Histological evidence of delayed ischemic brain tissue damage in the rat double-hemorrhage model.

abstract：:Churg-Strauss syndrome (CSS) is a rare systemic vasculitis, almost invariably accompanied by asthma, nasal polyposis, paranasal sinus abnormalities, and increased peripheral blood eosinophil count. Neurological involvement as peripheral neuropathy is a common feature, whereas cerebral involvement is extremely rare. He...

journal_title：Journal of the neurological sciences

authors： Mencacci NE,Bersano A,Cinnante CM,Ciammola A,Corti S,Meroni PL,Silani V

更新日期：2011-02-15 00:00:00

abstract：:Focal spinal cord blood flow was measured in the left dorsal column during left sciatic nerve stimulation, and compared to blood flow in the same area during sciatic nerve inactivity. Blood flow was found to be significantly increased during stimulation. It is suggested that this increased blood flow is a reflection o...

journal_title：Journal of the neurological sciences

authors： Kobrine AI,Evans DE,Rizzoli HV

更新日期：1978-10-01 00:00:00

abstract：:Two methods for the investigation of oligoclonal immunoglobulin bands in cerebrospinal fluid are compared. Isoelectric focusing (IEF) in agarose gels combined with a highly sensitive affinity immunoblotting proved to be superior to PAGE-IEF and silver staining regarding detection sensitivity and expenditure of labour....

journal_title：Journal of the neurological sciences

authors： Kaiser R

更新日期：1991-06-01 00:00:00

abstract：:Leucine-rich repeats and immunoglobulin-like domains (LRIG) 3 gene is mapped to chromosome 12q13.2, a region that is frequently deleted in a subset of glioblastoma multiforme (GBM). It has been reported that perinuclear LRIG3 staining correlated with low WHO grade of glioma and better survival of the patients. However...

journal_title：Journal of the neurological sciences

authors： Guo D,Yang H,Guo Y,Xiao Q,Mao F,Tan Y,Wan X,Wang B,Lei T

更新日期：2015-03-15 00:00:00

abstract：:We have determined various biomarkers in the peripheral blood of Alzheimer, Parkinson and vascular dementia patients by comparing the samples with those of first-degree relatives and control subjects. Our results, together with correlation studies using data from the Mini-Mental State Examination (MMSE), suggest that ...

journal_title：Journal of the neurological sciences

authors： Cristalli DO,Arnal N,Marra FA,de Alaniz MJ,Marra CA

更新日期：2012-03-15 00:00:00

abstract：:The Hyper-IgE syndrome (HIES) is a rare primary immunodeficiency which recently has been associated with heterozygous dominant-negative mutations in the signal transducer and activator of transcription 3 (STAT3). Although HIES is characterized by recurrent staphylococcal infections, the microbial invasion of the centr...

journal_title：Journal of the neurological sciences

authors： Beitzke M,Enzinger C,Windpassinger C,Pfeifer D,Fazekas F,Woellner C,Grimbacher B,Kroisel PM

更新日期：2011-10-15 00:00:00

abstract：BACKGROUND:Clinical data across the globe especially in genetic diseases like Huntington's disease (HD) is most helpful when collected using standardized formats. This helps in proper comparison of clinical and genetic data. METHODS:Herein, we report clinical data on 26 genetically confirmed HD patients from 19 Indian...

journal_title：Journal of the neurological sciences

authors： Murgod UA,Saleem Q,Anand A,Brahmachari SK,Jain S,Muthane UB

更新日期：2001-09-15 00:00:00

abstract：PURPOSE:To assess whether clonal IgH genes in CSF of patients with CNS lymphoma correlates with the disease course. BACKGROUND:It has been shown that the PCR technique, which offers a sensitive test for diagnosis of systemic lymphoproliferative malignancies, can be applied to the CSF. METHODS:Seventy-three CSF specim...

