当前位置： SCI文献检索 > JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY期刊下所有文献 > Severe renal impairment and stroke prevention in atrial fibrillation: implications for thromboprophylaxis and bleeding risk.

Severe renal impairment and stroke prevention in atrial fibrillation: implications for thromboprophylaxis and bleeding risk.

Abstract：

:The prevalence of atrial fibrillation (AF) in end-stage renal failure is high, with an increased risk of stroke among these patients with AF compared with the AF population without severe renal impairment. Many trials have shown the net clinical benefit of oral anticoagulation therapy for primary and secondary prevention of stroke in patient populations with AF. However, current stroke risk stratification schemes are based on studies that have deliberately excluded patients with severe renal impairment. Indeed, there are no large randomized controlled trials that assess the real risk/benefit of full intensity anticoagulation in patients with severe renal impairment. Also, rates of major bleeding episodes in anticoagulated hemodialysis patients with AF are high. These data are influenced by the lack of appropriate monitoring, the difficulties in maintaining the international normalized ratio target (variable between the studies), and an inaccurate bleeding classification. Thus, the limited available data may be difficult to apply to such a heterogeneous patient population, characterized by both an increased risk of bleeding and a hypercoagulability state, as seen in the patient population with severe renal impairment.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

Marinigh R,Lane DA,Lip GY

doi

10.1016/j.jacc.2010.12.013

subject

Has Abstract

pub_date

2011-03-22 00:00:00

pages

1339-48

issue

12

eissn

0735-1097

issn

1558-3597

pii

S0735-1097(11)00090-8

journal_volume

57

pub_type

杂志文章,评审

相关文献

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY文献大全
  • Clinical outcomes of patients with severe aortic stenosis at increased surgical risk according to treatment modality.

    abstract：OBJECTIVES:The aim of this study was to assess the role of transcatheter aortic valve implantation (TAVI) compared with medical treatment (MT) and surgical aortic valve replacement (SAVR) in patients with severe aortic stenosis (AS) at increased surgical risk. BACKGROUND:Elderly patients with comorbidities are at cons...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jacc.2011.05.063

    authors： Wenaweser P,Pilgrim T,Kadner A,Huber C,Stortecky S,Buellesfeld L,Khattab AA,Meuli F,Roth N,Eberle B,Erdös G,Brinks H,Kalesan B,Meier B,Jüni P,Carrel T,Windecker S

    更新日期：2011-11-15 00:00:00

  • Randomized trial of cardiac resynchronization in mildly symptomatic heart failure patients and in asymptomatic patients with left ventricular dysfunction and previous heart failure symptoms.

    abstract：OBJECTIVES:We sought to determine the effects of cardiac resynchronization therapy (CRT) in New York Heart Association (NYHA) functional class II heart failure (HF) and NYHA functional class I (American College of Cardiology/American Heart Association stage C) patients with previous HF symptoms. BACKGROUND:Cardiac res...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.jacc.2008.08.027

    authors： Linde C,Abraham WT,Gold MR,St John Sutton M,Ghio S,Daubert C,REVERSE (REsynchronization reVErses Remodeling in Systolic left vEntricular dysfunction) Study Group.

    更新日期：2008-12-02 00:00:00

  • Development and validation of simplified predictive index for major complications in contemporary percutaneous transluminal coronary angioplasty practice. The Registry Committee of the Society for Cardiac Angiography and Interventions.

    abstract：OBJECTIVES:This study was designed to determine the preprocedural risk factors for major complications (emergent coronary bypass surgery, myocardial infarction or death) of coronary angioplasty and to derive and validate a simplified index that predicts patients' a priori risk of complications. BACKGROUND:Previous stu...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/0735-1097(95)00294-4

    authors： Kimmel SE,Berlin JA,Strom BL,Laskey WK

    更新日期：1995-10-01 00:00:00

  • Ablation of rotor and focal sources reduces late recurrence of atrial fibrillation compared with trigger ablation alone: extended follow-up of the CONFIRM trial (Conventional Ablation for Atrial Fibrillation With or Without Focal Impulse and Rotor Modulat

    abstract：OBJECTIVES:The aim of this study was to determine if ablation that targets patient-specific atrial fibrillation (AF)-sustaining substrates (rotors or focal sources) is more durable than trigger ablation alone at preventing late AF recurrence. BACKGROUND:Late recurrence substantially limits the efficacy of pulmonary ve...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.jacc.2014.02.543

    authors： Narayan SM,Baykaner T,Clopton P,Schricker A,Lalani GG,Krummen DE,Shivkumar K,Miller JM

