Abstract：
:Renal transplantation is presently the best treatment for end-stage renal disease, although considered contraindicated for elderly patients. However, more investigation is needed due to higher life expectancy rates of the general population and the increasing number of over 60-yr-old patients with chronic renal failure dependent upon dialysis. This study aims to determine graft and patient survival rates of renal transplant patients 60 yr and older compared to a younger group (50-59 yr old). Relevant pre- and post-transplant clinical data related to graft and patient survival in both groups were also investigated. Three-hundred and twenty consecutive renal transplant patients were enrolled in this study and grouped based on age at the time of the transplantation: one-hundred and ten patients at or over 60 yr old (elderly group) and 210 patients ranging from 50 to 59 yr old (younger group). There were no statistical differences in either group regarding clinical characteristics and immunological risk factors. The incidence of acute rejection was higher in the younger group (37.6%) than in the elderly (22.7%) (p = 0.01). Censored to death graft survivals at five yr were respectively 86.7% for patients > or = 60 yr and 82.1% for patients 50-59 yr old (p = 0.49). Patient survival rates at five yr were respectively 76.2% for patients > or = 60 yr and 81.6% for patients 50-59 yr old (p = 0.33). Our data show that renal transplantation for elderly patients has similar results to those found in younger individuals, which does not make age, in and of itself, a contraindication for transplantation.
journal_name
Clin Transplantjournal_title
Clinical transplantationauthors
Mendonça HM,Dos Reis MA,de Castro de Cintra Sesso R,Câmara NO,Pacheco-Silva Adoi
10.1111/j.1399-0012.2007.00734.xsubject
Has Abstractpub_date
2007-11-01 00:00:00pages
755-60issue
6eissn
0902-0063issn
1399-0012pii
CTR734journal_volume
21pub_type
杂志文章abstract：BACKGROUND:It is unclear whether sirolimus, a newer immunosuppressive agent, widely used in renal transplantation, affects male sex hormone levels or sexual function. METHODS:Sex hormone profiles in male renal transplant recipients were obtained and compared between a sirolimus-treated group and a group not on sirolim...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2005.00257.x
更新日期：2005-04-01 00:00:00
abstract：:As fertility can be restored to normal soon after a kidney transplant, it is important for physicians caring for recipients to be able to inform the patient about the potential risks of pregnancy. Current opinion is that pregnancy can be successful if carried out under optimal circumstances, including stable allograft...
journal_title：Clinical transplantation
pub_type： 杂志文章,评审
doi：10.1111/j.1399-0012.2011.01492.x
更新日期：2011-11-01 00:00:00
abstract：:We examined the UNOS database from 7/15/00-7/17/05 for Regional deceased donor liver utilization. For each region, we performed logistic regression and derived odds ratios (OR) for donor characteristics associated with livers being transplanted outside of the region or not transplanted at all. Regions with smallest an...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2010.01214.x
更新日期：2011-01-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Vascular thrombosis is the most common cause of early graft loss after transplantation. Routine grayscale and Doppler ultrasound frequently fail to adequately visualize vascular compromise. Contrast-enhanced ultrasound is a novel approach to identifying these complications. METHODS:This was a pro...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/ctr.13733
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Invasive fungal infections (IFI) are associated with significant morbidity and mortality in lung transplant recipients (LTRs). However, data outlining use of echinocandins in prophylaxis and therapy of LTRs are limited. METHOD:A single-center retrospective cohort study on all LTRs from January-2010 to Decem...
journal_title：Clinical transplantation
pub_type： 临床试验,杂志文章
doi：10.1111/ctr.13437
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:We aimed to develop an adapted information-motivation-behavioral skills (IMB) model to describe barriers and facilitators for adherence and self-management among kidney transplant recipients. METHODS:We conducted a review of literature about kidney transplant recipients' knowledge, perceptions, and experien...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/ctr.13862
更新日期：2020-06-01 00:00:00
abstract：:Diabetic transplant recipients are at a high risk for foot pathology leading to amputation. This retrospective study from 1/85 to 2/95 examines the risk of foot complications in a population (n = 340) of diabetic renal and combined renal/pancreas transplant recipients. All groups suffered high lower extremity amputati...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：BACKGROUND:To assess the diagnostic value of magnetic resonance cholangiography (MRC) when evaluating biliary complications in a large series of liver transplants. METHODS:One hundred and twenty-nine patients prospectively underwent magnetic resonance (MR) imaging and MR cholangiography at 1.5-T device after orthotopi...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2009.01190.x
更新日期：2010-07-01 00:00:00
abstract：:The practice of uncontrolled donation after cardiac death (uDCD) has been met with tepid interest within the United States transplant community. Hesitancy stems largely from fears of eroding public trust due to complex ethical issues involving consent. Beyond ethical concerns, uDCD creates unique logistic challenges t...
