Pilot evaluation of 15-deoxyspergualin for refractory acute renal transplant rejection.

abstract：:The combination of methotrexate and cyclosporine A (MTX-CSA) is the standard regimen for the prevention of graft vs. host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (allo-SCT) from HLA-identical siblings. Mycophenolate mofetil and CSA (MMF-CSA) combination has been successfully used for GV...

journal_title：Clinical transplantation

authors： Ostronoff F,Ostronoff M,Souto-Maior AP,Domingues M,Sucupira A,Manso DA,de Lima AK,Monteiro PG,Florêncio R,Calixto R

更新日期：2009-01-01 00:00:00

abstract：:Autoantibodies are frequently detected after liver transplantation (LT), but their role is unclear. This study was designed to address three points: autoantibody prevalence pre-LT and over time up to five yr after LT, identification of possible predictors of autoantibody formation, and correlation between autoantibodi...

journal_title：Clinical transplantation

authors： Foschi A,Zavaglia CA,Fanti D,Mazzarelli C,Perricone G,Vangeli M,Viganò R,Belli LS

更新日期：2015-02-01 00:00:00

abstract：:In the general population, obesity is associated with an increased risk of developing hypertension (HTN), type 2 diabetes mellitus (DM), and end-stage renal disease (ESRD). Therefore, most transplant centers have a body mass index (BMI) threshold for accepting living kidney donors. But there have been no studies of po...

journal_title：Clinical transplantation

authors： Issa N,Sánchez OA,Kukla A,Riad SM,Berglund DM,Ibrahim HN,Matas AJ

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:We performed a retrospective cohort study to determine the prognostic value of standard criteria donor/expanded criteria donor (SCD/ECD) designation, with regard to one-yr GFR and graft survival rate, in a region with short, cold ischemic time (CIT), and how this designation compares with the kidney donor ri...

journal_title：Clinical transplantation

authors： Han M,Jeong JC,Koo TY,Jeon HJ,Kwon HY,Kim YJ,Ryu HJ,Ahn C,Yang J

更新日期：2014-03-01 00:00:00

abstract：:The study explores the prevalence of unrecognized diabetes mellitus (DM), the incidence and risk factors new onset diabetes mellitus (NODM) and determines whether patient survival differs between patients with transient (NODM that resolves) compared with those with fixed NODM. This is a single center review of solitar...

journal_title：Clinical transplantation

authors： Kiberd M,Panek R,Kiberd BA

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:More data are needed regarding the incidence, risk factors, and outcomes for Clostridioides difficile infection (CDI) and colonization in patients undergoing an autologous hematopoietic stem cell transplantation (AHSCT). METHODS:We studied 472 consecutive patients admitted for a first AHSCT and conducted a ...

journal_title：Clinical transplantation

authors： Ford CD,Lopansri BK,Coombs J,Webb BJ,Nguyen A,Asch J,Hoda D

更新日期：2019-11-01 00:00:00

abstract：:We herein report the first case of immunosuppression-associated thrombotic microangiopathy (TMA) in which an extrarenal graft was primarily affected by the characteristic microvascular lesions. Although TMA is a well-known complication of cyclosporine (CSA) or tacrolimus therapy in renal and extrarenal (liver, heart, ...

journal_title：Clinical transplantation

authors： Humar A,Jessurun J,Sharp HL,Gruessner RW

更新日期：1998-12-01 00:00:00

abstract：:Survival despite prolonged non-adherence with immunosuppression is rare but has been reported in kidney, lung, and liver transplantation. Its occurrence in heart transplantation is quite rare. Our study was prompted by an index patient who survived despite prolonged medication non-adherence. Prospective consent and bl...

journal_title：Clinical transplantation

authors： Baran DA,Rao P,Deo D,Zucker MJ

更新日期：2020-05-01 00:00:00

abstract：:Renal transplantation was performed in a 24-yr-old woman with type AA systemic amyloidosis. Renal biopsy at 11 yr post-transplantation showed no amyloid recurrence, but the presence of mesangial proliferative glomerulonephritis and focal segmental glomerular sclerosis. Renal function was satisfactory with the exceptio...

journal_title：Clinical transplantation

authors： Nishikido M,Koga S,Kanetake H,Saito Y,Harada T,Taguchi T,Matsuya F,Shindo K

更新日期：1999-01-01 00:00:00

abstract：:During liver transplant (LT), the release of vasoactive substances into the systemic circulation is associated with severe hemodynamic instability that is injurious to the recipient and/or the post-ischemic graft. Crystalloid flush with backward unclamping (CB) and portal blood flush with forward unclamping (PF) are t...

journal_title：Clinical transplantation

authors： Fukazawa K,Nishida S,Hibi T,Pretto EA Jr

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The survival of patients returning to hemodialysis (HD) following kidney transplant failure is unfavorable. However, the factors responsible for this poor outcome are largely unknown; chronic inflammation due to failed allograft and malnutrition may contribute to morbidity and mortality. We aimed to compare ...

