Abstract:
OBJECTIVES:We sought to examine the combined effect of hospital and physician volume of primary percutaneous coronary intervention (PCI) on in-hospital mortality. BACKGROUND:An inverse relationship between volume and outcome has been observed for both hospitals and physicians after primary PCI for acute myocardial infarction. METHODS:Using the New York State PCI registry, we examined yearly hospital volume, physician volume, and risk-adjusted mortality in 7,321 patients undergoing primary PCI for acute myocardial infarction. Risk-adjusted mortality rates for high-volume hospitals (>50 cases/year) and high-volume physicians (>10 cases/year) were compared with their respective low-volume counterparts. RESULTS:Primary PCI by high-volume hospitals (odds ratio [OR]: 0.58; 95% confidence interval [CI]: 0.38 to 0.88) and high-volume physicians (OR: 0.66; 95% CI: 0.48 to 0.92) was associated with lower odds of mortality. Furthermore, there was a significant interaction between hospital and physician volume on adjusted mortality (p = 0.02). Although unadjusted mortality was lower when primary PCI was performed by high-volume physicians in high-volume hospitals compared with low-volume physicians in low-volume hospitals (3.2% vs. 6.7%, p = 0.03), the risk-adjusted mortality rate was not statistically significant (3.8% vs. 8.4%, p = 0.09). In low-volume hospitals, the average risk-adjusted mortality rate for low-volume physicians was 8.4% versus 4.8% for high-volume physicians (OR: 1.44; 95% CI: 0.68 to 3.03). However, in high-volume hospitals, the risk-adjusted mortality rate for high-volume physicians was 3.8% versus 6.5% for low-volume physicians (OR: 0.58; 95% CI: 0.39 to 0.86). CONCLUSIONS:During primary PCI, physician experience significantly modifies the hospital volume-outcome relationship. Therefore, policymakers need to consider physician experience when developing strategies to improve access to primary PCI.
journal_name
J Am Coll Cardioljournal_title
Journal of the American College of Cardiologyauthors
Srinivas VS,Hailpern SM,Koss E,Monrad ES,Alderman MHdoi
10.1016/j.jacc.2008.09.056subject
Has Abstractpub_date
2009-02-17 00:00:00pages
574-579issue
7eissn
0735-1097issn
1558-3597pii
S0735-1097(08)03799-6journal_volume
53pub_type
杂志文章abstract:BACKGROUND:It is unclear whether the overall effectiveness and safety of direct oral anticoagulants (DOACs) are consistent in patients with nonvalvular atrial fibrillation (AF) and extremely low body weight (<50 kg). OBJECTIVES:This study compared DOACs with warfarin in AF patients with low body weight. METHODS:Using...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,多中心研究
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abstract::A large number of prosthetic heart valves (PHV) are being implanted in patients with both congenital and acquired valvular disease. Many of the recipients of such valves are women of childbearing age who desire to have children. The main issues involved with pregnancy in a patient with PHV include the selection of PHV...
journal_title:Journal of the American College of Cardiology
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更新日期:2005-11-15 00:00:00
abstract::In an attempt to determine whether mural thrombus in a dilated left ventricle is associated with specific flow patterns, a study was undertaken to assess qualitatively and quantitatively the flow characteristics by conventional pulsed and two-dimensional Doppler color flow examination. Forty patients with cardiomyopat...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(89)90230-1
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abstract:OBJECTIVES:The purpose of this study was to determine whether cilostazol reduces intimal hyperplasia in patients undergoing long zotarolimus-eluting stent implantation (stent length: ≥ 30 mm) for native long coronary lesions (length: ≥ 25 mm). BACKGROUND:Restenosis after drug-eluting stent implantation remains a signi...
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journal_title:Journal of the American College of Cardiology
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doi:10.1016/s0735-1097(97)00266-0
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(96)00002-2
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
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更新日期:2007-02-27 00:00:00
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pub_type: 杂志文章
doi:10.1016/s0735-1097(86)80381-3
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pub_type: 杂志文章
doi:10.1016/0735-1097(89)90573-1
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journal_title:Journal of the American College of Cardiology
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更新日期:2008-02-26 00:00:00
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doi:10.1016/j.jacc.2008.08.055
更新日期:2008-12-09 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(84)80277-6
更新日期:1984-06-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(89)90499-3
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(88)90403-2
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更新日期:1995-08-01 00:00:00
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更新日期:1993-10-01 00:00:00
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journal_title:Journal of the American College of Cardiology
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更新日期:1991-04-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(96)00274-4
更新日期:1996-10-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/j.jacc.2008.01.028
更新日期:2008-04-29 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/j.jacc.2005.02.076
更新日期:2005-06-21 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(00)00998-0
更新日期:2000-12-01 00:00:00
abstract::In adults with hypertrophic cardiomyopathy, the annual mortality rate from sudden death is 2 to 3%, and the finding of nonsustained ventricular tachycardia during electrocardiographic (ECG) monitoring provides a marker of the patient who is at increased risk. In the young, the annual mortality rate from sudden death i...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(88)90181-7
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVES:Apoptosis develops in several heart diseases, but the therapeutic options are limited. It was hypothesized that nicotine, which inhibits apoptosis in several cells, inhibits cardiac apoptosis induced by lipopolysaccharide (LPS). BACKGROUND:Over-the-counter nicotine produces sustained levels (10 to 25 ng/ml)...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(02)02820-6
更新日期:2003-02-05 00:00:00