Novelty seeking behaviour in Parkinson's disease.

Abstract:

:Novelty seeking can be a positive trait leading to creativity and innovation, but it is also related to increased risk of damaging addictive behaviour. We have assessed novelty seeking with a three armed bandit task, in which novel stimuli were occasionally introduced, replacing choice options from which the participants had been choosing. This allowed us to assess whether or not they would be prone to selecting novel stimuli. We tested 25 non impulsive patients with Parkinson's disease (PD) and 27 PD patients with impulsive compulsive behaviours (ICBs). Both patient groups were examined "on" and "off" dopaminergic medication in a counterbalanced order and their behaviour was compared with 24 healthy controls. We found that PD patients with ICBs were significantly more prone to choose novel options than either non impulsive PD patients or controls, regardless of medication status. Our findings suggest that attraction to novelty is a personality trait in all PD patients with ICBs which is independent of medication status.

journal_name

Neuropsychologia

journal_title

Neuropsychologia

authors

Djamshidian A,O'Sullivan SS,Wittmann BC,Lees AJ,Averbeck BB

doi

10.1016/j.neuropsychologia.2011.04.026

subject

Has Abstract

pub_date

2011-07-01 00:00:00

pages

2483-8

issue

9

eissn

0028-3932

issn

1873-3514

pii

S0028-3932(11)00226-0

journal_volume

49

pub_type

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