当前位置： SCI文献检索 > ENVIRONMENT INTERNATIONAL期刊下所有文献 > An open source physiologically based kinetic model for the chicken (Gallus gallus domesticus): Calibration and validation for the prediction residues in tissues and eggs.

An open source physiologically based kinetic model for the chicken (Gallus gallus domesticus): Calibration and validation for the prediction residues in tissues and eggs.

Abstract：

:Xenobiotics from anthropogenic and natural origin enter animal feed and human food as regulated compounds, environmental contaminants or as part of components of the diet. After dietary exposure, a chemical is absorbed and distributed systematically to a range of organs and tissues, metabolised, and excreted. Physiologically based kinetic (PBK) models have been developed to estimate internal concentrations from external doses. In this study, a generic multi-compartment PBK model was developed for chicken. The PBK model was implemented for seven compounds (with log Kow range -1.37-6.2) to quantitatively link external dose and internal dose for risk assessment of chemicals. Global sensitivity analysis was performed for a hydrophilic and a lipophilic compound to identify the most sensitive parameters in the PBK model. Model predictions were compared to measured data according to dataset-specific exposure scenarios. Globally, 71% of the model predictions were within a 3-fold change of the measured data for chicken and only 7% of the PBK predictions were outside a 10-fold change. While most model input parameters still rely on in vivo experiments, in vitro data were also used as model input to predict internal concentration of the coccidiostat monensin. Future developments of generic PBK models in chicken and other species of relevance to animal health risk assessment are discussed.

journal_name

Environ Int

journal_title

Environment international

authors

Lautz LS,Nebbia C,Hoeks S,Oldenkamp R,Hendriks AJ,Ragas AMJ,Dorne JLCM

doi

10.1016/j.envint.2020.105488

subject

Has Abstract

pub_date

2020-03-01 00:00:00

pages

105488

eissn

0160-4120

issn

1873-6750

pii

S0160-4120(19)33959-5

journal_volume

136

pub_type

杂志文章

相关文献

ENVIRONMENT INTERNATIONAL文献大全
  • Child's buccal cell mitochondrial DNA content modifies the association between heart rate variability and recent air pollution exposure at school.

    abstract：BACKGROUND:Studies investigating short-term exposure to ambient air pollution and heart rate variability (HRV) suggest that particulate matter (PM) exposure is associated with reductions in measures of HRV. Mitochondria are sensitive to PM exposure and may represent a biologically relevant underlying mechanism. However...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2018.11.028

    authors： Saenen ND,Provost EB,Cuypers A,Kicinski M,Pieters N,Plusquin M,Vrijens K,De Boever P,Nawrot TS

    更新日期：2019-02-01 00:00:00

  • Burden of cause-specific mortality attributable to heat and cold: A multicity time-series study in Jiangsu Province, China.

    abstract：:Previous epidemiological studies primarily examined the temperature-related mortality burden of all-cause or cardiovascular diseases (CVD) and respiratory diseases. However, evidence on the heat- and cold-attributable mortality burden from other specific causes is limited. This paper aimed to systematically examine th...

    journal_title：Environment international

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.envint.2020.105994

    authors： Ma Y,Zhou L,Chen K

    更新日期：2020-11-01 00:00:00

  • Precise control of iron activating persulfate by current generation in an electrochemical membrane reactor.

    abstract：:Activated persulfate (PS) oxidation is promising for contaminant removal but a lack of controllable activation can lead to a loss of reagents and thus low contamination degradation. Herein, we have proposed and investigated an innovative method to control PS activation by introducing ion exchange membrane into electro...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2019.105024

    authors： Wu S,Liang G,Guan X,Qian G,He Z

    更新日期：2019-10-01 00:00:00

  • Species-specific biomagnification and habitat-dependent trophic transfer of halogenated organic pollutants in insect-dominated food webs from an e-waste recycling site.

    abstract：:Aquatic, amphibious, and terrestrial organisms in or around a pond that was contaminated by e-waste were collected and persistent halogenated organic pollutants (HOPs) for these species were analyzed. Based on the stable isotope and dietary composition, the aquatic and terrestrial food webs and several insect-dominate...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2020.105674

    authors： Liu Y,Luo X,Zeng Y,Tu W,Deng M,Wu Y,Mai B

    更新日期：2020-05-01 00:00:00

  • Significant elevation of human methylmercury exposure induced by the food trade in Beijing, a developing megacity.

    abstract：:Methylmercury (MeHg) poses health risks to humans worldwide. The investigation of a longer chain of biogeochemical MeHg transport from production to consumption than that addressed in previous studies could provide additional scientific foundation for the reduction of risks. The main objective of this study is to iden...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2019.105392

    authors： Liu M,Cheng M,Zhang Q,Hansen G,He Y,Yu C,Lin H,Zhang H,Wang X

    更新日期：2020-02-01 00:00:00

  • Health effects of multi-pollutant profiles.

