Abstract：
:Unveiling and understanding differences in physiological features below the species level may serve as an essential fast-screening tool for selecting strains that can promote a specific probiotic effect. To study the intra-species diversity of Bacillus, a genus with a wide range of enzyme activities and specificity, 190 Bacillus strains were isolated from traditional Korean fermented food products. Altogether, in the preliminary safety screening, 8 of these strains were found negative for lecithinase and hemolysis activity and were selected for further investigations. On the basis of different levels of enzyme functionalities (high or low proteolytic, amylolytic, and lipolytic (PAL) activities), two Bacillus subtilis strains were selected for an in vivo study. Each of the two strains was separately administered at a level of 1 × 108 CFU per day to C57BL/6 mice that were fed 60% high-fat diet ad libitum for 8 weeks, while Xenical, an anti-obesity drug, was used as a positive control in the experimental setup. B. subtilis M34 and B. subtilis GS40a with low and high amylolytic activities, respectively, induced significantly different and contrasting physiological effects. The production of short-chain fatty acids appeared to be closely associated with a shift in the gut microbiota.
journal_name
Probiotics Antimicrob Proteinsjournal_title
Probiotics and antimicrobial proteinsauthors
Park H,Lee M,Jeong D,Park S,Ji Y,Todorov SD,Holzapfel WHdoi
10.1007/s12602-020-09672-5subject
Has Abstractpub_date
2020-06-30 00:00:00eissn
1867-1306issn
1867-1314pii
10.1007/s12602-020-09672-5pub_type
杂志文章abstract：:Lactiplantibacillus plantarum subsp. plantarum 299v (L. plantarum 299v) is one of the most important probiotic strains in animal health, but the molecular mechanisms of how it exerts health benefits remain unclear. The purpose of this study was to explore the changes in miRNA expression profiles in the intestinal tiss...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-021-09743-1
更新日期：2021-01-24 00:00:00
abstract：:Twenty-nine Lactobacillus plantarum strains isolated from different types of Polish regional cheeses (Oscypek and Korycinski) were assessed for selected probiotic properties and anti-staphylococcal activity. Most of the tested L. plantarum strains were considered safe. Whole bacterial cultures (WBC) and cell-free supe...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-019-09587-w
更新日期：2020-09-01 00:00:00
abstract：:Thaumatin-like proteins (TLPs) are the products of a large, highly complex gene family involved in host defense. TLPs also belong to the pathogenesis-related family 5 (PR-5) of plant defense proteins. Most TLPs exhibit potential antifungal activities, and their accumulation in the plant is related to many physiologica...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-018-9422-y
更新日期：2019-03-01 00:00:00
abstract：:The wide spread of antimicrobial resistance has urged the need of alternative therapeutic approach. In this context, probiotic lactobacilli have been reported for the prevention and treatment of many gastrointestinal and urogenital infections. However, very little is known about their antagonistic activity against ski...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-013-9137-z
更新日期：2013-09-01 00:00:00
abstract：:The neutral outcome of the recently reported school-based trial of probiotic K12 (The effect of the oral probiotic Streptococcus salivarius K12 on group A streptococcus pharyngitis: a pragmatic trial in schools) can be attributed at least partially to several readily identifiable confounding factors. Mainly, the execu...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-018-9398-7
更新日期：2019-03-01 00:00:00
abstract：:The effect of a prebiotic (fructooligosaccharides) or a synbiotic components (prebiotic and probiotic) on the viability, proteolysis and antioxidant properties of probiotic and synbiotic yogurt during 28 days of storage at 4 °C has been investigated. Yogurt starters in conjunction with either probiotic bacteria Lactob...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-012-9099-6
更新日期：2012-06-01 00:00:00
abstract：:Oxidative stress plays an important role in exacerbating neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. In a previous study, Lactobacillus plantarum 200655 was shown to possess probiotic and antioxidant potential. The current study aimed to evaluate the neuropro...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-020-09740-w
更新日期：2021-01-17 00:00:00
abstract：:High-fat diet (HFD) consumption induces obesity and increases blood glucose, insulin resistance, and metabolic disorders. Recent studies suggest that probiotics might be a novel approach to counteract these effects in the treatment of obesity. Here, we evaluated the effect of Leuconostoc mesenteroides subsp. mesentero...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-019-09556-3
