Arterial ketone body ratio as a possible indicator for liver transplantation in fulminant hepatic failure.

abstract：BACKGROUND:Cyclosporine (CsA) therapy must often be continued during pregnancy to maintain maternal health in such conditions as organ transplantation and autoimmune disease. This meta-analysis was performed to determine whether CsA exposure during pregnancy is associated with an increased risk of congenital malformati...

journal_title：Transplantation

authors： Bar Oz B,Hackman R,Einarson T,Koren G

更新日期：2001-04-27 00:00:00

abstract：BACKGROUND:Human leukocyte antigen (HLA) antibodies were normally not found in subjects who have not been immunized by pregnancies, transfusions, or transplants. But with new methodology, we now see that HLA antibodies are often found in nonalloimmunized males. METHODS:The sera of 424 healthy male donors were tested w...

journal_title：Transplantation

authors： Morales-Buenrostro LE,Terasaki PI,Marino-Vázquez LA,Lee JH,El-Awar N,Alberú J

更新日期：2008-10-27 00:00:00

abstract：:Pancreatic transplantation is intended to normalize carbohydrate metabolism in insulin-dependent diabetics by restoring endogenous insulin release, and it is usually performed together with kidney transplantation in patients with end-stage renal failure. A major problem in these patients is the daily control of the gr...

journal_title：Transplantation

authors： Secchi A,Pontiroli AE,Traeger J,Dubernard JM,Touraine JL,Ruitton A,Blanc N,Pozza G

更新日期：1983-04-01 00:00:00

abstract：:Rat, hamster, and rabbit islets were transplanted into diabetic C57BL/B6 mice. The effect on islet xenograft survival of low-temperature culture of the donor islets, alpha L3T4 treatment of the recipients for seven days, and transplantation of the grafts either in the renal capsule or in the liver via the portal vein ...

journal_title：Transplantation

authors： Lacy PE,Ricordi C,Finke EH

更新日期：1989-05-01 00:00:00

abstract：:Despite growing evidence that reactive oxygen species are responsible for deleterious effects of ischemia-reperfusion (I/R) injury of the liver, there exists, until now, no reliable antioxidant therapeutics applicable in the clinical setting. We investigated the effects of free radical scavenger, 3-methyl-1-phenyl-2-p...

journal_title：Transplantation

authors： Ninomiya M,Shimada M,Harada N,Shiotani S,Hiroshige S,Soejima Y,Suehiro T,Sugimachi K

更新日期：2002-11-27 00:00:00

abstract：BACKGROUND:Preexisting IgG antibodies to donor human leukocyte antigens (HLA) are a risk factor for rapid allograft rejection. However, non-HLA antibodies, of the IgM class, also called autoreactive antibodies, are not believed to affect graft survival. The aim of this study was to determine the incidence and clinical ...

journal_title：Transplantation

authors： Smith JD,Hamour IM,Burke MM,Mahesh B,Stanford RE,Haj-Yahia S,Robinson DR,Kaul P,Yacoub MH,Banner NR,Rose ML

更新日期：2009-03-27 00:00:00

abstract：:Retrospective mixed leukocyte culture studies were performed in eight patients who had either rejected their marrow grafts or experienced graft-versus-host disease and in seven patients with successful marrow engraftment. In tests of pre-and post-transplant lymphocytes we found no evidence that rejection or graft-vers...

journal_title：Transplantation

authors： Opelz G,Gale RP

更新日期：1976-11-01 00:00:00

abstract：:Since the earliest days of transplantation, immunobiologists have sought means to prevent recognition and rejection of foreign tissue. The goal of these strategies is the retention of recipient immune function while selectively avoiding graft injury. Although considerable theoretical and technical problems remain, an ...

journal_title：Transplantation

authors： Lynch RJ,Platt JL

更新日期：2009-12-15 00:00:00

abstract：:ICAM-1 is an inducible glycoprotein important in the adhesion, activation, and transmigration of circulating leukocytes across the vascular endothelial monolayer, and it likely plays a key role in the allogeneic response. To determine the reproducibility and significance of variations in resting levels of cell surface...

journal_title：Transplantation

authors： Everett JP,Shipley GD,Mauck KA,Wagner CR,Morris TE,Hosenpud JD

更新日期：1994-10-27 00:00:00

abstract：:Histoincompatibility was analyzed to describe as precisely as possible the sequence of gross morphological events taking place during allograft rejection among closely related conspecifics from a natural population of the bisexual lizard Cnemidophorus tigris. Two types of rejection were noted, depending on whether the...

journal_title：Transplantation

authors： Cuellar O,Smart C

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:FK506-binding proteins (FKBP) are immunophilins that interact with the immunosuppressive drugs FK506 and rapamycin. Several FKBP family members such as FKBP12, FKBP12.6, and FKBP51 are expressed in T cells. It has been speculated that these FKBPs are possibly redundant in the immunosuppressant-induced T-cell...

