Evaluation of surrogate animal models of melioidosis.

abstract：:The Gram-positive anaerobic human pathogenic bacterium Atopobium vaginae causes most diagnosed cases of bacterial vaginosis as well as opportunistic infections in immunocompromised patients. In addition to its well-established role in carbohydrate metabolism, D-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from Str...

journal_title：Frontiers in microbiology

authors： Querol-García J,Fernández FJ,Marin AV,Gómez S,Fullà D,Melchor-Tafur C,Franco-Hidalgo V,Albertí S,Juanhuix J,Rodríguez de Córdoba S,Regueiro JR,Vega MC

更新日期：2017-04-10 00:00:00

abstract：:With the increasing amount of evidence linking certain disorders of the human body to a disturbed gut microbiota, there is a growing interest for compounds that positively influence its composition and activity through diet. Besides the consumption of probiotics to stimulate favorable bacterial communities in the huma...

journal_title：Frontiers in microbiology

authors： Rivière A,Selak M,Lantin D,Leroy F,De Vuyst L

更新日期：2016-06-28 00:00:00

abstract：:Bacterial colonization and biofilm development on medical devices can lead to infection. Antimicrobial peptide-coated surfaces may prevent such infections. Melimine and Mel4 are chimeric cationic peptides showing broad-spectrum antimicrobial activity once attached to biomaterials and are highly biocompatible in animal...

journal_title：Frontiers in microbiology

authors： Yasir M,Dutta D,Hossain KR,Chen R,Ho KKK,Kuppusamy R,Clarke RJ,Kumar N,Willcox MDP

更新日期：2020-01-22 00:00:00

abstract：:Infections due to meropenem-nonsusceptible bacterial strains (MNBSs) with meropenem minimum inhibitory concentrations (MICs) ≥ 16 mg/L have become an urgent problem. Currently, the optimal treatment strategy for these cases remains uncertain due to some limitations of currently available mono- and combination therapy ...

journal_title：Frontiers in microbiology

authors： Song X,Wu Y,Cao L,Yao D,Long M

更新日期：2019-11-29 00:00:00

abstract：:Radix pseudostellariae L. is a common and popular Chinese medication. However, continuous monoculture has increased its susceptibility to severe diseases. We identified two pathogenic microorganisms, Talaromyces helicus M. (KU355274) and Kosakonia sacchari W. (KU324465), and their antagonistic bacterium, Bacillus pumi...

journal_title：Frontiers in microbiology

authors： Wu H,Wu L,Wang J,Zhu Q,Lin S,Xu J,Zheng C,Chen J,Qin X,Fang C,Zhang Z,Azeem S,Lin W

更新日期：2016-03-17 00:00:00

abstract：:Several arenaviruses are highly pathogenic to humans, causing hemorrhagic fever. Discovery of anti-arenavirus drug candidates is urgently needed, although the molecular basis of the host- and organ-specific pathogenicity remains to be fully elucidated. The arenavirus Z protein facilitates production of virus-like part...

journal_title：Frontiers in microbiology

authors： Mpingabo PI,Urata S,Yasuda J

更新日期：2020-09-30 00:00:00

abstract：:As Cryptococcus neoformans mother cells generationally age, their cell walls become thicker and cell-wall associated virulence factors are upregulated. Antiphagocytic protein 1 (App1), and laccase enzymes (Lac1 and Lac2) are virulence factors known to contribute to virulence of C. neoformans during infection through i...

journal_title：Frontiers in microbiology

authors： Orner EP,Bhattacharya S,Kalenja K,Hayden D,Del Poeta M,Fries BC

更新日期：2019-11-07 00:00:00

abstract：:In the last decades, pollution of the environment by large scale use of antibiotics in agriculture and human medicine have led to increased antimicrobial resistance in both the environment and the host animal microbiome. Disturbances in the host microbiome can result in impaired immunity and reduced resilience of aqua...

journal_title：Frontiers in microbiology

authors： López Nadal A,Peggs D,Wiegertjes GF,Brugman S

更新日期：2018-10-29 00:00:00

abstract：:The pressure-assisted ultra-high temperature (PAUHT) system was built by using soybean oil as pressure-transmitting medium, and the multiple regression equation of soybean oil temperature change (ΔTP ) during pressurization as a function of initial temperature (Ti ) and set pressure (P) was developed: ΔTP = -13.45 + 0...

journal_title：Frontiers in microbiology

authors： Liang D,Zhang L,Wang X,Wang P,Liao X,Wu X,Chen F,Hu X

更新日期：2019-06-10 00:00:00

abstract：:In vitro and in vivo research based on cell lines and animals are likely to be insufficient in elucidating authentic biological and physiological phenomena mimicking human systems, especially for generating pre-clinical data on targets and biomarkers. There is an obvious need for a model that can further bridge the ga...