    abstract：BACKGROUND:The association between exposure to particle mass and mortality is well established; however, there are still uncertainties as to whether certain chemical components are more harmful than others. Moreover, understanding the health effects associated with exposure to pollutant mixtures may lead to new regulat...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2014.05.023

    authors： Zanobetti A,Austin E,Coull BA,Schwartz J,Koutrakis P

    更新日期：2014-10-01 00:00:00

  • Evaluation of the usefulness of bird feathers as a non-destructive biomonitoring tool for organic pollutants: a comparative and meta-analytical approach.

    abstract：:In this study, we investigated whether bird feathers can be used as a non-destructive biomonitor for organic pollutants. We analysed the outermost tail feathers of 8 terrestrial and aquatic bird species from Belgium (8 species, n=108) for polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs) and org...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2006.11.011

    authors： Jaspers VL,Voorspoels S,Covaci A,Lepoint G,Eens M

    更新日期：2007-04-01 00:00:00

  • Differences in the seasonal variation of brominated and phosphorus flame retardants in office dust.

    abstract：:This study documents the temporal variability in concentrations of flame retardants (FRs) in floor dust from three offices in Beijing, China. Dust from Office A (OAD) was collected weekly from March to August, 2012, and sampling of dust from Office B and C (OBD and OCD) was conducted fortnightly (each two weeks) from ...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2013.12.011

    authors： Cao Z,Xu F,Covaci A,Wu M,Yu G,Wang B,Deng S,Huang J

    更新日期：2014-04-01 00:00:00

  • Generation of nano- and micro-sized organic pollutant emulsions in simulated road runoff.

    abstract：:A wide range of organic pollutants (OPs) are emitted from the road and traffic environment and transported with road runoff to receiving waters. To provide an understanding of the transport routes of OPs in the environment, an investigation was carried out with the aim to determine whether OPs are transported with nan...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2019.105140

    authors： Markiewicz A,Strömvall AM,Björklund K,Eriksson E

    更新日期：2019-12-01 00:00:00

  • Long-term study of environmental levels of dioxins and furans in the vicinity of a municipal solid waste incinerator.

    abstract：:From 1975 to 2004, a municipal solid waste incinerator (MSWI) was operating in Montcada (Barcelona, Catalonia, Spain). Because of the potential health risks derived from emission of pollutants by the facility, especially polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs), a long-term monitoring progra...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2005.09.002

    authors： Schuhmacher M,Domingo JL

    更新日期：2006-04-01 00:00:00

  • The impact of flood and post-flood cleaning on airborne microbiological and particle contamination in residential houses.

    abstract：:In January 2011, Brisbane, Australia, experienced a major river flooding event. We aimed to investigate its effects on air quality and assess the role of prompt cleaning activities in reducing the airborne exposure risk. A comprehensive, multi-parameter indoor and outdoor measurement campaign was conducted in 41 resid...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2014.04.001

    authors： He C,Salonen H,Ling X,Crilley L,Jayasundara N,Cheung HC,Hargreaves M,Huygens F,Knibbs LD,Ayoko GA,Morawska L

    更新日期：2014-08-01 00:00:00

  • Quantitative determination of volatile organic compounds in indoor dust using gas chromatography-UV spectrometry.

    abstract：:A novel technique, gas chromatography-UV spectrometry (GC-UV), was used to quantify volatile organic compounds (VOCs) in settled dust from 389 residences in Sweden. The dust samples were thermally desorbed in an inert atmosphere and evaporated compounds were concentrated by solid phase micro extraction and separated b...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2005.04.003

    authors： Nilsson A,Lagesson V,Bornehag CG,Sundell J,Tagesson C

    更新日期：2005-10-01 00:00:00

  • Concentrations of selected heavy metals in maternal blood and associated factors in rural areas in Shanxi Province, China.

    abstract：BACKGROUND:Animal experiments indicate that prenatal exposure to mercury (Hg), lead (Pb), cadmium (Cd) and arsenic (As) can induce fetal neural tube defects (NTDs). The objectives of this study were to determine the levels of maternal exposure to Hg, Pb, Cd and As during early pregnancy in rural areas of Shanxi Provinc...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2014.01.016

    authors： Jin L,Liu J,Ye B,Ren A

    更新日期：2014-05-01 00:00:00

  • Critical factors in assessing exposure to PBDEs via house dust.