journal_title：Clinical transplantation

authors： Yelken BM,Gorgulu N,Caliskan Y,Yazici H,Turkmen A,Yildiz A,Sever MS

更新日期：2010-07-01 00:00:00

abstract：:Porto-pulmonary hypertension with moderate or severe pulmonary arterial hypertension (PAH) is viewed as a contraindication to liver transplantation (LT) because of associated poor outcomes; however, patients with biliary atresia (BA) are generally good candidates for LT. Ten patients with moderate/severe PAH underwent...

journal_title：Clinical transplantation

authors： Ogawa E,Hori T,Doi H,Segawa H,Uemoto S

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:In an effort to increase organ donation, the Department of Health and Human Services issued the Final Rule in 1998. The Health Care Financing Administration (HCFA) later required hospitals to notify organ procurement organizations (OPO) of all deaths and imminent deaths in order to remain eligible for Medica...

journal_title：Clinical transplantation

authors： Higashigawa KH,Carroll C,Wong LL,Wong LM

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Intraductal papillary mucinous neoplasms (IPMNs) of the pancreas are increasingly recognized in clinical practice. There are no published data suggesting a management approach for the potential organ transplant recipient with the incidental finding of this pre-malignant lesion. METHODS:The recipient was a 6...

journal_title：Clinical transplantation

authors： Fridell JA,Vianna R,Mangus RS,Kazimi M,Hollinger E,Joseph Tector A

更新日期：2008-09-01 00:00:00

abstract：:We sought to determine the incidence, risk factors, and consequences of acute rejection (AR) after conversion from a calcineurin inhibitor (CNI) to a proliferation signal inhibitor (PSI) in maintenance heart transplantation. Relevant clinical data were retrospectively obtained for 284 long-term heart transplant recipi...

journal_title：Clinical transplantation

authors： González-Vílchez F,Vázquez de Prada JA,Paniagua MJ,Almenar L,Mirabet S,Gómez-Bueno M,Díaz-Molina B,Arizón JM,Delgado J,Pérez-Villa F,Crespo-Leiro MG,Martínez-Dolz L,Roig E,Segovia J,Lambert JL,Lopez-Granados A,Escribano P

更新日期：2013-11-01 00:00:00

abstract：:Renal transplantation offers patients with end-stage renal disease the best opportunity for rehabilitation and long-term survival. However, there is a critical shortage of transplantable kidneys worldwide. This plays well into the hands of transplanters and entrepreneurs involved in commercial renal transplantation, p...

journal_title：Clinical transplantation

authors： Qunibi W,Abulrub D,Shaheen F,el-Din AB,Alfurayh O,Almeshari K

更新日期：1995-08-01 00:00:00

abstract：:The organ shortage is one of the major challenges in the field of organ transplantation, yet the percentage of kidneys procured and discarded prior to transplantation has continued to rise to twenty percent. The causes of organ discard are complex, yet an urgent need exists for collaborative efforts to maximize the ut...

journal_title：Clinical transplantation

authors： Cooper M,Formica R,Friedewald J,Hirose R,O'Connor K,Mohan S,Schold J,Axelrod D,Pastan S

更新日期：2019-01-01 00:00:00

abstract：:Clinical outcomes are generally worse for black vs nonblack renal allograft recipients. In BENEFIT and BENEFIT-EXT, recipients were randomized to belatacept more intense-based, belatacept less intense-based, or cyclosporine-based immunosuppression. At year 7, belatacept was associated with superior graft survival vs c...

journal_title：Clinical transplantation

authors： Florman S,Vincenti F,Durrbach A,Abouljoud M,Bresnahan B,Garcia VD,Mulloy L,Rice K,Rostaing L,Zayas C,Calderon K,Meier-Kriesche U,Polinsky M,Yang L,Medina Pestana J,Larsen CP

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:To assess the diagnostic value of magnetic resonance cholangiography (MRC) when evaluating biliary complications in a large series of liver transplants. METHODS:One hundred and twenty-nine patients prospectively underwent magnetic resonance (MR) imaging and MR cholangiography at 1.5-T device after orthotopi...

journal_title：Clinical transplantation

authors： Boraschi P,Donati F,Gigoni R,Volpi A,Salemi S,Filipponi F,Falaschi F

更新日期：2010-07-01 00:00:00

abstract：AIM:To explore the trends in the risk for rejection following heart transplantation (HT) over the past 25 years, and their relation to changes in medical management. METHODS:The study population comprised 216 HT patients. Rejection periods were defined as follows: 0-3 months (early), 3-12 months (intermediate), and 12...

journal_title：Clinical transplantation

authors： Katz M,Freimark D,Raichlin E,Har-Zahav Y,Arad M,Kassif Y,Peled A,Asher E,Elian D,Kogan A,Shlomo N,Ofek E,Lavee J,Goldenberg I,Peled Y

更新日期：2017-10-01 00:00:00

abstract：:Kidney transplant obstruction (KTO) following renal transplantation remains an important reversible cause of allograft dysfunction, requiring prompt diagnosis to prevent long-term graft damage. Although ultrasound can accurately diagnose renal transplant hydronephrosis, it cannot be used to assess its functional signi...

