A randomized controlled trial of a paclitaxel-eluting stent versus a similar bare-metal stent in saphenous vein graft lesions the SOS (Stenting of Saphenous Vein Grafts) trial.

Abstract:

OBJECTIVES:The aim of this study was to compare the frequency of angiographic restenosis and clinical events between a paclitaxel-eluting stent (PES) and a similar bare-metal stent (BMS) in saphenous vein graft (SVG) lesions. BACKGROUND:There are conflicting and mostly retrospective data on outcomes after drug-eluting stent implantation in SVGs. METHODS:Patients requiring SVG lesion stenting were randomized to BMS or PES. The primary study end point was binary in-segment restenosis at 12-month follow-up quantitative coronary angiography. Secondary end points included death, myocardial infarction, ischemia-driven target vessel and lesion revascularization, and target vessel failure. RESULTS:Eighty patients with 112 lesions in 88 SVGs were randomized to a BMS (39 patients, 43 grafts, 55 lesions) or PES (41 patients, 45 grafts, 57 lesions). Binary angiographic restenosis occurred in 51% of the BMS-treated lesions versus 9% of the PES-treated lesions (relative risk: 0.18; 95% confidence interval [CI]: 0.07 to 0.48, p < 0.0001). During a median follow-up of 1.5 years the PES patients had less target lesion revascularization (28% vs. 5%, hazard ratio: 0.38; 95% CI: 0.15 to 0.74, p = 0.003) and target vessel failure (46% vs. 22%, hazard ratio: 0.65; 95% CI: 0.42 to 0.96, p = 0.03), a trend toward less target vessel revascularization (31% vs. 15%, hazard ratio: 0.66; 95% CI: 0.39 to 1.05, p = 0.08) and myocardial infarction (31% vs. 15%, hazard ratio: 0.67; 95% CI: 0.40 to 1.08, p = 0.10), and similar mortality (5% vs. 12%, hazard ratio: 1.56; 95% CI: 0.72 to 4.11, p = 0.27). CONCLUSIONS:In SVG lesions, PES are associated with lower rates of angiographic restenosis and target vessel failure than BMS.

journal_name

J Am Coll Cardiol

authors

Brilakis ES,Lichtenwalter C,de Lemos JA,Roesle M,Obel O,Haagen D,Saeed B,Gadiparthi C,Bissett JK,Sachdeva R,Voudris VV,Karyofillis P,Kar B,Rossen J,Fasseas P,Berger P,Banerjee S

doi

10.1016/j.jacc.2008.11.029

subject

Has Abstract

pub_date

2009-03-17 00:00:00

pages

919-28

issue

11

eissn

0735-1097

issn

1558-3597

pii

S0735-1097(08)03970-3

journal_volume

53

pub_type

杂志文章,多中心研究,随机对照试验
  • Clinical utility of C-reactive protein measured at admission, hospital discharge, and 1 month later to predict outcome in patients with acute coronary disease. The RISCA (recurrence and inflammation in the acute coronary syndromes) study.

    abstract:OBJECTIVES:This study was designed to prospectively determine, in patients with an acute coronary syndrome, whether the inflammatory marker, C-reactive protein (CRP), measured at hospital admission, discharge, and 1 month later has incremental value to predict outcomes at 1 year. BACKGROUND:The clinical utility of CRP...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jacc.2008.03.019

    authors: Bogaty P,Boyer L,Simard S,Dauwe F,Dupuis R,Verret B,Huynh T,Bertrand F,Dagenais GR,Brophy JM

    更新日期:2008-06-17 00:00:00

  • Interventricular mechanical asynchrony in pulmonary arterial hypertension: left-to-right delay in peak shortening is related to right ventricular overload and left ventricular underfilling.

    abstract:OBJECTIVES:The purpose of this study was to explore in pulmonary arterial hypertension (PAH) whether the cause of interventricular asynchrony lies in onset of shortening or duration of shortening. BACKGROUND:In PAH, leftward ventricular septal bowing (LVSB) is probably caused by a left-to-right (L-R) delay in myocardi...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2007.10.041

    authors: Marcus JT,Gan CT,Zwanenburg JJ,Boonstra A,Allaart CP,Götte MJ,Vonk-Noordegraaf A

    更新日期:2008-02-19 00:00:00

  • Remodeling of the aorta after successful balloon coarctation angioplasty.

