Discrepancies between two automated immunoassay systems in determining hepatitis B virus markers in serum samples with concomitant presence of antigens and antibodies.

Abstract:

:This study compared the assay results of HBV markers obtained with two automated immunoassay systems in serum samples with concomitant HBV antigens and antibodies. Eighty-nine samples of concomitant HBsAg and anti-HBs and 74 samples of concomitant HBeAg and anti-HBe were analyzed by the Abbott Architect i2000 and the Roche Elecsys 2010 immunoassay systems. The overall concordance rates of the Architect and Elecsys results were 78.6% for samples with concomitant HBsAg and anti-HBs and 77% for samples with concomitant HBeAg and anti-HBe. The data show that substantial differences exist between the results obtained by these two systems, especially in determining anti-HBs and HBeAg at low concentrations.

journal_name

Ann Clin Lab Sci

authors

Cheng L,Guan Q,Zhang J,Sun Z

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

49-52

issue

1

eissn

0091-7370

issn

1550-8080

pii

40/1/49

journal_volume

40

pub_type

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