Abstract:
:A 35-year-old healthy Dutch woman went on a trek (Lang Tang) in Nepal up to an approximate altitude of about 3800 meters. She had no prior history of any medical problems except attacks of generalized epilepsy when she was 19 years old, which had been controlled with antiepileptic medications. She had had no attacks after the age of 20. A CT scan done around that time had apparently been normal. On this trek she had developed diarrhea which had been cured with norfloxacin 400 mg two times per day for 3 days. Two days later, while descending, she developed a grand mal seizure at an altitude of 3300 meters, after which she developed a classic postictal phase but gradually recovered. She developed grand mal seizures again the next day, but when she went to a travel clinic in Kathmandu, she had been seizure free for 72 hours. She also revealed that she had not suffered from acute mountain sickness on the trek. She also had a prior history of gastroenteritis at high altitude which improved significantly with norfloxacin, a quinolone antibiotic. This was corroborated by her party. Upon examination she was fully conscious and oriented to person, place and time. Her pulse was 70 beats per minute and her BP was 110/80 mm of Hg. Her fundi and cranial nerves exam were completely normal. Her abstract thinking, gait, power, tone, reflexes and other facets of her neurologic exam revealed absolutely no abnormalities. Her cardiovascular exam revealed a normal rhythm with no murmurs or bruits. The rest of her exam was also normal. She revealed that she played tennis on a regular basis and was an outdoor person. She had not trekked before in the Himalayas and it was uncertain if she had been to high altitude before. She was on no medications at the time. There was no history of drug abuse. She did not smoke and consumed few alcoholic beverages. She had not consumed any alcohol on the trek. She was advised to get a CT scan (she declined as she was going home to Holland in 2 days) and she was prescribed a loading dose of phenytoin 1 g orally spread over several hours and it was recommended she take 300 mg of phenytoin per day. She was going to see her neurologist in Holland on arrival there. She went to her hotel in Kathmandu while her friends went to fill the prescription of phenytoin. When her friends returned to the hotel she was having another grand mal seizure. Medical help was sought, but she died before the doctor arrived to control her seizures. When the doctor did arrive and carried out CPR for half an hour it was to no avail as she continued to have no pulse or blood pressure.
journal_name
J Travel Medjournal_title
Journal of travel medicineauthors
Basnyat Bdoi
10.1111/j.1708-8305.1998.tb00512.xsubject
Has Abstractpub_date
1998-12-01 00:00:00pages
221-2issue
4eissn
1195-1982issn
1708-8305journal_volume
5pub_type
杂志文章abstract:BACKGROUND:Millions of Americans visit developing countries each year, however, little is known about their health during travel. This study describes health problems in a large cohort of American travelers during and after their trip. METHODS:A 2-year survey of 784 travelers (95% follow-up) was conducted for persons ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2000.00075
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:This experiment was carried out to determine whether there is any difference in circulating rabies antibody when rabies immune globulin is administered into fat or muscle tissue. METHODS:Blood samples were taken at 24 and 48 hours after administering 40 IU/kg body weight of purified equine rabies immune glo...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2000.00057
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:Dengue has emerged as a frequent problem in international travelers. The risk depends on destination, duration, and season of travel. However, data to quantify the true risk for travelers to acquire dengue are lacking. METHODS:We used mathematical models to estimate the risk of nonimmune persons to acquire ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2009.00310.x
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Sexual behavior during travel has increasingly become a focus of travel medicine research. The perceived freedom when away from home can lead to increased casual sexual activities, often unprotected. Local sexual partners, particularly those who are in close contact with tourists due to their occupation, nee...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2007.00110.x
更新日期:2007-05-01 00:00:00
abstract::Acute eosinophilic pneumonia (AEP) has been reported following chloroquine or mefloquine exposure, both structurally related to piperaquine. We report a case of AEP with typical CT scan patterns, hypereosinophilia in blood (9.8 109/l), and bronchoalveolar lavage (78% of 600 000 cells/ml), 10 days after artenimol-piper...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1093/jtm/tax023
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:In February 2012, crew and passengers of a cruise ship sailing off the coast of São Paulo, Brazil, were hospitalized for acute respiratory illness (ARI). A field investigation was performed to identify the disease involved and factors associated. METHODS:Information on passengers and crew with ARI was obtai...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/jtm.12132
更新日期:2014-09-01 00:00:00
abstract::Mass gathering is well known to concentrate and amplify the transmission of infectious respiratory diseases. Here we report a possible case of coinfection with influenza A/H1N1 and varicella in a young French traveler returning from a rock festival in Hungary. We report a cluster of influenza A/H1N1 cases at this fest...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2010.00410.x
更新日期:2010-05-01 00:00:00
abstract::Scrub typhus should be considered in any febrile patient presenting with a macular rash, a polyadenopathy, an eschar, or a history of environmental exposure in endemic areas. The differential diagnosis includes malaria, typhoid fever, leptospirosis, and arboviroses. Doxycycline 100 mg twice daily for 7 days should be ...