journal_title：Clinical transplantation

authors： Nankivell BJ,Cohn DA,Spicer ST,Evans SG,Chapman JR,Gruenewald SM

更新日期：2001-02-01 00:00:00

abstract：:Calcineurin inhibitors (CNI) are the mainstay of immunosuppression after liver transplantation (LT), but CNIs are associated with significant nephrotoxicity. Recently, mTOR inhibitors such as sirolimus and everolimus (EVR) have been used with or without CNIs in LT recipients for their renal-sparing effect. We conducte...

journal_title：Clinical transplantation

authors： Lin M,Mittal S,Sahebjam F,Rana A,Sood GK

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:The benefits of pancreas transplantation are often difficult to measure. Here, we sought to determine the difference in quality of life for diabetic patients with and without a functional pancreas transplant alone (PTA). METHODS:Pancreas transplant alone cases from 1993 to 2015 were considered. An IRB-appro...

journal_title：Clinical transplantation

authors： Scalea JR,Pettinato L,Fiscella B,Bartosic A,Piedmonte A,Paran J,Todi N,Siskind EJ,Bartlett ST

更新日期：2018-02-01 00:00:00

abstract：:We investigated tolerability and efficacy of ezetimibe treatment (10 mg/d) in 25 heart allograft recipients already on stable statin therapy. Total cholesterol (TC), low-density cholesterol (LDL-C), high-density cholesterol (HDL-C), triglycerides (TG), immunosuppressant drug levels, laboratory and clinical parameters ...

journal_title：Clinical transplantation

authors： Konstandin MH,Blessing E,Doesch A,Ammon K,Koch A,Wabnitz GH,Gleissner CA,Remppis A,Katus HA,Dengler TJ

更新日期：2008-09-01 00:00:00

abstract：:The current pandemic SARS-CoV-2 has required an unusual allocation of resources that can negatively impact chronically ill patients and high-complexity procedures. Across the European Reference Network on Pediatric Transplantation (ERN TransplantChild), we conducted a survey to investigate the impact of the COVID-19 o...

journal_title：Clinical transplantation

authors： Doná D,Torres Canizales J,Benetti E,Cananzi M,De Corti F,Calore E,Hierro L,Ramos Boluda E,Melgosa Hijosa M,Garcia Guereta L,Pérez Martínez A,Barrios M,Costa Reis P,Teixeira A,Lopes MF,Kaliciński P,Branchereau S,Boyer O

更新日期：2020-10-01 00:00:00

abstract：:It is unclear whether a concomitant kidney transplant grants survival benefit to liver transplant (LT) candidates with renal dysfunction (RD). We retrospectively studied LT candidates without RD (n = 714) and LT candidates with RD who underwent either liver transplant alone (RD-LTA; n = 103) or simultaneous liver-kidn...

journal_title：Clinical transplantation

authors： Brennan TV,Lunsford KE,Vagefi PA,Bostrom A,Ma M,Feng S

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:The average age of patients undergoing liver transplantation (LT) is consistently increasing. The aim of this case-control study is to evaluate survival and outcome of patients ≥65 yr compared to younger patients undergoing LT. MATERIALS AND METHODS:From 10/00 to 4/08 we performed 330 primary LT, 31 (9.4%...

journal_title：Clinical transplantation

authors： Montalti R,Rompianesi G,Di Benedetto F,Ballarin R,Gerring RC,Busani S,De Pietri L,De Ruvo N,Iemmolo RM,Guerrini GP,Smerieri N,Gerunda GE

更新日期：2010-09-01 00:00:00

abstract：:Steroid-resistant acute rejection (SR-AR) and ductopenic rejection (DR) after liver transplantation are infrequent, but difficult to manage. We performed a retrospective review of patients with SR-AR or DR treated with sirolimus-based therapy. Since 2002, we have treated five patients with SR-AR and eight patients wit...

journal_title：Clinical transplantation

authors： Lladó L,Fabregat J,Castellote J,Ramos E,Torras J,Serrano T,Figueras J,Rafecas A

更新日期：2009-01-01 00:00:00

abstract：:Use of C(2) monitoring for cyclosporine A (CsA) microemulsion results in improved clinical outcomes vs. trough (C(0)) monitoring. Logistical issues include accurate timing of the C(2) sample; requirement for sample dilution with most standard assay techniques; and inconvenience for patients. Recently, it has been show...

journal_title：Clinical transplantation

authors： Yonan N,Martyszczuk R,Machaal A,Baynes A,Keevil BG

更新日期：2006-03-01 00:00:00

abstract：:Immunosuppression leaves transplanted patients at particular risk for severe acute respiratory syndrome 2 (SARS-CoV-2) infection. The specific features of coronavirus disease 2019 (COVID-19) in immunosuppressed patients are largely unknown and therapeutic experience is lacking. Seven transplanted patients (two liver, ...

journal_title：Clinical transplantation

authors： Bösch F,Börner N,Kemmner S,Lampert C,Jacob S,Koliogiannis D,Stangl M,Michel S,Kneidinger N,Schneider C,Fischereder M,Irlbeck M,Denk G,Werner J,Angele MK,Guba MO

更新日期：2020-10-01 00:00:00