Abstract：
INTRODUCTION:The authors describe benefits of the recognised adverse effects of prostaglandin analogues on periocular structures in patients with unilateral proptosis and intraocular pressure rise. This case points to intentional consideration of prostaglandin analogue therapy in this selected cohort of patients with secondary ocular hypertension and proptosis. CASE DESCRIPTION:A 70-year-old gentleman who presented with a 1-week history of a red and painful right eye associated with tortuous and dilated episcleral blood vessels. Visual acuity was unaffected. A diagnosis of idiopathic orbital inflammatory disease was made by extraocular muscle biopsy. Two weeks later, the patient presented with worsening pain, reduced vision and raised intraocular pressure. The secondary ocular hypertension was successfully treated with topical preserved eye drops, including latanoprost, a prostaglandin analogue. Over 6 months, the patient developed drop intolerance and punctate keratopathy leading to therapy non-adherence. Interestingly, the patient reported improvement in periocular appearance related to prostaglandin-associated periorbitopathy. Ocular surface disease and intraocular pressures were subsequently managed with preservative-free eye drops. CONCLUSION:Secondary ocular hypertension is not an uncommon consequence of orbital disease. Prostaglandin analogue can act as a double-edged sword in the management of raised intraocular pressure by reducing eye pressure at the cost of developing adverse effects of prostaglandin-associated periorbitopathy. These adverse effects however can be beneficial in the aesthetic rehabilitation of proptosis and associated exposure keratopathy in patients with unilateral orbital disease and probably should be sought as first line treatment in those with proptosis and raised intraocular pressure.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Joganathan V,Cannon PS,Mercieca Kdoi
10.1177/1120672120905296subject
Has Abstractpub_date
2020-02-11 00:00:00pages
1120672120905296eissn
1120-6721issn
1724-6016pub_type
杂志文章abstract：PURPOSE:To compare diagnostic capabilities and agreement between Oculus-Spark perimetry and 3 procedures of glaucoma morphologic analysis. METHODS:A total of 102 normal eyes and 104 consecutive eyes with suspected or confirmed glaucoma (1 eye per subject) were analyzed in a prospective observational case-control study...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000233
更新日期：2013-05-01 00:00:00
abstract：PURPOSE:A novel application of pulsed electronic speckle pattern interferometry (PulseESPI) techniques in important corneal elasticity measurements is presented in this pilot study. For laser-ablative procedures like laser-assisted in situ keratomileusis, it has been found that elastic properties of the cornea have a r...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067211002000208
更新日期：2010-03-01 00:00:00
abstract：:To evaluate the present level of reliability of common ultrasonography prior to vitreoretinal surgery, we carried out a prospective study to compare preoperative ultrasonography data with direct intraoperative findings. A total of 228 eyes with different vitreoretinal disorders and opaque or clear media were studied. ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：PURPOSE:To evaluate changes in anterior chamber morphology with the Pentacam anterior segment analyzer and gonioscopy after laser peripheral iridotomy (LPI) in patients with primary angle closure glaucoma and narrow angle and to compare central corneal thickness measurements performed with Pentacam and ultrasound pachy...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067211002000211
更新日期：2010-03-01 00:00:00
abstract：PURPOSE:To investigate color perception and contrast sensitivity with and without additional glare in pseudophakic patients with a conventional intraocular lens (IOL) in one eye and a blue light-filtering IOL in the fellow eye. METHODS:Twenty-three bilaterally pseudophakic patients with a conventional IOL (AcrySof SA6...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210901900210
更新日期：2009-03-01 00:00:00
abstract：PURPOSE:To evaluate visual and anatomic outcomes following pars plana vitrectomy and intravitreal or subretinal tissue plasminogen activator for submacular hemorrhage in patients with age-related macular degeneration. METHODS:This was a retrospective study on patients with a minimum follow-up of 12 months undertaken a...
journal_title：European journal of ophthalmology
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更新日期：2019-12-09 00:00:00
abstract：PURPOSE:To study the functional results of macular surgery and determine pre-operative features associated with better final visual outcome. METHODS:Forty-two consecutive patients underwent surgical removal of subfoveal choroidal neovascularization (CNV), related to age-related macular degeneration (AMD) in 8 eyes, de...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210101100313
更新日期：2001-07-01 00:00:00
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journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000036
更新日期：2012-05-01 00:00:00
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journal_title：European journal of ophthalmology
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更新日期：2020-05-07 00:00:00
abstract：PURPOSE:To assess eye movements pattern during reading process in patients with primary open-angle glaucoma (POAG) using a microperimeter. METHODS:Thirty-two patients with POAG at early and moderate stage, according to Glaucoma Staging System 2, and 34 healthy age- and sex-matched subjects were included in the study. ...
