Abstract:
BACKGROUND/OBJECTIVE:The aim of this study was to examine the effect of high dietary methionine (Met) consumption on plasma and hepatic oxidative stress and dyslipidemia in chronic ethanol fed rats. MATERIALS/METHODS:Male Wistar rats were fed control or ethanol-containing liquid diets supplemented without (E group) or with DL-Met at 0.6% (EM1 group) or 0.8% (EM2 group) for five weeks. Plasma aminothiols, lipids, malondialdehyde (MDA), alanine aminotransferase (ALT), and aspartate aminotransferase were measured. Hepatic folate, S-adenosylmethionine (SAM), and S-adenosylhomocysteine (SAH) were measured. RESULTS:DL-Met supplementation was found to increase plasma levels of homocysteine (Hcy), triglyceride (TG), total cholesterol (TC), and MDA compared to rats fed ethanol alone and decrease plasma ALT. However, DL-Met supplementation did not significantly change plasma levels of HDL-cholesterol, cysteine, cysteinylglycine, and glutathione. In addition, DL-Met supplementation increased hepatic levels of folate, SAM, SAH, and SAM:SAH ratio. Our data showed that DL-Met supplementation can increase plasma oxidative stress and atherogenic effects by elevating plasma Hcy, TG, and TC in ethanol-fed rats. CONCLUSION:The present results demonstrate that Met supplementation increases plasma oxidative stress and atherogenic effects by inducing dyslipidemia and hyperhomocysteinemia in ethanol-fed rats.
journal_name
Nutr Res Practjournal_title
Nutrition research and practiceauthors
Kim SY,Kim H,Min Hdoi
10.4162/nrp.2015.9.2.144subject
Has Abstractpub_date
2015-04-01 00:00:00pages
144-9issue
2eissn
1976-1457issn
2005-6168journal_volume
9pub_type
杂志文章abstract:BACKGROUND:A higher frequency of family meals is associated with good dietary habits in young people. This study focused on the relationships of family meal frequency with food neophobia and personality traits in adolescents. SUBJECTS/METHOD:For this purpose, we administered a survey to 495 middle school students in S...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2014.8.4.476
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Groundwater is believed to possess many beneficial effects due to its natural source of various minerals. In this study, we examined the effects of natural Jeju groundwater S1 (Samdasoo™), S2 and S3 pumped up from different locations of Jeju Island, Korea, along with local tap water, on body weight gain, ser...
journal_title:Nutrition research and practice
pub_type: 杂志文章
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journal_title:Nutrition research and practice
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doi:10.4162/nrp.2016.10.6.623
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abstract::Zinc is an essential trace element required for bone formation, however not much has been clarified yet for its role in osteoblast. We hypothesized that zinc would increase osteogenetic function in osteoblasts. To test this, we investigated whether zinc treatment enhances bone formation by stimulating osteoblast proli...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2010.4.5.356
更新日期:2010-10-01 00:00:00
abstract::In this study, the soy food intake behaviors including perception and intake frequency of soybean foods by sociodemographic variables were analyzed in housewives. The perception of housewives for soy foods showed that soybean paste, soybean curd, and Dambuk were high in the descending order for nutritional quality and...
journal_title:Nutrition research and practice
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doi:10.4162/nrp.2008.2.4.275
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abstract::In this study, the protective effects of EGCG on L-3,4-dihydroxyphenylalanine (L-DOPA)-induced oxidative cell death in catecholaminergic PC12 cells, the in vitro model of Parkinson's disease, were investigated. Treatment with L-DOPA at concentrations higher than 150 µM caused cytotoxicity in PC12 cells, as determined ...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2013.7.4.249
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abstract::The rapid rise in the incidence of obesity has emerged as one of the most pressing global public health issues in recent years. The underlying etiological causes of obesity, whether behavioral, environmental, genetic, or a combination of several of them, have not been completely elucidated. The obesity epidemic has be...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2011.5.3.253
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abstract:BACKGROUND/OBJECTIVES:This cross-sectional study assessed household food security status and determined its association with diet quality and weight status among indigenous women from the Mah Meri tribe in Peninsular Malaysia. SUBJECTS/METHODS:The Radimer/Cornell Hunger and Food Insecurity Instrument and the Malaysian...
journal_title:Nutrition research and practice
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doi:10.4162/nrp.2018.12.2.135
更新日期:2018-04-01 00:00:00
abstract:BACKGROUD/OBJECTIVES:Hepatic steatosis is the most common liver disorder, particularly in postmenopausal women. This study investigated the protective effects of standardized rice bran extract (RBS) on ovariectomized (OVX)-induced hepatic steatosis in rats. MATERIALS/METHODS:HepG2 cells were incubated with 200 µM olei...
