Survival benefit of renal transplantation in octogenarians.

abstract：INTRODUCTION:A long-term prospective randomized trial evaluating alemtuzumab, a humanized anti-CD52 monoclonal antibody, in a predominantly non-Caucasian population has yet to be reported. METHODS:Ninety deceased donor (DD) first renal transplant recipients were randomized into three different antibody induction group...

journal_title：Clinical transplantation

authors： Ciancio G,Burke GW,Gaynor JJ,Roth D,Kupin W,Rosen A,Cordovilla T,Tueros L,Herrada E,Miller J

更新日期：2008-03-01 00:00:00

abstract：:The organ shortage is one of the major challenges in the field of organ transplantation, yet the percentage of kidneys procured and discarded prior to transplantation has continued to rise to twenty percent. The causes of organ discard are complex, yet an urgent need exists for collaborative efforts to maximize the ut...

journal_title：Clinical transplantation

authors： Cooper M,Formica R,Friedewald J,Hirose R,O'Connor K,Mohan S,Schold J,Axelrod D,Pastan S

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Conversion from calcineurin inhibitor (CI)-based maintenance immunosuppression to sirolimus (SRL)-based immunosuppression may be beneficial in selected renal transplant recipients. The purpose of this study was to evaluate the safety and efficacy of a daclizumab (DAC) bridge protocol in patients converted ...

journal_title：Clinical transplantation

authors： Sundberg AK,Rohr MS,Hartmann EL,Adams PL,Stratta RJ

更新日期：2004-01-01 00:00:00

abstract：:Kidney transplantation offers longer survival, less morbidity and lower costs than dialysis. It is also believed to improve quality of life. The aim of this study was to compare prospectively the perceived health status (PHS) of dialyzed patients on a waiting list with kidney transplant recipients after transplantatio...

journal_title：Clinical transplantation

authors： Rosenberger J,van Dijk JP,Prihodova L,Majernikova M,Nagyova I,Geckova AM,Roland R,van den Heuvel WJ,Groothoff JW

更新日期：2010-05-01 00:00:00

abstract：INTRODUCTION:A "new" fast track kidney allocation scheme (FTKAS) was implemented in the UK in 2012 for offering of previously declined kidneys. We evaluated the impact of the FTKAS in utilization of declined kidneys and outcome. METHODS:Adult renal transplant centers were surveyed. Overall utilization was evaluated us...

journal_title：Clinical transplantation

authors： White AD,Roberts H,Ecuyer C,Brady K,Pathak S,Clark B,Hostert LH,Attia MS,Wellberry-Smith M,Hudson A,Ahmad N

更新日期：2015-10-01 00:00:00

abstract：:In the general population, obesity is associated with an increased risk of developing hypertension (HTN), type 2 diabetes mellitus (DM), and end-stage renal disease (ESRD). Therefore, most transplant centers have a body mass index (BMI) threshold for accepting living kidney donors. But there have been no studies of po...

journal_title：Clinical transplantation

authors： Issa N,Sánchez OA,Kukla A,Riad SM,Berglund DM,Ibrahim HN,Matas AJ

更新日期：2018-09-01 00:00:00

abstract：INTRODUCTION:In 2006, model for end-stage liver disease (MELD)-based allocation was implemented in the Eurotransplant (ET) region. Sick patients, who in general require more resources, are prioritized. In this analysis, the effect of MELD on costs for liver transplantation (LTx) was assessed. METHODS:Total costs for L...

journal_title：Clinical transplantation

authors： Bruns H,Hillebrand N,Schneider T,Hinz U,Fischer L,Schmidt J,Goldschmidt AJ,Schemmer P

更新日期：2011-09-01 00:00:00

abstract：:The role of the liver biopsy for establishing a diagnosis of liver allograft rejection was investigated by examining under code 151 liver biopsies from 32 recipients and correlating the results with the clinical diagnosis determined by chart review. One-hundred-and-four biopsies were obtained to evaluate the cause of...

journal_title：Clinical transplantation

authors： Aran PP,Bissel MG,Whitington PF,Bostwick DG,Adamac T,Baker AL

更新日期：1993-10-01 00:00:00

abstract：:Kidney dysfunction is a recognized complication after non-renal solid organ transplantation, particularly after intestinal transplant. In our study, we reviewed data on 33 multivisceral transplant (MVT)- and 15 isolated small bowel (ISB)-transplant patients to determine risk factors for kidney dysfunction. Kidney func...

journal_title：Clinical transplantation

authors： Suzuki M,Mujtaba MA,Sharfuddin AA,Yaqub MS,Mishler DP,Faiz S,Vianna RM,Mangus RS,Tector JA,Taber TE

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To determine whether depressive symptoms predicted survival before and after lung transplantation. We hypothesized that depressive symptoms might predict survival of wait-listed patients, but would not predict survival post-transplant. METHODS:This was a prospective, longitudinal study. Participants complete...