    abstract：:Assessment of indoor exposure to polybrominated diphenyl ethers (PBDEs) requires a critical examination of methods that may influence exposure estimates and comparisons between studies. We measured PBDEs in residential dust collected from 20 homes in Boston, MA, to examine 5 key questions: 1) Does the choice of dust e...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2008.03.006

    authors： Allen JG,McClean MD,Stapleton HM,Webster TF

    更新日期：2008-11-01 00:00:00

  • Lolium perenne as a biomonitor of atmospheric levels of fluoride.

    abstract：:The aim of the present study was to develop a standardised protocol for the use of Lolium perenne cultures to biomonitor the surroundings of an aluminium smelter. Five ecological stations, which corresponded to air quality network monitoring sites pertaining to the smelter, were selected for study. Cultures of L. pere...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2006.10.004

    authors： Rey-Asensio A,Carballeira A

    更新日期：2007-05-01 00:00:00

  • Methylsiloxanes in plasma from potentially exposed populations and an assessment of the associated inhalation exposure risk.

    abstract：:Methylsiloxanes (MSs) are ubiquitous in indoor air and pose an important health risk. Thus, assessments of indoor inhalation exposure by measuring MSs levels in plasma are needed. In this study, we measured plasma MSs concentrations and evaluated daily indoor inhalation exposure in potentially exposed populations, inc...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2020.105931

    authors： Guo J,Zhou Y,Sun M,Cui J,Zhang B,Zhang J

    更新日期：2020-10-01 00:00:00

  • A case study on identification of airborne organic compounds and time courses of their concentrations in the cabin of a new car for private use.

    abstract：:The cabin of an automobile can be considered to be a part of the living environment because many people spend long periods of time during business, shopping, recreation or travel activities. However, little is known about the interior air contamination due to organic compounds diffusing from the interior materials use...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2005.04.009

    authors： Yoshida T,Matsunaga I

    更新日期：2006-01-01 00:00:00

  • Concentrations of endocrine disrupting chemicals in newborn blood spots and infant outcomes in the upstate KIDS study.

    abstract：BACKGROUND:Novel methodologies to quantify infant exposures to endocrine disrupting chemicals (EDCs) for population-based studies are needed. OBJECTIVES:We used newborn dried blood spots to quantify three EDCs and their associations with infant outcomes in the Upstate KIDS Cohort. METHODS:We measured bisphenol A (BPA...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2018.09.005

    authors： Bell EM,Yeung EH,Ma W,Kannan K,Sundaram R,Smarr MM,Buck Louis GM

    更新日期：2018-12-01 00:00:00

  • Polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDEs) in breast milk from Zhejiang, China.

    abstract：:Breast milk samples (n=74) from the general maternal population of Zhejiang province were analyzed for polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDEs). Samples were divided into urban and rural groups. Mean ∑PCDD/F, ∑PCB and ∑PBDE concent...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2011.04.004

    authors： Shen H,Ding G,Wu Y,Pan G,Zhou X,Han J,Li J,Wen S

    更新日期：2012-07-01 00:00:00

  • Assessing concentrations and health impacts of air quality management strategies: Framework for Rapid Emissions Scenario and Health impact ESTimation (FRESH-EST).

    abstract：:In air quality management, reducing emissions from pollutant sources often forms the primary response to attaining air quality standards and guidelines. Despite the broad success of air quality management in the US, challenges remain. As examples: allocating emissions reductions among multiple sources is complex and c...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2016.06.005

    authors： Milando CW,Martenies SE,Batterman SA

    更新日期：2016-09-01 00:00:00

  • Characterisation, dissemination and persistence of gentamicin resistant Escherichia coli from a Danish university hospital to the waste water environment.

    abstract：:The aim of the study was to investigate the potential spread of gentamicin resistant (GEN(R)) Escherichia coli isolates or GEN(R) determinants from a Danish university hospital to the waste water environment. Waste water samples were collected monthly from the outlets of the hospital bed wards and the inlet of the rel...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2007.07.011

    authors： Jakobsen L,Sandvang D,Hansen LH,Bagger-Skjøt L,Westh H,Jørgensen C,Hansen DS,Pedersen BM,Monnet DL,Frimodt-Møller N,Sørensen SJ,Hammerum AM

    更新日期：2008-01-01 00:00:00

  • A temporal trend study (1972-2008) of perfluorooctanesulfonate, perfluorohexanesulfonate, and perfluorooctanoate in pooled human milk samples from Stockholm, Sweden.

    abstract：:The widespread presence of perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorohexanesulfonate (PFHxS) in human general populations and their slow elimination profiles have led to renewed interest in understanding the potential human neonatal exposures of perfluoroalkyls (PFAs) from consumption of...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2010.08.014

    authors： Sundström M,Ehresman DJ,Bignert A,Butenhoff JL,Olsen GW,Chang SC,Bergman A

    更新日期：2011-01-01 00:00:00

  • Levels and trends of persistent organic pollutants in ringed seals (Phoca hispida) from Central West Greenland, with particular focus on polybrominated diphenyl ethers (PBDEs).

