[Value of detection of hormone receptors by biochemical and immunochemical methods in therapeutic decision for breast cancer].

Abstract:

:Receptor assays for both ER and PR in breast cancer specimens is used either to choose adjuvant therapy during the first treatment, or to choose hormone therapy for metastatic patients, or for the diagnosis of tumors. Whereas biochemical methods, either by radioligand or by monoclonal antibodies, have progressed over the last 20 years, other methods such as immunohistochemistry are used now for receptor detection, and bring new data useful for patient therapy. This paper summarizes the qualities and pitfalls of these different methods, and shows that the use of data from both biochemical and histochemical methods can help the physician in therapeutic decisions.

journal_name

Bull Cancer

journal_title

Bulletin du cancer

authors

Goussard J

subject

Has Abstract

pub_date

1996-12-01 00:00:00

pages

1031-6

issue

12

eissn

0007-4551

issn

1769-6917

journal_volume

83

pub_type

杂志文章
  • [Asbestos and malignant pleural mesothelioma: molecular, cellular and physiopathological aspects].

    abstract::Asbestos is known as mutagenic and carcinogenic for human and is responsible for many pulmonary diseases including asbestosis, bronchogenic carcinoma and malignant pleural mesothelioma. Occupational exposure to asbestos is involved in 70-80% of all malignant pleural mesothelioma. The later presents a growing challenge...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Mohr S,Keith G,Rihn B

    更新日期:2005-11-01 00:00:00

  • [CD44 expression: a new prognostic factor in neuroblastoma].

    abstract::CD44 gene products are potential markers of aggressiveness in different tumor models, a result which prompted us to study clinical neuroblastoma (NB) specimens. CD44 expression was determined by immunostaining of 52 NB with a monoclonal antibody (J173) directed against an epitope common to all CD44 isoforms. All tumor...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Combaret V,Lasset C,Bouvier R,Frappaz D,Thiesse P,Rebillard AC,Philip T,Favrot MC

    更新日期:1995-01-01 00:00:00

  • [Surgery after chemotherapy: gastric cancer].

    abstract::Perioperative chemotherapy for gastric cancer is validated by two phase III studies. The impact of the preoperative neoadjuvant sequence is probably major in the benefit of this treatment. This chemotherapy increases the R0 resection without increasing either morbidity or mortality. Furthermore, it reduces local and s...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2010.1287

    authors: Flamein R,Antomarchi O,Pezet D

    更新日期:2011-01-01 00:00:00

  • [Primary prevention of colorectal cancer].

    abstract::Results from case-control studies and prospective studies suggest that diet is involved in the causation of large bowel cancer either as initiator, promoter or inhibitor of carcinogenesis. Available data are not sufficient to serve as a basis for firm specific dietary advice. In the present situation it is attractive ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Faivre J,Couillault C,Belghiti C

    更新日期:1995-07-01 00:00:00

  • Putative role of antioxidant enzymes and glyoxalases in carcinogenesis.

    abstract::The effects various drugs exert on antioxidant enzyme and glyoxalase activity in rat livers were studied. All drugs tested provoked a marked reduction in glutathione peroxidase and a small drop in both glyoxalase I and II activity. It is hypothesized that the substances tested support tumour development by neutralizin...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Liotti FS,Menghini AR,Guerrieri P,Mariucci G,Armellini R

    更新日期:1993-01-01 00:00:00

  • [Intra-operative radiation therapy in tumors of the digestive tract].

    abstract::All the retrospective and prospective studies concerning IORT in tumors of the digestive tract tend to substantiate a significant improvement in local control without a significant increase in survival. Improvements in the results of IORT can be expected in the near future, and may occur on several fronts: - Technolog...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Dubois JB

    更新日期:2001-02-01 00:00:00

  • [Proton therapy in soft tissue and bone sarcomas].

    abstract::Sarcomas are a common type of tumor within the pediatric population. The utilization of proton therapy as a primary attribute the ability to spare adjacent healthy tissue, therefore, proton therapy has become a preferential indication in pediatrics compared to other photon irradiation modalities. Proton therapy is als...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1016/j.bulcan.2018.05.008

    authors: Thariat J,Tessonnier T,Bonvalot S,Lerouge D,Mammar H,Bolle S,Claren A,Duffaud F,Alapetite C,Vogin G

