Neuropeptide modulation of murine erythropoiesis.

Abstract:

:Neuropeptide modulation of hematopoietic stem cell differentiation was studied in an in vitro murine system. Endorphins were able to influence the erythropoietin-dependent differentiation of bone marrow cells into erythroid colony forming units in a dose dependent manner. The effects on progenitor cell maturation were influenced by the conditions and time of exposure to the endorphins. The modulation of erythropoiesis by the endorphins suggests that these peptides may function as modifiers of the maturation of bone marrow cells.

journal_name

Ann Clin Lab Sci

authors

Skelly RR,Fata J,Sharkis SJ,Sensenbrenner L,Ansari AA

subject

Has Abstract

pub_date

1987-09-01 00:00:00

pages

324-30

issue

5

eissn

0091-7370

issn

1550-8080

journal_volume

17

pub_type

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