delivoria-Papadopoulos M

更新日期：1986-03-01 00:00:00

abstract：:Diabetic pregnancies involve complex alterations in maternal-placental and fetal compartments. This article discusses the unique features of diabetic pregnancies as they pertain to the maternal changes that must occur to accommodate the fetus. ...

journal_title：Clinics in perinatology

authors： Hollingsworth DR

更新日期：1983-10-01 00:00:00

abstract：:Advances in fetal echocardiography are providing highly accurate diagnoses of congenital heart disease prior to delivery, making it possible to plan the delivery-room management of these newborns. Knowledge of the expected transitional circulation occurring with birth and the pathophysiologic implications of congenita...

journal_title：Clinics in perinatology

authors： Johnson BA,Ades A

更新日期：2005-12-01 00:00:00

abstract：:Postpartum hemorrhage is an obstetric emergency that represents a major cause of maternal morbidity and mortality. With the recent rise in the cesarean delivery rate, prompt recognition and proper management at the time of cesarean delivery are becoming increasingly important for providers of obstetrics. Preparedness ...

journal_title：Clinics in perinatology

authors： Bonanno C,Gaddipati S

更新日期：2008-09-01 00:00:00

abstract：:Several limitations and controversies surround the definition of hypotension; however, it remains one of the most common problems faced by neonates. Approximately 15% to 30% of neonates with hypotension fail to respond to volume and/or vasopressor or inotropes. They are considered to have refractory hypotension. Altho...

journal_title：Clinics in perinatology

authors： Kumbhat N,Noori S

更新日期：2020-09-01 00:00:00

abstract：:Congenital lung lesions (CLLs) comprise a heterogeneous group of developmental and histologic entities often diagnosed on screening prenatal ultrasound. Most fetuses with CLL are asymptomatic at birth; however, the risk of malignancy and infection drives the decision to prophylactically resect these lesions. The autho...

journal_title：Clinics in perinatology

authors： Moyer J,Lee H,Vu L

更新日期：2017-12-01 00:00:00

abstract：:The Mothers' Milk Bank (MMB) of San Jose, CA, has provided banked human milk to clinicians and researchers since its founding in 1974. This article briefly acknowledges the many and varied reasons for the use of human milk. Its primary focus however, is to review the protocol followed by the MMB for collection, bankin...

journal_title：Clinics in perinatology

authors： Asquith MT,Pedrotti PW,Stevenson DK,Sunshine P

更新日期：1987-03-01 00:00:00

abstract：:Neonatal stress responses have been investigated only in recent years. Term neonates mount substantial hormonal and metabolic responses, which are distinct from those of adult patients. These responses can be altered significantly by the effects of prematurity, the effects of graded surgical stress, and the anesthetic...

journal_title：Clinics in perinatology

authors： Anand KJ

更新日期：1990-03-01 00:00:00

abstract：:Scientific study of prenatal drug exposure and child outcome began a period of substantial growth in the 1970s with a focus on exposure to opiates. By the mid-1980s, attention shifted to cocaine. Most of this research has involved cohort studies in which groups of children are followed up longitudinally from birth. Si...

journal_title：Clinics in perinatology

authors： Smeriglio VL,Wilcox HC

更新日期：1999-03-01 00:00:00

abstract：:There were approximately 2 million deaths worldwide from tuberculosis in 1997, 98% of them in developing countries. Factors implicated in the resurgence of tuberculosis in the United States in the late 80s and early 90s included increased immigration from countries with high prevalence, HIV infection, emergence of res...

journal_title：Clinics in perinatology

authors： Laibl VR,Sheffield JS

更新日期：2005-09-01 00:00:00

abstract：:Pulse oximetry, a noninvasive technique of measuring oxygen saturation continuously, is being used increasingly in the intensive care setting. This article provides information regarding physiologic basis and practical aspects of clinical usage of pulse oximetry in the neonate, both in medical and surgical units. ...

journal_title：Clinics in perinatology

authors： Dziedzic K,Vidyasagar D

更新日期：1989-03-01 00:00:00

abstract：:A regionalized system of perinatal care, which draws on the strengths of individual hospitals and corrects any weaknesses, can enhance the level of performance of the community hospital. Although the care of high risk infants takes priority in this system, concern is expressed that routine perinatal care should also r...

