Abstract：
:Bacterial vaginosis (BV) is a commonly occurring vaginal infection that is associated with a variety of serious risks related to the reproductive health of women. Conventional antibiotic treatment for this condition is frequently ineffective because the antibiotics tend to inhibit healthy vaginal microflora along with the pathogens. Lactocin 160, a bacteriocin produced by healthy vaginal lactobacilli, is a promising alternative to antibiotics; this compound specifically inhibits the BV-associated vaginal pathogens such as Gardnerella vaginalis and Prevotella bivia without affecting the healthy microflora. This study investigates the molecular mechanism of action for lactocin 160 and reveals that this compound targets the cytoplasmic membrane of G. vaginalis, causing the efflux of ATP molecules and dissipation of the proton motive force.
journal_name
Probiotics Antimicrob Proteinsjournal_title
Probiotics and antimicrobial proteinsauthors
Turovskiy Y,Ludescher RD,Aroutcheva AA,Faro S,Chikindas MLdoi
10.1007/s12602-008-9003-6subject
Has Abstractpub_date
2009-01-20 00:00:00pages
67-74issue
1eissn
1867-1306issn
1867-1314journal_volume
1pub_type
杂志文章abstract：:Lipopolysaccharide (LPS) is a toxic and immunogenic agent for human. Additionally, LPS is a good target for some antimicrobial compounds, including antimicrobial peptides (AMPs). LPS-binding peptides (LBPs) can recognize and neutralize LPS. Rabbit and human cathelicidins are AMPs with LPS-binding activity. In this stu...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-020-09648-5
更新日期：2020-12-01 00:00:00
abstract：:The present study was conducted to investigate the effects of probiotic and encapsulated Lactobacillus bulgaricus on hematological and immunological factors after lead toxicity in rainbow trout (Oncorhynchus mykiss). Two hundred and forty fish weighing about 16 ± 3.8 g were divided randomly in to four groups including...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-019-09544-7
更新日期：2020-06-01 00:00:00
abstract：:Three halotolerant lactobacilli (Lactobacillus plantarum, L. pentosus, and L. acidipiscis) isolated from a ripened Mexican tropical cheese (double cream Chiapas cheese) were evaluated as potential probiotics and compared with two commercial probiotic strains (L. casei Shirota and L. plantarum 299v) from human origin. ...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-013-9144-0
更新日期：2013-12-01 00:00:00
abstract：:Growth behavior and production of short-chain fatty acid (SCFA) of two probiotics, Pediococcus acidilactici and Lactococcus lactis, each at 107 cfu/g (P1, L1) and 1010 cfu/g (P2, L2) at different concentrations of fructooligosaccharide (FOS) [0.5% (F1), 1% (F2), and 2% (F3)] were assessed in vitro. The time to reach t...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-018-9462-3
更新日期：2019-09-01 00:00:00
abstract：:The ability of a probiotic strain (Weissella cibaria) to adhere on tissue and the effect of its topical application in nipples of lactating cows on physicochemical characteristics of milk were evaluated. An ex vivo model was used to demonstrate the adhesion capacity of W. cibaria. Tissue samples were randomly distribu...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-018-9481-0
更新日期：2019-12-01 00:00:00
abstract：:Bacillus cereus strain F, collected from relict permafrost located in Siberia, was analyzed for probiotic activity in the mouse Salmonella enterica model. Viable bacterial cells were found in frozen soils taken at Mammoth Mountain in Yakutia from a depth below the level of seasonal thawing. Geological data indicated t...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-012-9105-z
更新日期：2012-09-01 00:00:00
abstract：:The use of natural products together with standard antimicrobial drugs has recently received more attention as a strategy to combat infectious diseases caused by multidrug-resistant (MDR) microorganisms. This study aimed to evaluate the capacity of a galactose-binding lectin from Vatairea macrocarpa seeds (VML) to mod...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-019-9526-z
更新日期：2020-03-01 00:00:00
abstract：:The purpose of this article is to reveal the role of the lactic acid bacteria (LAB) in the beebread transformation/preservation, biochemical properties of 25 honeybee endogenous LAB strains, particularly: antifungal, proteolytic, and amylolytic activities putatively expressed in the beebread environment have been stud...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-017-9379-2
更新日期：2018-12-01 00:00:00
abstract：:Probiotics are a nutritional tool for disease prevention. It has been proposed that stimulation of immune response could affect the growth-promoting properties of antimicrobial growth promoters as well as the control of foodborne pathogens. The current study compares immune response in the blood of 280 non-infected an...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-010-9054-3
更新日期：2010-10-01 00:00:00
abstract：:The original version of this article contained mistakes, and the authors would like to correct them. The correct details are given below. ...