    abstract::The purpose of this study was to examine whether remodeling of the aorta takes place after successful balloon angioplasty of aortic coarctation. During the 35 month period ending in December 1987, 30 children, aged 14 days to 13 years, underwent balloon angioplasty of unoperated aortic coarctation, with a resultant re...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(89)90434-8

    authors: Rao PS,Carey P

    更新日期:1989-11-01 00:00:00

  • Focal atrial tachycardia arising from the mitral annulus: electrocardiographic and electrophysiologic characterization.

    abstract:OBJECTIVES:The study was done to characterize the electrocardiographic and electrophysiologic features of focal atrial tachycardia originating at the mitral annulus (MA). BACKGROUND:Though the majority of left atrial tachycardias originate around the ostia of the pulmonary veins, only isolated reports have described f...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(03)00484-4

    authors: Kistler PM,Sanders P,Hussin A,Morton JB,Vohra JK,Sparks PB,Kalman JM

    更新日期:2003-06-18 00:00:00

  • Electromagnetic interference from welding and motors on implantable cardioverter-defibrillators as tested in the electrically hostile work site.

    abstract:OBJECTIVES:This study was designed to determine the susceptibility of an implanted cardioverter-defibrillator to electromagnetic interference in an electrically hostile work site environment, with the ultimate goal of allowing the patient to return to work. BACKGROUND:Normal operation of an implanted cardioverter-defi...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(96)00147-7

    authors: Fetter JG,Benditt DG,Stanton MS

    更新日期:1996-08-01 00:00:00

  • Characterization of the human right ventricular pressure-volume relation: effect of dobutamine and right coronary artery stenosis.

    abstract::Right ventricular function was assessed in 15 patients using right ventricular pressure-volume loops. Right ventricular pressure using a micromanometer-tipped catheter, thermodilution cardiac output and gated blood pool scintigrams were simultaneously obtained. To help isolate the right ventricle, a slant hole collima...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(84)80062-5

    authors: Friedman BJ,Lozner EC,Curfman GD,Herzberg D,Rolett EL

    更新日期:1984-11-01 00:00:00

  • Endothelial vasomotor dysfunction in the brachial artery is associated with late in-stent coronary restenosis.

    abstract:OBJECTIVES:This study examined whether endothelial dysfunction in the brachial artery might be associated with late in-stent restenosis (ISR) after percutaneous coronary intervention (PCI). BACKGROUND:Simple and noninvasive identification of late ISR might help to select patients who require further angiographic evalu...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2005.04.055

    authors: Kitta Y,Nakamura T,Kodama Y,Takano H,Umetani K,Fujioka D,Saito Y,Kawabata K,Obata JE,Ichigi Y,Mende A,Kugiyama K

    更新日期:2005-08-16 00:00:00

  • Level of adenosine diphosphate receptor P2Y12 blockade during percutaneous coronary intervention predicts the extent of endothelial injury, assessed by circulating endothelial cell measurement.

    abstract:OBJECTIVES:We aimed to investigate whether clopidogrel-induced inhibition of platelet reactivity could reduce the level of circulating endothelial cells (CEC), reflecting the endothelial injury induced by percutaneous coronary intervention (PCI). BACKGROUND:Clopidogrel loading dose before percutaneous coronary angiopl...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.jacc.2010.01.072

    authors: Bonello L,Harhouri K,Sabatier F,Camoin-Jau L,Arnaud L,Baumstarck-Barrau K,Ait-Mokhtar O,Roubille F,Piot C,Lesavre N,Paganelli F,Dignat-George F

    更新日期:2010-09-21 00:00:00

  • Doppler and two-dimensional echocardiographic diagnosis of Björk-Shiley prosthetic valve malfunction: importance of interventricular septal motion and the timing of onset of valve flow.

    abstract::In a 69 year old woman with a "sticking" Björk-Shiley mitral prosthesis, the diagnosis was suggested by both the two-dimensional and the Doppler ultrasound examinations. In particular, the findings of early diastolic paradoxic septal motion, intermittent delayed opening of the prosthetic disc and variable timing of th...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(86)80443-0

    authors: Mann DL,Gillam LD,Marshall JE,King ME,Weyman AE

    更新日期:1986-10-01 00:00:00

  • Lessons from the past and promises for the future for carotid intima-media thickness.

