Abstract:
BACKGROUND:We determined the genetic diversity of mycobacteria isolated from tuberculosis patients in Mbarara Uganda, using region of difference (RD) analysis and spacer oligonucleotide typing (spoligotyping). METHODS:Sputum samples were cultured on Lowenstein Jensen media. The isolates were characterized using RD analysis and spoligotyping. RESULTS:The majority (92.8%) of the patients were new cases, 60% were males and 44% were HIV positive with a mean age of 33.7 years. All the 125 isolates were identified as M.tuberculosis sensu stricto. Most (92.8%) of the isolates were modern strains. Spoligotyping revealed 79 spoligotype patterns, with an overall diversity of 63.2%. Sixty (48%) isolates formed 16 clusters each consisting of 2-15 isolates. Mst (59.2 %) of the isolates were Uganda genotype strains. The major shared spoligotypes in our sample were SIT 135 (T2-Uganda) with 12 isolates and SIT 128 (T2) with 5 isolates. Sixty nine (87%) patterns had not yet been defined in the SpolDB4.0.database. CONCLUSION:The TB epidemic in Mbarara is caused mainly by modern M.tuberculosis strains of the Uganda genotype. The wide diversity of strains may indicate that the majority of the TB cases are reactivation rather than re-infection. However this needs to be ascertained with more discriminative finger printing techniques.
journal_name
Afr Health Scijournal_title
African health sciencesauthors
Bazira J,Matte M,Asiimwe BB,Joloba LMsubject
Has Abstractpub_date
2010-12-01 00:00:00pages
306-11issue
4eissn
1680-6905issn
1729-0503journal_volume
10pub_type
杂志文章abstract:Background:Urinary tract infections (UTI) are frequently encountered medical complications of pregnancy. Objective:This study was aimed at analyzing the bacterial resistance in urogenital tract as well as the immunological profile amongst pregnant and non-pregnant women at Mbouda Ad-Lucem Hospital, Western Region of C...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v19i1.26
更新日期:2019-03-01 00:00:00
abstract:Background:Nitrate (NO3) is the most common chemical contaminant in the world's ground water aquifer. Oxidative stress has been proposed as a possible mechanism involved in NO3 toxicity on non-target organism. Objectives:The current study aimed to elucidate the potential protective effect of Telfairia occidentalis (pu...
journal_title:African health sciences
pub_type: 杂志文章
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journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v19i1.16
更新日期:2019-03-01 00:00:00
abstract::Congenital heart disease is an important cause of maternal morbidity and mortality during pregnancy. Pregnancy alters the circulatory and respiratory physiology with attendant deleterious effect on the mother with congenital heart disease and the foetus. Additional insult to the circulatory physiology by other factors...
journal_title:African health sciences
pub_type: 杂志文章
doi:
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Snake envenomation is a major public health problem of the Savannah regions of West Africa. Ocular manifestations of snakebites are rare with few reports documenting blindness as a complication. OBJECTIVE:To highlight an unusual manifestation of snake bites and its attendant problems. METHODS:A report of s...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v15i3.46
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Due to increasing stress, individual personality traits are becoming a significant contributor to CRT (Crash Related Trauma). In the present study, we hypothesized that there will be no difference in personality characteristics of CRT patients and control subjects and there will be no association between tra...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v16i3.27
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:The plant, Parquetina nigrescens is used in folklore medicine to treat diabetes mellitus and its complications in several parts of West Africa. OBJECTIVE:To determine the effect of Parquetina nigrescens extract on fasting blood glucose in alloxan-induced diabetic rats. METHODS:The blood glucose levels, com...
journal_title:African health sciences
pub_type: 杂志文章
doi:
更新日期:2010-09-01 00:00:00
abstract:Introduction:Hymenolepis nana is a zoonotic tapeworm with widespread distribution. The goal of the present study was to identify the parasite in the specimens collected from NorthWestern regions of Iran using PCR-sequencing method. Methods:A total of 1521 stool samples were collected from the study individuals. Initia...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v19i1.6
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:HIV/AIDS is a major public health problem in Cameroon which had a prevalence of 5.1% in 2010 with 141 new infections per day. The fear of voluntary counseling and testing (VCT) is an obstacle to HIV prevention. OBJECTIVES:To determine the prevalence of HIV-1, HIV-2 and HIV-1/HIV-2 co-infection among people ...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v12i3.5
更新日期:2012-09-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:To analyze the epidemiological characteristics and secular trends of the leading causes of death in China. METHODS:Data on the leading causes of death was collected from the Statistical Yearbook of China. Data for 11 years, from 2003 to 2013, was analyzed by regression analysis and chi-square test. RESULTS...
