Abstract:
:This work examines the impact of the SARS-CoV2 epidemic and the organizational recommendations that have been issued since March 16 on tumor boards (TB) activity. The tumor board activity was measured from tumor board sheets extracted from the oncologic electronic file between January 7, 2019 and April 24, 2020. The pre-containment activity was compared to the activity of the containment periods but also to the equivalent periods in 2019. The number of meetings held, the average number of files reviewed per meeting including first presentations and the average number of physicians' attendance were the evaluation criteria. The study covered 191 TB that held 3943 multidisciplinary team meetings (MTM) and reviewed 72,070 files (including 30,127 first submissions). There was a moderate decrease of 8 % in the number of meetings after March 16, 2020. The number of files examined decreased by 23 % in the following month and even more by 33 % in the third period. The physicians' number who attended MTM also decreased by 25 %. The negative impact was higher in the Mediterranean part of the region. This first study of tumor board activity, covering a large region but little affected by the pandemic, shows that its impact on the participation to the MTM has been moderate. In addition, tumor boards have followed the recommendations for optimizing quorum. However, the decrease in average MTM activity, particularly for first submissions, suggests a potential delay in patient management. Complementary qualitative and quantitative works are warranted to estimate the real impact on carcinologic outcomes.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Grosclaude P,Azria D,Guimbaud R,Thibault S,Daubisse-Marliac L,Cartron G,Renaudie MJ,Dalbies PA,Delord JP,Bauvin Edoi
10.1016/j.bulcan.2020.05.001subject
Has Abstractpub_date
2020-01-01 00:00:00pages
730-737issue
7-8eissn
0007-4551issn
1769-6917pii
S0007-4551(20)30233-2journal_volume
107pub_type
杂志文章abstract::Bladder tumours are frequent with around 10,000 new cases each year in France. Less than 500 of these cases are not transitional cell carcinoma, the most frequent pathological aspect. The identification of these pathological patterns requires an initial biopsy through transurethral resection. Sarcomatoid, squamous and...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2010.1097
更新日期:2010-01-01 00:00:00
abstract::Intraportal continuous infusion of 5-FU (600 mg/m2/24 h during 7 days) was administered in the immediate postoperative course of 6 consecutive patients with colorectal metastases resected for cure (one segmentectomy and 5 nonanatomical local resections). One month later, a systemic continuous infusion of 5-FU was deli...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Conservative management of at least a part of one ovary and the uterus, in order to preserve fertility-potential, could be propose in most of patients with nonepithelial and borderline ovarian tumor. This conservative management could be performed even in patients with borderline ovarian tumor associated with noninvas...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2002-12-01 00:00:00
abstract::Leiomyosarcoma of the larynx is extremely rare, only 21 cases were reported in the literature. The authors report a personal case in a 26 years old patient treated by a total laryngectomy and analyse all cases of the literature. It comes in relative young man (42 years old) in regard to the others ORL localisations. T...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1996-10-01 00:00:00
abstract::The endothelins (ET1, ET2, ET3) are a family of peptides that exert vasoactive and mitogenic effects. ETs bind to at least two subtypes of receptors: the ETA subtype is ET1 selective whereas the ETB subtype binds ET1, ET2 and ET3. By RT-PCR, we detected ETA receptor mRNA and ETB receptor mRNA in leiomyoma and in homol...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract::In recent years, Internet has become an indispensable tool for all types of information. Its importance has increased in medicine and particularly in human malignancies. The data issued by the Internet are many and varied sources ranging from official websites to patient's blogs. HIV infection is an infection highly p...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2010.1160
更新日期:2010-10-01 00:00:00
abstract::A suspension of CE "44" embryoïd-bodies obtained from a transplanted OTT 60-50 subline was injected into the abdominal cavity of syngeneic L 129 mice. Terato-carcinoma and ascitic fluid were produced the latter containing embryoïds. In situ examinations were made by serial transverse sectioning of the entire abdomen. ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00
abstract::The 4 year results of a prospective clinical trial on the treatment of operable breast cancer, comparing the effects of preoperative radiotherapy followed by surgery with those of surgery followed or not by postoperative radiotherapy are presented for patient groups of approximately 100 each. At 4 years 85 per cent su...
journal_title:Bulletin du cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1977-01-01 00:00:00
abstract::Hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) is now an entire part of treatment of peritoneal dissemination of colorectal malignancy, and it's possible to hope prolonged survival. This treatment is more and more codified. Four indications are recognized by some tree national evaluation committees: ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2008.0553
更新日期:2008-01-01 00:00:00
abstract::In recent studies, the economic criteria has begun to be integrated to the appraisal in cancerology. The question asked by the economist can be framed as follows: what incremental cost should the collectivity or the health insurance system consent, in order to improve the care of cancer patients? This involves first t...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1997-05-01 00:00:00
abstract::Metastases are responsible for the majority of deaths from solid cancers. Metastatic phenomenon, complex, is a multi-step process where interactions between cells and with the microenvironment are essential. The organ tropism, that is the propensity of a cancer to metastasize to specific organs, can be explained by se...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2014.1889
更新日期:2014-02-01 00:00:00
abstract::The authors report on a case of a woman with acute lymphoblastic leukemia treated with cortisone therapy during pregnancy. No problems were encountered during the gestational period or at parturition; and no maternal or neonatal complications were observed. ...
