Abstract:
RATIONALE FOR SYSTEMATIC REVIEW:Lassa fever is the most common cause of imported haemorrhagic fevers cases in non-endemic countries. As a disease with a high case fatality rate that has regularly caused clusters of nosocomial transmission in endemic areas, prompt diagnosis is vital. We conducted a systematic review of imported cases of the last 50 years with the aim of defining the clinical and epidemiological characteristics that will enhance early diagnosis, prompt initiation of treatment and an appropriate public health response to Lassa fever cases. METHODS:We performed a retrospective, systematic review of 36 primary and two secondary cases of Lassa fever in non-endemic countries outside West Africa by searching the PubMed database. This yielded 56 relevant publications that were included in our analysis. RESULTS:The case fatality rate of 35.1% for imported cases was higher than that reported for endemic countries. The majority of patients showed clinical features consistent with Lassa fever and had a typical exposure. There was a considerable delay in diagnosis in imported cases with high associated numbers of contacts. Ribavirin was rarely used for post-exposure prophylaxis. Only two secondary transmissions occurred. Thirty-one percent of patients received Lassa fever-specific treatment and five required intensive care. CONCLUSIONS:Although importation of Lassa fever to non-endemic countries is a rare event, it has repeatedly happened over five decades. Suspicion of Lassa fever should be based on careful consideration of clinical features and exposure history in order to assist early diagnosis in returning travellers from West Africa.
journal_name
J Travel Medjournal_title
Journal of travel medicineauthors
Wolf T,Ellwanger R,Goetsch U,Wetzstein N,Gottschalk Rdoi
10.1093/jtm/taaa035subject
Has Abstractpub_date
2020-07-14 00:00:00issue
4eissn
1195-1982issn
1708-8305pii
5808990journal_volume
27pub_type
杂志文章abstract::Nine imported Zika virus (ZIKV) infections (four through temperature monitoring and epidemiological investigation at entry and five by active surveillance tracking of index case contacts during follow-up; from Venezuela [n = 5], Samoa [n = 3] and both Samoa and Fiji [n = 1]) were detected in mainland China from Februa...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1093/jtm/taw047
更新日期:2016-07-04 00:00:00
abstract::Two Japanese travelers from Bali were diagnosed with murine typhus in Japan during the same period. Although one had only mild illness, the other experienced liver and kidney dysfunction. Murine typhus may be missed not only in endemic areas around the world, but also in travelers, especially those returning from mari...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2010.00438.x
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Sexual behavior during travel has increasingly become a focus of travel medicine research. The perceived freedom when away from home can lead to increased casual sexual activities, often unprotected. Local sexual partners, particularly those who are in close contact with tourists due to their occupation, nee...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2007.00110.x
更新日期:2007-05-01 00:00:00
abstract::Travel medicine has virtually stopped in light of the coronavirus pandemic. It is worth contemplating how travel medicine will be affected by the ongoing pandemic when international travel starts to become more possible. How will we advise patients, and utilize the coming vaccines that may be available? Travel medicin...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1093/jtm/taaa148
更新日期:2020-08-28 00:00:00
abstract::In recent years, several studies have shown that Cyclospora cayetanensis is a worldwide intestinal pathogen, and it has been implicated in a number of sporadic cases and epidemic outbreaks of diarrheal illness in several endemic areas. The parasite is associated with prolonged and relapsing watery diarrhea in immunoco...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2004.13640
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Internet travel purchases accounted for 10% of the travel industry revenue generated in 2001. To ensure that travelers remain healthy during excursions to developing countries, travel health information needs to be available at commercial travel websites. We evaluated the current availability of travel healt...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2003.2699
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:Millions of Americans visit developing countries each year, however, little is known about their health during travel. This study describes health problems in a large cohort of American travelers during and after their trip. METHODS:A 2-year survey of 784 travelers (95% follow-up) was conducted for persons ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2000.00075
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Medical emergencies often occur on commercial airline flights, but valid data on their causes and consequences are rare. Therefore, it is unclear what emergency medical equipment is necessary. Although a minimum standard for medical equipment is defined in regulations, additional material is not standardized...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/jtm.12138
更新日期:2014-09-01 00:00:00
abstract::Acute eosinophilic pneumonia (AEP) has been reported following chloroquine or mefloquine exposure, both structurally related to piperaquine. We report a case of AEP with typical CT scan patterns, hypereosinophilia in blood (9.8 109/l), and bronchoalveolar lavage (78% of 600 000 cells/ml), 10 days after artenimol-piper...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1093/jtm/tax023
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Neurocysticercosis (NCC) is an important cause of adult-onset seizures in endemic areas, whereas it is emerging in some nonendemic areas as well because of extensive immigration. METHOD:We describe three cases of imported NCC recently admitted to San Bortolo Hospital in Vicenza, located in Northern Italy. ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/jtm.12066
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Prior to initiation of a program of registration, training, standards, and audit for yellow fever vaccination centers (YFVCs) in England, the National Travel Health Network and Centre (NaTHNaC) assessed the current practice and resource needs of these centers. METHODS:A questionnaire was sent to all YFVCs o...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2008.00217.x
更新日期:2008-09-01 00:00:00
abstract::A 35-year-old healthy Dutch woman went on a trek (Lang Tang) in Nepal up to an approximate altitude of about 3800 meters. She had no prior history of any medical problems except attacks of generalized epilepsy when she was 19 years old, which had been controlled with antiepileptic medications. She had had no attacks a...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.1998.tb00512.x
更新日期:1998-12-01 00:00:00
abstract::A 34-year-old patient presented with giant, transient urticarial skin lesions and periorbital edema after a 3-month stay in DR Congo. Retrospective analysis of stored samples revealed that these signs were prodromal manifestations of acute hepatitis B infection. The hepatitis B infection was spontaneously cleared; the...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2011.00507.x
