Adverse drug reaction driven immunosuppressive drug manipulations: a single-center comparison of enteric-coated mycophenolate sodium vs. mycophenolate mofetil.

abstract：:Kidney transplant obstruction (KTO) following renal transplantation remains an important reversible cause of allograft dysfunction, requiring prompt diagnosis to prevent long-term graft damage. Although ultrasound can accurately diagnose renal transplant hydronephrosis, it cannot be used to assess its functional signi...

journal_title：Clinical transplantation

authors： Nankivell BJ,Cohn DA,Spicer ST,Evans SG,Chapman JR,Gruenewald SM

更新日期：2001-02-01 00:00:00

abstract：:A better understanding of the immunobiological processes and predictors of graft rejection holds promise for the development of potential therapeutic strategies and also individualization of immunosuppression. The objective of this study is to analyze the clinical relevance of immune parameters such as antidonor antih...

journal_title：Clinical transplantation

authors： Panigrahi A,Deka R,Bhowmik D,Dash SC,Tiwari SC,Guleria S,Mehta SN,Mehra NK

更新日期：2006-01-01 00:00:00

abstract：:Proven Pneumocystis carinii pneumonia (PCP) occurred in 8 (5.2%) of 154 adult liver transplant recipients between January 1986 and December 1992. The interval between transplantation and PCP ranged from 69 to 131 days with a mean of 95 days (SD 20 days). The PaO2 breathing room air at diagnosis ranged from 40 mmHg to ...

journal_title：Clinical transplantation

authors： Hayes MJ,Torzillo PJ,Sheil AG,McCaughan GW

更新日期：1994-12-01 00:00:00

abstract：:Calcineurin inhibitors (CNI) have been commonly used as pivotal immunosuppressive agents to renal transplant recipients and have contributed significantly to improving short-term allograft survival. However, long-term administration of CNI may cause an adverse effect on kidney function, known as chronic nephrotoxicity...

journal_title：Clinical transplantation

authors： Horike K,Takeda A,Yamaguchi Y,Ogiyama Y,Yamauchi Y,Murata M,Kawaguchi T,Suzuki T,Otsuka Y,Inaguma D,Goto N,Watarai Y,Uchida K,Morozumi K

更新日期：2011-07-01 00:00:00

abstract：:Post-transplant outcome of kidney allografts depends on various factors, one of which may be the compatibility in volume between graft and recipient. However, previous studies adjusted the graft volume only for recipient's size. As the adjusted graft volume for donor's size would be substituted of nephron number more ...

journal_title：Clinical transplantation

authors： Han SS,Yang SH,Oh YJ,Cho JY,Moon KC,Ha J,Kim YS

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:End-stage renal disease is associated with illness-induced disruptions that challenge patients and their families to accommodate and adapt. However, the impact of patients' marital status on kidney transplant outcome has never been studied. This project, based on data from United States Renal Data System (US...

journal_title：Clinical transplantation

authors： Naiman N,Baird BC,Isaacs RB,Koford JK,Habib AN,Wang BJ,Barenbaum LL,Goldfarb-Rumyantzev AS

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:A questionnaire study was designed to determine whether the quality of life benefit provided by receiving a kidney-pancreas (KP) transplant increased the incentive to return to work, compared with patients receiving a kidney alone (KA) transplant. METHODS:A confidential questionnaire was sent to 58 patients...

journal_title：Clinical transplantation

authors： Knight RJ,Daly L

更新日期：2004-02-01 00:00:00

abstract：:Lymphocyte cultures grown from liver allograft biopsies were shown to exhibit alloreactivity towards donor cells as measured by primed lymphocyte testing (PLT). The PLT specificity was determined in assays using HLA typed panel cells and/or by inhibition testing with HLA specific monoclonal antibodies. Certain culture...

journal_title：Clinical transplantation

authors： Markus BH,Demetris AJ,Saidman S,Fung JJ,Zeevi A,Starzl TE,Duquesnoy RJ

更新日期：1988-01-01 00:00:00

abstract：:These updated guidelines from the American Society of Transplantation Infectious Diseases Community of Practice address the prevention and management of Clostridium difficile infection in solid organ transplant (SOT) recipients. Clostridioides (formerly Clostridium) difficile infection (CDI) is among the most common h...

journal_title：Clinical transplantation

authors： Mullane KM,Dubberke ER,AST ID Community of Practice.