更新日期：2020-06-01 00:00:00
abstract：:Bacillus cereus strain F, collected from relict permafrost located in Siberia, was analyzed for probiotic activity in the mouse Salmonella enterica model. Viable bacterial cells were found in frozen soils taken at Mammoth Mountain in Yakutia from a depth below the level of seasonal thawing. Geological data indicated t...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-012-9105-z
更新日期：2012-09-01 00:00:00
abstract：:Bacterial vaginosis (BV) is a commonly occurring vaginal infection that is associated with a variety of serious risks related to the reproductive health of women. Conventional antibiotic treatment for this condition is frequently ineffective because the antibiotics tend to inhibit healthy vaginal microflora along with...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-008-9003-6
更新日期：2009-01-20 00:00:00
abstract：:Ovarian cancer (OC) is a leading cause of death among women worldwide. Various evidences suggest that oncomiRs and Toll-like receptor 4 (TLR-4) signaling pathways appear to be key players in the initiation and progression of OC. It seems there exists a continuous intercommunication between cancer cells and normal micr...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-019-09596-9
更新日期：2020-09-01 00:00:00
abstract：:Helicobacter pylori is an infectious agent commonly associated with gastrointestinal diseases. The use of probiotics to treat this infection has been documented, however, their potential antimicrobial metabolites have not yet been investigated. In the present study, the effect of reuterin produced by Lactobacillus reu...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-017-9342-2
更新日期：2018-06-01 00:00:00
abstract：:IL-17A is a cytokine which is produced by several immune and non-immune cells. The cytokine plays dual roles from protection from microbes and protection from pro-inflammatory based diseases to induction of the pro-inflammatory based diseases. The main mechanisms which lead to the controversial roles of IL-17A are yet...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章,评审
doi：10.1007/s12602-017-9329-z
更新日期：2019-03-01 00:00:00
abstract：:A specific strain of naturally occurring oral lactobacilli was isolated and identified based on morphological, biochemical, and 16S rRNA gene sequencing. The phylogenetic affiliation of the isolate confirmed that the NK02 strain had close association with the Lactobacillus salivarius. An effective mouthwash was develo...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章,随机对照试验
doi：10.1007/s12602-017-9296-4
更新日期：2018-09-01 00:00:00
abstract：:The ability of a probiotic strain (Weissella cibaria) to adhere on tissue and the effect of its topical application in nipples of lactating cows on physicochemical characteristics of milk were evaluated. An ex vivo model was used to demonstrate the adhesion capacity of W. cibaria. Tissue samples were randomly distribu...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-018-9481-0
更新日期：2019-12-01 00:00:00
abstract：:The administration of probiotics is a promising approach to reduce the prevalence of colon cancer, a multifactorial disease, with hereditary factors, as well as environmental lifestyle-related risk factors. Biogenic polyamines, putrescine, spermidine, and spermine are small cationic molecules with great roles in cell ...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-017-9253-2
更新日期：2017-06-01 00:00:00
abstract：:The effects of treatment with probiotics on the immunological and hematobiochemical changes in Trypanosoma brucei infection were investigated. Probiotic strains used are Bifidobacterium BB-12, Lactobacillus acidophilus LA-5, Lactobacillus delbrueckii LBY-27, Lactobacillus paracasei LC-01, and Streptococcus thermophilu...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-019-09592-z
更新日期：2020-09-01 00:00:00
abstract：:Emerging evidence suggests that probiotic therapy can play a role in the prevention and management of oral inflammatory diseases through immunomodulation and down-regulation of the inflammatory cascade. The aim of this in vitro study was to investigate the viability of human gingival fibroblasts (HGF) and its producti...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-016-9246-6
更新日期：2017-09-01 00:00:00
abstract：:Food-grade yeasts make significant contributions to flavor development in fermented foods. Some yeast species also inhibit undesirable bacteria, yeasts and molds, apparently by producing antimicrobial compounds called mycocins. The aim of this study was to evaluate the ability of wild yeasts, isolated from raw milk an...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-012-9109-8
