Effects of immunomodulating therapy in systemic sclerosis.

Abstract:

:We reviewed studies concerning immunomodulating therapy in systemic sclerosis. These comprise mostly uncontrolled trials and case reports. Some of these studies hint at a possible beneficial effect of antimetabolites (azathioprine, 5-fluoro-uracil and methotrexate), cyclosporine and interferon-gamma. However, to give a clearcut answer on the efficacy of these drugs in systemic sclerosis, controlled studies are urgently needed.

journal_name

Clin Rheumatol

journal_title

Clinical rheumatology

authors

van den Hoogen FH,Boerbooms AM,van de Putte LB

doi

10.1007/BF02114391

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

319-24

issue

3

eissn

0770-3198

issn

1434-9949

journal_volume

9

pub_type

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