    更新日期：2014-05-06 00:00:00

  • Development of Quality Metrics in Ambulatory Pediatric Cardiology.

    abstract：:The American College of Cardiology Adult Congenital and Pediatric Cardiology (ACPC) Section had attempted to create quality metrics (QM) for ambulatory pediatric practice, but limited evidence made the process difficult. The ACPC sought to develop QMs for ambulatory pediatric cardiology practice. Five areas of interes...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2016.11.043

    authors： Chowdhury D,Gurvitz M,Marelli A,Anderson J,Baker-Smith C,Diab KA,Edwards TC,Hougen T,Jedeikin R,Johnson JN,Karpawich P,Lai W,Lu JC,Mitchell S,Newburger JW,Penny DJ,Portman MA,Satou G,Teitel D,Villafane J,Williams

    更新日期：2017-02-07 00:00:00

  • Relationship between renal function and plasma brain natriuretic peptide in patients with heart failure.

    abstract：OBJECTIVES:This study sought to evaluate the relationship between brain natriuretic peptide (BNP), renal function, and the severity of congestive heart failure (CHF). BACKGROUND:Both BNP and renal function are prognostic predictors in CHF patients. METHODS:We measured the plasma BNP level in the aortic root and coron...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2005.10.038

    authors： Tsutamoto T,Wada A,Sakai H,Ishikawa C,Tanaka T,Hayashi M,Fujii M,Yamamoto T,Dohke T,Ohnishi M,Takashima H,Kinoshita M,Horie M

    更新日期：2006-02-07 00:00:00

  • Nonthoracotomy internal defibrillation in dogs: threshold reduction using a subcutaneous chest wall electrode with a transvenous catheter electrode.

    abstract：:The efficacy of truncated exponential waveform shocks using a cardioverter-defibrillator catheter with and without a 13.9 cm2 subcutaneous thoracic patch electrode was examined in 10 pentobarbital-anesthetized dogs. The cardioverter-defibrillator catheter was positioned through the external jugular vein with the dista...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(87)80025-6

    authors： Wetherbee JN,Chapman PD,Klopfenstein HS,Bach SM Jr,Troup PJ

    更新日期：1987-08-01 00:00:00

  • Prognostic value of N-terminal proatrial natriuretic factor plasma levels measured within the first 12 hours after myocardial infarction. Thrombolysis in Myocardial Infarction (TIMI) II Investigators.

    abstract：OBJECTIVES:The aim of the present study was to examine the relation between the plasma levels of the atrial peptide N-terminal proatrial natriuretic factor (proANF) measured during the 1st 12 h after myocardial infarction and 1-year mortality. BACKGROUND:The atrial peptides atrial natriuretic factor and N-terminal pro...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(95)00342-8

    authors： Hall C,Cannon CP,Forman S,Braunwald E

    更新日期：1995-11-15 00:00:00

  • Thoracoscopic extracardiac obliteration of the left atrial appendage for stroke risk reduction in atrial fibrillation.

    abstract：OBJECTIVES:We evaluated left atrial appendage obliteration in high-risk patients with atrial fibrillation (AF). BACKGROUND:Left atrial appendage thrombosis and embolization is the principal mechanism of stroke in AF. Anticoagulation is underutilized and often contraindicated. METHODS:Thoracoscopic Left Appendage, Tot...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/s0735-1097(03)00953-7

    authors： Blackshear JL,Johnson WD,Odell JA,Baker VS,Howard M,Pearce L,Stone C,Packer DL,Schaff HV

    更新日期：2003-10-01 00:00:00

  • Pravastatin therapy in hyperlipidemia: effects on thrombus formation and the systemic hemostatic profile.

    abstract：OBJECTIVES:The study sought to determine the effects of lipid-lowering with pravastatin on the systemic fibrinolytic profile and on thrombus formation under dynamic flow conditions. BACKGROUND:Lowering cholesterol (C) decreases clinical events in coronary artery disease (CAD) patients, but an analysis of the effects o...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0735-1097(99)00018-2

    authors： Dangas G,Badimon JJ,Smith DA,Unger AH,Levine D,Shao JH,Meraj P,Fier C,Fallon JT,Ambrose JA

