Abstract:
:The computational platform ENVIRONMENT, developed to simulate stochastically reaction systems in varying compartmentalized conditions [Mavelli and Ruiz-Mirazo: Philos Trans R Soc Lond B Biol Sci 362:1789-1802, 2007; Physical Biology 7(3): 036002, 2010], is here applied to study the dynamic properties and stability of model protocells that start producing their own lipid molecules (e.g., phospholipids), which get inserted in previously self-assembled vesicles, made of precursor amphiphiles (e.g., fatty acids). Attention is mainly focused on the changes that this may provoke in the permeability of the compartment, as well as in its eventual osmotic robustness.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Ruiz-Mirazo K,Piedrafita G,Ciriaco F,Mavelli Fdoi
10.1007/978-1-4419-7046-6_70subject
Has Abstractpub_date
2011-01-01 00:00:00pages
689-96eissn
0065-2598issn
2214-8019journal_volume
696pub_type
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journal_title:Advances in experimental medicine and biology
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journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章
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journal_title:Advances in experimental medicine and biology
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journal_title:Advances in experimental medicine and biology
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doi:10.1007/5584_2015_5003
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pub_type: 杂志文章,评审
doi:10.1007/978-1-4614-4726-9_8
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更新日期:2019-01-01 00:00:00
abstract::Nitric oxide (NO) induces apoptotic cell death in murine RAW264.7 macrophages. To elucidate the mechanism underlying the inhibitory effect of taurine on NO-induced apoptosis, a cell was exposed to sodium nitroprusside (SNP), an NO donor, in the absence and presence of taurine. Taurine treatment prevented SNP-mediated ...
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abstract::The views presented in this article are the fruit of reflections and discussion with my colleagues at Valladolid and with the members of the Sleep Apnea Hypopnea Syndrome Group of the CIBERES (Spain). We have assembled the article in three sections. In the first one we provide a mechanistic description of obstructive ...
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abstract::Honokiol (C18H18O2) is a biphenolic natural product isolated from the bark and leaves of Magnolia plant spp. During the last decade or more, honokiol has been extensively studied for its beneficial effect against several diseases. Investigations have demonstrated that honokiol possesses anti-carcinogenic, anti-inflamm...
journal_title:Advances in experimental medicine and biology
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更新日期:2016-01-01 00:00:00
abstract::Recently advances in cancer genomics revealed the unexpected high frequencies of epigenetic abnormalities in human acute myeloid leukemia (AML). Accumulating data suggest that these leukemia-associated epigenetic factors play critical roles in both normal hematopoietic stem cells (HSCs) and leukemia stem cells (LSCs)....
journal_title:Advances in experimental medicine and biology
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journal_title:Advances in experimental medicine and biology
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abstract::The past few decades have seen tremendous advances in single-particle electron -cryo-microscopy (cryo-EM). The field has matured to the point that near-atomic resolution density maps can be generated for icosahedral viruses without the need for crystallization. In parallel, substantial progress has been made in determ...
journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章,评审
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更新日期:2012-01-01 00:00:00
abstract::Circular RNAs (circRNAs) are endogenously expressed non-coding RNAs discovered in the early 1990s as a transcriptional by-product of little importance. It was only recently that they were identified as a key player in regulating the gene expression by targeting and modulating the functions of microRNA, a process known...
journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章,评审
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更新日期:2018-01-01 00:00:00
abstract::Although prevalence estimates are imprecise, growing numbers of women in the United States are living longer with metastatic breast cancer, attributable at least in part to the availability of effective targeted therapies. Women living with metastatic disease are understudied, however, and substantial heterogeneity ex...
journal_title:Advances in experimental medicine and biology
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更新日期:2015-01-01 00:00:00