Molecular insight into human platelet antigens: structural and evolutionary conservation analyses offer new perspective to immunogenic disorders.

abstract：BACKGROUND:Although the need for whole blood is declining, so too are the number of first-time and repeat blood donors. To develop new recruitment and retention strategies, therefore, we need to draw on as wide a variation in blood donor motivations as possible. The primary aim of this study is to draw on a large surve...

journal_title：Transfusion

authors： Ferguson E,Hill A,Lam M,Reynolds C,Davison K,Lawrence C,Brailsford SR

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Changes within the ABO system are regularly observed phenomena in allogeneic bone marrow transplantation (BMT) and peripheral blood progenitor cell transplantation (PBPCT). Major ABO mismatch can lead to different clinical problems including acute hemolysis after infusion of the allograft, delay of red blood...

journal_title：Transfusion

authors： Scholl S,Klink A,Mügge LO,Schilling K,Höffken K,Sayer HG

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Advances in our understanding of the risks associated with allogeneic blood transfusions (ABTs) and the growing number of patients who wish to avoid ABTs have led to the emergence of new treatment paradigms for "bloodless" medicine and surgery. STUDY DESIGN AND METHODS:Here, we review prior studies and summ...

journal_title：Transfusion

authors： Resar LM,Wick EC,Almasri TN,Dackiw EA,Ness PM,Frank SM

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:If anti-hepatitis B core antibody testing is not mandated blood donors with occult hepatitis B infection (OBI) may transmit hepatitis B virus (HBV) to a recipient in spite of the use of nucleic acid amplification technology (NAT) or pathogen inactivation (PI). STUDY DESIGN AND METHODS:We developed a model t...

journal_title：Transfusion

authors： Weusten J,van Drimmelen H,Vermeulen M,Lelie N

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:RBCs modified with cyanuric chloride activated methoxy-PEG (CmPEG; 5000 Da) are less immunogenic than untreated RBCs, and their use thus may reduce the risk of alloimmunization in chronically transfused patients. STUDY DESIGN AND METHODS:To further examine the potential utility of CmPEG-RBCs, the effects of...

journal_title：Transfusion

authors： Bradley AJ,Test ST,Murad KL,Mitsuyoshi J,Scott MD

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:There is growing interest in radio frequency identification (RFID) technology application for tracking blood products to achieve higher productivity and safety in the transfusion medicine supply chain. We have conducted a limited study to assess the temperature and biological effects of 13.56 MHz RF radiatio...

journal_title：Transfusion

authors： Davis R,Gottschall J,Gutierrez A,Hohberger C,Veeramani D,Holcombe J

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The performance of the recently launched Procleix Ultrio (Chiron/Gen-Probe) human immunodeficiency virus-1 (HIV-1), hepatitis C virus (HCV), and hepatitis B virus (HBV) blood screening assay was evaluated in a European multicenter study. STUDY DESIGN AND METHODS:Serial dilutions of reference materials were ...

journal_title：Transfusion

authors： Koppelman MH,Assal A,Chudy M,Torres P,de Villaescusa RG,Reesink HW,Lelie PN,Cuypers HT

更新日期：2005-08-01 00:00:00

abstract：:Two blood samples containing autoagglutinins reactive in room temperature tests using low-ionic strength salt (LISS) reagents, but not by conventional saline-albumin or enzyme tests, are reported. The anti-P specificity of both sera, when tested near or diluted in group AB serum, was evident by their failure to agglut...

journal_title：Transfusion

authors： Judd WJ,Steiner EA,Capps RD

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Fever accompanying vaso-occlusive crisis is a common presentation in patients with sickle cell disease (SCD) and carries a broad differential diagnosis. Here, we report a case of transfusion-transmitted malaria in a patient with SCD presenting with acute vaso-occlusive crisis and rapidly decompensating to mu...

journal_title：Transfusion

authors： Maier CL,Gross PJ,Dean CL,Chonat S,Ip A,McLemore M,El Rassi F,Stowell SR,Josephson CD,Fasano RM

更新日期：2018-06-01 00:00:00

abstract：:As the number of successful marrow transplants has increased, the lack of HLA-identical sibling donors for 60 to 70 percent of transplant candidates has become a serious problem. Pilot studies established that marrow transplantation between phenotypically HLA-identical, unrelated individuals can be accomplished succes...