journal_title：Journal of the neurological sciences

authors： Ekstein D,Ben-Yehuda D,Slyusarevsky E,Lossos A,Linetsky E,Siegal T

更新日期：2006-08-15 00:00:00

abstract：:In our study, mitochondria were isolated from skeletal muscle in 2-, 3-, 4-, 6-, 8-, and 12-week-old normal (C57BL6j dy/+), and 4-, 8-, and 12-week-old dystrophic (C57BL6j dy/dy) mice and in normal subjects and patients with Duchenne or Becker muscular dystrophy. A deficit was observed in a calcium-specific mitochondr...

journal_title：Journal of the neurological sciences

authors： Lucas-Héron B,Mussini JM,Ollivier B

更新日期：1989-05-01 00:00:00

abstract：BACKGROUNDS:Although prevention of hematoma enlargement and thromboembolic complications is critically important in acute intracerebral hemorrhage (ICH) patients with prosthetic heart valves, clinical data are scarce. The goal of this study was to elucidate patient characteristics, acute treatments, and the clinical co...

journal_title：Journal of the neurological sciences

authors： Nishimura K,Koga M,Minematsu K,Takahashi JC,Nagatsuka K,Kobayashi J,Toyoda K

更新日期：2016-04-15 00:00:00

abstract：:Hereditary motor and sensory neuropathy (HMSN), also known as Charcot-Marie-Tooth disease (CMT) is a group of clinically and genetically heterogeneous neuropathies classically divided into demyelinating (CMT1) and axonal forms (CMT2). The most common demyelinating form is CMT1A with an underlying duplication in the ge...

journal_title：Journal of the neurological sciences

authors： Zschüntzsch J,Dibaj P,Pilgram S,Kötting J,Gerding WM,Neusch C

更新日期：2009-06-15 00:00:00

abstract：INTRODUCTION:To evaluate the non-ataxic clinical manifestations in genetically proven Spinocerebellar ataxia 2 (SCA2) and identify their determinants and predictors. METHODS:Seventy-three subjects with genetically proven SCA2 were evaluated clinically for the common non-ataxic manifestations. Based on the presence or ...

journal_title：Journal of the neurological sciences

authors： Stezin A,Venkatesh SD,Thennarasu K,Purushottam M,Jain S,Yadav R,Pal PK

更新日期：2018-11-15 00:00:00

abstract：OBJECTIVE:To identify the main determinants of health-related quality of life (HRQoL) in Brazilian stroke survivors. METHODS:Patients were assessed with the NIH Stroke Scale, Barthel index (BI), Lawton scale, modified-Rankin scale, Cumulative Illness Rating Scale for Geriatrics, Mini-Mental State Examination, Hospital...

journal_title：Journal of the neurological sciences

authors： Carod-Artal FJ,Trizotto DS,Coral LF,Moreira CM

更新日期：2009-09-15 00:00:00

abstract：:The onset of multiple sclerosis presents in 85% of cases as a subacute clinical event, the so-called clinically isolated syndrome. This event involves either focal or multifocal brain regions, most frequently the optic nerve, brainstem or spinal cord. The initial diagnosis of multiple sclerosis necessitates the demons...

journal_title：Journal of the neurological sciences

authors： Tumani H,Sapunova-Mayer I,Süssmuth SD,Hirt V,Brettschneider J

更新日期：2009-12-01 00:00:00

abstract：:Neuronal damage seems to be a major source of disability in multiple sclerosis (MS) patients and at present magnetic resonance imaging (MRI) is a sensitive method to evaluate lesion and disease activity. We studied the potential correlation between changes in MS patients' disability after relapse, the degree of T1 les...

journal_title：Journal of the neurological sciences

authors： Cid C,Alcázar A,Regidor I,Masjuan J,Salinas M,Alvarez-Cermeño JC

更新日期：2002-01-15 00:00:00

abstract：:We have analyzed the serum from patients with refractory epilepsy for the presence of autoreactive antibodies to AMPA glutamate receptor subunits. The presence and the level of autoantibodies were assessed using immunoblot and ELISA with synthetic peptides specific for subregions of AMPA glutamate receptor subunits. P...

