Abstract:
:The circadian clock enhances fitness through temporal organization of plant gene expression, metabolism and physiology. Two recent studies, one in BMC Evolutionary Biology, demonstrate through phylogenetic analysis of the CCA1/LHY and TOC1/PRR gene families that the common ancestor of monocots and eudicots had components sufficient to construct a circadian clock consisting of multiple interlocked feedback loops.
journal_name
BMC Bioljournal_title
BMC biologyauthors
McClung CRdoi
10.1186/1741-7007-8-55subject
Has Abstractpub_date
2010-05-07 00:00:00pages
55issn
1741-7007pii
1741-7007-8-55journal_volume
8pub_type
评论,杂志文章,评审相关文献
BMC BIOLOGY文献大全abstract:BACKGROUND:Vertebrates are characterized by possession of hypobranchial muscles (HBMs). Cyclostomes, or modern jawless vertebrates, possess a rudimentary and superficial HBM lateral to the pharynx, whereas the HBM in jawed vertebrates is internalized and anteroposteriorly specified. Precursor cells of the HBM, marked b...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/s12915-020-00851-y
更新日期:2020-09-09 00:00:00
abstract:BACKGROUND:Phylostratigraphy is a method used to correlate the evolutionary origin of founder genes (that is, functional founder protein domains) of gene families with particular macroevolutionary transitions. It is based on a model of genome evolution that suggests that the origin of complex phenotypic innovations wil...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/1741-7007-8-66
更新日期:2010-05-21 00:00:00
abstract::In the ubiquitin-proteasome system, a subset of ubiquitylated proteins requires the AAA+ ATPase p97 (also known as VCP or Cdc48) for extraction from membranes or protein complexes before delivery to the proteasome for degradation. Diverse ubiquitin adapters are known to link p97 to its client proteins, but two recent ...
journal_title:BMC biology
pub_type: 社论
doi:10.1186/1741-7007-10-48
更新日期:2012-06-13 00:00:00
abstract:BACKGROUND:Although native to North America, the invasion of the aphid-like grape phylloxera Daktulosphaira vitifoliae across the globe altered the course of grape cultivation. For the past 150 years, viticulture relied on grafting-resistant North American Vitis species as rootstocks, thereby limiting genetic stocks to...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/s12915-020-00820-5
更新日期:2020-07-23 00:00:00
abstract::Animal domestication has fascinated biologists since Charles Darwin first drew the parallel between evolution via natural selection and human-mediated breeding of livestock and companion animals. In this review we show how studies of ancient DNA from domestic animals and their wild progenitors and congeners have shed ...
journal_title:BMC biology
pub_type: 杂志文章,评审
doi:10.1186/s12915-019-0724-7
更新日期:2019-12-02 00:00:00
abstract:BACKGROUND:Microarray analysis and 454 cDNA sequencing were used to investigate a centuries-old problem in regenerative biology: the basis of nerve-dependent limb regeneration in salamanders. Innervated (NR) and denervated (DL) forelimbs of Mexican axolotls were amputated and transcripts were sampled after 0, 5, and 14...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/1741-7007-7-1
更新日期:2009-01-13 00:00:00
abstract:BACKGROUND:Polycomb-group genes (PcG) encode proteins that maintain homeotic (Hox) gene repression throughout development. Conversely, trithorax-group (trxG) genes encode positive factors required for maintenance of long term Hox gene activation. Both kinds of factors bind chromatin regions called maintenance elements ...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/1741-7007-4-9
更新日期:2006-04-14 00:00:00
abstract::The five most pervasive anthropogenic threats to biodiversity are over-exploitation, habitat changes, climate change, invasive species, and pollution. Since all of these threats can affect intraspecific biodiversity-including genetic variation within populations-humans have the potential to induce contemporary microev...