journal_title：Transfusion

authors： Stroncek D,Bartsch G,Perkins HA,Randall BL,Hansen JA,McCullough J

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Extreme leukocytosis, generally defined as a white blood cell (WBC) count of more than 100 × 10(9) /L consisting largely of blast cells, especially when accompanied by clinical signs and symptoms of leukostasis or hyperviscosity, often predicts a poor clinical outcome in patients with acute leukemia. In this...

journal_title：Transfusion

authors： Kurnaz F,Sivgin S,Pala C,Yildirim R,Baldane S,Kaynar L,Solmaz M,Ozturk A,Eser B,Cetin M,Unal A

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Maternal D alloimmunization detected in early gestation requires aggressive intervention to prevent severe fetal anemia. An intrauterine transfusion (IUT) is indicated to prevent fetal death once severe fetal anemia has been detected, but is not without risk. Protocols combining therapeutic plasma exchange (...

journal_title：Transfusion

authors： Bellone M,Boctor FN

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:The prevalence of hepatitis G virus (HGV) and its strain variant, the GB agent (GBV-C) is high in non-virus-inactivated plasma products, but, persistent infection in recipients is relatively low. STUDY DESIGN AND METHODS:Stored samples from transfusion donors and recipients in a prospective study of posttra...

journal_title：Transfusion

authors： Wang JT,Chen PJ,Liu DP,Sheu JC,Wang TH,Chen DS

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Very preterm newborns receive up to three to five red blood cell (RBC) transfusions, often early, after birth. Despite awareness of the association of transfusion with increases in cytokines and markers of endothelial activation, research has focused on single transfusions weeks after birth. With pathophysio...

journal_title：Transfusion

authors： Crawford TM,Andersen CC,Stark MJ

更新日期：2020-07-25 00:00:00

abstract：BACKGROUND:Bacterial contamination or platelet (PLT) metabolism can change the pH of stored PLT concentrates (PCs). Measurement of pH for quality control is currently done on a limited basis. An easy noninvasive method was developed to obtain sequential pH measurements over time, without risking contamination and/or co...

journal_title：Transfusion

authors： Barker LM,Nanassy OZ,Reed MW,Geelhood SJ,Pfalzgraf RD,Cangelosi GA,De Korte D

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Using umbilical cord blood (UCB) cells, it was demonstrated that three virulent isolates, two highly transmissible clinical isolates and the virulent laboratory strain, demonstrated rapid growth in the UCB cells, which was significantly faster than the growth rate observed for a unique isolate. There was als...

journal_title：Transfusion

authors： Theus JW,Justus RS,Theus SA

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:The capability of holding whole blood (WB) units at ambient temperature, overnight, should help in platelet (PLT) concentrate preparation logistics. We summarize the results of a study conducted in the early 1990s that compared, in particular, PLT and red blood cell (RBC) in vivo viability properties followi...

journal_title：Transfusion

authors： Moroff G,AuBuchon JP,Pickard C,Whitley PH,Heaton WA,Holme S

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Studies have shown that packed blood cells (PBCs) stored in AS-1 (Adsol, Baxter) and AS-3 (Nutricel, Medsep Corp.) accumulate proinflammatory substances, which may contribute to increased complications from allogeneic blood transfusion. This study assessed whether supernates from PBCs stored in AS-5 (Optisol...

journal_title：Transfusion

authors： McFaul SJ,Corley JB,Mester CW,Nath J

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:The need for blood products is constant and unremitting, yet only a small percentage of eligible individuals answer the appeal to donate. Further, most new donors never return to provide a repeat donation. The ongoing need to attract and retain new donors has led to the examination of psychosocial factors th...

journal_title：Transfusion

authors： France JL,France CR,Himawan LK

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Dendritic cells (DCs) are the most potent antigen-presenting cells that initiate and regulate immune responses. They are unique in their feature to produce bioactive interleukin (IL)-12, a major proinflammatory cytokine connecting innate and adaptive immunity. Platelets (PLTs) are highly reactive components ...