journal_title：Journal of the neurological sciences

authors： Dambinova SA,Izykenova GA,Burov SV,Grigorenko EV,Gromov SA

更新日期：1997-11-06 00:00:00

abstract：:This study evaluated the effect of low-level laser therapy (LLLT; 15 J/cm(2)) and a latex protein (F1) on a crush injury of the sciatic (ischiadicus) nerve. Seventy-two rats (male, 250 g) were divided into 6 groups: CG, control; EG, exposed nerve; IG, injured nerve without treatment; LG, injured nerve with LLLT; HG, i...

journal_title：Journal of the neurological sciences

authors： Dias FJ,Issa JP,Coutinho-Netto J,Fazan VP,Sousa LG,Iyomasa MM,Papa PC,Watanabe IS

更新日期：2015-02-15 00:00:00

abstract：:Nineteen patients with Motor Neurone Disease (MND) who had been living with their partners for at least two years prior to the onset of their illness, together with their partners, completed self-report questionnaires to investigate the impact of MND on both patients and carers. Physical disability and impact of the i...

journal_title：Journal of the neurological sciences

authors： Goldstein LH,Adamson M,Jeffrey L,Down K,Barby T,Wilson C,Leigh PN

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:CYP2D6 gene encoding CYP2D6 enzyme belonging to the cytochrome P450 system has aroused long attention being a candidate gene for Alzheimer's disease (AD), but the results remain inconsistent and underpowered. OBJECTIVES:To investigate the contradictory results, the effect of single CYP2D6 polymorphism- CYP2...

journal_title：Journal of the neurological sciences

authors： Lu Y,Qin X,Li S,Zhang X,He Y,Peng Q,Deng Y,Wang J,Xie L,Li T,Zeng Z

更新日期：2014-08-15 00:00:00

abstract：:Mutations in COL4A1, encoding one of the six collagen type IV proteins, cover a wide spectrum of autosomal dominant overlapping phenotypes including porencephaly, small-vessel disease and hemorrhagic stroke, leukoencephalopathy, hereditary angiopathy with nephropathy, aneurysms and muscle cramp (HANAC) syndrome, and W...

journal_title：Journal of the neurological sciences

authors： Giorgio E,Vaula G,Bosco G,Giacone S,Mancini C,Calcia A,Cavalieri S,Di Gregorio E,Rigault De Longrais R,Leombruni S,Pinessi L,Cerrato P,Brusco A,Brussino A

更新日期：2015-05-15 00:00:00

abstract：PURPOSE:This study aimed to evaluate the risk factors, etiology, and outcomes of ischemic stroke (IS) in Japanese young adults. METHODS:This was a prospective multicenter study. We enrolled patients aged 16 to 55 years with IS within seven days of the onset of symptoms. We assessed the demographic data, risk factors, ...

journal_title：Journal of the neurological sciences

authors： Kono Y,Terasawa Y,Sakai K,Iguchi Y,Nishiyama Y,Nito C,Suda S,Kimura K,Kanzawa T,Imafuku I,Nakayama T,Ueda M,Iwanaga T,Kono T,Yamashiro K,Tanaka R,Okubo S,Nakajima M,Nakajima N,Mishina M,Yaguchi H,Oka H,Suzuki

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:Multiple sclerosis (MS) patients commonly suffer from fatigue and define it as one of their most disabling symptom profoundly disrupting their lives. However, the relationship of fatigue to cognitive functions and its impact on quality of life have not been widely studied. AIM:To define (1) "cognitive fatig...