    abstract::Carotid intima-media thickness (CIMT) measurements have been used in cardiovascular research for more than 2 decades. There is a wealth of evidence showing that CIMT can be assessed in a reproducible manner and that increased CIMT relates to unfavorable risk factor levels and atherosclerosis elsewhere in the arterial ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jacc.2011.12.061

    authors: Bots ML,Sutton-Tyrrell K

    更新日期:2012-10-23 00:00:00

  • Pulmonary Hypertension in Transcatheter Mitral Valve Repair for Secondary Mitral Regurgitation: The COAPT Trial.

    abstract:BACKGROUND:Pulmonary hypertension worsens prognosis in patients with heart failure (HF) and secondary mitral regurgitation (SMR). OBJECTIVES:This study sought to determine whether baseline pulmonary hypertension influences outcomes of transcatheter mitral valve repair (TMVr) in patients with HF with SMR. METHODS:In t...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2020.09.609

    authors: Ben-Yehuda O,Shahim B,Chen S,Liu M,Redfors B,Hahn RT,Asch FM,Weissman NJ,Medvedofsky D,Puri R,Kapadia S,Sannino A,Grayburn P,Kar S,Lim S,Lindenfeld J,Abraham WT,Mack MJ,Stone GW

    更新日期:2020-12-01 00:00:00

  • Transient right but not left ventricular dysfunction after strenuous exercise at high altitude.

    abstract:OBJECTIVES:We sought to evaluate whether prolonged exercise in ultramarathon runners results in left ventricular (LV) damage. BACKGROUND:Strenuous exercise has been reported to cause LV damage. METHODS:Fourteen runners who completed an ultramarathon at high altitude underwent echocardiography, finger-tip oximetry and...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(97)00179-4

    authors: Dávila-Román VG,Guest TM,Tuteur PG,Rowe WJ,Ladenson JH,Jaffe AS

    更新日期:1997-08-01 00:00:00

  • Contrast echocardiographic visualization of cough-induced right to left shunt through a patent foramen ovale.

    abstract::In a series of 24 consecutive patients referred to the echocardiography laboratory because of suspected patent foramen ovale, contrast two-dimensional and M-mode echocardiographic studies were performed during normal breathing and during two provocative tests: the Valsalva maneuver and cough. A right to left shunt was...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(84)80106-0

    authors: Dubourg O,Bourdarias JP,Farcot JC,Gueret P,Terdjman M,Ferrier A,Rigaud M,Bardet JC

    更新日期:1984-09-01 00:00:00

  • Pregnancy-associated plasma protein-A levels in patients with acute coronary syndromes: comparison with markers of systemic inflammation, platelet activation, and myocardial necrosis.

    abstract:OBJECTIVES:The goal of this study was to determine the predictive value of pregnancy-associated plasma protein-A (PAPP-A) in patients with acute coronary syndromes (ACS). BACKGROUND:Pregnancy-associated plasma protein-A is a zinc-binding matrix metalloproteinase abundantly expressed in eroded and ruptured plaques and ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2004.09.060

    authors: Heeschen C,Dimmeler S,Hamm CW,Fichtlscherer S,Simoons ML,Zeiher AM,CAPTURE Study Investigators.

    更新日期:2005-01-18 00:00:00

  • Optimal utilization of thrombolytic therapy for acute myocardial infarction: concepts and controversies.

    abstract::Timely administration of thrombolytic therapy decreases myocardial infarct size, lessens the incidence of congestive heart failure and improves survival. However, available data suggest that only 10% of patients with acute infarction in the United States receive thrombolytic drugs. Given the benefits of thrombolytic t...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/0735-1097(90)90482-5

    authors: Grines CL,DeMaria AN

    更新日期:1990-07-01 00:00:00

  • The patient with heart disease and the cardiovascular physician and surgeon: 1958-1983.

    abstract::The patient with heart disease and the physician providing cardiovascular health care have experienced dramatic change since the American College of Cardiology first published its journal 25 years ago. During the decade before 1958, cardiology and cardiovascular surgery emerged as specialties. Surgery by closed techni...

    journal_title:Journal of the American College of Cardiology

    pub_type: 历史文章,杂志文章

    doi:10.1016/s0735-1097(83)80005-9

    authors: Weinberg SL

    更新日期:1983-01-01 00:00:00

  • Angerlike behavioral state potentiates myocardial ischemia-induced T-wave alternans in canines.