journal_title：Transplantation

authors： Xu X,Su B,Barndt RJ,Chen H,Xin H,Yan G,Chen L,Cheng D,Heitman J,Zhuang Y,Fleischer S,Shou W

更新日期：2002-06-15 00:00:00

abstract：BACKGROUND:Graft-versus-host disease (GVHD) is a major complication after bone marrow transplantation, which may be refractory to immunosuppressive drugs. As preliminary case reports suggested that extracorporeal photochemotherapy (ECP) using a Therakos device might be beneficial, we conducted a pilot study to assess t...

journal_title：Transplantation

authors： Besnier DP,Chabannes D,Mahé B,Mussini JM,Baranger TA,Muller JY,Milpied N,Esnault VL

更新日期：1997-07-15 00:00:00

abstract：BACKGROUND:Infections and acute graft-versus-host disease (GvHD) represent major complications of allogeneic stem-cell transplantation (SCT). Dendritic cells (DCs) display an extraordinary capacity to induce innate and adaptive immune responses. Therefore, they play a crucial role in the elimination of pathogens and in...

journal_title：Transplantation

authors： Mager K,Wehner R,Bahr F,Oelschlägel U,Platzbecker U,Wermke M,Shayegi N,Middeke JM,Radke J,Röllig C,Schetelig J,Thiede C,Ehninger G,Schmitz M,Bornhäuser M,Tuve S

更新日期：2012-06-27 00:00:00

abstract：BACKGROUND:The risk associated with transplantation of renal allografts from hepatitis B virus core antibody-positive (HBcAb(+)), hepatitis B virus surface antigen-negative (HBsAg(-)) donors is not well defined. METHODS:Over 4 years, we performed 45 kidney transplants from IgG HBcAb(+), IgM HBcAb(-), HBsAg(-) donors i...

journal_title：Transplantation

authors： Madayag RM,Johnson LB,Bartlett ST,Schweitzer EJ,Constantine NT,McCarter RJ Jr,Kuo PC,Keay S,Oldach DW

更新日期：1997-12-27 00:00:00

abstract：:The effects of dietary (10% calories) safflower (SAF), evening primrose (EPO), and fish oil (F) as sources of linoleic acid (control), gamma-linolenic acid, and long-chain n-3 fatty acids, respectively, on cardiovascular and renal responses to chronic (5 weeks) cyclosporine administration were studied in male borderli...

journal_title：Transplantation

authors： Mills DE,Ward RP,McCutcheon D,Dixon H,Ly H,Scholey J

更新日期：1992-03-01 00:00:00

abstract：:A retrospective masked study of 120 consecutive renal transplant biopsies was performed to evaluate the potential associations of cyclosporine (CsA) therapy and other factors on the degree and progression of interstitial fibrosis (IF). Allograft biopsies were obtained from patients receiving CsA (CsA+; n = 59) and not...

journal_title：Transplantation

authors： Ruiz P,Kolbeck PC,Scroggs MW,Sanfilippo F

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:There is an increasing appreciation of the deleterious effects of antibody and B cells on acute and chronic transplant outcomes. Many effector functions of antibody are mediated by a family of receptors (FcγRs) that are expressed on most immune cells, including neutrophils, natural killer cells, and B cells....

journal_title：Transplantation

authors： Clatworthy MR,Matthews RJ,Doehler B,Willcocks LC,Opelz G,Smith KGC

更新日期：2014-08-15 00:00:00

abstract：BACKGROUND:The impact of community-acquired respiratory virus (CARV) infections on bronchiolitis obliterans syndrome (BOS) and outcome after lung transplantation (LTx) and diagnostic techniques were prospectively evaluated. METHODS:A single-center prospective cohort study was performed in LTx-outpatients between Octob...

journal_title：Transplantation

authors： Gottlieb J,Schulz TF,Welte T,Fuehner T,Dierich M,Simon AR,Engelmann I

更新日期：2009-05-27 00:00:00

abstract：:Hepatocyte allotransplantation has been performed successfully in several small animal models for the amelioration of inborn metabolic errors. Before a human clinical trial of hepatocyte allotransplantation can be attempted, preliminary experience in a large animal model is needed. We transplanted isolated mongrel hep...

journal_title：Transplantation

authors： Benedetti E,Kirby JP,Asolati M,Blanchard J,Ward MG,Williams R,Hewett TA,Fontaine M,Pollak R

更新日期：1997-05-15 00:00:00

abstract：:Leflunomide is a compound recently shown to reduce T and B cell-mediated responses in a number of experimental rat, mouse, and human systems. To explore its potential as an immunosuppressant, we studied leflunomide in 128 Brown-Norway/Lewis cardiac transplants and in 48 unoperated Lewis rats. At doses ranging from 0.6...