journal_title:Bulletin du cancer
pub_type: 信件
doi:
更新日期:1992-01-01 00:00:00
abstract::The schooling of young people with cancer poses various problems, similar to those experienced by disabled or chronically ill children. Published data on this subject in the medical literature comes mainly from studies carried out in the USA and the UK. Cancer and its treatment can cause both direct (learning difficul...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2007-04-01 00:00:00
abstract::Results from case-control studies and prospective studies suggest that diet is involved in the causation of large bowel cancer either as initiator, promoter or inhibitor of carcinogenesis. Available data are not sufficient to serve as a basis for firm specific dietary advice. In the present situation it is attractive ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract::The Li-Fraumeni syndrome is an autosomal dominant syndrome representing a genetic predisposition to a wide spectrum of tumours including sarcomas, breast carcinomas, brain tumors and adrenocortical carcinomas. In most of the cases, tumours will develop in children and young adults. Germline mutations of the tumor supp...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1997-07-01 00:00:00
abstract::Chemotherapy-induced peripheral neuropathy (CIPN) is common with specific semiological characteristics. When CIPN appears, there are many difficulties in guaranteeing sustained treatment, especially with optimal protocol. Moreover, CIPN have bad repercussions on quality of life after cancer disease. In this article, w...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2018.07.009
更新日期:2018-11-01 00:00:00
abstract::The study of cases treated between 1970 and 1984 at the Institut Curie, in women aged 40 years and under, was undertaken in order to determine the influence of age on prognosis. The incidence of these cases was stable throughout the 15 years study period as was the very high incidence of earlier cases: 84.5%. Earlier ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Endometrial cancer is a common cancer in older women and is often associated with comorbidities. Management of metastatic disease and/or relapse requires a multidisciplinary approach. Recent advances in the understanding of oncogenesis and molecular classification of endometrial cancers offer new therapeutic perspecti...
journal_title:Bulletin du cancer
pub_type: 杂志文章,实务指引
doi:10.1016/j.bulcan.2020.06.006
更新日期:2020-10-01 00:00:00
abstract::Pain is frequent in the course of cancer and can have negative consequences on patients quality of life. The great majority of patients can be helped by simple treatments. The prescription of morphine (M) must be preceded by some explanations. In order to verify the reality of these explanations, a study was done in a...
journal_title:Bulletin du cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1998-04-01 00:00:00
abstract:INTRODUCTION:An increasing number of patients with prostate cancer (PC) are diagnosed and treated. The aim of this study was to investigate urinary incontinence (UI) and sexual dysfunction (SD) two years after treatment for localized prostate cancer (PC). METHODS:This study followed all cases of localized PC diagnosed...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2016.09.011
更新日期:2016-10-01 00:00:00
abstract:UNLABELLED:The legislative process of the surrogate appears to be unclear to health professionals and to patients and next of kin. To better adapt this process to the clinical practice our objective was here to document how the persons designated as surrogate perceived their role and how they described the difficulties...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2016.03.003
更新日期:2016-07-01 00:00:00
abstract::Antineoplastic drug induced nausea and vomiting are common adverse events in cancer care of paediatric patients ; therefore, prevention and management of these adverse events is a major concern for healthcare professionals. There are common features between paediatric and adult patients in terms of the emetogenic leve...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2020.03.015
更新日期:2020-01-01 00:00:00
abstract::The retrospective evaluation of the dose after an irradiation accident is of paramount importance; it allows an adequate selection of patients and the most appropriate treatment can then be proposed. Classical physical dosimetry often lacks precision for dose assessment in such accidents. Cytogenetics, usually more re...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:PURPOSE:GemOx was defined as a D1-D2 schedule, based on preclinical data. In order to improve convenience for patients, we evaluated a simplified D1-D1 GemOx regimen (S-GemOx) in MPA. PATIENTS AND METHODS:Patients (pts) with MPA were 2:1 randomly assigned for first-line treatment to S-GemOx (gemcitabine 1,000 mg/m(2),...
journal_title:Bulletin du cancer
pub_type: 杂志文章,随机对照试验
doi:10.1684/bdc.2009.0871
更新日期:2009-05-01 00:00:00
abstract::Estrogen receptor determinations were performed on 241 cytosols from 160 breast cancer tumors, using both dextran coated charcoal method (D.C.C.) and monoclonal antibodies (Abbott's ER-EIA kit) in order to compare the two methods, and to evaluate the clinical usefulness of this new immunological simplified assay. Intr...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::Sequencing the human genome brings new tools for the individualisation of cancer chemotherapy, especially thanks to the identification of polymorphisms of genes involved in anticancer drug metabolism or activity (pharmacogenetics). A few functional polymorphisms have been known for a long time (thiopurine methyltransf...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2008.0722
更新日期:2008-10-01 00:00:00
abstract::The tolerance and the clinical and histological efficacy of a neoadjuvant chemotherapy FEC-HD including hematopoietic growth factors have been studied in 40 patients with stade II or III breast cancer between February 1991 and February 1997. Four courses were given, every 21 days, with 5-fluorouracil (750 mg/m2/day D1...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1999-02-01 00:00:00
abstract:INTRODUCTION:Systematic metastasis staging in early breast cancer is no longer recommended. However, it is still performed before adjuvant chemotherapy. MATERIALS AND METHODS:We assessed metastasis screening of asymptomatic women with a local breast cancer without lymph node involvement when adjuvant chemotherapy was ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2015.02.018
更新日期:2015-05-01 00:00:00
abstract::Cancerogenesis is believed to be a multistep process composed of different alterations that drive the transformation of normal human cells into highly malignant derivatives. These changes include self-sufficiency in growth signals, insensitivity to growth-inhibitory signals, the evasion of programmed cell death, a lim...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2008.0600
更新日期:2008-03-01 00:00:00
abstract:INTRODUCTION:Oral anticancer drugs have raised the question of how to follow-up these patients and how to coordinate this follow-up. The CHIMORAL study evaluated the involvement of primary care providers and a coordination by territorial health networks. Training/information tools were provided, as well as weekly nursi...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2020.08.014
更新日期:2020-12-01 00:00:00