    abstract:OBJECTIVES:The main goal of this study was to determine whether induction of an angerlike state can result in significant levels of T-wave alternans, a marker of electrical instability, in the normal and ischemic heart. BACKGROUND:Outbursts of anger have been implicated in the occurrence of myocardial infarction and s...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(01)01196-2

    authors: Kovach JA,Nearing BD,Verrier RL

    更新日期:2001-05-01 00:00:00

  • Long-term retention of cardiac resynchronization therapy.

    abstract:OBJECTIVES:The purpose of this study was to determine the frequency and causes of intermittent and permanent loss of cardiac resynchronization therapy (CRT) in patients who have undergone the successful implantation of a transvenous defibrillator that delivers CRT (CRT-D). BACKGROUND:The causes of loss of CRT have not...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.jacc.2004.03.054

    authors: Knight BP,Desai A,Coman J,Faddis M,Yong P

    更新日期:2004-07-07 00:00:00

  • Can nitrogen-13 ammonia kinetic modeling define myocardial viability independent of fluorine-18 fluorodeoxyglucose?

    abstract:OBJECTIVES:The hypothesis of this study was that evaluation of myocardial flow and metabolism using nitrogen-13 (N-13) ammonia kinetic modeling with dynamic positron emission tomographic (PET) imaging could identify regions of myocardial scar and viable myocardium as defined by fluorine-18 fluorodeoxyglucose (F-18 FDG)...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(96)00561-x

    authors: Beanlands RS,deKemp R,Scheffel A,Nahmias C,Garnett ES,Coates G,Johansen HL,Fallen E

    更新日期:1997-03-01 00:00:00

  • Incretin-Based Therapy for Diabetes: What a Cardiologist Needs to Know.

    abstract::Incretin-based therapies are effective glucose-lowering drugs that have an increasing role in the treatment of type 2 diabetes because of their efficacy, safety, and ease of use. Both glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors are commonly used for glycemic control as adjuncts to m...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jacc.2015.12.058

    authors: Waldrop G,Zhong J,Peters M,Rajagopalan S

    更新日期:2016-03-29 00:00:00

  • Assessment of coronary artery bypass graft disease using cardiovascular magnetic resonance determination of flow reserve.

    abstract:OBJECTIVES:The purpose of this study was to assess the value of cardiovascular magnetic resonance (CMR)-determined graft flow and flow reserve in differentiating significant from non-significant vein graft disease. BACKGROUND:In patients after coronary artery bypass grafting (CABG), non-invasive testing may be helpful...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0735-1097(02)02491-9

    authors: Bedaux WL,Hofman MB,Vyt SL,Bronzwaer JG,Visser CA,van Rossum AC

    更新日期:2002-11-20 00:00:00

  • Six month postoperative hemodynamics of the Hancock heterograft and the Björk-Shiley prosthesis: results of a Veterans Administration cooperative prospective randomized trial.

    abstract::In a Veterans Administration Cooperative Study involving 13 medical centers, 575 patients undergoing single valve replacement were prospectively randomized to receive either the standard Björk-Shiley prosthesis or the Hancock porcine heterograft (with a modified orifice for sizes 23 and smaller). The hemodynamic data ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0735-1097(88)90349-x

    authors: Khuri SF,Folland ED,Sethi GK,Souchek J,Oprian C,Wong M,Burchfiel C,Henderson WG,Hammermeister KE

    更新日期:1988-07-01 00:00:00

  • Long-term outcomes of older diabetic patients after percutaneous coronary stenting in the United States: a report from the National Cardiovascular Data Registry, 2004 to 2008.

    abstract:OBJECTIVES:The purpose of this study was to characterize long-term outcomes of percutaneous coronary intervention (PCI) in elderly diabetic patients in routine practice. BACKGROUND:Although drug-eluting stent (DES) implantation in diabetic patients is common practice, pivotal randomized trials enrolled <2,500 diabetic...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jacc.2012.08.993

    authors: Hillegass WB,Patel MR,Klein LW,Gurm HS,Brennan JM,Anstrom KJ,Dai D,Eisenstein EL,Peterson ED,Messenger JC,Douglas PS

    更新日期:2012-12-04 00:00:00

  • Hyperkalemia in Heart Failure.

    abstract::Disorders of potassium homeostasis can potentiate the already elevated risk of arrhythmia in heart failure. Heart failure patients have a high prevalence of chronic kidney disease, which further heightens the risk of hyperkalemia, especially when renin-angiotensin-aldosterone system inhibitors are used. Acute treatmen...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jacc.2016.06.060

    authors: Sarwar CM,Papadimitriou L,Pitt B,Piña I,Zannad F,Anker SD,Gheorghiade M,Butler J