journal_title：Frontiers in microbiology

authors： Tan KS,Yan Y,Koh WLH,Li L,Choi H,Tran T,Sugrue R,Wang Y,Chow VT

更新日期：2018-11-14 00:00:00

abstract：:Shigella spp., the etiological agent of shigellosis or "bacillary dysentery," are responsible for considerable morbidity and mortality in excess of a million deaths globally per year. Although PCR-based techniques (such as PCR-based dipstick biosensors) have been used for the molecular diagnosis of infectious disease,...

journal_title：Frontiers in microbiology

authors： Wang Y,Wang Y,Xu J,Ye C

更新日期：2016-11-18 00:00:00

abstract：:Based on the complete genome of Cyanothece ATCC 51142, the oriCs of both the circular and linear chromosomes in Cyanothece ATCC 51142 have been predicted by utilizing a web-based system Ori-Finder. Here, we provide experimental support for the results of Ori-Finder to identify the replication origins of Cyanothece ATC...

journal_title：Frontiers in microbiology

authors： Huang H,Song CC,Yang ZL,Dong Y,Hu YZ,Gao F

更新日期：2015-12-10 00:00:00

abstract：:The High Arctic is dominated by polar desert habitats whose microbial communities are poorly understood. In this study, we used next generation sequencing to describe the α- and β-diversity of microbial communities in polar desert soils from the Kongsfjorden region of Svalbard. Ten phyla dominated the soils and accoun...

journal_title：Frontiers in microbiology

authors： McCann CM,Wade MJ,Gray ND,Roberts JA,Hubert CR,Graham DW

更新日期：2016-03-31 00:00:00

abstract：:Mutations in the MEFV gene, which encodes the protein named pyrin (also called marenostrin or TRIM20), are associated with the autoinflammatory disease familial Mediterranean fever (FMF). Recent genetic and immunologic studies uncovered novel functions of pyrin and raised several new questions in relation to FMF patho...

journal_title：Frontiers in microbiology

authors： Manukyan G,Aminov R

更新日期：2016-03-31 00:00:00

abstract：:Fungi transcriptionally upregulate expression of azole efflux pumps and ergosterol biosynthesis pathway genes when exposed to antifungal agents that target ergosterol biosynthesis. To date, these transcriptional responses have been shown to be dependent on the presence of the azoles and/or depletion of ergosterol. Usi...

journal_title：Frontiers in microbiology

authors： Hu C,Zhou M,Wang W,Sun X,Yarden O,Li S

更新日期：2018-01-17 00:00:00

abstract：:The taxonomically diverse rhizosphere microbiome contributes to plant nutrition, growth and health, including protection against soil-borne pathogens. We previously showed that breeding for Fusarium-resistance in common bean changed the rhizosphere microbiome composition and functioning. Here, we assessed the impact o...

journal_title：Frontiers in microbiology

authors： Mendes LW,de Chaves MG,Fonseca MC,Mendes R,Raaijmakers JM,Tsai SM

更新日期：2019-10-01 00:00:00

abstract：:Bacterial cells are surrounded by an exoskeleton-like structure, the cell wall, composed primarily of the peptidoglycan (PG) sacculus. This structure is made up of glycan strands cross-linked by short peptides generating a covalent mesh that shapes bacteria and prevents their lysis due to their high internal osmotic p...

journal_title：Frontiers in microbiology

authors： Yadav AK,Espaillat A,Cava F

更新日期：2018-08-31 00:00:00

abstract：:Salmonella enterica is the leading foodborne pathogen associated with outbreaks involving low-moisture foods (LMFs). However, the genes involved in Salmonella's long-term survival on LMFs remain poorly characterized. In this study, in-shell pistachios were inoculated with Tn5-based mutant libraries of S. Enteritidis P...

journal_title：Frontiers in microbiology

authors： Jayeola V,McClelland M,Porwollik S,Chu W,Farber J,Kathariou S

更新日期：2020-05-15 00:00:00

abstract：:The abundant and diverse microorganisms that inhabit aquatic systems are both determinants and indicators of aquatic health, providing essential ecosystem services such as nutrient cycling but also causing harmful blooms and disease in impacted habitats. Estuaries are among the most urbanized coastal ecosystems and as...

journal_title：Frontiers in microbiology

authors： Jeffries TC,Schmitz Fontes ML,Harrison DP,Van-Dongen-Vogels V,Eyre BD,Ralph PJ,Seymour JR

更新日期：2016-01-26 00:00:00

abstract：:Bacteria in nature are usually found in complex multicellular structures, called biofilms. One common form of a biofilm is pellicle-a floating mat of bacteria formed in the water-air interphase. So far, our knowledge on the basic mechanisms underlying the formation of biofilms at air-liquid interfaces is not complete....

journal_title：Frontiers in microbiology

authors： Steinberg N,Rosenberg G,Keren-Paz A,Kolodkin-Gal I

更新日期：2018-03-29 00:00:00

abstract：:The purpose of present study was the simulation of an oil spill accompanied by burial of significant amount of petroleum hydrocarbons (PHs) in coastal sediments. Approximately 1000 kg of sediments collected in Messina harbor were spiked with Bunker C furnace fuel oil (6500 ppm). The rapid consumption of oxygen by aero...

