Abstract:
:Aloin is a physiologically active anthraquinone present in aloe. There are two isomers of aloin, aloin A and aloin B, occurring as a mixture of diastereomers. The objective of this study was to determine the bioavailability and tissue distribution of aloin. Rats were gavaged with 11.8g/kg aloin, and the levels of aloin and its conjugates were measured in plasma, tissues, and urine. Plasma aloin level showed a peak at 1hr after the administration and the concentration was 59.07+/-10.5 ng/ml. The 24 h cumulated urinary aloin was 0.03% of the initial dose. These results suggest that aloin is absorbed and reaches a peak plasma level within 1-1.5 h after the administration and a significant portion is possibly metabolized or is excreted in feces. These results can apply to the determination of the adequate intake level of aloe and aloe products to achieve the desired biological effect, and to interprete in vitro study results.
journal_name
Nutr Res Practjournal_title
Nutrition research and practiceauthors
Park MY,Kwon HJ,Sung MKdoi
10.4162/nrp.2008.2.1.17subject
Has Abstractpub_date
2008-04-01 00:00:00pages
17-21issue
1eissn
1976-1457issn
2005-6168journal_volume
2pub_type
杂志文章abstract::The purpose of this study was to compare the beverage consumption by gender and season in elementary school children and to investigate the role of beverage consumption patterns on their daily nutrient intakes and BMIs. Beverage consumption and dietary energy intake in 160 elementary school students in the Gyeongnam a...
journal_title:Nutrition research and practice
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journal_title:Nutrition research and practice
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journal_title:Nutrition research and practice
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journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2013.7.4.249
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journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2008.2.2.80
更新日期:2008-07-01 00:00:00
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journal_title:Nutrition research and practice
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更新日期:2016-06-01 00:00:00
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pub_type: 杂志文章,撤回出版物
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更新日期:2019-02-01 00:00:00
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更新日期:2020-10-01 00:00:00
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更新日期:2015-02-01 00:00:00
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journal_title:Nutrition research and practice
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doi:10.4162/nrp.2012.6.2.120
更新日期:2012-04-01 00:00:00
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journal_title:Nutrition research and practice
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journal_title:Nutrition research and practice
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更新日期:2007-04-01 00:00:00
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journal_title:Nutrition research and practice
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journal_title:Nutrition research and practice
pub_type: 杂志文章
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更新日期:2008-01-01 00:00:00
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journal_title:Nutrition research and practice
pub_type: 杂志文章
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更新日期:2009-04-01 00:00:00
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journal_title:Nutrition research and practice
pub_type: 杂志文章
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更新日期:2019-04-01 00:00:00
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journal_title:Nutrition research and practice
pub_type: 已发布勘误
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