journal_title：Clinical transplantation
pub_type： 杂志文章,评审
doi：10.1111/ctr.13474
更新日期：2019-03-01 00:00:00
abstract：:In Norway living kidney donors account for approximately 40% of all renal transplants. There is a shortage of information about how living kidney donors experience the donation process during the initial recovery from surgery. The aim of this study was to explore physical and psychosocial issues related to the experie...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2004.00304.x
更新日期：2005-02-01 00:00:00
abstract：:Endothelial cells (ECs) are involved in allograft rejection and are prime targets, but also key players. HLA antigens are the most prominent targets of alloantibodies in transplantation. Alloantibodies against other antigens such as ABO blood group antigens and non-HLA antigens could also be demonstrated. Alloantibodi...
journal_title：Clinical transplantation
pub_type： 杂志文章,评审
doi：10.1111/j.1399-0012.2012.01675.x
更新日期：2012-07-01 00:00:00
abstract：INTRODUCTION:In 2006, model for end-stage liver disease (MELD)-based allocation was implemented in the Eurotransplant (ET) region. Sick patients, who in general require more resources, are prioritized. In this analysis, the effect of MELD on costs for liver transplantation (LTx) was assessed. METHODS:Total costs for L...
journal_title：Clinical transplantation
pub_type： 临床试验,杂志文章
doi：10.1111/j.1399-0012.2011.01483.x
更新日期：2011-09-01 00:00:00
abstract：:Although many report intra-operative cardiac arrests (ICAs) in liver transplantation (LT), the incidence, major causes, and outcome remain unclear. We aimed to investigate retrospectively, the incidence, nature, and outcome of ICA in Asian population and to identify risk factors for ICA. Consecutive 1071 LTs in an ins...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/ctr.12085
更新日期：2013-03-01 00:00:00
abstract：:We sought to determine the incidence, risk factors, and consequences of acute rejection (AR) after conversion from a calcineurin inhibitor (CNI) to a proliferation signal inhibitor (PSI) in maintenance heart transplantation. Relevant clinical data were retrospectively obtained for 284 long-term heart transplant recipi...
journal_title：Clinical transplantation
pub_type： 杂志文章,多中心研究
doi：10.1111/ctr.12241
更新日期：2013-11-01 00:00:00
abstract：:Liver transplantation for hepatitis B virus (HBV)-related liver disease has changed from a contraindication to outcomes comparable with non-HBV-related liver transplantations during the last two decades. Mainly the implementation of immunoprophylaxis with hepatitis B immunoglobulin (HBIG) and the use of nucleoside ana...
journal_title：Clinical transplantation
pub_type： 杂志文章,评审
doi：10.1111/j.1399-0012.2006.00609.x
更新日期：2006-01-01 00:00:00
abstract：:Organ donor availability is the major limiting factor in pediatric liver transplantation, and many children succumb from their liver disease before a suitable donor can be found. In an attempt to overcome this shortage, reduced-size liver transplantation, split liver transplantation, and living-donor liver transplanta...
journal_title：Clinical transplantation
pub_type： 杂志文章,评审
doi：
更新日期：1991-04-01 00:00:00
abstract：BACKGROUND:Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) is an indication for orthotopic liver transplantation (OLT) in patients with tumor stage within the United Network for Organ Sharing criteria. The number of patients listed for HBV-related HCC is increasing, while the number of patients listed fo...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2010.01349.x
更新日期：2011-03-01 00:00:00
abstract：BACKGROUND:Chronic renal failure (CRF) is a common complication of calcineurin inhibitor (CNI)-based immunosuppression following cardiac transplantation (HTx). The aim of this prospective study was to evaluate the impact of an immunosuppressive conversion from CNIs to mycophenolate mofetil (MMF) and steroids in cardiac...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2008.00828.x
更新日期：2008-09-01 00:00:00
abstract：:The frequent scarcity of organ donors has made it necessary to consider transplantation of organs that may have the potential to transmit hepatitis B virus (HBV) to the recipient. Previous reports have documented the probability of infection of particular recipient populations with transplanted livers from hepatitis B...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:We analyzed the influence on allograft survival of pretransplant panel reactive antibodies (PRA) < 10%, PRA > 10%, autoantibodies, cold antibodies and a positive B cell crossmatch in 807 renal and 237 cardiac transplant recipients. Donors and recipients were predominantly of mixed ancestry (Khoi, San, Xhosa and Caucas...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：BACKGROUND:There have been no published data on use of the the newer immunosuppressants tacrolimus and mycophenolate mofetil (MMF) in high immunological risk renal transplantation. We therefore undertook a prospective study to systematically assess outcomes using these agents as part of an aggressive immunosuppressive ...