journal_title：European journal of ophthalmology
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doi：10.5301/ejo.5000397
更新日期：2014-05-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy of inferior sutureless sclerotomies without subretinal fluid drainage for the treatment of bullous exudative retinal detachment secondary to diffuse retinal pigment epitheliopathy. METHODS:A retrospective interventional case series of eyes treated with two inferior postequatorial full-...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210801800618
更新日期：2008-11-01 00:00:00
abstract：PURPOSE:To report a case of a combined branch retinal artery and vein occlusion in a patient with hepatitis C treated with interferon and ribavirin. METHODS:A 29-year-old man with a 1-week history of sudden visual field defect and decrease of central visual acuity was examined. RESULTS:Ophthalmoscopy and fluorescein ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/EJO.2008.4623
更新日期：2005-01-01 00:00:00
abstract：PURPOSE:To describe the clinical features of a rare case of NBAS-SOPH-like mutations; to emphasize special aspects of the ocular and oro-facial regions. METHODS:Case report. CASE DESCRIPTION:We present a 5-year-old girl initially examined for her dysmorphic features, mental delay, strabismus, and high myopia. During ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672119836335
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVE:To investigate the systemic associations of central serous chorioretinopathy (CSCR) with help of clinical and biochemical investigations. DESIGN:Case-control study. PARTICIPANTS:Eighty seven CSCR patients (case) and 82 Asian-Indian patients with primary non-traumatic rhegmatogenous retinal detachment (contr...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120975698
更新日期：2020-11-25 00:00:00
abstract：:In 1958, Kearns and Sayre described a multisystem entity, now known as Kearns-Sayre syndrome (KSS). The syndrome is defined as exhibiting a triad of thus far unexplained degenerative conditions: progressive external ophthalmoplegia, retinal pigmentary degeneration, and heart block. Commonly accompanying findings inclu...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,评审
doi：
更新日期：1992-01-01 00:00:00
abstract：PURPOSE:To investigate the mean values of intraocular pressure (IOP) measured with noncontact tonometer (NCT) and evaluate the factors that may affect IOP. METHODS:A total of 850 subjects who were admitted to our clinic between March 2005 and February 2006 were recruited for the study. Subjects having blepharitis, con...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210901900109
更新日期：2009-01-01 00:00:00
abstract：PURPOSE:To describe our clinical experience with the efficacy and safety of micropulse transscleral cyclophotocoagulation as a treatment for glaucoma. METHODS:In this retrospective case series, we reviewed the charts of 95 consecutive patients with various glaucoma subtypes who underwent micropulse transscleral cyclop...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672119839303
更新日期：2020-07-01 00:00:00
abstract：PURPOSE:To evaluate persistency (time on initial therapy) and the clinical impact of latanoprost versus beta-blocker monotherapy in treating glaucoma. METHODS:This observational, multicenter, retrospective medical chart review study conducted in four European countries included patients with primary open-angle glaucom...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1177/112067210301304s03
更新日期：2003-07-01 00:00:00
abstract：PURPOSE::To describe a case of Posterior Keratoconus (keratoconus posticus); its clinical condition, corneal, refractive response to intracorneal ring implantation (MyoRing), anterior segment optical coherence tomography findings; and micro incisional cataract surgery outcome. METHODS::Case report. RESULTS::The case ...
journal_title：European journal of ophthalmology
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doi：10.1177/1120672118787436
更新日期：2019-01-01 00:00:00
abstract：PURPOSE:To look for ophthalmologic abnormalities in 15 patients with Wolfram syndrome, also known as DIDMOAD syndrome (diabetes insipidus, diabetes mellitus, optic atrophy and deafness). METHODS:Fifteen patients from four inbred families diagnosed as having Wolfram syndrome at the National Center for Diabetes, Endocri...
journal_title：European journal of ophthalmology
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更新日期：2002-03-01 00:00:00
abstract：PURPOSE:To evaluate the choroidal vascularity index of eyes for acute and chronic central serous chorioretinopathy patients using swept-source optical coherence tomography generated en-face scans. METHODS:This was a retrospective study, in which slabs of en-face optical coherence tomography scans, at 5 μm intervals, s...
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journal_title：European journal of ophthalmology
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doi：10.1177/112067210101100303
更新日期：2001-07-01 00:00:00
abstract：PURPOSE:To evaluate in a retrospective study the long-term usefulness of red 647 nm krypton and 670 nm diode laser for transscleral contact cyclophotocoagulation (CPC) in the treatment of therapy-resistant inflammatory glaucoma. METHODS:The authors treated 48 eyes of 38 consecutive patients (mean age 36.8 years, range...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
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更新日期：2007-07-01 00:00:00
abstract：OBJECTIVE:To identify complications associated with tumor-related lipid exudation (TRLE) after plaque radiotherapy of posterior uveal melanoma. METHODS:Comparative study including 294 patients with posterior uveal melanoma who developed TRLE after plaque radiotherapy (TRLE group) and 294 patients who did not develop ...
journal_title：European journal of ophthalmology
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更新日期：2013-05-01 00:00:00
abstract：:Blood flow in various tissues of the body shows spontaneous variations. The purpose of this study was to analyze variations over time in the blood flow of the optic nerve head. Blood flow was measured by the laser Doppler flowmeter (LDF) in 12 healthy volunteers, and analyzed by spectral Fourier analysis. The LDF tech...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：PURPOSE:To determine the magnitude and types of ocular disorders in children with Down syndrome in an African population and to assess to what extent these visual needs have been met. METHODS:This is a cross-sectional study of children with Down syndrome attending a school for the mentally challenged in Southeastern ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000222
更新日期：2013-05-01 00:00:00
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journal_title：European journal of ophthalmology
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更新日期：2012-09-01 00:00:00
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journal_title：European journal of ophthalmology
pub_type： 杂志文章
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更新日期：2020-05-01 00:00:00
abstract：:Electroretinogram (ERG) changes with age have been studied widely, but there is no general agreement about the age at which ERG parameters reach adult values. We studied 296 eyes from 148 healthy subjects, divided into 14 age groups, ranging from 1 week to 21 years. Although most of the maturational changes or ERG tak...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：PURPOSE:The purpose of this study was to assess indications and outcome of carotid Doppler ultrasound requested by ophthalmologists from an eye hospital over a period of three years. METHODS:This retrospective study was designed to analyse data for all patients referred to have carotid Doppler ultrasound from 1999 to ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2004-05-01 00:00:00