journal_title：Probiotics and antimicrobial proteins
pub_type： 已发布勘误
doi：10.1007/s12602-018-9412-0
更新日期：2019-06-01 00:00:00
abstract：:Antimicrobial peptides (AMPs) are compounds widely distributed in nature that display activity against a broad spectrum of pathogens. Amphibian skin, as an organ rich in pharmacologically active peptides, appears to be an interesting source of novel AMPs. Aurein 1.2 (GLFDIIKKIAESF-NH2) is a short 13-residue antimicrob...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-018-9501-0
更新日期：2019-09-01 00:00:00
abstract：:The aim of this work is to characterize the potential probiotic properties of 14 antifungal Lactobacillus strains isolated from traditional fermenting Moroccan green olives. The molecular identification of strains indicated that they are composed of five Lactobacillus brevis, two Lactobacillus pentosus, and seven Lact...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-019-09543-8
更新日期：2020-06-01 00:00:00
abstract：:The present study was conducted to assess the effects of combined and singular dietary administration of PrimaLac® and potassium diformate (KDF) on growth performance, feed utilization, digestive enzymes activity, and some physiological parameters of rainbow trout (Oncorhynchus mykiss) juvenile. Three hundred sixty ra...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-019-9523-2
更新日期：2020-03-01 00:00:00
abstract：:The effect of two putative probiotic strains, Lactobacillus rhamnosus BFE5264 and Lactobacillus plantarum NR74, on the control of cholesterol efflux in enterocytes was assessed by focusing on the promotion of ATP-binding cassette sub-family G members 5 and 8 (ABCG5 and ABCG8). Differentiated Caco-2 enterocytes were tr...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-011-9086-3
更新日期：2011-12-01 00:00:00
abstract：:Artisanal fermented beverages have been associated with beneficial effects for a long time. In Mexico, there are a wide variety of artisanal fermented beverages such as Tepache, where the fermentation is initiated by the addition of grains of a polysaccharide-containing biofilm matrix formed by a symbiotic association...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-018-9471-2
更新日期：2019-09-01 00:00:00
abstract：:IL-17A is a cytokine which is produced by several immune and non-immune cells. The cytokine plays dual roles from protection from microbes and protection from pro-inflammatory based diseases to induction of the pro-inflammatory based diseases. The main mechanisms which lead to the controversial roles of IL-17A are yet...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章,评审
doi：10.1007/s12602-017-9329-z
更新日期：2019-03-01 00:00:00
abstract：:Thaumatin-like proteins (TLPs) are the products of a large, highly complex gene family involved in host defense. TLPs also belong to the pathogenesis-related family 5 (PR-5) of plant defense proteins. Most TLPs exhibit potential antifungal activities, and their accumulation in the plant is related to many physiologica...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-018-9422-y
更新日期：2019-03-01 00:00:00
abstract：:Information regarding cellular anti-senescence attributes of probiotic bacteria vis-à-vis modulation of senescence-associated secretory phenotype (SASP) and mTOR signaling is very limited. The present study assessed anti-senescence potential of secretory metabolites of probiotic Lactobacillus fermentum (Lact. fermentu...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-019-09576-z
更新日期：2020-06-01 00:00:00
abstract：:Plantaricin 423, produced by Lactobacillus plantarum 423, was encapsulated in nanofibers that were produced by the electrospinning of 18% (w/v) polyethylene oxide (200 000 Da). The average diameter of the nanofibers was 288 nm. Plantaricin 423 activity decreased from 51 200 AU/ml to 25 600 AU/ml and from 204 800 AU/ml...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-009-9024-9
更新日期：2010-03-01 00:00:00
abstract：:Oysters hold a unique place within the field of aquaculture as one of the only organisms that is regularly shipped live to be consumed whole and raw. The microbiota of oysters is capable of adapting to a wide range of environmental conditions within their dynamic estuarine environments; however, human aquaculture prac...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章,评审
