Secondary cytoreductive surgery in the management of platinum-sensitive recurrent epithelial ovarian cancer.

Abstract:

BACKGROUND AND OBJECTIVES:To assess the surgical and survival outcomes after secondary cytoreductive surgery (SCRS) in patients with platinum-sensitive recurrent epithelial ovarian cancer (EOC) and to identify patients who would most benefit from SCRS. METHODS:Inclusion criteria consisted of (1) recurrent EOC; (2) disease-free interval (DFI) >or=6 months after primary therapy; and (3) SCRS with therapeutic intent followed by adjuvant chemotherapy. RESULTS:Sixty-seven patients met the inclusion criteria in the interval 1992-2008. Median DFI was 20 months (range: 6-109 months). Median time in surgery was 240 min (range: 60-680 min), and median estimated blood loss was 100 ml (range: 50-3,000 ml). There was no significant perioperative complication requiring reoperation. Complete resection of all visible tumor tissue was achieved in 37 patients (55.2%), with residual tumors (RT) 24 months and RT 24 months and patients who achieved optimal cytoreduction.

journal_name

J Surg Oncol

authors

Park JY,Eom JM,Kim DY,Kim JH,Kim YM,Kim YT,Nam JH

doi

10.1002/jso.21470

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

418-24

issue

5

eissn

0022-4790

issn

1096-9098

journal_volume

101

pub_type

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