journal_title：Transfusion

authors： Kissel K,Berber S,Nockher A,Santoso S,Bein G,Hackstein H

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Historically, paid blood donors were found to transmit hepatitis at higher rates than volunteers. In those older studies, paid donors frequently were recruited from prisons or slum areas--a finding consistent with the belief that monetary payment in itself did not necessarily lead to the high-risk status of ...

journal_title：Transfusion

authors： Strauss RG,Ludwig GA,Smith MV,Villhauer PJ,Randels MJ,Smith-Floss A,Koerner TA

更新日期：1994-02-01 00:00:00

abstract：:An example of anti-Cob which caused an acute hemolytic transfusion reaction is reported. Immunohematologic studies showed this antibody to be an IgG immunoglobulin that weakly bound complement and reacted in the antiglobulin phase of the crossmatch. The unit of whole blood implicated in the hemolytic transfusion react...

journal_title：Transfusion

authors： Lee EL,Bennett C

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:The clinical significance of alloimmunization to RBC antigens in sickle cell patients was analyzed by a retrospective review of the records of pediatric and adult sickle cell patients who received transfusions and who were followed over a 10-year period. STUDY DESIGN AND METHODS:Charts of pediatric and adul...

journal_title：Transfusion

authors： Aygun B,Padmanabhan S,Paley C,Chandrasekaran V

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Unexpected neonatal alloimmune thrombocytopenia (NAIT) may have devastating consequences and its management is challenging. To design future trials, evidence from the literature and existing best practice need review. STUDY DESIGN AND METHODS:This study was a cross-sectional survey of neonatal units in Germ...

journal_title：Transfusion

authors： Bassler D,Greinacher A,Okascharoen C,Klenner A,Ditomasso J,Kiefel V,Chan A,Paes B

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Invariant natural killer T cells (iNKT cells) may suppress graft-versus-host disease (GVHD) after allogeneic transplantation. The purpose of this study was to investigate the therapeutic potential of iNKT cells from major histocompatibility complex (MHC)-mismatched donors for preventing GVHD after allogeneic...

journal_title：Transfusion

authors： Yang J,Gao L,Liu Y,Ren Y,Xie R,Fan H,Qian K

更新日期：2010-02-01 00:00:00

abstract：:The possible beneficial role of white cells (WBCs) in donor blood has been investigated with respect to their capacity to remove bacteria. Preparations of buffy coat and whole blood, containing as well as reduced of WBCs, were inoculated with Staphylococcus epidermidis, S. aureus, Escherichia coli, Pseudomonas aerugin...

journal_title：Transfusion

authors： Högman CF,Gong J,Eriksson L,Hambraeus A,Johansson CS

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Blood group A and B antigens are expressed only weakly on platelets (PLTs) of most individuals but are very strongly expressed on PLTs from approximately 1 percent of normal subjects (Type II high expressers). The implications of this trait for transfusion medicine are undefined. STUDY DESIGN AND METHODS:A ...

journal_title：Transfusion

authors： Curtis BR,Fick A,Lochowicz AJ,McFarland JG,Ball RH,Peterson J,Aster RH

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Hemorrhage is the leading cause of death on the battlefield. Damage control resuscitation guidelines in the US military recommend whole blood as the preferred resuscitation product. The Armed Services Blood Program (ASBP) has initiated low-titer group O whole blood (LTOWB) production and predeployment donor ...

journal_title：Transfusion

authors： Taylor AL,Corley JB,Swingholm MT,Sloan MA,McDonald H Jr,Quesada JF,Evans CL,Ceballos WA

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Hemolysis at the time of graft infusion is one of the immediate complications in major ABO-incompatible allogeneic hematopoietic stem cell transplants (HSCTs). We conducted a retrospective analysis to evaluate the efficacy of donor-type fresh frozen plasma (FFP) in reducing isohemagglutinin titer and prevent...

journal_title：Transfusion

authors： Quek J,Lee JJ,Lim FL,Diong C,Goh YT,Gopalakrishnan S,Ho A,Hwang W,Koh M,Loh Y,Linn YC

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Life-threatening situations requiring blood transfusion under extreme conditions or in remote and austere locations, such as the battlefield or in traffic accidents, would benefit from reliable blood typing practices that are easily understood by a nonscientist or nonlaboratory technician and provide quick r...

journal_title：Transfusion

authors： Clavier B,Pouget T,Sailliol A

更新日期：2018-02-01 00:00:00