journal_title:BMC biology
pub_type: 杂志文章,评审
doi:10.1186/s12915-017-0476-1
更新日期:2018-01-15 00:00:00
abstract:BACKGROUND:The green algae Chlamydomonas reinhardtii and Volvox carteri are important models for studying light perception and response, expressing many different photoreceptors. More than 10 opsins were reported in C. reinhardtii, yet only two-the channelrhodopsins-were functionally characterized. Characterization of ...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/s12915-018-0613-5
更新日期:2018-12-06 00:00:00
abstract:BACKGROUND:The availability of abundant sequence data from key model organisms has made large scale studies of molecular evolution an exciting possibility. Here we use full length cDNA alignments comprising more than 700,000 nucleotides from human, mouse, pig and the Japanese pufferfish Fugu rubrices in order to invest...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/1741-7007-3-2
更新日期:2005-01-28 00:00:00
abstract::Few would argue that science is better done in silos, with no transparency or sharing of methods and resources. Yet scientists and scientific stakeholders (e.g., academic institutions, funding agencies, journals) alike continue to find themselves at a relative impasse in the implementation of open science practices, s...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/s12915-019-0647-3
更新日期:2019-03-27 00:00:00
abstract:BACKGROUND:Dinoflagellates are taxonomically diverse and ecologically important phytoplankton that are ubiquitously present in marine and freshwater environments. Mostly photosynthetic, dinoflagellates provide the basis of aquatic primary production; most taxa are free-living, while some can form symbiotic and parasiti...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/s12915-020-00782-8
更新日期:2020-05-24 00:00:00
abstract::Mitochondria are highly dynamic and structurally complex organelles that provide multiple essential metabolic functions. Mitochondrial dysfunction is associated with neurodegenerative conditions such as Parkinson's disease, as well as bacterial infection. Here, we explore the roles of mitochondrial autophagy (mitophag...
journal_title:BMC biology
pub_type: 杂志文章,评审
doi:10.1186/s12915-015-0129-1
更新日期:2015-04-03 00:00:00
abstract:BACKGROUND:A genome-wide association study (GWAS) is the foremost strategy used for finding genes that control human diseases and agriculturally important traits, but it often reports false positives. In contrast, its complementary method, linkage analysis, provides direct genetic confirmation, but with limited resolut...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/s12915-015-0187-4
更新日期:2015-09-21 00:00:00
abstract:BACKGROUND:A dearth of laboratory tests to study actual human approach-avoidance behavior has complicated translational research on anxiety. The elevated plus-maze (EPM) is the gold standard to assess approach-avoidance behavior in rodents. METHODS:Here, we translated the EPM to humans using mixed reality through a co...
journal_title:BMC biology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12915-017-0463-6
更新日期:2017-12-21 00:00:00
abstract:BACKGROUND:Archaeological studies have revealed a series of cultural changes around the Last Glacial Maximum in East Asia; whether these changes left any signatures in the gene pool of East Asians remains poorly indicated. To achieve deeper insights into the demographic history of modern humans in East Asia around the ...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/1741-7007-9-2
更新日期:2011-01-10 00:00:00
abstract:BACKGROUND:The internal organization of cells depends on mechanisms to ensure that transport carriers, such as vesicles, fuse only with the correct destination organelle. Several types of proteins have been proposed to confer specificity to this process, and we have recently shown that a set of coiled-coil proteins on ...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/s12915-016-0345-3
更新日期:2017-01-26 00:00:00
abstract::The global spread of SARS-CoV-2 has shaken our health care and economic systems, prompting re-evaluation of long-held views on how best to deliver care. This is especially the case for our global diagnostic strategy. While current laboratory-based centralized RT-qPCR will continue to serve as a gold standard diagnosti...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/s12915-020-00891-4
更新日期:2020-10-28 00:00:00
abstract:BACKGROUND:Dorsal spine reduction in threespine sticklebacks (Gasterosteus aculeatus) is a classic example of recurrent skeletal evolution in nature. Sticklebacks in marine environments typically have long spines that form part of their skeletal armor. Many derived freshwater populations have evolved shorter spines. Ch...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/s12915-017-0456-5