journal_title：Clinics in perinatology

authors： Brown JL

更新日期：1980-03-01 00:00:00

abstract：:New knowledge has accumulated in recent years making it prudent to ask questions regarding current oxygenation policies and guidelines. Because new-born resuscitation affects so many individuals, and because resuscitation procedures may have dramatic consequences on infant and child health, intensified discussion and ...

journal_title：Clinics in perinatology

authors： Saugstad OD

更新日期：2004-09-01 00:00:00

abstract：:Antepartum fetal surveillance with Doppler ultrasound of umbilical artery has shown significant diagnostic efficacy in identifying fetal compromise in pregnancies complicated with fetal growth restriction (FGR). Its effectiveness in decreasing perinatal mortality has been shown by randomized clinical trials (Level I e...

journal_title：Clinics in perinatology

authors： Maulik D,Mundy D,Heitmann E,Maulik D

更新日期：2011-03-01 00:00:00

abstract：:Total parenteral nutrition permits normal growth and development of the infant during the adaptive phase of the short bowel syndrome. Skilled nutritional support combined with a variety of medical and surgical manipulations facilitates survival of infants with as little as 15 to 20 cm of intestinal length. ...

journal_title：Clinics in perinatology

authors： Ziegler MM

更新日期：1986-03-01 00:00:00

abstract：:Most pharmacokinetic and biologic attributes of digitalis are age dependent. They are determined in great measure by the chemical structure of the specific cardiac glycoside being used. These effects differ in the intact normal circulation and in heart failure because of the altered autonomic nervous system and hormon...

journal_title：Clinics in perinatology

authors： Hastreiter AR,John EG,van der Horst RL

更新日期：1988-09-01 00:00:00

abstract：:For more than 100 years, three principles have guided the treatment of neonatal asphyxia: maintain body heat, free air passages of obstructions, and stimulate respiration by supplying air to the lungs for oxygenation of the blood. This article addresses the question of which gas, air or 100% oxygen, is best supplied t...

journal_title：Clinics in perinatology

authors： Richmond S,Goldsmith JP

更新日期：2006-03-01 00:00:00

abstract：:In the past, all women with a family history of breast or ovarian cancer were considered to be at increased risk of cancer themselves. The discovery of BRCA1 and BRCA2 demonstrated that susceptibility to breast and ovarian cancer can be inherited by women as a single-gene autosomal dominant disorder. For such women, e...

journal_title：Clinics in perinatology

authors： Frank TS,Critchfield GC

更新日期：2001-06-01 00:00:00

abstract：:The fetal environment is thus well suited for normal growth and development with oxygen availability exceeding oxidative needs. With impairments in blood gas exchange this excess oxygen acts as a "margin of safety," providing for the maintenance of oxidative metabolism through increases in fractional O2 extraction, al...

journal_title：Clinics in perinatology

authors： Richardson BS

更新日期：1989-09-01 00:00:00

abstract：:The signs and symptoms associated with necrotizing enterocolitis (NEC) and the common scenarios in which NEC is observed are described to help physicians appreciate the breadth of this illness and to aid in the identification and diagnosis of those affected. An outline for medical management of infants with NEC is pre...

journal_title：Clinics in perinatology

authors： Kanto WP Jr,Hunter JE,Stoll BJ

更新日期：1994-06-01 00:00:00

abstract：:It is clear that prostaglandins and related compounds are important in the physiology and pathophysiology of the perinatal pulmonary circulation. This article focuses on what is known about prostaglandin-related compounds (PRC) in the pulmonary circulation of the developing and newly born mammal. Also included is a di...

journal_title：Clinics in perinatology

authors： Philips JB 3rd,Lyrene RK

更新日期：1984-10-01 00:00:00

abstract：:Using the pregnant woman as a means to medicate her fetus represents a new and exciting therapeutic approach in clinical pharmacology. In years to come, we will see an increase in the use of the currently accepted fetal therapies and an increase in the number of therapies available to the caregiver or clinician aimed ...

journal_title：Clinics in perinatology

authors： Simone C,Derewlany LO,Koren G

更新日期：1994-09-01 00:00:00

abstract：:Necrotizing enterocolitis (NEC) is a multifactorial disorder that primarily affects premature infants. Human milk compared with formula reduces the incidence of NEC. Feeding practices do not increase the incidence of NEC in preterm infants. There is no evidence supporting continuous versus intermittent tube feedings i...

journal_title：Clinics in perinatology

authors： Ramani M,Ambalavanan N

更新日期：2013-03-01 00:00:00