journal_title：Journal of the neurological sciences

authors： Barak Y,Achiron A

更新日期：2006-06-15 00:00:00

abstract：:We studied the effects of fasudil, a selective Rho-kinase inhibitor, on experimental autoimmune neuritis (EAN). Continuous parenteral administration of fasudil prevented the development of EAN induced by P0 peptide 180-199 in Lewis rats while it also reduced EAN severity when administered after disease onset. Immunohi...

journal_title：Journal of the neurological sciences

authors： Pineda AA,Minohara M,Kawamura N,Matsushita T,Yamasaki R,Sun X,Piao H,Shimokawa H,Kira J

更新日期：2011-07-15 00:00:00

abstract：:Hemifacial spasm is characterised by unilateral contractions of the facial muscles. Though considered to be benign by many people, it can lead to functional blindness and a poor quality of life due to social embarrassment for the suffering individual. Botulinum toxin therapy is an excellent noninvasive tool to treat t...

journal_title：Journal of the neurological sciences

authors： Chaudhry N,Srivastava A,Joshi L

更新日期：2015-09-15 00:00:00

abstract：:Forty-three patients with Parkinson's disease (PD) and thirty-seven normal volunteers were subjected to clinical, neuropsychological, neurophysiological (P300 component of the event-related potentials ERP) and radiological (cranial computerized tomographic scanning CCT) evaluation. Intentional memory was more impaired...

journal_title：Journal of the neurological sciences

authors： Elwan OH,Baradah OH,Madkour O,Elwan H,Hassan AA,Elwan F,Mahfouz M,Ali A,Fahmy M

更新日期：1996-11-01 00:00:00

abstract：:We report the clinical, neuropsychological, and neuroimaging findings of two patients of diffuse encephalopathy associated with the use of metronidazole. Both patients showed characteristic abnormalities on magnetic resonance imaging (MRI) with diffusion weighted imaging (DWI) and recovered incompletely after the disc...

journal_title：Journal of the neurological sciences

authors： Kim DW,Park JM,Yoon BW,Baek MJ,Kim JE,Kim S

更新日期：2004-09-15 00:00:00

abstract：:A multitude of factors must be overcome following spinal cord injury (SCI) in order to achieve clinical improvement in patients. It is thought that by combining promising therapies these diverse factors could be combatted with the aim of producing an overall improvement in function. Chondroitin sulphate proteoglycans ...

journal_title：Journal of the neurological sciences

authors： Carwardine D,Wong LF,Fawcett JW,Muir EM,Granger N

更新日期：2016-08-15 00:00:00

abstract：:Differentiating Parkinson's disease (PD) from other types of neurodegenerative atypical parkinsonism (AP) can be challenging, especially in early disease stages. Routine brain magnetic resonance imaging (MRI) can show atrophy or signal changes in several parts of the brain with fairly high specificity for particular f...

journal_title：Journal of the neurological sciences

authors： Meijer FJ,Bloem BR,Mahlknecht P,Seppi K,Goraj B

更新日期：2013-09-15 00:00:00

abstract：:In order to support the concept that a lesion of the thalamus is sufficient to cause a Korsakoff syndrome, we are presenting 5 patients, all of whom developed the syndrome after sustaining a left (dominant) thalamic infarction. Two patients had pure thalamic strokes followed by a permanent Korsakoff syndrome. One of t...

journal_title：Journal of the neurological sciences

authors： Cole M,Winkelman MD,Morris JC,Simon JE,Boyd TA

更新日期：1992-07-01 00:00:00

abstract：:In view of recent reports on lower brainstem dysfunction in Huntington's chorea, we studied respiration during sleep in 12 patients with Huntington's chorea (HC) and in controls. There were no statistically significant differences between patients and controls with respect to apnea periods, respiratory frequency and t...

journal_title：Journal of the neurological sciences

authors： Bollen EL,Den Heijer JC,Ponsioen C,Kramer C,Van der Velde EA,Van Dijk JG,Roos RA,Kamphuisen HA,Buruma OJ

更新日期：1988-03-01 00:00:00