journal_title：Clinical transplantation

authors： Evon DM,Burker EJ,Galanko JA,Dedert E,Egan TM

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Recent studies demonstrated safety and efficacy of heart transplantation (HT) from hepatitis C virus (HCV)-positive donors. We sought to evaluate the impact of HCV donor status on the outcomes of patients undergoing HT in the United States. METHODS:We analyzed a retrospective cohort of adult patients from t...

journal_title：Clinical transplantation

authors： Doulamis IP,Tzani A,Moustakidis S,Kampaktsis PN,Briasoulis A

更新日期：2021-01-08 00:00:00

abstract：:The long-term side effects of lifelong steroid immunosuppression are well documented, therefore, steroid withdrawal (SW) if safe would clearly be of benefit. From 1987-1996, 470 kidney transplants were performed at our institution. During this time period, steroid withdrawal was offered to a select group of patients (...

journal_title：Clinical transplantation

authors： Sanfey H,Haussman G,Isaacs I,Ishitani M,Lobo P,McCullough C,Pruett T

更新日期：1997-10-01 00:00:00

abstract：:Early measures of graft function are increasingly used to assess efficacy in clinical trials of kidney transplant immunosuppression. This study aimed to assess the variability and quality of reporting of these endpoints in contemporary trials. Data regarding renal function endpoints were extracted from 213 reports fro...

journal_title：Clinical transplantation

authors： Knight SR,Hussain S

更新日期：2016-12-01 00:00:00

abstract：:Endothelial cells (ECs) are involved in allograft rejection and are prime targets, but also key players. HLA antigens are the most prominent targets of alloantibodies in transplantation. Alloantibodies against other antigens such as ABO blood group antigens and non-HLA antigens could also be demonstrated. Alloantibodi...

journal_title：Clinical transplantation

authors： Yamaguchi Y

更新日期：2012-07-01 00:00:00

abstract：:Recent changes in Center for Medicare & Medicaid Services (CMS) condition for participation, using benchmark volume/outcomes requirements for certification, have been implemented. Consequently, the ability of a transplant center to assess its risk tolerance is important in successful management. An analysis of SRTR da...

journal_title：Clinical transplantation

authors： Johnson SR,Karp SJ,Curry MP,Barugel M,Rodrigue JR,Mandelbrot DA,Rogers CP,Hanto DW

更新日期：2012-05-01 00:00:00

abstract：INTRODUCTION:Aortoiliac pathology in kidney allograft recipients is not rare but treatment timing is controversial. As most publications on this topic are case reports its difficult to evaluate long-term outcomes of those clinical challenges. Herein we report long-term results of these procedures. METHODS:From 1970 to...

journal_title：Clinical transplantation

authors： Tsivian M,Neri F,Nardo B,Bertelli R,Cavallari G,Fuga G,Faenza A

更新日期：2009-03-01 00:00:00

abstract：:Splenic artery "steal" syndrome after orthotopic liver transplantation (OLT) is an important cause of graft dysfunction. Direct pressure measurement in the hepatic (HA) and radial artery (RA) may identify patients at risk allowing its prevention. This observational study compared radial and hepatic mean arterial press...

journal_title：Clinical transplantation

authors： Wojcicki M,Pakosz-Golanowska M,Lubikowski J,Post M,Jarosz K,Milkiewicz P

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:One severe side effect of calcineurin inhibitors (CNIs: such as cyclosporine [CsA] and tacrolimus [FK506]) is neurotoxicity. CNIs are substrates for CYP3A5 and P-glycoprotein (P-gp), encoded by ABCB1 gene. In the present study, we hypothesized that genetic variability in CYP3A5 and ABCB1 genes may be associa...

journal_title：Clinical transplantation

authors： Yanagimachi M,Naruto T,Tanoshima R,Kato H,Yokosuka T,Kajiwara R,Fujii H,Tanaka F,Goto H,Yagihashi T,Kosaki K,Yokota S

更新日期：2010-11-01 00:00:00

abstract：:The current pandemic SARS-CoV-2 has required an unusual allocation of resources that can negatively impact chronically ill patients and high-complexity procedures. Across the European Reference Network on Pediatric Transplantation (ERN TransplantChild), we conducted a survey to investigate the impact of the COVID-19 o...

journal_title：Clinical transplantation

authors： Doná D,Torres Canizales J,Benetti E,Cananzi M,De Corti F,Calore E,Hierro L,Ramos Boluda E,Melgosa Hijosa M,Garcia Guereta L,Pérez Martínez A,Barrios M,Costa Reis P,Teixeira A,Lopes MF,Kaliciński P,Branchereau S,Boyer O

更新日期：2020-10-01 00:00:00

abstract：:Although patients within a transplant program are awaiting or have received disease modifying or curative treatment, they are also facing advanced illness and the possibility of death. The involvement of specialized palliative care services for these patients may improve symptom management and facilitate advance care ...

journal_title：Clinical transplantation

authors： Wentlandt K,Dall'Osto A,Freeman N,Le LW,Kaya E,Ross H,Singer LG,Abbey S,Clarke H,Zimmermann C