doi：10.1007/s12602-019-09629-3
更新日期：2020-06-01 00:00:00
abstract：:This review focuses on the structure and mode-of-action of the two-peptide (class-IIb) bacteriocins that consist of two different peptides whose genes are next to each other in the same operon. Optimal antibacterial activity requires the presence of both peptides in about equal amounts. The two peptides are synthesize...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-009-9021-z
更新日期：2010-03-01 00:00:00
abstract：:Unveiling and understanding differences in physiological features below the species level may serve as an essential fast-screening tool for selecting strains that can promote a specific probiotic effect. To study the intra-species diversity of Bacillus, a genus with a wide range of enzyme activities and specificity, 1...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-020-09672-5
更新日期：2020-06-30 00:00:00
abstract：:The neutral outcome of the recently reported school-based trial of probiotic K12 (The effect of the oral probiotic Streptococcus salivarius K12 on group A streptococcus pharyngitis: a pragmatic trial in schools) can be attributed at least partially to several readily identifiable confounding factors. Mainly, the execu...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-018-9398-7
更新日期：2019-03-01 00:00:00
abstract：:Alcoholic liver disease (ALD) encompasses a broad spectrum of disorders including steatosis, steatohepatitis, fibrosis, and cirrhosis. Despite intensive research in the last two decades, there is currently no Food and Drug Administration-approved therapy for treating ALD. Several studies have demonstrated the importan...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-018-9419-6
更新日期：2019-06-01 00:00:00
abstract：:Hepcidins are small cysteine-rich antimicrobial peptides that play an important role in fish immunity against pathogens. Most fish species have two or more hepcidin homologs that have distinct functions. This study investigated the immune functions of mudskipper (Boleophthalmus pectinirostris) hepcidin-1 (BpHep-1) and...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-017-9352-0
更新日期：2018-06-01 00:00:00
abstract：:Helicobacter pylori is an infectious agent commonly associated with gastrointestinal diseases. The use of probiotics to treat this infection has been documented, however, their potential antimicrobial metabolites have not yet been investigated. In the present study, the effect of reuterin produced by Lactobacillus reu...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-017-9342-2
更新日期：2018-06-01 00:00:00
abstract：:A Bacillus-based direct-fed microbial (DFM), Omni-BosCB™, added to an electrolyte was evaluated as a therapy for scours. Fecal shedding of presumptive Clostridium perfringens at day 7 was reduced in scouring calves treated with electrolyte plus DFM compared to scouring calves treated with electrolyte alone. Total ther...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-008-9004-5
更新日期：2009-06-01 00:00:00
abstract：:It has been recently shown, that certain strains/isolates of Bacillus subtilis can be used as a probiotic for humans. The production of the macrocyclic sactibiotic subtilosin in B. subtilis ATCC 6633 is highly regulated. To improve the subtilosin productivity of B. subtilis, different growth conditions were compared f...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-019-09547-4
更新日期：2020-06-01 00:00:00
abstract：:Axone (Akhuni) is a homemade synbiotic (Nagamese fermented soybean product) served as side dish in North Eastern India. In this study, effects of Axone feeding on growth, weight gain, sexual maturity and egg production on Vanaraja birds (a strain of poultry bird developed at PDP Hyderabad for villages and backyard pou...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-014-9160-8
更新日期：2014-06-01 00:00:00
abstract：:The effects of treatment with probiotics on the immunological and hematobiochemical changes in Trypanosoma brucei infection were investigated. Probiotic strains used are Bifidobacterium BB-12, Lactobacillus acidophilus LA-5, Lactobacillus delbrueckii LBY-27, Lactobacillus paracasei LC-01, and Streptococcus thermophilu...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-019-09592-z
更新日期：2020-09-01 00:00:00