journal_title：Clinical transplantation
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1111/j.1399-0012.2005.00275.x
更新日期：2005-02-01 00:00:00
abstract：:Sauropus androgymus (SA), a vegetable of the Euphorbiaceae family, is a common food source in Malaysia. In Taiwan, over 30 patients have developed progressive respiratory failure after consuming the extract from raw SA leaves as a means of losing weight. Symptoms consistent with a severe obstructive ventilatory defect...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1034/j.1399-0012.1999.130610.x
更新日期：1999-12-01 00:00:00
abstract：:Ten-year protocol biopsies were performed in 16 patients treated with calcineurin inhibitor (CNI) continuously. All kidney grafts were functioning well at the time of biopsy with the mean serum creatinine level of 1.6 +/- 0.8 mg/dL. The specimen of biopsy showed various degrees of tissue injury. According to the Banff...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2006.00544.x
更新日期：2006-01-01 00:00:00
abstract：:A lack of research exploring post-transplant process optimization to reduce readmissions and increasing readmission rates at our center from 2009 to 2013 led to this study, aimed at assessing the effect of patient and process factors on 30-d readmission rates after kidney transplantation. This was a retrospective case...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/ctr.12748
更新日期：2016-07-01 00:00:00
abstract：:The transplantation of vascularized organs between species stimulates an intense rejection reaction by the recipient of the graft. The classification of the xenograft rejection reaction on the basis of the degree of genetic disparity between donor and recipient species and the presence or absence of preformed antibody...
journal_title：Clinical transplantation
pub_type： 杂志文章,评审
doi：
更新日期：1994-04-01 00:00:00
abstract：:Skin cancer is a common, potentially life-threatening malignancy in organ transplant recipients (OTR), and it is important for transplant physicians to be aware of patient history of skin cancer. Patient self-report represents a quick method of obtaining past medical history of skin cancer but no study has validated t...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2012.01601.x
更新日期：2012-03-01 00:00:00
abstract：:There is paucity in the data examining the differences in mycophenolate mofetil (MMF) dosing and outcomes among pediatric kidney transplant recipients (PKTX) between races. The aims of this study were as follows (i) to assess whether higher doses of MMF are being utilized in African American (AA) PKTX (ii) to determin...
journal_title：Clinical transplantation
pub_type： 临床试验,杂志文章
doi：10.1111/j.1399-0012.2010.01304.x
更新日期：2011-07-01 00:00:00
abstract：:We have experienced 5 hepatic vein stenoses in 3 children (8 to 23 months old) after living-related liver transplantation (total 48 liver transplants for 48 children between June 1990 and November 1992). The initial symptoms of hepatic vein stenosis were ascites and/or edema. The blood flow of hepatic vessels was mon...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:Clearance of hepatitis C virus (HCV) under antiviral therapy, including direct-acting antivirals (DAAs), has been associated with higher risk of rejection. Whether patients who are not on immunosuppression (IS) during DAA therapy are at higher risk of rejection is unknown. METHODS:Four transplant recipients...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/ctr.13303
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVE:To clarify the predictive impact of expanded criteria for liver transplantation (LT) for patients with hepatocellular carcinoma (HCC) in 54 patients with HCC beyond the Milan criteria (MC) from a series of 109 consecutive living-related donor liver transplantation (LDLT) recipients with HCC. METHODS:Among 54...
journal_title：Clinical transplantation
pub_type： 杂志文章
doi：10.1111/j.1399-0012.2011.01463.x
更新日期：2011-09-01 00:00:00
