Abstract:
:The schooling of young people with cancer poses various problems, similar to those experienced by disabled or chronically ill children. Published data on this subject in the medical literature comes mainly from studies carried out in the USA and the UK. Cancer and its treatment can cause both direct (learning difficulties or other disabilities...) and indirect (discrimination...) problems. Academic failure, and other problems linked to school absenteeism, can affect the future of adolescents with cancer. Sustaining schooling during the illness enables such patients to avoid falling behind academically, and to maintain his or her social status as a student. Due to the organisation of treatment regimes, education is provided in three environments : in hospital (during in-patient stays), at home (generally whilst the patient is convalescing), or at school. Paediatric oncologists have underlined the importance of establishing links between hospital and educational personnel (with parental approval), and suggest that a teachers'illness information manual should be produced. School re-entry is recommended as soon as possible. During the illness, the patient's presence in class is dependent on his or her general health, the progress of the cancer, and the treatment regime being followed. School absenteeism, inevitable during treatment periods and the year following diagnosis, is often associated with academic problems or failure. While many cancer patients worry about their school work and future educational progress, such problems remain rare. In the long term, the educational level of childhood or adolescent cancer survivors remains similar to that of the general population. In order to understand the issues surrounding the schooling of young cancer patients in France, long-term multi-centre studies, focusing on adolescents, must be initiated.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Vignes C,Godeau E,Bertozzi-Salamon AI,Vignes M,Grandjean H,Arnaud Csubject
Has Abstractpub_date
2007-04-01 00:00:00pages
371-80issue
4eissn
0007-4551issn
1769-6917journal_volume
94pub_type
杂志文章,评审abstract::Blood glucose levels were temporarily elevated in normal and in tumor bearing Lewis rats subjected to one local hyperthermic treatment in the leg or in the upper abdomen. Serum transferred from locally heated animals or serum heated in-vitro and injected to normal recipients resulted in elevated blood glucose levels. ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::Death still occurs in Hodgkin's disease (HD) patients with advanced stages, but also in early stages. Therefore, the identification of the population of HD patients who would best benefit from an intensification of treatment is a prerequisite in all stages. The best known prognostic factors are bulky mediastinum, B sy...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1995-08-01 00:00:00
abstract::ANTI-PD-1 ANTIBODIES THERAPEUTIC USE IN LYMPHOID NEOPLASMS: Immune checkpoints blockade is under investigation in oncology, and has demonstrated its clinical efficacy. In hematology, immune checkpoints blockade is in earlier stages of development, but there are strong evidences of PD-1 blockade anti-tumor efficacy in ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/S0007-4551(16)30374-5
更新日期:2016-11-01 00:00:00
abstract::The evidence that C cell hyperplasia is the precursor of medullary carcinoma in families where this tumour is inherited is very strong. It is suggested that the tumour is the result of at least two mutations, in the families with medullary carcinoma the first of these is genetically determined, and the second is an ac...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Multidrug resistant (MDR) phenotype is characterized by a defect in drug accumulation caused by overexpression of a transmembrane glycoprotein, the P-glycoprotein (P-gp). MDR phenotype can be characterized either with monoclonal antibodies raised against P-gp or with functional tests, most often based on the incorpora...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract:INTRODUCTION:The treatment of chronic myeloid leukemia (CML) has been revolutionized by the advent of tyrosine kinase inhibitors. The results of the IRIS trial demonstrated the efficacy and long-term safety profile of Imatinib. The objective of our work is to report the results at 15 years of treatment of CML in chroni...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2020.05.013
更新日期:2020-09-01 00:00:00
abstract::The aims of this study was to estimate and describe the reasons of use of complementary medicine in patients with a cancer treated in a French oncology department. An anonymous questionnaire was proposed to patients during treatment or follow-up in an oncology department. It was a descriptive study over 207 questionna...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2007-11-01 00:00:00
abstract::Chemoprevention is the use of natural or synthetic compounds in order to reverse, suppress or prevent the carcinogenic process. Among the many pathways dysregulated during the carcinogenic process, cyclooxygenase-2 (Cox2) seems to be one of the most promising pathways to target in order to achieve chemopreventive and ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2004-05-01 00:00:00
abstract:INTRODUCTION:The diagnosis of chronic myeloid leukemia is based on the presence of translocation t(9,22). Additional cytogenetic abnormalities may exist at diagnosis and have prognostic value. The authors evaluated the relationship between these additional chromosomal abnormalities, clinical presentation, and therapeut...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2019.03.013
更新日期:2019-06-01 00:00:00
abstract::In Europe, renal tumours are 7th in frequency of men cancers. They are rare tumours in 10 to 15% of cases. Collecting ducts carcinomas or Bellini tumours, described for the first time in 1949, are a distinct clinical and pathological entity. They represented 1% of epithelial cancers. Nephrectomy is the treatment of lo...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2011.1462
更新日期:2011-10-01 00:00:00
abstract::The majority of patients with breast cancer can be treated by partial mastectomy and radiation therapy. The choice of the treatment involves the estimation of the risk for intramammary recurrence and the ability to achieve satisfactory cosmetic result. Patient selection in breast conserving therapy is dependent on cli...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1998-09-01 00:00:00
abstract::The endothelins (ET1, ET2, ET3) are a family of peptides that exert vasoactive and mitogenic effects. ETs bind to at least two subtypes of receptors: the ETA subtype is ET1 selective whereas the ETB subtype binds ET1, ET2 and ET3. By RT-PCR, we detected ETA receptor mRNA and ETB receptor mRNA in leiomyoma and in homol...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract::Sentinel lymph node (SLN) biopsy is fast becoming the standard for testing lymph node involvement in many institutions. However questions remain as to stage underestimation. The aim of this study was to analyse this specific risk in a retrospective study. Between 1975 to 1999, 1,636 patients underwent a breast cancer ...