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Mycobacterium tuberculosis (TB) is a common pathogen worldwide, and it may cause significant infection after solid organ transplantation (SOT). We reviewed all reported TB cases to provide an update on its epidemiology, clinical presentation, management, and outcome after SOT. METHODS:MEDLINE, EMBASE, and O...

journal_title：Clinical transplantation

authors： Abad CLR,Razonable RR

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Graft survival following solitary pancreas transplantation has traditionally lagged behind that of simultaneous pancreas-kidney transplants. Thymoglobulin (TMG), a polyclonal rabbit-derived antilymphocyte antibody was originally introduced as treatment for acute rejection of renal allografts. However, data r...

journal_title：Clinical transplantation

authors： Tan M,Cantarovich M,Mangel R,Paraskevas S,Fortier M,Metrakos P

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:With the aim to improve the inferior outcomes in elderly recipients of kidneys from elderly cadaver donors, we applied and investigated a therapeutic regimen consisting of calcineurin inhibitor (CNI)-free, mycophenolate mofetil (MMF)-based immunosuppressive (i.s.) induction/maintenance protocol. In this arti...

journal_title：Clinical transplantation

authors： Arbogast H,Hückelheim H,Schneeberger H,Illner WD,Tarabichi A,Fertmann J,Wimmer CD,Hillebrand GF,Mistry-Burchardi N,Thomae R,Acikgöz A,Land W

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:The purpose of our study was to evaluate the diagnostic value of serum galactomannan antigen (GM) testing combined with chest computed tomography (CT) of invasive pulmonary aspergillosis (IPA) in pediatric patients after hematopoietic stem cell transplantation. METHODS:A retrospective nested case-control stu...

journal_title：Clinical transplantation

authors： Qiu KY,Liao XY,Huang K,Xu HG,Li Y,Fang JP,Zhou DH

更新日期：2019-08-01 00:00:00

abstract：:Post-transplant lymphoproliferative disorder (PTLD) is a significant complication after pediatric heart transplantation (HT), occurring in 5%-15% of patients within 3 years. Data >3 years from HT are limited. We sought to describe the prevalence, risk factors, and outcomes of PTLD occurring late (>3 years) after pedia...

journal_title：Clinical transplantation

authors： West SC,Friedland-Little JM,Schowengerdt KO Jr,Naftel DC,Pruitt Freeze E,Smith KS,Urschel S,Michaels MG,Kirklin JK,Feingold B

更新日期：2019-05-01 00:00:00

abstract：:Endothelin-1 is a vasoconstrictor peptide released by the vascular endothelium by various chemical and mechanical factors. Cellular rejection is one of the most common complications following orthotopic liver transplantation, endotheliitis being its most specific and consistent histological feature. To assess the role...

journal_title：Clinical transplantation

authors： Fábrega E,Figols J,Dueñas C,Crespo J,Casafont F,Sanchez-Antolín G,de las Heras G,Amado JA,Pons-Romero F

更新日期：1997-02-01 00:00:00

abstract：:Mycophenolic acid (MPA) dose reduction is associated with increased risk of rejection and graft loss in renal transplantation. This analysis investigated the impact of MPA dose changes with enteric-coated mycophenolate sodium (EC-MPS) or mycophenolate mofetil (MMF) in de novo heart transplant recipients. In a 12-month...

journal_title：Clinical transplantation

authors： Segovia J,Gerosa G,Almenar L,Livi U,Viganò M,Arizón JM,Yonan N,Di Salvo TG,Renlund DG,Kobashigawa JA,ERL 2401 Study Group.

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Quantitative analysis of the Epstein-Barr virus (EBV) genome has been recently reported to be helpful for early identification of EBV viremia which could reduce the risk of post-transplantation lymphoproliferative disorder (PTLD). AIM:To demonstrate the significance of serial monitoring of EBV genome load b...

journal_title：Clinical transplantation

authors： Matsukura T,Yokoi A,Egawa H,Kudo T,Kawashima M,Hirata Y,Tanaka H,Kagajo K,Wada H,Tanaka K

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Liver ischaemia-reperfusion (I/R) occurs during resuscitation from haemorrhagic shock, hepatic transplantation and anatomic resection of the liver. This injury is associated with hepatocellular enzyme release and hepatocyte necrosis. The impact of chronic illnesses such as diabetes mellitus (DM) on hepatic I...

journal_title：Clinical transplantation

authors： Rogers H 3rd,Zibari GB,Roberts J,Turnage R,Lefer DJ

更新日期：2004-01-01 00:00:00

abstract：UNLABELLED:Enteric-coated mycophenolate sodium (MPS) has been developed to help circumvent the upper gastrointestinal side-effects of mycophenolic acid by facilitating drug release in the small intestine. Many questions regarding the side-effect profile of MPS remain. Therefore, the purpose of this study is to review a...

journal_title：Clinical transplantation

authors： Hardinger KL,Hebbar S,Bloomer T,Murillo D

更新日期：2008-09-01 00:00:00