    更新日期:2018-09-01 00:00:00

  • [Prognostic factors in multiple myeloma. Review of the literature].

    abstract::Apparition of new tools in the therapy of multiple (MM) strengthens the need for valuable prognostic categorization of each patient in order to propose the most adequate treatment. Prognostic factors in MM can be divided in four groups. The first, including beta 2 microglobulin (beta 2m), hemopoiesis impairment, osteo...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Bauduer F,Troussard X,Delmer A

    更新日期:1993-12-01 00:00:00

  • [Place of autologous and allogeneic hematopoietic stem cell transplantation in ovarian cancer].

    abstract::For several years, research for treatment of advanced ovarian cancer in first line or in relapse was made on the basis of two concepts. The first one is to improve the response rate by increasing the dose of chemotherapy delivered by high dose chemotherapy consolidation. The second concept is the development of an imm...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2009.1004

    authors: Nayl B,Cabrespine-Faugeras A,Maliki Y,Bay JO

    更新日期:2009-12-01 00:00:00

  • [MDR (Multiple Drug Resistant) type of resistance to chemotherapy in clinical practice].

    abstract::Multifactorial resistance is the main mechanism of chemotherapy failure in cancers. Multidrug resistance (MDR) is related to the expression of a 170 kDa membrane glycoprotein, the so-called P-glycoprotein (P-gp). This protein is able to extrude drugs of various structures and mechanisms out of the cytoplasm. P-gp is a...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Oudard S,Marie JP,Pujade Lauraine E

    更新日期:1996-08-01 00:00:00

  • [Urinary incontinence and sexual dysfunction after treatment of localized prostate cancer: Results from a population aged less than 65years old].

    abstract:INTRODUCTION:An increasing number of patients with prostate cancer (PC) are diagnosed and treated. The aim of this study was to investigate urinary incontinence (UI) and sexual dysfunction (SD) two years after treatment for localized prostate cancer (PC). METHODS:This study followed all cases of localized PC diagnosed...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1016/j.bulcan.2016.09.011

    authors: Bessaoud F,Orsini M,Iborra F,Rebillard X,Faix A,Soulier M,Daurès JP,Trétarre B

    更新日期:2016-10-01 00:00:00

  • [Checkpoint inhibitors-induced hypophysitis].

    abstract::Checkpoint inhibitors immunotherapy is more and more prescribed in oncology, causing new immune related endocrine adverse events. Hypophysitis occurs in approximately 10 % of patients treated with anti-CTLA4. It occurs two to three months after initiation of the immunotherapy. The initial presentation is characterized...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1016/j.bulcan.2020.01.012

    authors: du Payrat JA,Cugnet-Anceau C,Maillet D,Levy M,Raverot G,Disse E,Borson-Chazot F

    更新日期:2020-04-01 00:00:00

  • [Ultrastructural study of 36 lymph node sites of Hodgkin's disease].

    abstract::The authors report their ultrastructural findings of 36 involved lymph-nodes in Hodgkin's disease (HD), before any treatment. More than 400 tumour cells were studied. An analytical study was carried out on the different aspects presented by the nuclei (uni or multi-lobated); the nucleoli (compact, reticulate or disper...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Diebold J,Reynes M,Marchal G,Tricottet V,Mrena E

    更新日期:1986-01-01 00:00:00

  • [What can be now expected of the determination of estrogen and progesterone receptors in the treatment of breast cancers].

    abstract::Since the first published correlations around the years 1975 between estrogen and progesterone receptors and response to hormone therapy, numerous data have modified our insight on hormone dependency. For instance, it is now well established that tumors are not "receptor positive" or "receptor negative" but contain va...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Goussard J,Génot JY

    更新日期:1994-01-01 00:00:00

  • [Prospective evaluation of pain induced by the transport of patients in the hospital: risk factors and proposal for improvement].