    abstract：:Polybrominated diphenyl ethers (PBDEs) and the organochlorine compounds polychlorinated biphenyls (PCBs), DDTs, HCB, chlordane-related pesticides, HCH and toxaphene were analysed in blubber of juvenile ringed seals from Central West Greenland collected between 1982 and 2006. The longest time series could be establishe...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2007.11.004

    authors： Vorkamp K,Rigét FF,Glasius M,Muir DC,Dietz R

    更新日期：2008-05-01 00:00:00

  • Efficiency of the activated carbon filtration in the natural organic matter removal.

    abstract：:The removal and transformation of natural organic matter were monitored in the different stages of the drinking water treatment train. Several methods to measure the quantity and quality of organic matter were used. The full-scale treatment sequence consisted of coagulation, flocculation, clarification by flotation, d...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2005.06.003

    authors： Matilainen A,Vieno N,Tuhkanen T

    更新日期：2006-04-01 00:00:00

  • Using deep learning to examine street view green and blue spaces and their associations with geriatric depression in Beijing, China.

    abstract：BACKGROUND:Residential green and blue spaces may be therapeutic for the mental health. However, solid evidence on the linkage between exposure to green and blue spaces and mental health among the elderly in non-Western countries is scarce and limited to exposure metrics based on remote sensing images (i.e., land cover ...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2019.02.013

    authors： Helbich M,Yao Y,Liu Y,Zhang J,Liu P,Wang R

    更新日期：2019-05-01 00:00:00

  • Future directions in air-quality science, policy, and education.

    abstract：:On February 12-15, 2001, more than 200 scientists, engineers, decision makers, and educators participated in a conference on the "Future Directions in Air Quality Research: Ecological, Atmospheric, Regulatory/Policy, and Educational Issues." Important perspectives are summarized from the keynote addresses of noted sci...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/S0160-4120(02)00155-1

    authors： Ginsburg EO,Cowling EB

    更新日期：2003-06-01 00:00:00

  • Pathways of Mycobacterium ulcerans infection: a review.

    abstract：:Buruli ulcer (BU), an often-deforming skin ulceration caused by Mycobacterium ulcerans (MU), is now considered by the World Health Organization to be the third most common mycobacterium infection. However, the reservoir of MU in the environment and the epidemiology of BU are poorly understood. The disease is prevalent...

    journal_title：Environment international

    pub_type： 杂志文章,评审

    doi：10.1016/j.envint.2006.01.002

    authors： Duker AA,Portaels F,Hale M

    更新日期：2006-05-01 00:00:00

  • Cluster-based bagging of constrained mixed-effects models for high spatiotemporal resolution nitrogen oxides prediction over large regions.

    abstract：BACKGROUND:Accurate estimation of nitrogen dioxide (NO2) and nitrogen oxide (NOx) concentrations at high spatiotemporal resolutions is crucial for improving evaluation of their health effects, particularly with respect to short-term exposures and acute health outcomes. For estimation over large regions like California,...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2019.04.057

    authors： Li L,Girguis M,Lurmann F,Wu J,Urman R,Rappaport E,Ritz B,Franklin M,Breton C,Gilliland F,Habre R

    更新日期：2019-07-01 00:00:00

  • Long- and short-term air pollution exposure and measures of arterial stiffness in the Framingham Heart Study.

    abstract：BACKGROUND:Studies of air pollution exposure and arterial stiffness have reported inconsistent results and large studies employing the reference standard of arterial stiffness, carotid-femoral pulse-wave velocity (CFPWV), have not been conducted. AIM:To study long-term exposure to ambient fine particles (PM2.5), proxi...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2018.08.060

    authors： Ljungman PLS,Li W,Rice MB,Wilker EH,Schwartz J,Gold DR,Koutrakis P,Benjamin EJ,Vasan RS,Mitchell GF,Hamburg NM,Mittleman MA

    更新日期：2018-12-01 00:00:00

  • Enhanced methane production by alleviating sulfide inhibition with a microbial electrolysis coupled anaerobic digestion reactor.

    abstract：:Anaerobic digestion (AD) of organics is a challenging task under high-strength sulfate (SO42-) conditions. The generation of toxic sulfides by SO42--reducing bacteria (SRB) causes low methane (CH4) production. This study investigated the feasibility of alleviating sulfide inhibition and enhancing CH4 production by usi...

    journal_title：Environment international

    pub_type： 杂志文章

    doi：10.1016/j.envint.2020.105503

    authors： Yuan Y,Cheng H,Chen F,Zhang Y,Xu X,Huang C,Chen C,Liu W,Ding C,Li Z,Chen T,Wang A

    更新日期：2020-03-01 00:00:00