journal_title：Frontiers in microbiology

authors： Genovese M,Crisafi F,Denaro R,Cappello S,Russo D,Calogero R,Santisi S,Catalfamo M,Modica A,Smedile F,Genovese L,Golyshin PN,Giuliano L,Yakimov MM

更新日期：2014-04-14 00:00:00

abstract：:Objective: To elucidate whether the genetic platforms of blaCTX-M contribute to the phenotypes of multi-drug-resistance (MDR) in the first carbapenemase-producing K. pneumoniae strains isolated in Chile. Method: Twenty-two carbapenemase-producing K. pneumoniae strains isolated from different Chilean patients and hospi...

journal_title：Frontiers in microbiology

authors： Carrasco-Anabalón S,Vera-Leiva A,Quezada-Aguiluz M,Morales-Rivera MF,Lima CA,Fernández J,Ulloa S,Domínguez M,González-Rocha G,Bello-Toledo H

更新日期：2018-03-06 00:00:00

abstract：:Flow cytometric analysis is a reliable and convenient method for investigating molecules at the single cell level. Previously, recombinant human immunodeficiency virus type 1 (HIV-1) strains were constructed that express a fluorescent reporter, either enhanced green fluorescent protein, or DsRed, which allow the monit...

journal_title：Frontiers in microbiology

authors： Terahara K,Yamamoto T,Mitsuki YY,Shibusawa K,Ishige M,Mizukoshi F,Kobayashi K,Tsunetsugu-Yokota Y

更新日期：2012-01-10 00:00:00

abstract：:The lumenal surfaces of human body are lined by a monolayer of epithelia that together with mucus secreting cells and specialized immune cells form the mucosal barrier. This barrier is one of the most fundamental components of the innate immune system, protecting organisms from the vast environmental microbiota. The m...

journal_title：Frontiers in microbiology

authors： Engel J,Eran Y

更新日期：2011-05-26 00:00:00

abstract：:Late blight, caused by the oomycete Phytophthora infestans, is the most devastating disease of potato. In organic farming, late blight is controlled by repeated applications of copper-based products, which negatively impact the environment. To find alternative solutions for late blight management, we have previously i...

journal_title：Frontiers in microbiology

authors： Guyer A,De Vrieze M,Bönisch D,Gloor R,Musa T,Bodenhausen N,Bailly A,Weisskopf L

更新日期：2015-11-27 00:00:00

abstract：:Molecular methods have emerged as the most reliable techniques to detect and characterize pathogenic Escherichia coli. These molecular techniques include conventional single analyte and multiplex PCR, PCR followed by microarray detection, pulsed-field gel electrophoresis (PFGE), and whole genome sequencing. The choice...

journal_title：Frontiers in microbiology

authors： Carter JM,Lin A,Clotilde L,Lesho M

更新日期：2016-05-20 00:00:00

abstract：:Staphylococcus aureus is one of the most common causes of zoonotic agent in the world, which are attributable to the contamination of food with enterotoxins. In this study, a total of 1,150 S. aureus isolates were cultured from 27,000 retail foods items from 203 cities of 24 provinces in China in 2015 and were test fo...

journal_title：Frontiers in microbiology

authors： Wang W,Baloch Z,Jiang T,Zhang C,Peng Z,Li F,Fanning S,Ma A,Xu J

更新日期：2017-11-21 00:00:00

abstract：:Baiyunbian baijiu, the most popular miscellaneous-flavor baijiu in China, has been widely consumed for decades. Similar to many Chinese baijiu, Baiyunbian baijiu is fermented in five successive batches every year. Sensory analysis demonstrated that the raw baijiu obtained from the last two fermentation batches always ...

journal_title：Frontiers in microbiology

authors： Liu P,Miao L

更新日期：2020-01-31 00:00:00

abstract：:Background: The gut microbiota is increasingly recognized as playing an important role in the development of obesity, but the influence of gender remains elusive. Using a large cohort of Chinese adults, our study aimed to identify differences in gut microbiota as a function of body mass index (BMI) and investigate gen...

journal_title：Frontiers in microbiology

authors： Gao X,Zhang M,Xue J,Huang J,Zhuang R,Zhou X,Zhang H,Fu Q,Hao Y

更新日期：2018-06-22 00:00:00

abstract：:The nitrogenase enzyme, which catalyzes the reduction of N2 gas to NH4+, occurs as three separate isozyme that use Mo, Fe-only, or V. The majority of global nitrogen fixation is attributed to the more efficient 'canonical' Mo-nitrogenase, whereas Fe-only and V-('alternative') nitrogenases are often considered 'backup'...

journal_title：Frontiers in microbiology

authors： McRose DL,Zhang X,Kraepiel AM,Morel FM

更新日期：2017-02-28 00:00:00