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Young people's alcohol and drug use increases during holidays. Despite strong associations between substance use and both violence and unintentional injury, little is known about this relationship in young people holidaying abroad. We examine how risks of violence and unintentional injury abroad relate to su...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2010.00489.x
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:Scarce data are available on the occurrence of ailments and diseases in children during travel. We studied the characteristics and frequencies of ailments in children aged 0 to 18 years and their parents during traveling. METHODS:A prospective observational study on ailments reported by children and parents ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2011.00551.x
更新日期:2012-05-01 00:00:00
abstract:Background:While the worldwide endemicity of tick-borne encephalitis (TBE) has been increasing, a lack of awareness of the risks of this life-threatening disease may be leading to an underutilization of preventive measures among travellers to TBE-endemic regions. This study's objectives were to assess travellers' aware...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1093/jtm/tay063
更新日期:2019-02-01 00:00:00
abstract::We report the case of an Anthia sexmaculata sexmaculata-associated necrotic burn in a French expatriate in Mauritania. Anthia spp.-related injury is a common though underreported health issue in the Sahelo-Saharan area. Deployed soldiers and travellers should be aware of these beetles when adventuring in this region. ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1093/jtm/tay033
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The number of international trips undertaken by residents of the United Kingdom has risen dramatically over the past 50 years. Likewise, the numbers studying in higher education have also shown a huge increase. This study aimed to assess the appropriateness of advice given to traveling students by higher edu...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2004.19202
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:Thirteen clustered cases of American histoplasmosis, a deep mycosis caused by Histoplasma capsulatum and acquired through inhalation of airborne spores was reported. Twenty-five persons traveled in Martinique, French West Indies. Thirteen underwent trekking and passed through a mountain tunnel full of bats (...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2003.31755
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Schistosoma haematobium and Schistosoma mansoni are endemic to East Africa. US Peace Corps volunteers (PCVs) serving in Tanzania were not experiencing symptoms of infection, but in 1998 when comprehensive testing was instituted, more than one-quarter were found to be infected with schistosomiasis at the clos...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2005.12505
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:Following the severe acute respiratory syndrome (SARS) outbreak, remote-sensing infrared thermography (IRT) has been advocated as a possible means of screening for fever in travelers at airports and border crossings, but its applicability has not been established. We therefore set out to evaluate (1) the fea...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2004.19102
更新日期:2004-09-01 00:00:00
abstract::In a marine envenomation, identification of the culprit organism can be difficult. In this case report, we present our method to identify snakelocks anemone (Anemonia viridis or formerly Anemonia sulcata) as the culprit of a severe toxic skin reaction. A. viridis is one of the most common anemones of the Mediterranean...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/jtm.12223
更新日期:2015-07-01 00:00:00
abstract::We describe a case of trichinellosis diagnosed at the Division of Infectious Diseases, Hospital of Lugano, in January 2009. This case was associated with a cluster of cases and was traced to the consumption of contaminated meat after a wild boar hunt in Bosnia. ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2012.00603.x
更新日期:2012-05-01 00:00:00
abstract::Vaccination against yellow fever is effective, but available live virus vaccines are not recommended for use in immunocompromised or elderly patients. We report the successful and uneventful immunization of a 62-year-old man with a history of allogeneic bone marrow transplant and discuss evidence for this recommendati...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2009.00336.x
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Adventure travel necessarily places travelers at risk of environmental hazards. We assessed the burden of "environmental" hazards among a cohort of travelers and expatriates presenting to a large travel clinic in Nepal. METHODS:Data on travelers and expatriates seen at the Canadian International Water and E...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2007.00145.x
更新日期:2007-11-01 00:00:00
abstract::Scrub typhus should be considered in any febrile patient presenting with a macular rash, a polyadenopathy, an eschar, or a history of environmental exposure in endemic areas. The differential diagnosis includes malaria, typhoid fever, leptospirosis, and arboviroses. Doxycycline 100 mg twice daily for 7 days should be ...
journal_title:Journal of travel medicine
pub_type: 杂志文章,评审
doi:10.1111/j.1708-8305.2007.00151.x
更新日期:2007-09-01 00:00:00
abstract:BACKGROUND:Conventional treatment of imported malaria in Italy consists of quinine or mefloquine. Since beta-arthemeter is now available, an open-label pharmacodynamic analysis was performed in 73 adults with uncomplicated Plasmodium falciparum malaria. In vitro susceptibility to mefloquine and quinine was evaluated at...
journal_title:Journal of travel medicine
pub_type: 临床试验,杂志文章
doi:10.2310/7060.2005.12305
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:Several live attenuated vaccines against bacterial enteric pathogens have recently been licensed. These include the Salmonella typhi Ty21a typhoid vaccine (Vivotif Berna(R) Vaccine) and Vibrio cholerae CVD103-HgR cholera vaccine (Mutacol Berna(R) Vaccine). They comprise a unique class of biologics in which p...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.1998.tb00449.x
更新日期:1998-03-01 00:00:00
abstract:BACKGROUND:The prevalence of motion sickness approaches 100% on rough seas. Some previous studies have reported a strong association between location on a ship and the risk of motion sickness, whereas other studies found no association. This study was undertaken to determine if there is a statistical association betwee...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2000.00042
更新日期:2000-05-01 00:00:00
abstract::We report two cases of symptomatic neurocysticercosis in two migrants whose negative serology delayed appropriate treatment for 9 and 6 months, respectively. Seroconversion occurred after treatment, which was associated with paradoxical reaction in one patient. Long-term outcome was good in both patients. ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2012.00658.x
更新日期:2012-12-01 00:00:00