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Recent studies demonstrated safety and efficacy of heart transplantation (HT) from hepatitis C virus (HCV)-positive donors. We sought to evaluate the impact of HCV donor status on the outcomes of patients undergoing HT in the United States. METHODS:We analyzed a retrospective cohort of adult patients from t...

journal_title：Clinical transplantation

authors： Doulamis IP,Tzani A,Moustakidis S,Kampaktsis PN,Briasoulis A

更新日期：2021-01-08 00:00:00

abstract：:Coronary angiography (CA) is the gold standard evaluation of coronary artery disease in potential multi-organ donors. This use of iodinated contrast media could lead to contrast-induced acute kidney injury and consequently to delayed graft function (DGF). All patients in France who received a kidney from a 45-70-year-...

journal_title：Clinical transplantation

authors： Lesouhaitier M,Legeai C,Savoye E,Cantrelle C,Pipien I,Macher MA,Vigneau C,Dorent R

更新日期：2018-09-01 00:00:00

abstract：:Tacrolimus is the cornerstone of immunosuppressive therapy after kidney transplantation. Its narrow therapeutic window mandates serum level strict monitoring and dose adjustments to ensure the optimal risk-benefit balance. This observational retrospective study analyzed the effectiveness and safety of conversion from ...

journal_title：Clinical transplantation

authors： Sánchez Fructuoso A,Ruiz JC,Franco A,Diekmann F,Redondo D,Calviño J,Serra N,Aladrén MJ,Cigarrán S,Manonelles A,Ramos A,Gómez G,González Posada JM,Andrés A,Beneyto I,Muñiz AL,Perelló M,Lauzurica R

更新日期：2020-01-01 00:00:00

abstract：:The practice of uncontrolled donation after cardiac death (uDCD) has been met with tepid interest within the United States transplant community. Hesitancy stems largely from fears of eroding public trust due to complex ethical issues involving consent. Beyond ethical concerns, uDCD creates unique logistic challenges t...

journal_title：Clinical transplantation

authors： Choudhury RA,Prins K,Moore HB,Yoeli D,Kam A,Nydam TL

更新日期：2019-03-01 00:00:00

abstract：:We have developed a practical conditioning regimen without anti-thymocyte globulin (ATG), irradiation, or other myeloablative alkylating agent for low-income countries in which patients with severe aplastic anemia (SAA), who usually have heavily transfused and a prolonged disease history. The application of ATG, Busul...

journal_title：Clinical transplantation

authors： Wang SB,Li L,Pan XH,Hu DM,Peng LH,Liu L,Xie ZJ,Yin B,Sun XJ,Yu J,Liang Y

更新日期：2013-03-01 00:00:00

abstract：INTRODUCTION:Health-related quality of life (HRQOL) is severely impaired in advanced liver disease. The purpose of this study was to evaluate the impact of actual liver function and disease-specific factors on HRQOL of patients evaluated for liver transplantation. PATIENTS AND METHODS:Disease-specific QOL was analyzed...

journal_title：Clinical transplantation

authors： Jara M,Bednarsch J,Malinowski M,Lüttgert K,Orr J,Puhl G,Seehofer D,Neuhaus P,Stockmann M

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:As the indications for liver transplantation broaden to include older and more critically ill patients, the likelihood of encountering unsuspected cardiovascular disease increases. PURPOSE:This study examined the frequency, type, and subsequent outcome of intra- and postoperative cardiovascular complication...

journal_title：Clinical transplantation

authors： Dec GW,Kondo N,Farrell ML,Dienstag J,Cosimi AB,Semigran MJ

更新日期：1995-12-01 00:00:00

abstract：:As many as 50% of liver transplant patients suffer gastrointestinal (GI) disturbances post-transplant. Conversion from mycophenolate mofetil (MMF) to mycophenolate sodium (EC-MPS) alleviates GI symptom burden in renal transplant recipients. We employed a validated patient and physician-reported assessment to evaluate ...

journal_title：Clinical transplantation

authors： Toledo AH,Hendrix L,Buchholz V,Fisher E,Newton K,Smith C,Gerber DA

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:The average age of patients undergoing liver transplantation (LT) is consistently increasing. The aim of this case-control study is to evaluate survival and outcome of patients ≥65 yr compared to younger patients undergoing LT. MATERIALS AND METHODS:From 10/00 to 4/08 we performed 330 primary LT, 31 (9.4%...

journal_title：Clinical transplantation

authors： Montalti R,Rompianesi G,Di Benedetto F,Ballarin R,Gerring RC,Busani S,De Pietri L,De Ruvo N,Iemmolo RM,Guerrini GP,Smerieri N,Gerunda GE

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To clarify the predictive impact of expanded criteria for liver transplantation (LT) for patients with hepatocellular carcinoma (HCC) in 54 patients with HCC beyond the Milan criteria (MC) from a series of 109 consecutive living-related donor liver transplantation (LDLT) recipients with HCC. METHODS:Among 54...

journal_title：Clinical transplantation

authors： Shirabe K,Taketomi A,Morita K,Soejima Y,Uchiyama H,Kayashima H,Ninomiya M,Toshima T,Maehara Y

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:We aimed to develop an adapted information-motivation-behavioral skills (IMB) model to describe barriers and facilitators for adherence and self-management among kidney transplant recipients. METHODS:We conducted a review of literature about kidney transplant recipients' knowledge, perceptions, and experien...