    abstract::Cancer patients are often moved inside the hospital to different examination clinics, such as radiology, CT scan, MRI... and to treatment clinics, such as radiotherapy. These transports induce important pain phenomena, not really recognized by professional teams. As these kinds of pains are expected and can be prevent...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1684/bdc.2008.0638

    authors: Nebbak JM,Mathivon D,Di Palma M

    更新日期:2008-05-01 00:00:00

  • [Angiogenesis targeting in renal carcinomas].

    abstract::Angiogenesis targeting with inhibitors of VEGF receptors is currently modifying in depth the treatment strategy of metastatic clear cell renal carcinoma. Although immunotherapy remains prescribed in selected patients with good prognosis, sunitinib and sorafenib are presently the most active agents in this malignancy. ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Pouessel D,Culine S

    更新日期:2007-01-01 00:00:00

  • [Fertility and the progeny of children surviving cancer treatment (author's transl)].

    abstract::Little is known about the late effects of damage to the gonads in children treated for cancer. This investigation requires a prolonged surveillance. Radiotherapy sterilizes the ovaries above a dose of about 500 rads in an adult. Therefore, to protect at least one ovary in partial irradiation of a child's abdomen in ma...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Flamant F,Schweisguth O

    更新日期:1979-01-01 00:00:00

  • [New molecular classification of colorectal cancer, pancreatic cancer and stomach cancer: Towards "à la carte" treatment?].

    abstract::This review reports 3 of recently published molecular classifications of the 3 main gastro-intestinal cancers: gastric, pancreatic and colorectal adenocarcinoma. In colorectal adenocarcinoma, 6 independent classifications were combined to finally hold 4 molecular sub-groups, Consensus Molecular Subtypes (CMS 1-4), lin...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1016/j.bulcan.2016.05.007

    authors: Dreyer C,Afchain P,Trouilloud I,André T

    更新日期:2016-07-01 00:00:00

  • [Cancer of the uterine cervix in young women. A retrospective study of 337 cases].

    abstract::A retrospective study of 337 cases of cervix cancers in women aged 35 years and under, treated between 1980-1990 at the Ibn Rochd Oncology Center in Casablanca, was analyzed in order to determine the main characteristics of this disease and the influence of age on prognosis. The incidence of these cases was stable thr...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Acharki A,Sahraoui S,Benider A,Tawfiq N,Jouhadi H,Bouras N,Samlali R,Kahlain A

    更新日期:1997-04-01 00:00:00

  • [Radiotherapy for sarcoma: hadrontherapy, for whom and what for?].

    abstract::The radiobiological properties of the hadrons (neutrons, protons, carbon ions) led to their therapeutic use in sarcomas, as a referent therapy or as an alternative to photon therapy. An extensive review of the literature has been conducted to assess the present indications and the perspectives for hadrontherapy. Compa...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2010.1125

    authors: Pommier P,Sunyach MP,Hu Y,Amsalem E,Claude L,Moncort-Boulch D,Toutenu P,Balosso J

    更新日期:2010-06-01 00:00:00

  • Loss of efficacy of ondansetron-dexamethasone during successive courses in female patients receiving high-dose cisplatin.

    abstract::This study was designed to evaluate the efficiency of the association ondansetron-dexamethasone during successive courses in 22 chemotherapy-naive female patients receiving a chemotherapy regimen including cisplatin at a dose of 100 mg/m2. The antiemetic treatment consisted of dexamethasone 20 mg i.v. and ondansetron ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Chevalier-Evain V,Bonneterre J,Adenis A,Pion JM,Hecquet B

    更新日期:1994-03-01 00:00:00

  • A phase II trial of early intensive chemotherapy with autologous bone marrow transplantation in the treatment of poor prognosis non seminomatous germ cell tumors.

    abstract::Twenty-eight patients with poor prognosis, advanced metastatic non seminomatous germ cell tumors (NSGCT) were treated with early high dose chemotherapy and autologous bone marrow transplantation (ABMT) rescue. The primary tumor was testicular in 19 patients and extragonadal in nine patients. For 19 patients with a tes...