更新日期：2013-03-01 00:00:00
abstract：:In this work, we performed the rational design of a cationic antimicrobial peptide, GIBIMPY4, using the software DEPRAMPs developed at the GIBIM research group. GIBIMPY4 has a length of 17 amino acids, it is amphipathic, its structure is α-helix and it has a net charge of (+5). Solid-phase peptide synthesis was perfor...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-016-9219-9
更新日期：2016-09-01 00:00:00
abstract：:Dental diseases are among the common health issues experienced around the world. Dental caries is one of the most predominant oral diseases worldwide. Major factors associated with caries development include poor oral hygiene, the content of specific carbohydrates in the diet, dental biofilm formation, the cariogenic ...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章,评审
doi：10.1007/s12602-020-09652-9
更新日期：2020-12-01 00:00:00
abstract：:The aim of this work is to characterize the potential probiotic properties of 14 antifungal Lactobacillus strains isolated from traditional fermenting Moroccan green olives. The molecular identification of strains indicated that they are composed of five Lactobacillus brevis, two Lactobacillus pentosus, and seven Lact...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-019-09543-8
更新日期：2020-06-01 00:00:00
abstract：:Probiotics offer numerous health benefits, including digestive and immune health. Improved digestive health is linked to a more efficient absorption of important nutrients from our diet. This review focused on the rationale of using the probiotic Bacillus coagulans GBI-30, 6086 to aid protein absorption and utilizatio...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章,评审
doi：10.1007/s12602-017-9354-y
更新日期：2018-12-01 00:00:00
abstract：:Microbial diseases in fish, plant, animal and human are rising constantly; thus, discovery of their antidote is imperative. The use of antibiotic in aquaculture further compounds the problem by development of resistance and consequent consumer health risk by bio-magnification. Antimicrobial peptides (AMPs) have been h...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-016-9215-0
更新日期：2016-09-01 00:00:00
abstract：:The probiotic effect of Enterococcus faecalis-1 (isolated from healthy chickens) on growth performance, immune response, and modulation of the intestinal microbiota of broilers was assessed with a total of 100-day-old commercial Cobb chicks. The chicks were randomly divided into two equal groups. The control group rec...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-019-09557-2
更新日期：2020-06-01 00:00:00
abstract：:The original version of this article contained mistakes, and the authors would like to correct them. The correct details are given below. ...
journal_title：Probiotics and antimicrobial proteins
pub_type： 已发布勘误
doi：10.1007/s12602-018-9412-0
更新日期：2019-06-01 00:00:00
abstract：:It is well established that bacteria communicate between each other by using different mechanisms; among which, quorum sensing (QS) is the best known one. Indeed, intra- and intercellular communications of microorganisms, as well as the regulation of metabolism and reaction to the surrounding environmental conditions,...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章,评审
doi：10.1007/s12602-019-09555-4
更新日期：2020-03-01 00:00:00
abstract：:Urinary tract infections (UTIs) are the most common infectious diseases in infants and the elderly; they are also the most common among nosocomial infections. The treatment of UTIs usually involves a short-term course of antibiotics. The purpose of this study was to identify the strains of lactic acid bacteria (LAB) t...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-017-9302-x
更新日期：2018-06-01 00:00:00
abstract：:To screen Bacillus clausii UBBC07 as a putative probiotic strain and to examine the protective effect of probiotic-B. clausii UBBC07 spore on uremia on rats induced by acetaminophen. In vitro tests performed to screen potential probiotic strains were gastric and bile acid resistance and ability to reduce pathogen adhe...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-019-09540-x
更新日期：2020-03-01 00:00:00
abstract：:Three halotolerant lactobacilli (Lactobacillus plantarum, L. pentosus, and L. acidipiscis) isolated from a ripened Mexican tropical cheese (double cream Chiapas cheese) were evaluated as potential probiotics and compared with two commercial probiotic strains (L. casei Shirota and L. plantarum 299v) from human origin. ...
journal_title：Probiotics and antimicrobial proteins
pub_type： 杂志文章
doi：10.1007/s12602-013-9144-0
更新日期：2013-12-01 00:00:00