    更新日期：1999-04-01 00:00:00

  • Quality of care for atrial fibrillation among patients hospitalized for heart failure.

    abstract：OBJECTIVES:This study sought to examine quality of care and warfarin use at discharge in patients with atrial fibrillation (AF) and heart failure (HF). BACKGROUND:Atrial fibrillation is common in HF, and national guidelines recommend discharge on warfarin for stroke prophylaxis. However, the frequency and factors asso...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jacc.2009.04.091

    authors： Piccini JP,Hernandez AF,Zhao X,Patel MR,Lewis WR,Peterson ED,Fonarow GC,Get With The Guidelines Steering Committee and Hospitals.

    更新日期：2009-09-29 00:00:00

  • Prophylactic versus selective lidocaine for early ventricular arrhythmias of myocardial infarction.

    abstract：:A total of 333 patients arriving within 6 h of the onset of suspected or proven but uncomplicated myocardial infarction were randomized to treatment by either the prophylactic or the selective lidocaine strategy. Patients were monitored for 24 h. The major end points were sustained ventricular tachycardia or fibrillat...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0735-1097(88)90427-5

    authors： Wyse DG,Kellen J,Rademaker AW

    更新日期：1988-08-01 00:00:00

  • Aortic Bioprosthetic Valve Durability: Incidence, Mechanisms, Predictors, and Management of Surgical and Transcatheter Valve Degeneration.

    abstract：:In recent times, there has been a considerable increase in the use of aortic bioprostheses (vs. mechanical prostheses) for treating aortic valve disease, and this tendency is likely to continue in the near future. However, the occurrence of structural valve degeneration, limiting valve durability, remains an important...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2017.07.715

    authors： Rodriguez-Gabella T,Voisine P,Puri R,Pibarot P,Rodés-Cabau J

    更新日期：2017-08-22 00:00:00

  • Platelet glycoprotein IIb/IIIa receptor blockade and coronary resistance in unstable angina.

    abstract：OBJECTIVES:We designed a study to explore the effect of glycoprotein (GP) IIb/IIIa blockade on the atherosclerotic plaque and distal coronary vasculature. BACKGROUND:Platelet GP IIb/IIIa blockers have been proven to be beneficial in acute ischemic syndromes. This effect has also been attributed to the prevention of mi...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0735-1097(02)02590-1

    authors： Marzilli M,Sambuceti G,Testa R,Fedele S

    更新日期：2002-12-18 00:00:00

  • The early repolarization pattern in the general population: clinical correlates and heritability.

    abstract：OBJECTIVES:This study sought to describe the clinical correlates and heritability of the early repolarization pattern (ERP) in 2 large, population-based cohorts. BACKGROUND:There is growing recognition that ERP is associated with adverse outcomes. METHODS:Participants of the Framingham Heart Study (FHS) (N = 3,995) a...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2011.04.003

    authors： Noseworthy PA,Tikkanen JT,Porthan K,Oikarinen L,Pietilä A,Harald K,Peloso GM,Merchant FM,Jula A,Väänänen H,Hwang SJ,O'Donnell CJ,Salomaa V,Newton-Cheh C,Huikuri HV

    更新日期：2011-05-31 00:00:00

  • Clinical and angiographic comparison of matched patients with successful directional coronary atherectomy or stent implantation for primary coronary artery lesions.

    abstract：OBJECTIVES:This study was designed to compare the long-term clinical and angiographic effects of successful directional atherectomy and stent implantation and to examine whether restenosis is related to the mechanism of lumen improvement as well as the extent of lumen gain. BACKGROUND:Directional atherectomy and coron...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(96)00229-x

    authors： Umans VA,Melkert R,Foley DP,Serruys PW

    更新日期：1996-09-01 00:00:00

  • B-type natriuretic peptide and prognosis in heart failure patients with preserved and reduced ejection fraction.

    abstract：OBJECTIVES:This study sought to determine the prognostic value of B-type natriuretic peptide (BNP) in patients with heart failure with preserved ejection fraction (HFPEF), in comparison to data in HF patients with reduced left ventricular (LV) EF (≤40%). BACKGROUND:Management of patients with HFPEF is difficult. BNP i...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2012.12.044

    authors： van Veldhuisen DJ,Linssen GC,Jaarsma T,van Gilst WH,Hoes AW,Tijssen JG,Paulus WJ,Voors AA,Hillege HL