journal_title:Journal of travel medicine
pub_type: 杂志文章,评审
doi:10.1111/j.1708-8305.2007.00151.x
更新日期:2007-09-01 00:00:00
abstract::A putative underdiagnosis of clinical chikungunya virus infection in Dutch travelers to the Indian Ocean area was addressed by retrospective screening of all sera for which requested dengue virus serology was negative in the period 2007 to 2010. Evidence for a recent infection was observed in 6.5% of 107 patients, ind...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2012.00670.x
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To assess the awareness of the mode of rabies transmission, travel-associated rabies risk, and adequate preventive measures among French travelers. METHODS:Three hundred travelers were administered a detailed questionnaire prior to pretravel advice, addressing their knowledge, attitudes, and practices (KAP) ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2008.00283.x
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:There is concern about the risk of yellow fever (YF) establishment in Asia, owing to rising numbers of urban outbreaks in endemic countries and globalisation. Following an outbreak in Angola in 2016, YF cases were introduced into China. Prior to this, YF had never been recorded in Asia, despite climatic suit...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1093/jtm/taab015
更新日期:2021-01-28 00:00:00
abstract::Travel medicine practitioners, perhaps more so than medical practitioners working in other areas of medicine, require a constant flow of information to stay up-to-date, and provide best practice information and care to their patients. Many travel medicine providers are unaware of the popularity and potential of the Tw...
journal_title:Journal of travel medicine
pub_type: 杂志文章,评审
doi:10.1093/jtm/taw002
更新日期:2016-03-16 00:00:00
abstract::Background: Climate change is not only increasing ambient temperature but also accelerating the frequency, duration and intensity of extreme weather and climate events, such as heavy precipitation and droughts, and causing sea level rise, which can lead to population displacement. Climate change-related reductions in ...
journal_title:Journal of travel medicine
pub_type: 杂志文章,评审
doi:10.1093/jtm/taz026
更新日期:2019-06-11 00:00:00
abstract:BACKGROUND:Acetazolamide has been reported to be effective in the prevention of acute mountain sickness (AMS). Our aim was to conduct a systematic review of randomized, placebo-controlled trials of acetazolamide in the prevention of AMS. METHODS:Studies were identified by searching the MEDLINE, Embase, Cochrane Clinic...
journal_title:Journal of travel medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1708-8305.2012.00629.x
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:In 2011, the Centers for Disease Control and Prevention and the New Jersey Department of Health used the New Jersey Behavioral Risk Factor Survey (NJBRFS), a state component of the national Behavioral Risk Factor Surveillance System (BRFSS) to pilot a travel health module designed to collect population-based...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1093/jtm/tav015
更新日期:2016-01-18 00:00:00
abstract::We report two cases of symptomatic neurocysticercosis in two migrants whose negative serology delayed appropriate treatment for 9 and 6 months, respectively. Seroconversion occurred after treatment, which was associated with paradoxical reaction in one patient. Long-term outcome was good in both patients. ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2012.00658.x
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Infectious diarrhea is a common problem among travelers. Expert guidelines recommend the prompt use of antibiotics for self-treatment of moderate or severe travelers' diarrhea (TD). There is limited data on whether travelers follow these self-treatment guidelines. We evaluated the risk factors associated wit...