更新日期:2017-12-07 00:00:00
abstract:BACKGROUND:Mate choice is of central importance to most animals, influencing population structure, speciation, and ultimately the survival of a species. Mating behavior of male brachionid rotifers is triggered by the product of a chemosensory gene, a glycoprotein on the body surface of females called the mate recogniti...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/1741-7007-7-60
更新日期:2009-09-09 00:00:00
abstract:BACKGROUND:Antibiotic resistance is rendering common bacterial infections untreatable. Wildlife can incorporate and disperse antibiotic-resistant bacteria in the environment, such as water systems, which in turn serve as reservoirs of resistance genes for human pathogens. Anthropogenic activity may contribute to the sp...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/s12915-019-0649-1
更新日期:2019-04-08 00:00:00
abstract:BACKGROUND:In HIV-1-infected human monocyte-derived macrophages (MDMs), virus particles assemble primarily on intracellularly sequestered plasma membrane domains termed intracellular plasma membrane-connected compartments (IPMCs). Despite their clear role in virus formation, little is known of the organization, composi...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/1741-7007-11-89
更新日期:2013-08-02 00:00:00
abstract:BACKGROUND:Many pathogens secrete toxins that target key host processes resulting in the activation of immune pathways. The secreted Pseudomonas aeruginosa toxin Exotoxin A (ToxA) disrupts intestinal protein synthesis, which triggers the induction of a subset of P. aeruginosa-response genes in the nematode Caenorhabdit...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/s12915-016-0334-6
更新日期:2016-12-07 00:00:00
abstract:BACKGROUND:How tissue and organ sizes are specified is one of the great unsolved mysteries in biology. Experiments and mathematical modeling implicate feedback control of cell lineage progression, but a broad understanding of what lineage feedback accomplishes is lacking. RESULTS:By exploring the possible effects of v...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/s12915-015-0122-8
更新日期:2015-02-19 00:00:00
abstract::A recent paper in BMC Structural Biology reports the crystal structure of human prolylcarboxypeptidase (PRCP), one of the two members of the S28 peptidase family. Comparison of the substrate-binding site of PRCP with that of its family partner, dipeptidyl dipeptidase 7 (DPP7), helps to explain the different enzymatic ...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/1741-7007-8-87
更新日期:2010-06-28 00:00:00
abstract:BACKGROUND:Many Caenorhabditis elegans mutations increase longevity and much evidence suggests that they do so at least partly via changes in metabolism. However, up until now there has been no systematic investigation of how the metabolic networks of long-lived mutants differ from those of normal worms. Metabolomic te...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/1741-7007-8-14
更新日期:2010-02-10 00:00:00
abstract::Ethylene gas is a major plant hormone that influences diverse processes in plant growth, development and stress responses throughout the plant life cycle. Responses to ethylene, such as fruit ripening, are significant to agriculture. The core molecular elements of the ethylene-signaling pathway have been uncovered, re...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/s12915-016-0230-0
更新日期:2016-01-27 00:00:00
abstract:BACKGROUND:Gene drives based on CRISPR-Cas9 technology are increasingly being considered as tools for reducing the capacity of mosquito populations to transmit malaria, and one of the most promising options is driving endonuclease genes that reduce the fertility of female mosquitoes. In particular, there is much intere...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/s12915-020-00834-z
更新日期:2020-08-11 00:00:00
abstract:BACKGROUND:Cellular functions can be regulated by cell-cell interactions that are influenced by extra-cellular, density-dependent signaling factors. Dictyostelium grow as individual cells in nutrient-rich sources, but, as nutrients become depleted, they initiate a multi-cell developmental program that is dependent upon...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/s12915-019-0714-9
更新日期:2019-12-02 00:00:00
abstract:BACKGROUND:The next big challenge in human genetics is understanding the 98% of the genome that comprises non-coding DNA. Hidden in this DNA are sequences critical for gene regulation, and new experimental strategies are needed to understand the functional role of gene-regulation sequences in health and disease. In thi...
journal_title:BMC biology
pub_type: 杂志文章
doi:10.1186/1741-7007-11-106
更新日期:2013-10-14 00:00:00