journal_title:Nutrition research and practice
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journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2019.13.3.222
更新日期:2019-06-01 00:00:00
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journal_title:Nutrition research and practice
pub_type: 已发布勘误
doi:10.4162/nrp.2015.9.2.213
更新日期:2015-04-01 00:00:00
abstract::Dietary sodium intake is considered one of the major causal factors for hypertension. Thus, to control the increase of blood pressure and reduce the risk of hypertension-related clinical complications, a reduction in sodium intake is recommended. The present study aimed at determining the association of dietary sodium...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2013.7.3.192
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Serum ferritin levels are significantly increased after menopause and greatly affect women's health. The aim of this study was to investigate the dietary and non-dietary factors associated with high ferritin levels in postmenopausal women. SUBJECTS/METHODS:Among adult women in 2010-2012, qualifie...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2016.10.1.81
更新日期:2016-02-01 00:00:00
abstract::Obesity may be the consequence of various environmental or genetic factors, which may be highly correlated with each other. We aimed to examine whether grandmaternal and maternal obesity and environmental risk factors are related to obesity in daughters. Daughters (n = 182) recruited from female students, their mother...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2013.7.5.400
更新日期:2013-10-01 00:00:00
abstract::The purpose of this study was to examine consumers' behaviors toward ready-to-eat foods and to develop ready-to-eat food market segmentation in Korea. The food-related lifestyle and purchase behaviors of ready-to-eat foods were evaluated using 410 ready-to-eat food consumers in the Republic of Korea. Four factors were...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2010.4.4.332
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Several nutritional screening tools were recently developed to screen the risk of malnutrition in hospitalized children, but have not been validated in Asia. We compared four nutritional screening tools for pediatric patients in evaluating nutritional risks in newly hospitalized children. SUBJECT...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2019.13.5.410
更新日期:2019-10-01 00:00:00
abstract::Aloin is a physiologically active anthraquinone present in aloe. There are two isomers of aloin, aloin A and aloin B, occurring as a mixture of diastereomers. The objective of this study was to determine the bioavailability and tissue distribution of aloin. Rats were gavaged with 11.8g/kg aloin, and the levels of aloi...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2008.2.1.17
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:This study aimed to investigate the association of dietary patterns with overweight risk and all-cause mortality in pediatric cancer patients. SUBJECTS/METHODS:Prospective cohort study was undertaken; 83 cancer patients admitted to the pediatric cancer ward at a university hospital in Seoul were ...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2017.11.6.492
更新日期:2017-12-01 00:00:00
abstract::We conducted two studies to determine the effect of gender, gonadectomy (GDX) on growth and plasma cholesterol levels in pigs. In experiment 1, five sham-operated and five GDX female Landrace pigs (26 kg) were allowed to have free access to water and feed up to market weight (approximately 100 kg). Body weight and fee...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2009.3.1.38
更新日期:2009-04-01 00:00:00
abstract::Forty guinea pigs were divided into four groups and fed 0.04% cholesterol based control diet, plus 0.05% simvastatin, and statin plus 0.1% CoQ10 or 10% Ardisia Japonica Blume (AJB) leave powder for 4 weeks. Plasma total cholesterol levels decreased significantly in all groups fed the statin-containing diet compared wi...
journal_title:Nutrition research and practice
pub_type: 杂志文章
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journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2016.10.4.424
更新日期:2016-08-01 00:00:00
abstract::The most critical point in the assessment of adherence to dietary guidelines is the development of a practical definition for adherence, such as a dietary pattern score. The purpose of this study was to develop the Korean Diet Score (KDS) based on the Korean Food Balance Wheel and to examine the association of KDS wit...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2013.7.1.49
更新日期:2013-02-01 00:00:00
abstract::This study was conducted to investigate the effect of dietary grape skin on lipid peroxidation and antioxidant defense system in rats fed high fat diet. The Sprague-Dawley rats were fed either control (5% fat) diet or high fat (25% fat) diet which was based on AIN-93 diet for 2 weeks, and then they were grouped as con...
journal_title:Nutrition research and practice
pub_type: 杂志文章
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更新日期:2009-01-01 00:00:00
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journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2018.12.3.243
更新日期:2018-06-01 00:00:00
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journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2008.2.2.80
更新日期:2008-07-01 00:00:00
abstract::The purpose of this study was to estimate the daily manganese (Mn) intake of Korean children. This study was done using a three-day dietary intake survey of 257 Korean children (boys 123; girls 134). The Mn intake values were calculated based on a database that provides the Mn content of the frequently consumed Korean...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2011.5.6.548
更新日期:2011-12-01 00:00:00
abstract::The abnormal content of blood lipids often results in metabolic diseases, such as hyperlipidemia and obesity. Many agents, including natural sources from traditional food, have been developed to regulate the blood lipid contents. In this study, we examined the anti-hyperlipidemic activity of Rhynchosia nulubilis seeds...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2013.7.6.453
更新日期:2013-12-01 00:00:00
abstract::The aim of this study was to investigate the influencing factors that characterize low density lipoprotein (LDL) phenotype and the levels of LDL particle size in healthy Korean women. In 57 healthy Korean women (mean age, 57.4 ± 13.1 yrs), anthropometric and biochemical parameters such as lipid profiles and LDL partic...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2012.6.2.120
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Oligonol, mainly found in lychee fruit, is an antioxidant polyphenolic compound which has been shown to have anti-inflammatory and anti-cancer properties. The detailed mechanisms by which oligonol may act as an anti-aging molecule have not been determined. MATERIALS/METHODS:In this study, we eval...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2016.10.1.3
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Iron deficiency in early life is associated with developmental problems, which may persist until later in life. The question of whether iron repletion after developmental iron deficiency could restore iron homeostasis is not well characterized. In the present study, we investigated the changes of ...
journal_title:Nutrition research and practice
pub_type: 杂志文章
doi:10.4162/nrp.2015.9.6.613
更新日期:2015-12-01 00:00:00