journal_title:Journal of travel medicine
pub_type: 杂志文章,多中心研究
doi:10.1111/jtm.12179
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Adventure trips to Africa have become more frequent, and rafting on some of the great rivers has become almost commonplace. We describe three rafting trips on the Omo River in Ethiopia, after which most of the participants were diagnosed with schistosomiasis. METHODS:After index cases from the three groups ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2005.00002
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Pontiac fever (PF), a legionellosis with influenza-like symptoms and high attack rates, is rarely reported. Travel-related outbreaks can elude detection because infected persons are often widely removed geographically from the transmission source before illness onset. Thirty-one persons staying at an Illinoi...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2005.12401
更新日期:2005-07-01 00:00:00
abstract::A small group of travellers became infected with Echinostoma sp. after ingesting raw fish which they caught in Lake Tanganyika, Tanzania, in January 2017. The infection was diagnosed by finding the characteristic eggs in stool samples collected over a 2-week period following their return to Kenya. Echinostoma is a gen...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1093/jtm/tax036
更新日期:2017-09-01 00:00:00
abstract::A non-pregnant Canadian woman returning from India presented with a 1-week history of jaundice and malaise. Subsequently, she developed fulminant hepatic failure caused by hepatitis E virus (HEV). HEV can cause fulminant hepatic failure, most commonly in pregnant women and those with chronic liver disease; however, al...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1093/jtm/taw021
更新日期:2016-04-11 00:00:00
abstract::A case of Japanese encephalitis virus (JEV) infection is reported in a young traveler returning from Thailand. Clinical suspicion of JEV in travelers returning from endemic areas with neurologic symptoms is warranted. Confirmation of the diagnosis is complex and requires specialized laboratory services. Individualized...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2011.00582.x
更新日期:2012-03-01 00:00:00
abstract::Shigella bacteremias are uncommon in immune-competent adults. We report two cases of Shigella flexneri bacteremia that occurred in healthy young travelers, who recovered. Self-medication with loperamide and ibuprofen without antibiotics (case 1) and concomitant falciparum malaria (case 2) were the only co-morbidities ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2012.00627.x
更新日期:2012-07-01 00:00:00
abstract::Japanese encephalitis (JE) is an infection caused by a mosquito-transmitted virus present in many parts of Asia, including India, and Oceania. Infection is usually asymptomatic, leading to overt encephalitis in only 0.1-5% of infected individuals. When encephalitis occurs it is usually severe, with a 25% fatality rate...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.1997.tb00766.x
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND:International travel and use of modern information technology are expressions of modern life style. Seeking on-line travel health advice via E-mail for preventive (teleprevention) or diagnostic reasons may become increasingly popular among patients with financial resources and Internet access. This study was...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2001.24423
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:The effectiveness of preventive measures in combating travel-related illnesses is well recognized. However, there is a lack of information on the economic value of any travel-associated preventive measures in the literature. OBJECTIVES:The purpose of this article is to report the values of willingness to pa...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2005.12202
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND:Following the severe acute respiratory syndrome (SARS) outbreak, remote-sensing infrared thermography (IRT) has been advocated as a possible means of screening for fever in travelers at airports and border crossings, but its applicability has not been established. We therefore set out to evaluate (1) the fea...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2004.19102
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:Medical tourism is a growing phenomenon. This review of the literature maps current knowledge and discusses findings with reference to the UK National Health Service (NHS). METHODS:Databases were systematically searched between September 2011 and March 2012 and 100 papers were selected for review. RESULTS:...
journal_title:Journal of travel medicine
pub_type: 杂志文章,评审
doi:10.1111/jtm.12147
更新日期:2014-11-01 00:00:00
abstract:Background:Obstructive sleep apnoea syndrome is a common condition for which continuous positive airways pressure (CPAP) is the standard treatment. The condition affects a population of which a substantial proportion will be travelling. Methods:We use a questionnaire survey of CPAP users to gain understanding regardin...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1093/jtm/tax085
更新日期:2018-01-01 00:00:00
abstract::Loiasis, caused by the filarial nematode Loa loa, is often asymptomatic but frequently manifests as episodic angioedema and periocular migration of adult worms. Hence also known as the eye worm.(1) It is rarely encountered in the United States among travelers and immigrants. This report describes a case of loiasis in ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2007.00166.x
更新日期:2008-01-01 00:00:00