journal_title:African health sciences
pub_type: 杂志文章
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更新日期:2017-06-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v17i4.7
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Co-trimoxazole use is the standard of care for preventing Pneumocystis jirovecii pneumonia in sub-Saharan Africa but implementation remains slow. Co-trimoxazole is self- administered with uncertain adherence. Knowledge of co-trimoxazole use among HIV infected persons is unknown. OBJECTIVES:To assess knowled...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v15i1.7
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Over a third of the world's population is infected with the tuberculin bacteria. In 1993 WHO launched the DOTS-strategy to enhance treatment compliance. Despite Gambia's adaption in 1985 it falls below WHO target of 85% cure rate. The defaulter rate was 14% in 2001, which reached 16% in the urban areas of th...
journal_title:African health sciences
pub_type: 杂志文章
doi:
更新日期:2010-06-01 00:00:00
abstract:Background/Objective:In a project of telepathology (TP) between German pathologists and a hospital in Tanzania, trained technical assistants have uploaded digital histological images onto the internet-based platform ipath. The diagnoses from 486 paediatric specimens were analysed. Methods:The investigation included di...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v20i3.37
更新日期:2020-09-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:HIV/AIDS epidemic and sexual assault have emerged as the most serious public health problems in South Africa. The country has about 5-million HIV infected individuals. About a million women are raped every year. OBJECTIVES:To study the incidence of HIV infection in victims of sexual assaults. DESIGN:This i...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.5555/afhs.2005.5.3.207
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:South Africa has endorsed a World Health Assembly (WHA) resolution calling for control of soil-transmitted helminths (STHs). In Cape Town, services and housing that exist in old-established suburbs should minimise the prevalence of intestinal parasitic infections, even when residents are poor. Where families...
journal_title:African health sciences
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
abstract:Background:The risk of death from complications related to cancer of the cervix is a main health problem over the course of a woman's life in low income countries. It commonly affects women infected with HIV. Therefore, screening women infected with HIV should start in low income countries, including Ethiopia. Methods...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v19i1.46
更新日期:2019-03-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章,随机对照试验
doi:10.4314/ahs.v18i4.5
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:The decoration of interior spaces can lead to dangerous levels of indoor formaldehyde pollution. Exposure to indoor air pollution may be responsible for nearly 2 million deaths per year in developing countries. OBJECTIVES:To assess the prevalence of indoor formaldehyde pollution caused by decoration and res...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v13i1.19
更新日期:2013-03-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v19i2.10
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Substantial climate changes have led to the emergence and re-emergence of various infectious diseases worldwide, presenting an imperative need to explore the effects of meteorological factors on serious contagious disease incidences such as that of meningococcal meningitis (MCM). METHODS:The ...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v17i3.25
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVES:To investigate the pattern of referral for and utilisation of physiotherapy in the continuum of stroke care at a tertiary hospital in Ibadan, Nigeria. METHODS:Referral notes and medical records of patients admitted in the University College Hospital, Ibadan with a clinical diagnosis of stroke between Januar...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v17i1.11
更新日期:2017-03-01 00:00:00
abstract:Background:Mulago Hospital is a high volume referral hospital under the Makerere University School of Medicine and Health Sciences. Basic obstetric ultrasound is a useful skill that can aid patient care. Objectives:The purpose of the study was to assess the effectiveness of an intervention implemented to teach basic u...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v18i1.21
更新日期:2018-03-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:
更新日期:2011-03-01 00:00:00
abstract::We report an inbred Tunisian family, in which the proband manifested signs of hypohidrotic ectodermal dysplasia, subtotal amelia, scoliosis and left renal agenesis. Two other family members had the full clinical criteria of hypohidrotic ectodermal dysplasia, characterized by deficient sweat glands, hypodontia, hypopla...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.5555/afhs.2005.5.3.270
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVES:To evaluate the effectiveness of Botulinum toxin injection in the treatment of anal fissure. METHODS:38 patients (22 males, 16 females; mean age (SD) of 33.3 (8.3) years) who have presented to Surgical Outpatient Clinic at Al Ain Hospital, United Arab Emirates, with anal fissure in the period between June 2...
journal_title:African health sciences
pub_type: 临床试验,杂志文章
doi:10.5555/afhs.2007.7.1.14
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:Day case surgery services are increasing all over the world. The prevalence of postoperative pain after day surgery is found to be high. Little is known about the prevalence of postoperative pain, in Kenya, after day case surgeries. OBJECTIVE:To investigate the prevalence of postoperative pain after day sur...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v13i3.36
更新日期:2013-09-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00