    更新日期：2013-04-09 00:00:00

  • Echocardiographic predictors of left ventricular outflow tract obstruction and systolic anterior motion of the mitral valve after mitral valve reconstruction for myxomatous valve disease.

    abstract：OBJECTIVE:To determine predictors of systolic anterior motion and left ventricular outflow tract obstruction (SAM/LVOTO) after mitral valve repair (MVRep) in patients with myxomatous mitral valve disease. BACKGROUND:Mechanisms for the development of SAM/LVOTO after MVRep have been described; however, predictors of thi...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(99)00464-7

    authors： Maslow AD,Regan MM,Haering JM,Johnson RG,Levine RA

    更新日期：1999-12-01 00:00:00

  • Ergonovine maleate testing during cardiac catheterization: a 10-year perspective in 3,447 patients without significant coronary artery disease or Prinzmetal's variant angina.

    abstract：:The utility of ergonovine testing for coronary artery spasm was assessed in 3,447 patients with angiographically insignificant (less than 50% diameter stenosis) or no coronary artery disease. No patients clinically had Prinzmetal's variant angina. Overall, 4% had a positive ergonovine test result, defined by spasm cau...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(92)90145-d

    authors： Harding MB,Leithe ME,Mark DB,Nelson CL,Harrison JK,Hermiller JB,Davidson CJ,Pryor DB,Bashore TM

    更新日期：1992-07-01 00:00:00

  • Effect of physician volume on the relationship between hospital volume and mortality during primary angioplasty.

    abstract：OBJECTIVES:We sought to examine the combined effect of hospital and physician volume of primary percutaneous coronary intervention (PCI) on in-hospital mortality. BACKGROUND:An inverse relationship between volume and outcome has been observed for both hospitals and physicians after primary PCI for acute myocardial inf...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2008.09.056

    authors： Srinivas VS,Hailpern SM,Koss E,Monrad ES,Alderman MH

    更新日期：2009-02-17 00:00:00

  • Percutaneous balloon angioplasty in an infant with obstructed total anomalous pulmonary vein return.

    abstract：:This is a report of successful dilation of stenosis of the common trunk in a case of total anomalous pulmonary vein return into the left superior vena cava in a 3 month old infant. Percutaneous angioplasty was performed with a 6 mm diameter balloon catheter. Right ventricular systolic pressure decreased from 96 to 60 ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(85)80501-5

    authors： Rey C,Marache P,Francart C,Dupuis C

    更新日期：1985-10-01 00:00:00

  • Estimating Longitudinal Risks and Benefits From Cardiovascular Preventive Therapies Among Medicare Patients: The Million Hearts Longitudinal ASCVD Risk Assessment Tool: A Special Report From the American Heart Association and American College of Cardiolog

    abstract：:The Million Hearts Initiative has a goal of preventing 1 million heart attacks and strokes-the leading causes of mortality-through several public health and healthcare strategies by 2017. The American Heart Association and American College of Cardiology support the program. The Cardiovascular Risk Reduction Model was ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2016.10.018

    authors： Lloyd-Jones DM,Huffman MD,Karmali KN,Sanghavi DM,Wright JS,Pelser C,Gulati M,Masoudi FA,Goff DC Jr

    更新日期：2017-03-28 00:00:00

  • Renal artery stent placement: utility in lesions difficult to treat with balloon angioplasty.

    abstract：OBJECTIVES:We assessed the safety and efficacy of stent placement in patients with poorly controlled hypertension and renal artery stenoses, which are difficult to treat with balloon angioplasty alone. BACKGROUND:Preliminary experience with stent placement suggests improved results over balloon angioplasty alone in pa...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0735-1097(97)00348-3

    authors： White CJ,Ramee SR,Collins TJ,Jenkins JS,Escobar A,Shaw D

    更新日期：1997-11-15 00:00:00

  • Lipoprotein(a) and inflammation in human coronary atheroma: association with the severity of clinical presentation.

    abstract：OBJECTIVES:The purpose of this study was the investigation of the in vivo role of lipoprotein(a) [Lp(a)] and inflammatory infiltrates in the human coronary atherosclerotic plaque and their correlation with the clinical syndrome of presentation. BACKGROUND:Lipoprotein(a) is an atherogenic and thrombogenic lipoprotein, ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(98)00469-0

    authors： Dangas G,Mehran R,Harpel PC,Sharma SK,Marcovina SM,Dube G,Ambrose JA,Fallon JT