    更新日期:2016-10-04 00:00:00

  • ST-segment deviation analysis of the admission 12-lead electrocardiogram as an aid to early diagnosis of acute myocardial infarction with a cardiac magnetic resonance imaging gold standard.

    abstract:OBJECTIVES:The purpose of this study was to validate existing 12-lead electrocardiographic (ECG) ST-segment elevation myocardial infarction (STEMI) criteria in the diagnosis of acute myocardial infarction (AMI) and the application of similar ST-segment depression (STEMI-equivalent) criteria with contrast-enhanced cardi...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2007.04.090

    authors: Martin TN,Groenning BA,Murray HM,Steedman T,Foster JE,Elliot AT,Dargie HJ,Selvester RH,Pahlm O,Wagner GS

    更新日期:2007-09-11 00:00:00

  • Influenza vaccination as secondary prevention for cardiovascular disease: a science advisory from the American Heart Association/American College of Cardiology.

    abstract::Evidence from cohort studies and a randomized clinical trial indicates that annual vaccination against seasonal influenza prevents cardiovascular morbidity and all-cause mortality in patients with cardiovascular conditions. The American Heart Association and American College of Cardiology recommend influenza immunizat...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,实务指引,评审

    doi:10.1016/j.jacc.2006.09.004

    authors: Davis MM,Taubert K,Benin AL,Brown DW,Mensah GA,Baddour LM,Dunbar S,Krumholz HM,American Heart Association.,American College of Cardiology.,American Association of Cardiovascular and Pulmonary Rehabilitation.,American Association of

    更新日期:2006-10-03 00:00:00

  • Determination of the stenotic aortic valve area in adults using Doppler echocardiography.

    abstract::The severity of aortic stenosis was evaluated by Doppler echocardiography in 48 adults (mean age 67 years) undergoing cardiac catheterization. Maximal Doppler systolic gradient correlated with peak to peak pressure gradient (r = 0.79, y = 0.63x + 25.2 mm Hg) and mean Doppler gradient correlated with mean pressure grad...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(86)80460-0

    authors: Otto CM,Pearlman AS,Comess KA,Reamer RP,Janko CL,Huntsman LL

    更新日期:1986-03-01 00:00:00

  • Magnetic resonance imaging of arrhythmogenic right ventricular dysplasia: sensitivity, specificity, and observer variability of fat detection versus functional analysis of the right ventricle.

    abstract:OBJECTIVES:The purpose of this study was to determine interobserver agreement for interpretation of magnetic resonance imaging (MRI) examinations of arrhythmogenic right ventricular dysplasia (ARVD) and to determine sensitivity and specificity of fat detection versus functional parameters measured by MRI. BACKGROUND:T...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2006.07.051

    authors: Tandri H,Castillo E,Ferrari VA,Nasir K,Dalal D,Bomma C,Calkins H,Bluemke DA

    更新日期:2006-12-05 00:00:00

  • Stem Cell-Derived Cardiomyocytes and Beta-Adrenergic Receptor Blockade in Duchenne Muscular Dystrophy Cardiomyopathy.

    abstract:BACKGROUND:Although cardiomyopathy has emerged as a leading cause of death in Duchenne muscular dystrophy (DMD), limited studies and therapies have emerged for dystrophic heart failure. OBJECTIVES:The purpose of this study was to model DMD cardiomyopathy using DMD patient-specific human induced pluripotent stem cell (...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2019.12.066

    authors: Kamdar F,Das S,Gong W,Klaassen Kamdar A,Meyers TA,Shah P,Ervasti JM,Townsend D,Kamp TJ,Wu JC,Garry MG,Zhang J,Garry DJ

    更新日期:2020-03-17 00:00:00

  • Transvascular catheter infiltration of the ductus arteriosus with formalin in the newborn lamb: a novel method of establishing and maintaining ductal patency.

    abstract:OBJECTIVES:This study sought to establish and maintain patency of the ductus arteriosus by a new method of transvascular formalin infiltration of the ductus arteriosus wall. BACKGROUND:Maintaining patency of the ductus arteriosus postnatally is necessary with many forms of congenital heart disease to ensure survival u...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(96)00128-3

    authors: Weber HS,Baylen BG,Banaszak P,Abt AB

    更新日期:1996-07-01 00:00:00