journal_title:Bulletin du cancer
pub_type: 临床试验,杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract::Many efforts have been devoted to the development of gene therapy for primary liver tumors. This has been hampered by the absence of efficient gene transfer vectors for delivering genes into hepatoma cells in vivo. Also it remains to determine which type of gene has to be used to achieve complete tumor regression. Rec...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1997-04-01 00:00:00
abstract::We describe the psychological reactions after diagnosis and treatment of the malignant intraocular tumors: uveal melanoma and retinoblastoma. The chapter on uveal melanoma includes general consideration on the treatment of these tumors, the psychological effects on the patients, the professional and social problems, t...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2001-11-01 00:00:00
abstract::Over the last decade, the development of new therapeutic options has made more patients benefit from antitumoral strategies including several lines of chemotherapy, the aim of which is a long-term control of the disease progression. In such a context of "chronic" management, the choice of tumor response as a single pa...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2008.0738
更新日期:2008-11-01 00:00:00
abstract::Cells in spleens from tumor bearing animals were found to inhibit in vitro reactivity of lymphocytes to a variety of stimulants. These suppressor cells inhibited the stimulation of normal lymphocytes by mitogens : P.H.A.-Con A-L.P.S. They were adherent cells, bore immunoglobulins at their surface and did not bear the ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1976-04-01 00:00:00
abstract::The great majority of breast cancer cases are not associated with a mutated gene of high penetrance such as BRCA1, BRCA2 and TP53. Genes of low penetrance, frequently mutated in the general population, might play an important role in breast cancer development. The ATM gene, which encodes the ATM protein, mutated in th...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2001-07-01 00:00:00
abstract::Brain metastases management is still controversial even though many trials are trying to define the respective roles of neurosurgery, whole-brain radiotherapy, single-dose stereotactic radiotherapy and fractionated stereotactic radiotherapy. In this article, we review data from trials that examine the role of radiosur...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2012.1683
更新日期:2013-01-01 00:00:00
abstract::As compared to conventional axillary dissection, the sentinel node technique is accompanied by reduced morbidity and shorter hospital stay. Based on available data, the use of this technique does not seem to yield higher rates of axillary recurrence. A combination of both radioisotope detection and blue dye increases ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2009.0879
更新日期:2009-06-01 00:00:00
abstract::Interleukin 6 (IL-6) is a pleiotropic cytokine which possesses a broad spectrum of action in diverse pathological conditions. It is mainly produced and metabolised in the liver where it carries out one of its best known actions in the mediation of the acute phase response. We studied its behaviour in hepatocellular ca...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1996-05-01 00:00:00
abstract::Developing a secondary non Hodgkin's lymphoma (NHL) more than 12 months after treatment for first cancer, is uncommon. Secondary NHL occurs sometimes after chronic lymphatic leukemia or Hodgkin's disease. The 20 years cumulative incidence rate is 3-5% after Hodgkin's disease. Secondary NHL seems less frequent after an...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1998-03-01 00:00:00
abstract:INTRODUCTION:Breast cancer of young women has medico-psychological issues, particularly in the perspective of "after cancer" period. The objective of the study was to analyze the changes in management, in a decade including the publication of Cancer Plans I and II. METHODS:This retrospective unicentric study involved ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/S0007-4551(20)30049-7
更新日期:2019-12-01 00:00:00
abstract::During the past two years, new molecular targets have been discovered which link cell cycle, cell proliferation and cellular growth. It has become more and more evident that whereas gain-of-function mutations in specific genes can lead to cancer, genomic instability plays also an important role in tumour progression. ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2002-01-01 00:00:00
abstract::Estrogen receptors (ER) were investigated using immunohistochemical techniques in 54 cases and biochemical techniques in 38 cases on a series of biopsy specimens of normal, hyperplasic and malignant mammary tissue (intraductal carcinoma). Immunohistochemical data were submitted to quantitative and semi-quantitative an...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::In man, the period of maximum risk for the embryo and foetus is between the second and tenth week after conception. The most frequent and most severe malformation is microcephaly which in extreme cases is accompanied by mental retardation. The results of studies in experimental animals and man agree that it is impossi...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract:INTRODUCTION:Adolescents and young adults (AYA, 15-25years old) with cancer are treated either in adult or pediatric units. Management of febrile neutropenia (FN) is different between these units. Monitoring rules and indications of hospitalization are often stricter in pediatrics. This study evaluates if these differe...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2015.08.001
更新日期:2015-11-01 00:00:00
abstract::CD44 gene products are potential markers of aggressiveness in different tumor models, a result which prompted us to study clinical neuroblastoma (NB) specimens. CD44 expression was determined by immunostaining of 52 NB with a monoclonal antibody (J173) directed against an epitope common to all CD44 isoforms. All tumor...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Neuroblastoma is the most common pediatric extracranial solid cancer. Patients with metastatic disease at initial diagnosis who are greater than 18 months of age and patients with MycN amplified locoregional tumors are treated with intensive multimodal therapy. While this intensive approach has been shown to improve ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2011.1353
更新日期:2011-05-01 00:00:00
abstract::Receptor assays for both ER and PR in breast cancer specimens is used either to choose adjuvant therapy during the first treatment, or to choose hormone therapy for metastatic patients, or for the diagnosis of tumors. Whereas biochemical methods, either by radioligand or by monoclonal antibodies, have progressed over ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00