journal_title：Clinical transplantation

authors： Ranahan M,Von Visger J,Kayler LK

更新日期：2020-06-01 00:00:00

abstract：:15-deoxyspergualin (DSG) is a novel immunosuppressant which has been shown to be effective in preventing and treating rejection in animal allo- and xenotransplant models. Preliminary clinical studies suggest that DSG is an effective antirejection agent. In our study, 4 patients with biopsy-proven rejection episodes th...

journal_title：Clinical transplantation

authors： Matas AJ,Gores PF,Kelley SL,Bielefield-Skrokov M,Kinaszczuk M,Gruessner RW,Najarian JS

更新日期：1994-04-01 00:00:00

abstract：:Sirolimus is an immunosuppressive agent increasingly used in cardiac transplant recipients in the setting of allograft vasculopathy or worsening renal function. Recently, sirolimus has been associated with increased risk of venous thromboembolism (VTE) in lung transplant recipients. To investigate whether this associa...

journal_title：Clinical transplantation

authors： Thibodeau JT,Mishkin JD,Patel PC,Kaiser PA,Ayers CR,Mammen PP,Markham DW,Ring WS,Peltz M,Drazner MH

更新日期：2012-11-01 00:00:00

abstract：:Research with human transplant recipients has shown that mycophenolate mofetil (MMF) is a powerful and selective immunosuppressant for maintenance therapy following renal transplantation. An additional body of work suggests that it might also be a valuable tool for arresting ongoing rejection episodes. One randomized,...

journal_title：Clinical transplantation

authors：

更新日期：1996-02-01 00:00:00

abstract：PURPOSE:Frail patients who undergo renal transplantation (RT) have more complications; however, little is known if these patients can sustain the wait to RT. We used the Timed Up and Go Test (TUGT) and Montreal Cognitive Assessment (MoCA) to determine outcomes of RT candidates. METHODS:In this retrospective study, 526...

journal_title：Clinical transplantation

authors： Bozhilov K,Vo KB,Wong LL

更新日期：2020-11-20 00:00:00

abstract：AIM:To explore the trends in the risk for rejection following heart transplantation (HT) over the past 25 years, and their relation to changes in medical management. METHODS:The study population comprised 216 HT patients. Rejection periods were defined as follows: 0-3 months (early), 3-12 months (intermediate), and 12...

journal_title：Clinical transplantation

authors： Katz M,Freimark D,Raichlin E,Har-Zahav Y,Arad M,Kassif Y,Peled A,Asher E,Elian D,Kogan A,Shlomo N,Ofek E,Lavee J,Goldenberg I,Peled Y

更新日期：2017-10-01 00:00:00

abstract：:Ten-year protocol biopsies were performed in 16 patients treated with calcineurin inhibitor (CNI) continuously. All kidney grafts were functioning well at the time of biopsy with the mean serum creatinine level of 1.6 +/- 0.8 mg/dL. The specimen of biopsy showed various degrees of tissue injury. According to the Banff...

journal_title：Clinical transplantation

authors： Okamoto M,Akioka K,Ushigome H,Higuchi A,Nobori S,Ogino S,Uryuhara K,Kaihara S,Hatta T,Urasaki K,Yoshimura N

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The Southeastern Kidney Transplant Coalition was created in 2010 to improve kidney transplant (KTx) rates in Georgia, North Carolina, and South Carolina. To identify dialysis staff-reported barriers to transplant, the Coalition developed a survey of dialysis providers in the region. METHODS:All dialysis uni...

journal_title：Clinical transplantation

authors： Browne T,Patzer RE,Gander J,Amamoo MA,Krisher J,Sauls L,Pastan S

更新日期：2016-04-01 00:00:00

abstract：:The study explores the prevalence of unrecognized diabetes mellitus (DM), the incidence and risk factors new onset diabetes mellitus (NODM) and determines whether patient survival differs between patients with transient (NODM that resolves) compared with those with fixed NODM. This is a single center review of solitar...

journal_title：Clinical transplantation

authors： Kiberd M,Panek R,Kiberd BA

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Abnormal mineral metabolism is not uncommon after renal transplant (TXP). In dialysis patients, elevated serum phosphorous (P), calcium (Ca), CaP product, and parathyroid hormone (PTH) are associated with increased morbidity and mortality. The effect of these abnormalities on recipient and graft survival aft...

journal_title：Clinical transplantation

authors： Egbuna OI,Taylor JG,Bushinsky DA,Zand MS

更新日期：2007-07-01 00:00:00

abstract：:Renal transplantation is presently the best treatment for end-stage renal disease, although considered contraindicated for elderly patients. However, more investigation is needed due to higher life expectancy rates of the general population and the increasing number of over 60-yr-old patients with chronic renal failur...

journal_title：Clinical transplantation

authors： Mendonça HM,Dos Reis MA,de Castro de Cintra Sesso R,Câmara NO,Pacheco-Silva A

更新日期：2007-11-01 00:00:00