    更新日期：1998-12-01 00:00:00

  • Surgical versus balloon therapy for aortic coarctation in infants < or = 3 months old.

    abstract：OBJECTIVES:This study compared the efficacy and safety of balloon angioplasty with surgical correction of native aortic coarctation in infants < or = 3 months old. BACKGROUND:There is a controversy with regard to the role of balloon angioplasty in the treatment of aortic coarctation, especially in young infants. METH...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(94)90395-6

    authors： Rao PS,Chopra PS,Koscik R,Smith PA,Wilson AD

    更新日期：1994-05-01 00:00:00

  • A randomized controlled trial of a paclitaxel-eluting stent versus a similar bare-metal stent in saphenous vein graft lesions the SOS (Stenting of Saphenous Vein Grafts) trial.

    abstract：OBJECTIVES:The aim of this study was to compare the frequency of angiographic restenosis and clinical events between a paclitaxel-eluting stent (PES) and a similar bare-metal stent (BMS) in saphenous vein graft (SVG) lesions. BACKGROUND:There are conflicting and mostly retrospective data on outcomes after drug-eluting...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.jacc.2008.11.029

    authors： Brilakis ES,Lichtenwalter C,de Lemos JA,Roesle M,Obel O,Haagen D,Saeed B,Gadiparthi C,Bissett JK,Sachdeva R,Voudris VV,Karyofillis P,Kar B,Rossen J,Fasseas P,Berger P,Banerjee S

    更新日期：2009-03-17 00:00:00

  • Increased Aortic Valve Calcification in Familial Hypercholesterolemia: Prevalence, Extent, and Associated Risk Factors.

    abstract：BACKGROUND:Familial hypercholesterolemia is typically caused by LDL receptor (LDLR) mutations that result in elevated levels of LDL cholesterol (LDL-C). In homozygous FH, the prevalence of aortic valve calcification (AoVC) reaches 100% and is often symptomatic. OBJECTIVES:The objective of this study was to investigate...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2015.09.087

    authors： Ten Kate GR,Bos S,Dedic A,Neefjes LA,Kurata A,Langendonk JG,Liem A,Moelker A,Krestin GP,de Feyter PJ,Roeters van Lennep JE,Nieman K,Sijbrands EJ

    更新日期：2015-12-22 00:00:00

  • Systemic and cardiac neuroendocrine activation and severity of myocardial ischemia in humans.

    abstract：OBJECTIVES:The purpose of this study was to assess the effect of different degrees of ischemia on circulating and cardiac neurohormones and vasotone. BACKGROUND:Neuroendocrine activation and subsequent systemic vasoconstriction may complicate ischemia. Whether this relates to severity of ischemia and subsequent cardia...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(94)90505-3

    authors： Remme WJ,Kruyssen DA,Look MP,Bootsma M,de Leeuw PW

    更新日期：1994-01-01 00:00:00

  • Influence of alterations in loading produced by lower body negative pressure on aortic blood flow acceleration.

    abstract：:The objectives of this study were to evaluate the effects of alterations in loading induced by lower body negative pressure on aortic blood flow velocity and acceleration. Twenty-seven normal men were studied during various levels of lower body negative pressure (0 to -60 mm Hg) during which echocardiographic, Doppler...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(90)90242-h

    authors： Berk MR,Evans J,Knapp C,Harrison MR,Kotchen T,DeMaria AN

    更新日期：1990-04-01 00:00:00

  • Predictive factors for development of the no-reflow phenomenon in patients with reperfused anterior wall acute myocardial infarction.

    abstract：OBJECTIVES:We sought to elucidate the clinical factors related to the development of no-reflow phenomenon after successful coronary reperfusion in patients with an acute myocardial infarction (AMI). BACKGROUND:Myocardial contrast echocardiography revealed that the no-reflow phenomenon is observed in some patients with...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(01)01405-x

    authors： Iwakura K,Ito H,Kawano S,Shintani Y,Yamamoto K,Kato A,Ikushima M,Tanaka K,Kitakaze M,Hori M,Higashino Y,Fujii K

    更新日期：2001-08-01 00:00:00