journal_title：Transplantation

authors： Williams JW,Xiao F,Foster P,Clardy C,McChesney L,Sankary H,Chong AS

更新日期：1994-04-27 00:00:00

abstract：:Rapamycin prolongs allograft survival and induces donor-specific tolerance in some small animal transplant models. Large animal studies, however, are limited. We studied rapamycin in a porcine renal allograft model. Donor-recipient combinations were chosen based on high response in pretransplant MLCs. Allografts were ...

journal_title：Transplantation

authors： Almond PS,Moss A,Nakhleh RE,Melin M,Chen S,Salazar A,Shirabe K,Matas AJ

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:We studied whether T-cell clones, which appear in the periphery as a result of the failure of thymic negative selection during graft-versus-host disease (GVHD), have any in vivo anti-host reactivity and can cause GVHD in an adoptive transfer model. METHODS:We performed our studies in a murine model (B10.BR ...

journal_title：Transplantation

authors： van den Brink MR,Moore E,Ferrara JL,Burakoff SJ

更新日期：2000-02-15 00:00:00

abstract：BACKGROUND:More than 30% of potential kidney transplant recipients have pre-existing anti-human leukocyte antigen antibodies. This subgroup has significantly lower transplant rates and increased mortality. Desensitization has become an important tool to overcome this immunological barrier. However, limited data is avai...

journal_title：Transplantation

authors： Riella LV,Safa K,Yagan J,Lee B,Azzi J,Najafian N,Abdi R,Milford E,Mah H,Gabardi S,Malek S,Tullius SG,Magee C,Chandraker A

更新日期：2014-06-27 00:00:00

abstract：:The majority of skin tumors induced in mice by ultraviolet (UV) light are rejected when implanted into normal syngeneic recipients. Subcarcinogenic levels of UV light exposure render the normally resistant mice susceptible to tumor challenge. The immunoregulatory effect of UV light appears to be additive, since the gr...

journal_title：Transplantation

authors： Daynes RA,Spellman CW,Woodward JG,Stewart DA

更新日期：1977-04-01 00:00:00

abstract：BACKGROUND:The use of liver allografts from an older donor (OD) (age>50 years) is a widespread strategy to manage the disparity between supply and demand of organs for liver transplantation. This study determines the effect of OD allografts on fibrosis progression and graft survival after liver transplantation in patie...

journal_title：Transplantation

authors： Machicao VI,Bonatti H,Krishna M,Aqel BA,Lukens FJ,Nguyen JH,Rosser BG,Satyanarayana R,Grewal HP,Hewitt WR,Harnois DM,Crook JE,Steers JL,Dickson RC

更新日期：2004-01-15 00:00:00

abstract：:Serum IgA levels were monitored at 3, 6, 12, and 24 months after BMT in 131 allogeneic and 3 syngeneic bone marrow transplant recipients. In general, IgA levels were low during the first 6 months and did not return to normal levels until 1-2 years after transplantation. Children (less than 15 years) had lower IgA leve...

journal_title：Transplantation

authors： Abedi MR,Hammarström L,Ringdén O,Smith CI

更新日期：1990-09-01 00:00:00

abstract：:To determine the degree of graft versus host disease (GVHD) prophylaxis that might be necessary if cord blood (CB) transplantation is more widely applied, we compared human cord blood mononuclear cell (CBMC) and adult peripheral blood mononuclear cell (PBMC) proliferative responses and stimulatory capabilities; to exa...

journal_title：Transplantation

authors： Greenfeld JI,Noizat-Pirenne F,Hardy MA,Oluwole SF,Hesdorffer CA,Preti RA,De Groote D,Franchimont P

更新日期：1994-08-27 00:00:00

abstract：BACKGROUND:To investigate the transparency, biocompatibility, and safety of human-derived acellular dermal matrix for application in corneal stromal transplantation. METHODS:Twenty-four patients (24 eyes) with pellucid marginal corneal degeneration were enrolled, and intrastromal keratoplasty was performed with human-...

journal_title：Transplantation

authors： Jiang X,Wang Y,Qiu W,Huang C,Liu Z,Ding T,Shi D,Li X

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Human lung transplantation carries a poor prognosis because of chronic rejection in the form of obliterative bronchiolitis syndrome (OBS). Using the mouse model of heterotopic tracheal transplantation, we examined the role of costimulation in the allograft rejection that characterizes obstructive airway dise...

journal_title：Transplantation

authors： Rumbley CA,Silver SJ,Phillips SM

更新日期：2001-11-27 00:00:00

abstract：:Using antisera to human beta2-microglobulin and an immunofluorescent technique, beta2-microglobulin was found to be localized along tubular and glomerular basement membranes of renal bipsies studied. Since beta2-microglobulin is a subunit of HLA preparations, it may also serve as an indirect marker for the presence of...

journal_title：Transplantation

authors： Ooi BS,Rubin SC,Pesce AJ,Pollak VE

更新日期：1977-07-01 00:00:00