    journal_title:Bulletin du cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Droz JP,Pico JL,Ghosn M,Kramar A,Rey A,Ostronoff M,Baume D

    更新日期:1992-01-01 00:00:00

  • [Cyclooxygenase 2 inhibitors and cancer chemoprevention].

    abstract::Chemoprevention is the use of natural or synthetic compounds in order to reverse, suppress or prevent the carcinogenic process. Among the many pathways dysregulated during the carcinogenic process, cyclooxygenase-2 (Cox2) seems to be one of the most promising pathways to target in order to achieve chemopreventive and ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Masmoudi A,Chevalier TL,Sabatier L,Soria JC

    更新日期:2004-05-01 00:00:00

  • [Stereotactic radiosurgery and radiotherapy for brain metastases].

    abstract::Brain metastases management is still controversial even though many trials are trying to define the respective roles of neurosurgery, whole-brain radiotherapy, single-dose stereotactic radiotherapy and fractionated stereotactic radiotherapy. In this article, we review data from trials that examine the role of radiosur...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2012.1683

    authors: Tanguy R,Métellus P,Mornex F,Mazeron JJ

    更新日期:2013-01-01 00:00:00

  • [Not Available].

    abstract:SURGICAL DE-ESCALATION FOR INVASIVE BREAST CANCER TREATMENT:A surgical therapeutic de-escalation is going to continue but necessarily has to design in a progressive careful way and especially arranged with the other practitioners and therapeutic methods. These strategies concern as well the surgery of the breast as tha...

    journal_title:Bulletin du cancer

    pub_type: 社论

    doi:10.1016/S0007-4551(16)30151-5

    authors: Houvenaeghel G,Cohen M,Bannier M,Jauffret C,Buttarelli M,Lambaudie E

    更新日期:2016-06-01 00:00:00

  • [Withholding and withdrawal decisions in oncology: legal frame and practice].

    abstract::Whereas medicine is progressing in illness treatment that used to be incurable, physicians are still faced with treatment failure. Hippocrates used to say: "primum non nocere" [1]. When the patient cannot expect benefit from potentially aggressive care, current or possible treatments have to be challenged to leave jus...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1684/bdc.2009.0910

    authors: Laude C,Deygas S

    更新日期:2009-07-01 00:00:00

  • [Image guided radiation therapy (IGRT)].

    abstract::Image guided radiation therapy (IGRT) is a major technical innovation of radiotherapy. It allows locating the tumor under the linear accelerator just before the irradiation, by direct visualization (3D mode soft tissue) or indirect visualization (2D mode and radio-opaque markers). The technical implementation of IGRT ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1684/bdc.2010.1140

    authors: Lagrange JL,de Crevoisier R

    更新日期:2010-07-01 00:00:00

  • [Symptomatic management of brain metastasis].

    abstract::Indications and choice of antiepileptic drugs (AED), treatments for cerebral edema and prophylactic and curative treatments of thromboembolic complications of brain metastasis are discussed. ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2012.1689

    authors: Le Rhun E,Taillandier L,Beauchene P,Bailon O,Dubois F

    更新日期:2013-01-01 00:00:00

  • [The detection of sentinel lymph node in nuclear medicine].

    abstract::The isotopic detection of the sentinel node is undergoing a fast development in breast cancer and melanoma. It requires a good collaboration between a surgeon and a nuclear medicine specialist. Although the method is now well defined for melanoma, several options remain possible for breast cancer. The injected dose an...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Maublant J,Cachin F,Mesta D,Geissler B

    更新日期:2002-07-01 00:00:00

  • Bilateral adrenal metastases of renal cell carcinoma: a case report.

    abstract::We report a case of renal cell carcinoma presenting with bilateral adrenal masses diagnosed by ultrasonography four years after nephrectomy. The histopathological examination of the trucut biopsy specimens obtained percutaneously by ultrasound guidance revealed bilateral adrenal mestastases of renal cell carcinoma. ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Sahin A,Ozen H,Ozmen M,Remzi D

    更新日期:1994-02-01 00:00:00